Drosophila melanogaster

200 known processes

E2f (Dmel_CG6376)

E2F transcription factor

(Aliases: E(var)3-93E,drosE2F1,DmE2F-1,E(Sev-CycE)3A,dE2f1,e2f1,l(3)j3C2,DRTF1/E2F,Dmel\CG6376,l(3)07172,e2f,CG6376,E(var)93E,Dp,l(3)rM729,E2f1,E2F-1,dE2F1,dE2F,l(3)j3B1,de2f1,Evar(3)164,E2F1,E2F,E(var)3-95E,dE2f,def21)

E2f biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742230.436
Human
regulation of cell cycle phase transitionGO:19019871300.273
Human Fly
intrinsic apoptotic signaling pathwayGO:0097193160.262
Human Mouse
positive regulation of rna metabolic processGO:00512542710.243
regulation of cell differentiationGO:00455953020.222
dorsal ventral axis specificationGO:0009950660.211
Fly
deathGO:00162652840.200
nuclear divisionGO:00002803320.193
regionalizationGO:00030024160.190
Fly
regulation of cell cycleGO:00517262910.186
nurse cell apoptotic processGO:0045476170.155
regulation of reproductive processGO:2000241540.154
organelle fissionGO:00482853400.136
positive regulation of macromolecule biosynthetic processGO:00105572830.136
regulation of multi organism processGO:00439001310.134
tissue morphogenesisGO:00487292970.127
positive regulation of gene expressionGO:00106282900.127
negative regulation of cell cycle phase transitionGO:19019881030.126
Fly
positive regulation of cellular biosynthetic processGO:00313283160.126
imaginal disc derived wing morphogenesisGO:00074763370.122
imaginal disc derived appendage morphogenesisGO:00351143950.122
regulation of apoptotic processGO:00429811300.117
regulation of nurse cell apoptotic processGO:004547790.116
positive regulation of macromolecule metabolic processGO:00106044050.116
positive regulation of nitrogen compound metabolic processGO:00511733540.116
axis specificationGO:00097981670.113
Fly
regulation of mitotic cell cycleGO:00073461900.108
Human Fly
cell cycle phase transitionGO:00447701400.106
Human Mouse Fly
mitotic nuclear divisionGO:00070672130.106
regulation of mitotic cell cycle phase transitionGO:19019901300.104
Human Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.100
imaginal disc derived appendage developmentGO:00487373990.095
phagocytosisGO:00069092150.095
regulation of cell cycle processGO:00105641810.089
Human Fly
dna metabolic processGO:00062592270.085
negative regulation of mitotic cell cycle phase transitionGO:19019911030.083
Fly
protein complex assemblyGO:00064612000.082
catabolic processGO:00090564090.081
organic substance catabolic processGO:19015753080.081
macromolecular complex assemblyGO:00650032560.080
vesicle mediated transportGO:00161923810.079
response to temperature stimulusGO:00092661060.077
dna integrity checkpointGO:0031570810.074
Human
programmed cell deathGO:00125012570.074
apoptotic process involved in developmentGO:1902742200.073
cell deathGO:00082192790.072
organophosphate metabolic processGO:00196371950.070
carbohydrate derivative metabolic processGO:19011352170.070
establishment or maintenance of cell polarityGO:00071631670.070
protein localizationGO:00081042840.067
positive regulation of multi organism processGO:0043902400.065
embryonic axis specificationGO:00005781070.065
Fly
response to abiotic stimulusGO:00096283410.064
Rat
microtubule organizing center organizationGO:00310231680.063
embryonic pattern specificationGO:00098801740.063
Fly
establishment of protein localizationGO:00451841630.062
organonitrogen compound metabolic processGO:19015643180.060
nucleobase containing compound catabolic processGO:00346551650.060
pole plasm assemblyGO:0007315610.059
transcription from rna polymerase ii promoterGO:00063663680.059
dorsal ventral pattern formationGO:00099531330.058
Fly
mitotic dna integrity checkpointGO:0044774750.058
cellular catabolic processGO:00442483720.057
heterocycle catabolic processGO:00467001660.057
cellular nitrogen compound catabolic processGO:00442701650.056
blastoderm segmentationGO:00073501590.056
Fly
intracellular signal transductionGO:00355563000.056
Human Mouse
oocyte axis specificationGO:00073091080.056
Fly
cellular macromolecule localizationGO:00707272200.053
body morphogenesisGO:001017120.053
small molecule metabolic processGO:00442813050.052
regulation of molecular functionGO:00650092170.051
phosphorylationGO:00163102940.051
mitotic cell cycle checkpointGO:0007093880.051
aromatic compound catabolic processGO:00194391660.050
compound eye morphogenesisGO:00017452490.049
nucleoside phosphate metabolic processGO:00067531620.048
regulation of anatomical structure morphogenesisGO:00226032420.048
organic cyclic compound catabolic processGO:19013611680.048
post embryonic appendage morphogenesisGO:00351203850.048
cellular protein modification processGO:00064644380.047
morphogenesis of an epitheliumGO:00020092760.047
purine ribonucleotide metabolic processGO:00091501450.047
regulation of catabolic processGO:00098941700.046
regulation of cell shapeGO:00083601130.045
positive regulation of nucleic acid templated transcriptionGO:19035082660.044
single organism biosynthetic processGO:00447112060.044
regulation of catalytic activityGO:00507901850.044
epidermis developmentGO:0008544650.043
endocytosisGO:00068973100.042
segmentationGO:00352822070.042
Fly
nucleoside triphosphate metabolic processGO:00091411200.041
cell proliferationGO:00082832990.041
positive regulation of biosynthetic processGO:00098913160.041
cell cycle checkpointGO:0000075950.040
Human
positive regulation of rna biosynthetic processGO:19026802660.040
mitotic cell cycle phase transitionGO:00447721380.040
Human Mouse Fly
anterior posterior pattern specificationGO:00099521360.040
Fly
positive regulation of apoptotic processGO:0043065470.039
appendage morphogenesisGO:00351073970.039
columnar cuboidal epithelial cell developmentGO:00020662490.039
ovarian follicle cell developmentGO:00307072480.038
mrna metabolic processGO:00160711240.038
mitotic dna damage checkpointGO:0044773740.038
protein modification processGO:00362114380.038
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.038
negative regulation of macromolecule biosynthetic processGO:00105582700.038
developmental maturationGO:00217001720.038
Fly
rna localizationGO:00064031150.037
cell divisionGO:00513012480.037
establishment of localization in cellGO:00516494020.036
regulation of transcription from rna polymerase ii promoterGO:00063573780.035
regulation of programmed cell deathGO:00430671520.035
regulation of organelle organizationGO:00330431960.035
ribonucleotide metabolic processGO:00092591450.035
tube developmentGO:00352952440.035
regulation of cellular catabolic processGO:00313291570.035
positive regulation of response to stimulusGO:00485843230.035
purine nucleotide metabolic processGO:00061631460.034
skin developmentGO:0043588650.034
apoptotic processGO:00069151590.034
response to external biotic stimulusGO:00432072930.032
nucleobase containing small molecule metabolic processGO:00550861740.032
mitotic g2 dna damage checkpointGO:0007095690.032
intracellular protein transportGO:00068861040.031
regulation of cellular localizationGO:00603411360.031
regulation of protein metabolic processGO:00512462560.030
intracellular transportGO:00469072280.030
pole plasm oskar mrna localizationGO:0045451460.030
purine nucleoside triphosphate metabolic processGO:00091441190.030
single organism catabolic processGO:00447122280.030
mitotic g2 m transition checkpointGO:0044818700.030
positive regulation of molecular functionGO:00440931360.029
epithelial cell differentiationGO:00308553220.029
chromosome organizationGO:00512763600.029
regulation of localizationGO:00328792750.029
response to organic cyclic compoundGO:0014070890.029
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.028
negative regulation of cell cycle g1 s phase transitionGO:1902807130.028
Fly
cytoplasm organizationGO:0007028640.027
purine ribonucleoside triphosphate catabolic processGO:00092071080.027
negative regulation of cell cycle processGO:00109481090.027
Fly
nucleotide metabolic processGO:00091171610.027
cell cycle g1 s phase transitionGO:0044843310.027
Human Mouse Fly
epithelial cell developmentGO:00020642740.027
pole plasm mrna localizationGO:0019094490.027
negative regulation of multicellular organismal processGO:00512411420.027
Worm
carbohydrate derivative biosynthetic processGO:1901137850.027
rna processingGO:00063961470.027
negative regulation of developmental processGO:00510932010.026
Worm
columnar cuboidal epithelial cell differentiationGO:00020652560.026
cellular response to biotic stimulusGO:007121640.026
oocyte developmentGO:00485991240.026
Fly
ribonucleoside metabolic processGO:00091191270.026
regulation of phosphorus metabolic processGO:00511742100.026
nucleoside metabolic processGO:00091161270.026
anterior posterior axis specification embryoGO:00085951030.026
Fly
response to oxygen containing compoundGO:19017002000.026
Rat
wing disc morphogenesisGO:00074723440.025
pole plasm rna localizationGO:0007316520.025
mitotic spindle organizationGO:00070522200.025
ras protein signal transductionGO:0007265880.025
lipid metabolic processGO:00066291210.025
protein localization to chromatinGO:007116830.025
positive regulation of phosphorus metabolic processGO:00105621390.025
cellular response to lipopolysaccharideGO:007122230.025
anterior posterior axis specificationGO:00099481090.024
Fly
organic substance transportGO:00717022570.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
small gtpase mediated signal transductionGO:0007264880.024
proteolysisGO:00065081920.024
protein transportGO:00150311550.024
regulation of cell deathGO:00109411730.024
appendage developmentGO:00487364010.024
response to bacteriumGO:00096171980.024
positive regulation of cell deathGO:0010942690.023
protein complex biogenesisGO:00702712010.023
embryonic morphogenesisGO:00485982060.023
positive regulation of developmental processGO:00510941430.023
innate immune responseGO:00450871440.023
chromatin modificationGO:00165681470.023
apoptotic signaling pathwayGO:0097190270.023
Human Mouse
purine nucleoside catabolic processGO:00061521120.023
positive regulation of phosphate metabolic processGO:00459371390.022
dna damage checkpointGO:0000077780.022
Human
ribose phosphate metabolic processGO:00196931450.022
spindle organizationGO:00070512530.022
positive regulation of signalingGO:00230562430.022
regulation of cellular protein metabolic processGO:00322682430.022
cellular response to oxygen containing compoundGO:1901701790.022
Rat
cell maturationGO:00484691440.022
Fly
cellular response to chemical stimulusGO:00708871990.022
Rat
purine containing compound catabolic processGO:00725231120.022
nucleotide catabolic processGO:00091661090.022
regulation of growthGO:00400082330.021
morphogenesis of follicular epitheliumGO:0016333360.021
nucleoside phosphate catabolic processGO:19012921100.021
regulation of mrna metabolic processGO:1903311720.021
positive regulation of nurse cell apoptotic processGO:004585050.021
cytoplasmic transportGO:00164821300.021
cellular response to molecule of bacterial originGO:007121930.021
ribonucleoside triphosphate catabolic processGO:00092031080.021
positive regulation of catabolic processGO:00098961050.021
macromolecule catabolic processGO:00090571610.021
purine nucleotide catabolic processGO:00061951090.021
gene silencing by rnaGO:0031047570.021
positive regulation of protein metabolic processGO:00512471280.021
single organism cellular localizationGO:19025801800.021
purine ribonucleoside catabolic processGO:00461301120.020
response to lipopolysaccharideGO:003249640.020
glycosyl compound metabolic processGO:19016571270.020
regulation of mrna processingGO:0050684710.020
purine ribonucleoside triphosphate metabolic processGO:00092051190.020
purine nucleoside metabolic processGO:00422781270.020
ribonucleotide catabolic processGO:00092611090.020
posttranscriptional regulation of gene expressionGO:00106081450.020
Human
purine nucleoside triphosphate catabolic processGO:00091461080.020
regulation of response to stressGO:00801342000.020
mitotic sister chromatid segregationGO:0000070870.020
response to organic substanceGO:00100332840.020
Rat
response to biotic stimulusGO:00096072940.020
regulation of anatomical structure sizeGO:00900661630.019
single organism intracellular transportGO:19025822070.019
cellular response to organic substanceGO:00713101320.019
Rat
protein alkylationGO:0008213430.019
purine containing compound metabolic processGO:00725211550.019
cell type specific apoptotic processGO:0097285380.019
positive regulation of intracellular signal transductionGO:19025331160.019
oxoacid metabolic processGO:00434361030.019
regulation of chromosome organizationGO:0033044640.019
digestive tract developmentGO:00485651490.019
chromatin remodelingGO:0006338720.019
carbohydrate derivative catabolic processGO:19011361180.019
negative regulation of transcription dna templatedGO:00458922370.019
nucleosome organizationGO:0034728590.019
connective tissue developmentGO:006144830.019
spindle assemblyGO:0051225800.019
eye developmentGO:00016543230.019
cellular macromolecule catabolic processGO:00442651360.019
g2 dna damage checkpointGO:0031572690.019
single organism carbohydrate metabolic processGO:0044723720.019
mrna processingGO:00063971040.019
oocyte differentiationGO:00099941450.019
Fly
negative regulation of cellular biosynthetic processGO:00313272770.019
epidermal growth factor receptor signaling pathwayGO:0007173580.019
actin filament based processGO:00300292200.018
purine ribonucleoside metabolic processGO:00461281270.018
oocyte constructionGO:00073081120.018
Fly
positive regulation of reproductive processGO:200024370.018
dendrite morphogenesisGO:00488131990.018
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.018
Fly
nucleoside triphosphate catabolic processGO:00091431080.018
regulation of phosphate metabolic processGO:00192202100.018
digestive system developmentGO:00551231490.018
regulation of cell cycle g1 s phase transitionGO:1902806230.018
Human Fly
regulation of cell morphogenesisGO:00226041630.018
negative regulation of cell cycleGO:00457861160.018
Fly
ribonucleoside catabolic processGO:00424541120.018
covalent chromatin modificationGO:00165691060.017
positive regulation of cell differentiationGO:0045597640.017
cellular carbohydrate metabolic processGO:0044262220.017
regulation of multicellular organismal developmentGO:20000264140.017
Worm
maternal determination of anterior posterior axis embryoGO:0008358740.017
Fly
posttranscriptional gene silencing by rnaGO:0035194450.017
peptidyl amino acid modificationGO:00181931050.017
regulation of protein localizationGO:0032880760.017
chromosome segregationGO:00070591570.017
reactive oxygen species metabolic processGO:0072593220.017
organophosphate catabolic processGO:00464341120.017
response to other organismGO:00517072930.017
positive regulation of catalytic activityGO:00430851180.017
regulation of phosphorylationGO:00423251470.017
organic acid metabolic processGO:00060821030.016
regulation of gene expression epigeneticGO:00400291280.016
actin cytoskeleton organizationGO:00300362060.016
regulation of intracellular transportGO:0032386640.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.016
muscle organ developmentGO:00075171270.015
learning or memoryGO:00076111410.015
organonitrogen compound biosynthetic processGO:19015661170.015
response to nitrogen compoundGO:1901698900.015
histone modificationGO:00165701060.015
centrosome organizationGO:00512971630.015
regulation of cellular ketone metabolic processGO:001056530.015
growthGO:00400073590.015
negative regulation of growthGO:0045926840.015
positive regulation of cellular catabolic processGO:0031331950.015
positive regulation of transcription dna templatedGO:00458932660.015
cell migrationGO:00164772380.015
positive regulation of signal transductionGO:00099672230.015
cell motilityGO:00488702510.015
positive regulation of cellular protein metabolic processGO:00322701180.015
nucleocytoplasmic transportGO:0006913720.015
negative regulation of cellular metabolic processGO:00313243820.015
developmental programmed cell deathGO:00106231380.014
modification dependent macromolecule catabolic processGO:0043632790.014
amine metabolic processGO:0009308120.014
mrna splicing via spliceosomeGO:0000398730.014
pigment metabolic processGO:0042440840.014
cellular protein localizationGO:00346131600.014
regulation of transportGO:00510491810.014
negative regulation of cell proliferationGO:0008285690.014
protein phosphorylationGO:00064681690.014
sister chromatid segregationGO:0000819920.014
regulation of intracellular signal transductionGO:19025312360.014
positive regulation of phosphorylationGO:0042327870.014
response to radiationGO:00093141550.014
rna transportGO:0050658460.014
sensory organ morphogenesisGO:00905962600.014
carboxylic acid metabolic processGO:0019752920.014
dna packagingGO:0006323910.013
oocyte anterior posterior axis specificationGO:0007314720.013
Fly
cell cell signaling involved in cell fate commitmentGO:00451682100.013
defense response to other organismGO:00985422250.013
negative regulation of mitotic cell cycleGO:00459301090.013
Fly
muscle cell differentiationGO:00426921030.013
organelle assemblyGO:00709251980.013
negative regulation of response to stimulusGO:00485852580.013
intracellular mrna localizationGO:0008298660.013
establishment of rna localizationGO:0051236470.013
organophosphate biosynthetic processGO:0090407460.013
positive regulation of mapk cascadeGO:0043410630.013
regulation of ras protein signal transductionGO:0046578930.013
transmembrane transportGO:00550851390.013
purine ribonucleotide catabolic processGO:00091541090.013
eye morphogenesisGO:00485922600.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
dna biosynthetic processGO:0071897240.012
regulation of transferase activityGO:0051338580.012
regulation of proteolysisGO:0030162870.012
nucleoside catabolic processGO:00091641120.012
cellular macromolecular complex assemblyGO:00346221530.012
spindle elongationGO:0051231830.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
macromolecule methylationGO:0043414450.012
defense response to bacteriumGO:00427421780.012
cellular lipid metabolic processGO:0044255830.012
tripartite regional subdivisionGO:00073511030.012
Fly
negative regulation of translationGO:0017148280.012
forebrain developmentGO:003090020.012
Mouse
negative regulation of cell deathGO:0060548810.011
Fly
carbohydrate metabolic processGO:0005975820.011
regulation of cellular component sizeGO:0032535980.011
regulation of protein catabolic processGO:0042176550.011
response to alcoholGO:0097305950.011
positive regulation of multicellular organismal processGO:00512401430.011
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.011
negative regulation of protein metabolic processGO:0051248850.011
regulation of cell divisionGO:0051302720.011
neurological system processGO:00508773580.011
regulation of embryonic developmentGO:0045995680.011
glycosyl compound catabolic processGO:19016581120.011
compound eye developmentGO:00487493070.011
peptidyl lysine modificationGO:0018205570.011
regulation of hydrolase activityGO:0051336970.011
protein processingGO:0016485680.011
g protein coupled receptor signaling pathwayGO:00071861360.011
posttranscriptional gene silencingGO:0016441460.011
regulation of protein modification processGO:00313991120.011
positive regulation of cellular component organizationGO:00511301560.010
lipopolysaccharide mediated signaling pathwayGO:003166310.010
regulation of developmental growthGO:00486381740.010
regulation of immune system processGO:00026821760.010
protein maturationGO:0051604710.010
positive regulation of immune system processGO:0002684680.010
chromatin organizationGO:00063252070.010
atp metabolic processGO:0046034490.010
response to heatGO:0009408630.010
camera type eye developmentGO:004301040.010
larval developmentGO:00021641040.010
Worm
lateral inhibitionGO:00463312060.010
regulation of synapse structure and activityGO:00508031280.010
circadian behaviorGO:0048512760.010
response to woundingGO:0009611940.010
negative regulation of biosynthetic processGO:00098902770.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
protein dna complex subunit organizationGO:0071824860.010

E2f disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org