Drosophila melanogaster

234 known processes

Iswi (Dmel_CG8625)

Imitation SWI

(Aliases: ISWI,SWI,dNURF,ACF,anon-EP1279744.124,Dmel\CG8625,dCHRAC,ISW,dISWI,p140/ISWI,NURF,CHRAC,p140,Nurf-140,NURF-140,iswi,CG8625)

Iswi biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of gene expressionGO:00106293871.000
negative regulation of macromolecule biosynthetic processGO:00105582700.999
nucleosome mobilizationGO:004276690.999
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.999
negative regulation of rna metabolic processGO:00512532510.999
negative regulation of cellular biosynthetic processGO:00313272770.998
negative regulation of cellular metabolic processGO:00313243820.998
chromosome organizationGO:00512763600.995
negative regulation of rna biosynthetic processGO:19026792400.994
negative regulation of mitotic cell cycle phase transitionGO:19019911030.989
negative regulation of transcription dna templatedGO:00458922370.988
negative regulation of nucleobase containing compound metabolic processGO:00459342610.985
negative regulation of nitrogen compound metabolic processGO:00511722650.977
chromatin organizationGO:00063252070.961
nuclear divisionGO:00002803320.959
negative regulation of biosynthetic processGO:00098902770.946
regulation of chromosome organizationGO:0033044640.945
Yeast
mitotic g2 m transition checkpointGO:0044818700.945
chromatin silencingGO:0006342760.933
Yeast Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072400.930
mitotic cell cycle phase transitionGO:00447721380.922
dna damage checkpointGO:0000077780.918
cell cycle phase transitionGO:00447701400.916
regulation of gene expression epigeneticGO:00400291280.908
Yeast Mouse Worm
regulation of cell cycle phase transitionGO:19019871300.895
negative regulation of chromosome segregationGO:0051985140.886
negative regulation of cell cycle phase transitionGO:19019881030.877
dna integrity checkpointGO:0031570810.848
meiotic cell cycleGO:00513211710.846
mitotic g2 dna damage checkpointGO:0007095690.830
cell cycle checkpointGO:0000075950.811
stem cell maintenanceGO:0019827670.806
meiotic cell cycle processGO:19030461320.804
g2 dna damage checkpointGO:0031572690.799
regulation of cell cycle processGO:00105641810.788
embryo development ending in birth or egg hatchingGO:00097921520.783
Worm
regulation of cell cycleGO:00517262910.780
histone modificationGO:00165701060.777
negative regulation of mitotic cell cycleGO:00459301090.775
cellular response to dna damage stimulusGO:00069742230.766
Mouse
mitotic dna damage checkpointGO:0044773740.758
regulation of mitotic cell cycle phase transitionGO:19019901300.746
regulation of mitotic sister chromatid segregationGO:0033047280.742
covalent chromatin modificationGO:00165691060.737
mitotic cell cycle checkpointGO:0007093880.723
meiotic chromosome segregationGO:0045132590.699
dna conformation changeGO:00711031050.672
chromosome segregationGO:00070591570.670
mitotic sister chromatid separationGO:0051306300.666
meiotic nuclear divisionGO:00071261510.649
rhythmic processGO:00485111060.639
regulation of mitotic cell cycleGO:00073461900.625
cell proliferationGO:00082832990.604
Mouse
cell deathGO:00082192790.582
regulation of metaphase anaphase transition of cell cycleGO:1902099260.563
circadian rhythmGO:00076231050.532
positive regulation of nitrogen compound metabolic processGO:00511733540.516
regulation of mitosisGO:0007088560.511
negative regulation of chromosome organizationGO:2001251190.505
Yeast
regulation of mitotic metaphase anaphase transitionGO:0030071260.501
dna packagingGO:0006323910.498
chromatin modificationGO:00165681470.488
mitotic dna integrity checkpointGO:0044774750.478
regulation of cellular catabolic processGO:00313291570.455
sister chromatid segregationGO:0000819920.453
mitotic spindle assembly checkpointGO:0007094110.451
compound eye morphogenesisGO:00017452490.445
negative regulation of cell cycle processGO:00109481090.419
negative regulation of cell cycleGO:00457861160.402
mitotic nuclear divisionGO:00070672130.400
chromosome separationGO:0051304420.396
maintenance of protein location in cellGO:0032507260.375
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.360
atp metabolic processGO:0046034490.346
regulation of cell differentiationGO:00455953020.343
determination of adult lifespanGO:00083401370.339
Worm
chromatin assembly or disassemblyGO:0006333520.337
cell divisionGO:00513012480.332
metaphase anaphase transition of cell cycleGO:0044784280.332
regulation of proteasomal protein catabolic processGO:0061136390.315
nucleobase containing compound catabolic processGO:00346551650.304
regulation of cell divisionGO:0051302720.304
protein modification by small protein conjugation or removalGO:00706471060.298
regulation of nuclear divisionGO:0051783580.298
catabolic processGO:00090564090.295
negative regulation of sister chromatid segregationGO:0033046130.293
organelle fissionGO:00482853400.286
regulation of meiosisGO:004002030.279
gene silencingGO:00164581380.271
Yeast Mouse Worm
metaphase plate congressionGO:0051310190.266
negative regulation of mitotic sister chromatid separationGO:2000816130.260
immune system processGO:00023763470.243
programmed cell deathGO:00125012570.241
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.237
intracellular steroid hormone receptor signaling pathwayGO:0030518120.225
cellular catabolic processGO:00442483720.224
negative regulation of cellular protein metabolic processGO:0032269850.224
organelle assemblyGO:00709251980.216
peptidyl amino acid modificationGO:00181931050.215
regulation of circadian rhythmGO:0042752490.212
positive regulation of macromolecule metabolic processGO:00106044050.212
cellular protein catabolic processGO:0044257830.211
regulation of sister chromatid segregationGO:0033045280.208
compound eye developmentGO:00487493070.206
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.204
regulation of protein catabolic processGO:0042176550.202
mitotic sister chromatid segregationGO:0000070870.198
metaphase anaphase transition of mitotic cell cycleGO:0007091280.195
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.193
regulation of rna splicingGO:0043484690.190
cellular macromolecule catabolic processGO:00442651360.180
cellular protein localizationGO:00346131600.178
positive regulation of signal transductionGO:00099672230.178
spermatid differentiationGO:00485151140.178
positive regulation of cell proliferationGO:0008284470.177
regulation of cellular protein metabolic processGO:00322682430.165
signal transduction in response to dna damageGO:004277030.163
nucleoside metabolic processGO:00091161270.162
proteasomal protein catabolic processGO:0010498590.160
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.159
eye developmentGO:00016543230.157
Zebrafish
negative regulation of gene expression epigeneticGO:0045814770.154
Yeast Mouse
immune responseGO:00069552460.153
gene silencing by rnaGO:0031047570.153
Worm
multicellular organismal agingGO:00102591400.151
Worm
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.145
organic substance catabolic processGO:19015753080.143
posttranscriptional gene silencingGO:0016441460.141
Worm
eye morphogenesisGO:00485922600.141
development of primary sexual characteristicsGO:0045137500.140
Worm
regulation of proteolysisGO:0030162870.139
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.139
protein modification by small protein conjugationGO:0032446790.135
regulation of defense responseGO:00313471020.132
negative regulation of developmental processGO:00510932010.129
Worm
positive regulation of rna metabolic processGO:00512542710.129
regulation of multi organism processGO:00439001310.129
rna splicingGO:0008380830.128
response to heatGO:0009408630.128
gonad developmentGO:0008406500.126
Worm
regulation of chromatin modificationGO:1903308280.126
Yeast
regulation of cell deathGO:00109411730.122
mitotic spindle organizationGO:00070522200.121
regulation of cellular protein catabolic processGO:1903362440.118
response to lipidGO:0033993380.118
stem cell developmentGO:0048864790.116
larval developmentGO:00021641040.112
Worm
transcription from rna polymerase ii promoterGO:00063663680.112
regulation of programmed cell deathGO:00430671520.112
proteolysis involved in cellular protein catabolic processGO:0051603830.111
chromosome condensationGO:0030261410.110
purine ribonucleoside monophosphate metabolic processGO:0009167500.108
protein ubiquitinationGO:0016567700.108
heterochromatin organizationGO:0070828250.108
Yeast
positive regulation of rna biosynthetic processGO:19026802660.106
regulation of mitotic sister chromatid separationGO:0010965280.105
protein modification processGO:00362114380.105
apoptotic processGO:00069151590.104
peptidyl lysine methylationGO:0018022160.101
positive regulation of transcription dna templatedGO:00458932660.098
negative regulation of protein metabolic processGO:0051248850.097
chromatin remodelingGO:0006338720.096
oocyte differentiationGO:00099941450.096
atp catabolic processGO:0006200380.095
regulation of protein metabolic processGO:00512462560.095
response to organic cyclic compoundGO:0014070890.094
modification dependent macromolecule catabolic processGO:0043632790.094
response to sterolGO:0036314340.094
purine nucleoside metabolic processGO:00422781270.092
positive regulation of cell communicationGO:00106472500.090
organic substance transportGO:00717022570.089
heterocycle catabolic processGO:00467001660.088
hematopoietic or lymphoid organ developmentGO:0048534570.085
regulation of heterochromatin assemblyGO:003144580.084
positive regulation of cellular biosynthetic processGO:00313283160.083
histone acetylationGO:0016573380.082
regulation of molecular functionGO:00650092170.081
regulation of dna metabolic processGO:0051052340.081
regulation of mrna splicing via spliceosomeGO:0048024640.081
post embryonic appendage morphogenesisGO:00351203850.080
rna processingGO:00063961470.077
body morphogenesisGO:001017120.077
rna interferenceGO:0016246270.076
Worm
intracellular receptor signaling pathwayGO:0030522190.076
spindle assembly checkpointGO:0071173110.075
organonitrogen compound catabolic processGO:19015651280.075
nucleoside monophosphate metabolic processGO:0009123520.071
response to abiotic stimulusGO:00096283410.071
nucleoside triphosphate metabolic processGO:00091411200.070
deathGO:00162652840.069
innate immune responseGO:00450871440.068
nucleotide catabolic processGO:00091661090.067
purine nucleoside catabolic processGO:00061521120.067
negative regulation of cell divisionGO:0051782170.066
positive regulation of nucleobase containing compound metabolic processGO:00459353320.065
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.065
cellular nitrogen compound catabolic processGO:00442701650.064
organic cyclic compound catabolic processGO:19013611680.064
positive regulation of developmental growthGO:0048639620.064
regulation of meiotic cell cycleGO:005144590.064
germarium derived female germ line cyst formationGO:0030727420.064
ribonucleotide metabolic processGO:00092591450.063
regulation of cellular localizationGO:00603411360.062
negative regulation of cell differentiationGO:00455961430.062
ribonucleoside triphosphate catabolic processGO:00092031080.060
negative regulation of mitotic sister chromatid segregationGO:0033048130.059
germ line stem cell maintenanceGO:0030718500.059
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.058
Yeast
ribonucleoside metabolic processGO:00091191270.057
agingGO:00075681430.056
Worm
negative regulation of proteasomal protein catabolic processGO:1901799160.055
response to radiationGO:00093141550.055
nucleoside monophosphate catabolic processGO:0009125390.052
mrna metabolic processGO:00160711240.052
female meiotic divisionGO:0007143700.052
mrna processingGO:00063971040.050
macromolecule catabolic processGO:00090571610.050
modification dependent protein catabolic processGO:0019941780.050
multi organism behaviorGO:00517051750.050
cellular protein modification processGO:00064644380.049
positive regulation of biosynthetic processGO:00098913160.049
ribonucleoside monophosphate catabolic processGO:0009158390.049
peptidyl lysine modificationGO:0018205570.048
regulation of gene silencingGO:0060968630.048
ubiquitin dependent protein catabolic processGO:0006511780.047
organonitrogen compound metabolic processGO:19015643180.047
cellular macromolecule localizationGO:00707272200.047
nucleotide metabolic processGO:00091171610.047
regulation of organelle organizationGO:00330431960.047
Yeast
response to organic substanceGO:00100332840.046
glycosyl compound catabolic processGO:19016581120.046
female germ line cyst formationGO:0048135420.046
notch signaling pathwayGO:00072191200.045
glycosyl compound metabolic processGO:19016571270.045
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.042
spermatogenesisGO:00072832000.042
regulation of mrna processingGO:0050684710.041
protein catabolic processGO:00301631010.041
imaginal disc derived appendage developmentGO:00487373990.041
ribose phosphate metabolic processGO:00196931450.040
carbohydrate derivative metabolic processGO:19011352170.039
ribonucleoside triphosphate metabolic processGO:00091991190.039
mrna splicing via spliceosomeGO:0000398730.039
regulation of protein modification processGO:00313991120.039
cellular response to abiotic stimulusGO:0071214580.038
dna repairGO:0006281540.038
Mouse
nucleobase containing small molecule metabolic processGO:00550861740.038
regulation of hemocyte proliferationGO:0035206370.037
maintenance of locationGO:0051235730.037
negative regulation of programmed cell deathGO:0043069720.036
posttranscriptional regulation of gene expressionGO:00106081450.036
Worm
positive regulation of cell deathGO:0010942690.035
positive regulation of programmed cell deathGO:0043068620.035
posttranscriptional gene silencing by rnaGO:0035194450.035
Worm
regulation of sister chromatid cohesionGO:000706320.035
regulation of response to stressGO:00801342000.035
purine nucleoside triphosphate metabolic processGO:00091441190.033
single organism catabolic processGO:00447122280.033
negative regulation of protein catabolic processGO:0042177170.033
intracellular signal transductionGO:00355563000.033
positive regulation of nucleocytoplasmic transportGO:0046824240.032
compound eye photoreceptor cell differentiationGO:00017511400.031
peptidyl lysine trimethylationGO:001802360.031
stem cell differentiationGO:00488631170.031
regulation of establishment of protein localizationGO:0070201610.031
spindle organizationGO:00070512530.030
nuclear body organizationGO:003057560.030
nucleosome organizationGO:0034728590.030
intracellular protein transportGO:00068861040.029
positive regulation of apoptotic processGO:0043065470.028
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.028
organophosphate metabolic processGO:00196371950.028
positive regulation of mitotic sister chromatid separationGO:1901970100.027
regulation of cell proliferationGO:00421271630.027
Mouse
purine nucleoside monophosphate metabolic processGO:0009126500.027
tube morphogenesisGO:00352391910.027
cellular amino acid metabolic processGO:0006520610.027
negative regulation of neuroblast proliferationGO:0007406270.027
purine containing compound metabolic processGO:00725211550.027
eye photoreceptor cell differentiationGO:00017541450.026
positive regulation of chromatin silencingGO:0031937160.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of apoptotic processGO:00429811300.025
protein transportGO:00150311550.024
protein localization to organelleGO:0033365820.024
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.023
purine nucleoside triphosphate catabolic processGO:00091461080.023
regulation of immune system processGO:00026821760.023
positive regulation of protein modification processGO:0031401580.023
regulation of innate immune responseGO:0045088710.022
male gamete generationGO:00482322010.022
circulatory system developmentGO:0072359820.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
purine ribonucleoside monophosphate catabolic processGO:0009169380.022
production of mirnas involved in gene silencing by mirnaGO:0035196100.022
regulation of intracellular signal transductionGO:19025312360.022
reproductive system developmentGO:0061458740.022
Worm
negative regulation of neurotransmitter secretionGO:004692920.022
embryonic development via the syncytial blastodermGO:00017001480.022
regulation of chromatin organizationGO:1902275320.022
Yeast
histone methylationGO:0016571400.021
macromolecular complex assemblyGO:00650032560.021
regulation of protein processingGO:0070613320.021
single organism nuclear importGO:1902593510.021
digestive tract developmentGO:00485651490.021
positive regulation of signalingGO:00230562430.021
ribonucleotide catabolic processGO:00092611090.020
histone h4 k20 methylationGO:003477040.020
negative regulation of cellular protein catabolic processGO:1903363170.020
regulation of protein localizationGO:0032880760.020
muscle structure developmentGO:00610612240.020
immune system developmentGO:0002520570.020
positive regulation of transcription from rna polymerase i promoterGO:004594330.020
histone h3 k4 methylationGO:0051568160.019
hemopoiesisGO:0030097460.019
negative regulation of organelle organizationGO:0010639560.019
Yeast
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
cellular macromolecular complex assemblyGO:00346221530.019
positive regulation of proteolysisGO:0045862520.019
nucleoside triphosphate catabolic processGO:00091431080.019
positive regulation of molecular functionGO:00440931360.019
regulation of postsynaptic membrane potentialGO:006007850.018
regulation of chromatin assemblyGO:001084790.018
meiosis iGO:0007127590.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
phagocytosisGO:00069092150.018
purine ribonucleoside metabolic processGO:00461281270.018
negative regulation of molecular functionGO:0044092510.018
ribonucleoside catabolic processGO:00424541120.018
regulation of response to dna damage stimulusGO:2001020230.018
methylationGO:0032259470.018
regulation of phosphate metabolic processGO:00192202100.018
neuron projection guidanceGO:00974852410.018
axonogenesisGO:00074092900.018
digestive system developmentGO:00551231490.018
cellular response to ketoneGO:1901655170.017
regulation of mrna metabolic processGO:1903311720.017
sensory organ morphogenesisGO:00905962600.017
negative regulation of nucleotide metabolic processGO:004598040.017
purine containing compound catabolic processGO:00725231120.017
microtubule cytoskeleton organization involved in mitosisGO:1902850520.017
jak stat cascadeGO:0007259490.017
protein targeting to nucleusGO:0044744510.017
negative regulation of proteolysisGO:0045861310.017
internal peptidyl lysine acetylationGO:0018393380.017
protein processingGO:0016485680.016
positive regulation of proteasomal protein catabolic processGO:1901800200.016
positive regulation of developmental processGO:00510941430.016
Worm
nucleoside phosphate metabolic processGO:00067531620.016
purine ribonucleoside catabolic processGO:00461301120.016
germ line cyst formationGO:0048134440.016
maintenance of location in cellGO:0051651280.016
dna metabolic processGO:00062592270.016
regulation of chromatin silencingGO:0031935360.016
positive regulation of erk1 and erk2 cascadeGO:0070374360.015
protein localization to nucleusGO:0034504550.015
small molecule metabolic processGO:00442813050.015
genitalia developmentGO:0048806260.015
Worm
ecdysone receptor mediated signaling pathwayGO:0035076110.015
protein localizationGO:00081042840.015
negative regulation of cell deathGO:0060548810.015
ribonucleoprotein complex biogenesisGO:0022613310.015
regulation of cellular amine metabolic processGO:003323830.015
regulation of chromosome segregationGO:0051983320.015
nucleus organizationGO:0006997450.015
nitric oxide metabolic processGO:004620910.014
response to light stimulusGO:00094161240.014
negative regulation of cellular catabolic processGO:0031330340.014
purine nucleoside monophosphate catabolic processGO:0009128380.014
regulation of immune responseGO:00507761180.014
establishment of protein localizationGO:00451841630.014
negative regulation of nucleoside metabolic processGO:004597810.014
germarium derived oocyte differentiationGO:0030706290.014
actin filament based processGO:00300292200.014
circadian behaviorGO:0048512760.014
negative regulation of protein maturationGO:1903318310.014
phosphorylationGO:00163102940.013
appendage morphogenesisGO:00351073970.013
negative regulation of protein processingGO:0010955310.013
negative regulation of mitosisGO:0045839160.013
proteolysisGO:00065081920.013
positive regulation of growthGO:0045927750.013
nuclear importGO:0051170510.013
axon developmentGO:00615642970.013
positive regulation of cellular protein metabolic processGO:00322701180.013
peptidyl lysine acetylationGO:0018394390.012
negative regulation of multicellular organismal processGO:00512411420.012
Worm
histone h2a acetylationGO:004396810.012
purine nucleotide metabolic processGO:00061631460.012
organelle inheritanceGO:004830820.012
asymmetric neuroblast division resulting in ganglion mother cell formationGO:005506020.012
nucleosome positioningGO:001658430.012
negative regulation of defense responseGO:0031348350.012
ovipositionGO:0018991190.012
wing disc morphogenesisGO:00074723440.012
regulation of neuron deathGO:1901214260.011
negative regulation of neural precursor cell proliferationGO:2000178270.011
positive regulation of apoptotic signaling pathwayGO:200123540.011
heart developmentGO:0007507820.011
aromatic compound catabolic processGO:00194391660.011
locomotory behaviorGO:00076261760.011
protein alkylationGO:0008213430.011
cell migrationGO:00164772380.011
antimicrobial humoral responseGO:0019730990.011
reproductive structure developmentGO:0048608740.010
Worm
mrna splice site selectionGO:000637610.010
humoral immune responseGO:00069591170.010
sex differentiationGO:0007548810.010
Worm
lipid storageGO:0019915380.010
protein maturationGO:0051604710.010
regionalizationGO:00030024160.010
regulation of notch signaling pathwayGO:00085931000.010
regulation of cell shapeGO:00083601130.010

Iswi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
chromosomal diseaseDOID:008001400.021
gonadal dysgenesisDOID:1444700.021
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011