IMP: Integrative Multi-species Prediction

Drosophila melanogaster

136 known processes

eff (Dmel_CG7425)

effete

(Aliases: ms(3)88D,fs(3)01295,ms(3)ry1,l(3)j2C8,ms(3)ry3,6535,Dmel\CG7425,ubcD1,Eff,E(Pc)88D,anon-WO0118547.343,ms(3)neo2,mei68,Ubc-D1,ms(3)01295,UbcD1,Mei-W68,l(3)s1782,3527,l(3)01462,UBCD-1,ms(3)3,ms(3)1,UbcD,CG7425,SS3-3,UBC4,UBCD1)

FLYBASE: FBgn0011217
Entrez: 41785
UniProtKB: P25867

Process Predictions
Disease Predictions

eff biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cell differentiation	GO:0045595	302	0.986
stem cell differentiation	GO:0048863	117	0.957
male gamete generation	GO:0048232	201	0.933
negative regulation of developmental process	GO:0051093	201	0.895
spermatogenesis	GO:0007283	200	0.893
stem cell maintenance	GO:0019827	67	0.891
negative regulation of cell differentiation	GO:0045596	143	0.881
death	GO:0016265	284	0.880	Worm
dendrite development	GO:0016358	204	0.854
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.841
positive regulation of macromolecule metabolic process	GO:0010604	405	0.820
sensory organ morphogenesis	GO:0090596	260	0.819
negative regulation of gene expression	GO:0010629	387	0.813
regulation of transport	GO:0051049	181	0.805
establishment of localization in cell	GO:0051649	402	0.803
regulation of cellular protein metabolic process	GO:0032268	243	0.777
cellular protein modification process	GO:0006464	438	0.763
regulation of localization	GO:0032879	275	0.721
eye morphogenesis	GO:0048592	260	0.712
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.702
protein modification by small protein conjugation or removal	GO:0070647	106	0.661
meiotic cell cycle	GO:0051321	171	0.651
fusome organization	GO:0045478	13	0.632
brain development	GO:0007420	120	0.623
spermatid development	GO:0007286	98	0.615
positive regulation of biosynthetic process	GO:0009891	316	0.601
transcription from rna polymerase ii promoter	GO:0006366	368	0.600
protein localization	GO:0008104	284	0.598
response to abiotic stimulus	GO:0009628	341	0.585	Yeast
germ line stem cell maintenance	GO:0030718	50	0.559
meiotic cell cycle process	GO:1903046	132	0.553
mushroom body development	GO:0016319	70	0.545
mitotic cell cycle phase transition	GO:0044772	138	0.545
female germ line stem cell asymmetric division	GO:0048132	14	0.535
protein modification by small protein conjugation	GO:0032446	79	0.534
negative regulation of cell cycle phase transition	GO:1901988	103	0.524
eye development	GO:0001654	323	0.510
positive regulation of transcription dna templated	GO:0045893	266	0.506
central nervous system development	GO:0007417	201	0.500
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.487
ovarian fusome organization	GO:0030723	11	0.482
negative regulation of transcription dna templated	GO:0045892	237	0.470
response to bacterium	GO:0009617	198	0.462
endomembrane system organization	GO:0010256	119	0.461
spermatocyte division	GO:0048137	13	0.458
actin cytoskeleton organization	GO:0030036	206	0.457
posttranscriptional regulation of gene expression	GO:0010608	145	0.454
regulation of multicellular organismal development	GO:2000026	414	0.447
cell death	GO:0008219	279	0.442	Worm
positive regulation of protein metabolic process	GO:0051247	128	0.433
meiotic nuclear division	GO:0007126	151	0.426
actin filament based process	GO:0030029	220	0.423
protein modification process	GO:0036211	438	0.419
cytoplasmic transport	GO:0016482	130	0.419
germline stem cell asymmetric division	GO:0098728	15	0.411
cellular macromolecule localization	GO:0070727	220	0.408
organophosphate metabolic process	GO:0019637	195	0.397
muscle cell differentiation	GO:0042692	103	0.396
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.389
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.378
stem cell division	GO:0017145	69	0.376
negative regulation of multicellular organismal process	GO:0051241	142	0.376
regulation of neurogenesis	GO:0050767	158	0.373
protein targeting to nucleus	GO:0044744	51	0.367
cellular protein catabolic process	GO:0044257	83	0.364
chromatin organization	GO:0006325	207	0.353
chromatin silencing	GO:0006342	76	0.347
embryo development ending in birth or egg hatching	GO:0009792	152	0.335	Worm
macromolecule catabolic process	GO:0009057	161	0.332
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.324
neuron projection guidance	GO:0097485	241	0.320
positive regulation of rna metabolic process	GO:0051254	271	0.317
larval development	GO:0002164	104	0.310	Worm
pronuclear migration	GO:0035046	4	0.307
response to toxic substance	GO:0009636	22	0.305
regulation of cell shape	GO:0008360	113	0.304
single organism cellular localization	GO:1902580	180	0.303
mitochondrion morphogenesis	GO:0070584	8	0.300
axon guidance	GO:0007411	233	0.284
centrosome cycle	GO:0007098	137	0.284
regulation of nervous system development	GO:0051960	248	0.284
compound eye development	GO:0048749	307	0.283
response to biotic stimulus	GO:0009607	294	0.283
endocytosis	GO:0006897	310	0.282	Worm
purine nucleoside metabolic process	GO:0042278	127	0.280
positive regulation of gene expression	GO:0010628	290	0.279
cellular protein localization	GO:0034613	160	0.276
negative regulation of nervous system development	GO:0051961	92	0.273
intracellular protein transmembrane import	GO:0044743	4	0.271
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.266
compound eye photoreceptor cell differentiation	GO:0001751	140	0.266
axon development	GO:0061564	297	0.262
actin filament organization	GO:0007015	126	0.259
multicellular organismal aging	GO:0010259	140	0.259
membrane disassembly	GO:0030397	4	0.258
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.254
stem cell development	GO:0048864	79	0.249
nucleus organization	GO:0006997	45	0.248
transmembrane transport	GO:0055085	139	0.246
positive regulation of cellular protein metabolic process	GO:0032270	118	0.246
positive regulation of cellular biosynthetic process	GO:0031328	316	0.239
purine nucleotide metabolic process	GO:0006163	146	0.238
response to external biotic stimulus	GO:0043207	293	0.234
embryonic organ development	GO:0048568	50	0.227
organic substance transport	GO:0071702	257	0.224
regulation of protein metabolic process	GO:0051246	256	0.223
single organism membrane organization	GO:0044802	93	0.221
negative regulation of cell cycle process	GO:0010948	109	0.214
establishment of organelle localization	GO:0051656	122	0.213
heart morphogenesis	GO:0003007	32	0.211
spermatid differentiation	GO:0048515	114	0.210
eye photoreceptor cell differentiation	GO:0001754	145	0.203
macromolecular complex assembly	GO:0065003	256	0.202
spindle organization	GO:0007051	253	0.201
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.200
cell maturation	GO:0048469	144	0.196
germ line stem cell division	GO:0042078	25	0.193
ubiquitin dependent protein catabolic process	GO:0006511	78	0.192
positive regulation of rna biosynthetic process	GO:1902680	266	0.190
chromatin modification	GO:0016568	147	0.187
meiotic cytokinesis	GO:0033206	33	0.187
regulation of cellular component biogenesis	GO:0044087	201	0.186
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.183
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.182
regulation of molecular function	GO:0065009	217	0.178
regulation of cellular catabolic process	GO:0031329	157	0.177
aging	GO:0007568	143	0.172
mitotic nuclear division	GO:0007067	213	0.168
organelle fission	GO:0048285	340	0.165
head development	GO:0060322	135	0.160
positive regulation of molecular function	GO:0044093	136	0.159
ribonucleotide metabolic process	GO:0009259	145	0.154
male meiosis cytokinesis	GO:0007112	26	0.153
purine ribonucleotide catabolic process	GO:0009154	109	0.149
single organism intracellular transport	GO:1902582	207	0.148
centrosome duplication	GO:0051298	121	0.148
oocyte differentiation	GO:0009994	145	0.146
germarium derived female germ line cyst formation	GO:0030727	42	0.146
protein import	GO:0017038	55	0.143
chromosome organization	GO:0051276	360	0.142
stem cell proliferation	GO:0072089	88	0.139
growth	GO:0040007	359	0.137
chemotaxis	GO:0006935	249	0.136
response to radiation	GO:0009314	155	0.133
axonogenesis	GO:0007409	290	0.132
establishment of spindle orientation	GO:0051294	18	0.131
vesicle mediated transport	GO:0016192	381	0.130	Worm
establishment of protein localization to organelle	GO:0072594	62	0.129
intracellular protein transport	GO:0006886	104	0.127
nucleotide metabolic process	GO:0009117	161	0.127
cognition	GO:0050890	141	0.127
regulation of gene expression epigenetic	GO:0040029	128	0.126
cell motility	GO:0048870	251	0.122	Worm
cellular protein complex assembly	GO:0043623	71	0.121
nucleoside metabolic process	GO:0009116	127	0.120
muscle cell development	GO:0055001	50	0.120
meiotic spindle organization	GO:0000212	36	0.120
developmental programmed cell death	GO:0010623	138	0.119
ion transport	GO:0006811	145	0.118
photoreceptor cell differentiation	GO:0046530	170	0.117
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0030722	6	0.114
organic cyclic compound catabolic process	GO:1901361	168	0.113
single fertilization	GO:0007338	24	0.113
cellular catabolic process	GO:0044248	372	0.113
protein catabolic process	GO:0030163	101	0.110
protein ubiquitination	GO:0016567	70	0.109
protein localization to organelle	GO:0033365	82	0.108
glial cell differentiation	GO:0010001	35	0.108
nuclear division	GO:0000280	332	0.107
defense response to bacterium	GO:0042742	178	0.105
establishment of spindle localization	GO:0051293	22	0.105
forebrain development	GO:0030900	2	0.105
membrane organization	GO:0061024	112	0.104
response to oxygen containing compound	GO:1901700	200	0.104
neurological system process	GO:0050877	358	0.103
germ line cyst formation	GO:0048134	44	0.102
intracellular transport	GO:0046907	228	0.099
ribonucleotide catabolic process	GO:0009261	109	0.099
muscle structure development	GO:0061061	224	0.099
purine ribonucleoside metabolic process	GO:0046128	127	0.098
negative regulation of mitotic cell cycle	GO:0045930	109	0.098
organelle localization	GO:0051640	148	0.097
organic substance catabolic process	GO:1901575	308	0.096
cell cycle phase transition	GO:0044770	140	0.096
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.096
embryonic development via the syncytial blastoderm	GO:0001700	148	0.095
protein transmembrane transport	GO:0071806	4	0.095
regulation of protein modification process	GO:0031399	112	0.094
regulation of nucleocytoplasmic transport	GO:0046822	35	0.094
cellular response to chemical stimulus	GO:0070887	199	0.092
negative regulation of cell proliferation	GO:0008285	69	0.092
nucleobase containing small molecule metabolic process	GO:0055086	174	0.092
kidney morphogenesis	GO:0060993	3	0.092
regulation of imaginal disc derived wing size	GO:0044719	20	0.091
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.090
nucleoside phosphate metabolic process	GO:0006753	162	0.088
positive regulation of neurogenesis	GO:0050769	41	0.088
histone modification	GO:0016570	106	0.086
microtubule organizing center organization	GO:0031023	168	0.085
wing disc morphogenesis	GO:0007472	344	0.084
regulation of cytoskeleton organization	GO:0051493	89	0.084
cell adhesion	GO:0007155	136	0.083
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.083
rna localization	GO:0006403	115	0.083
body morphogenesis	GO:0010171	2	0.082
establishment of protein localization	GO:0045184	163	0.082
positive regulation of cell death	GO:0010942	69	0.078
regulation of cell cycle phase transition	GO:1901987	130	0.078
determination of adult lifespan	GO:0008340	137	0.078
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.077
cardiovascular system development	GO:0072358	82	0.077
purine containing compound metabolic process	GO:0072521	155	0.077
purine containing compound catabolic process	GO:0072523	112	0.077
nucleoside triphosphate metabolic process	GO:0009141	120	0.076
catabolic process	GO:0009056	409	0.075
response to temperature stimulus	GO:0009266	106	0.075	Yeast
germarium derived female germ line cyst encapsulation	GO:0030708	8	0.075
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.074
imaginal disc derived wing morphogenesis	GO:0007476	337	0.074
posttranscriptional gene silencing	GO:0016441	46	0.074
regulation of cell development	GO:0060284	215	0.074
protein import into nucleus	GO:0006606	51	0.073
hemopoiesis	GO:0030097	46	0.073
compound eye photoreceptor development	GO:0042051	78	0.073
negative regulation of cellular biosynthetic process	GO:0031327	277	0.073
regulation of anatomical structure morphogenesis	GO:0022603	242	0.073
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.072
negative regulation of catabolic process	GO:0009895	36	0.072
ion transmembrane transport	GO:0034220	122	0.071
circulatory system process	GO:0003013	37	0.070
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.070
appendage development	GO:0048736	401	0.070
intracellular protein transmembrane transport	GO:0065002	4	0.069
mitotic spindle organization	GO:0007052	220	0.069
cell division	GO:0051301	248	0.069
regulation of vesicle mediated transport	GO:0060627	59	0.069
purine nucleotide catabolic process	GO:0006195	109	0.069
response to organic substance	GO:0010033	284	0.069
response to other organism	GO:0051707	293	0.068
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.068
proteasomal protein catabolic process	GO:0010498	59	0.067
cellular response to dna damage stimulus	GO:0006974	223	0.067
cell migration	GO:0016477	238	0.066	Worm
purine ribonucleotide metabolic process	GO:0009150	145	0.065
negative regulation of cell death	GO:0060548	81	0.065
single organism catabolic process	GO:0044712	228	0.065
cellular macromolecular complex assembly	GO:0034622	153	0.064
small molecule metabolic process	GO:0044281	305	0.064
regulation of actin cytoskeleton organization	GO:0032956	42	0.064
positive regulation of programmed cell death	GO:0043068	62	0.064
female germ line cyst formation	GO:0048135	42	0.064
morphogenesis of larval imaginal disc epithelium	GO:0016335	5	0.063
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.063
protein transport	GO:0015031	155	0.062
protein polymerization	GO:0051258	42	0.061
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.061
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.061
organonitrogen compound metabolic process	GO:1901564	318	0.061
regulation of cell morphogenesis	GO:0022604	163	0.061
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.061
protein complex assembly	GO:0006461	200	0.060
centrosome organization	GO:0051297	163	0.059
cell proliferation	GO:0008283	299	0.058
regulation of synapse organization	GO:0050807	110	0.058
single organism biosynthetic process	GO:0044711	206	0.058
neuromuscular junction development	GO:0007528	149	0.058
compound eye morphogenesis	GO:0001745	249	0.057
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.056
dendrite morphogenesis	GO:0048813	199	0.056
taxis	GO:0042330	304	0.055
regulation of organelle organization	GO:0033043	196	0.055
gliogenesis	GO:0042063	80	0.055
respiratory system development	GO:0060541	213	0.054
chromosome segregation	GO:0007059	157	0.054
intracellular mrna localization	GO:0008298	66	0.053
negative regulation of cell cycle	GO:0045786	116	0.053
myofibril assembly	GO:0030239	36	0.053
heart development	GO:0007507	82	0.053
positive regulation of multicellular organismal process	GO:0051240	143	0.052
positive regulation of cell development	GO:0010720	61	0.052
nuclear import	GO:0051170	51	0.052
lateral inhibition	GO:0046331	206	0.052
imaginal disc derived appendage development	GO:0048737	399	0.052
rna interference	GO:0016246	27	0.052
developmental maturation	GO:0021700	172	0.051
cellularization	GO:0007349	90	0.051
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.051
instar larval development	GO:0002168	55	0.050
nucleoside catabolic process	GO:0009164	112	0.050
regulation of translation	GO:0006417	56	0.049
covalent chromatin modification	GO:0016569	106	0.049
modification dependent macromolecule catabolic process	GO:0043632	79	0.049
regulation of actin filament based process	GO:0032970	42	0.049
g2 dna damage checkpoint	GO:0031572	69	0.049
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.048
protein complex biogenesis	GO:0070271	201	0.048
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.048
dorsal ventral axis specification	GO:0009950	66	0.047
epidermis development	GO:0008544	65	0.047
synaptic growth at neuromuscular junction	GO:0051124	119	0.047
regulation of developmental growth	GO:0048638	174	0.047
sperm individualization	GO:0007291	48	0.047
response to organonitrogen compound	GO:0010243	75	0.047
nucleotide catabolic process	GO:0009166	109	0.047
digestive tract morphogenesis	GO:0048546	127	0.047
histolysis	GO:0007559	102	0.047
positive regulation of developmental process	GO:0051094	143	0.046
regulation of cellular protein catabolic process	GO:1903362	44	0.046
photoreceptor cell development	GO:0042461	96	0.046
establishment of mitotic spindle localization	GO:0040001	17	0.046
sex differentiation	GO:0007548	81	0.046	Worm
posttranscriptional gene silencing by rna	GO:0035194	45	0.045
nucleoside triphosphate catabolic process	GO:0009143	108	0.045
glial cell development	GO:0021782	27	0.045
cortical actin cytoskeleton organization	GO:0030866	24	0.045
striated muscle cell development	GO:0055002	50	0.044
single organism nuclear import	GO:1902593	51	0.044
programmed cell death	GO:0012501	257	0.043	Worm
regulation of apoptotic process	GO:0042981	130	0.043
germ line cyst encapsulation	GO:0048138	8	0.043
lipid storage	GO:0019915	38	0.043	Worm
single organism behavior	GO:0044708	391	0.043
ribose phosphate metabolic process	GO:0019693	145	0.042
dorsal closure spreading of leading edge cells	GO:0007395	4	0.042
ribonucleoside catabolic process	GO:0042454	112	0.041
neuron maturation	GO:0042551	31	0.041
camera type eye development	GO:0043010	4	0.041
apoptotic process	GO:0006915	159	0.041	Worm
negative regulation of developmental growth	GO:0048640	64	0.040
nuclear envelope organization	GO:0006998	7	0.040
glycosyl compound metabolic process	GO:1901657	127	0.040
protein adp ribosylation	GO:0006471	4	0.040
limb morphogenesis	GO:0035108	1	0.040
oocyte development	GO:0048599	124	0.040
nephron epithelium morphogenesis	GO:0072088	3	0.040
regulation of cell death	GO:0010941	173	0.040
regulation of neuron projection development	GO:0010975	69	0.040
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.039
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.039
multicellular organismal reproductive behavior	GO:0033057	110	0.038
stem cell fate commitment	GO:0048865	25	0.038
anterior posterior pattern specification	GO:0009952	136	0.038
regulation of protein localization	GO:0032880	76	0.038
early endosome to late endosome transport	GO:0045022	3	0.038
regulation of epithelial cell proliferation	GO:0050678	4	0.038
aromatic compound catabolic process	GO:0019439	166	0.038
tube development	GO:0035295	244	0.038
negative regulation of cell development	GO:0010721	62	0.038
blastoderm segmentation	GO:0007350	159	0.037
regulation of cellular localization	GO:0060341	136	0.036
nucleocytoplasmic transport	GO:0006913	72	0.036
locomotory behavior	GO:0007626	176	0.036
purine ribonucleoside catabolic process	GO:0046130	112	0.036
cellular pigmentation	GO:0033059	12	0.036
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.036
regulation of catabolic process	GO:0009894	170	0.036
regulation of proteasomal protein catabolic process	GO:0061136	39	0.035
muscle thin filament assembly	GO:0071689	5	0.035
positive regulation of translation	GO:0045727	12	0.035
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.035
renal system development	GO:0072001	72	0.035
regulation of membrane potential	GO:0042391	35	0.035
positive regulation of multicellular organism growth	GO:0040018	21	0.035
positive regulation of apoptotic process	GO:0043065	47	0.034
organonitrogen compound catabolic process	GO:1901565	128	0.034
glycosyl compound catabolic process	GO:1901658	112	0.034
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.034
negative regulation of cellular catabolic process	GO:0031330	34	0.034
regulation of intracellular transport	GO:0032386	64	0.034
regulation of catalytic activity	GO:0050790	185	0.034
positive regulation of cell proliferation	GO:0008284	47	0.034
positive regulation of phosphorus metabolic process	GO:0010562	139	0.033
gene silencing by rna	GO:0031047	57	0.033
gonad development	GO:0008406	50	0.033	Worm
autophagy	GO:0006914	108	0.033
telencephalon development	GO:0021537	2	0.033
protein phosphorylation	GO:0006468	169	0.032
regulation of stem cell differentiation	GO:2000736	14	0.032
cellular response to abiotic stimulus	GO:0071214	58	0.032
maintenance of location	GO:0051235	73	0.032	Worm
negative regulation of cellular component organization	GO:0051129	108	0.031
oviposition	GO:0018991	19	0.031
translational initiation	GO:0006413	11	0.031
carbohydrate derivative catabolic process	GO:1901136	118	0.031
striated muscle cell differentiation	GO:0051146	90	0.031
nuclear transport	GO:0051169	72	0.031
positive regulation of transport	GO:0051050	92	0.031
negative regulation of neurogenesis	GO:0050768	53	0.031
translation	GO:0006412	69	0.030
actin polymerization or depolymerization	GO:0008154	31	0.030
asymmetric stem cell division	GO:0098722	49	0.030
protein targeting	GO:0006605	64	0.030
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.030
nucleoside monophosphate metabolic process	GO:0009123	52	0.030
rhabdomere development	GO:0042052	38	0.030
positive regulation of cellular amine metabolic process	GO:0033240	0	0.029
regulation of neuron differentiation	GO:0045664	103	0.029
female germ line stem cell maintenance	GO:0036099	8	0.029
regulation of actin filament polymerization	GO:0030833	25	0.029
nephron morphogenesis	GO:0072028	3	0.029
protein localization to nucleus	GO:0034504	55	0.029
response to decreased oxygen levels	GO:0036293	58	0.029
response to heat	GO:0009408	63	0.029	Yeast
macromolecular complex disassembly	GO:0032984	37	0.028
regulation of protein serine threonine kinase activity	GO:0071900	25	0.028
spindle localization	GO:0051653	22	0.028
arf protein signal transduction	GO:0032011	2	0.028
purine nucleoside catabolic process	GO:0006152	112	0.028
cell proliferation involved in imaginal disc derived wing morphogenesis	GO:0090255	2	0.028
negative regulation of cellular metabolic process	GO:0031324	382	0.028
cell type specific apoptotic process	GO:0097285	38	0.028
cystoblast division	GO:0007282	10	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.028
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.028
cell cycle checkpoint	GO:0000075	95	0.027
cellular component disassembly	GO:0022411	46	0.027
actin filament based movement	GO:0030048	26	0.027
response to carbon dioxide	GO:0010037	4	0.027
regulation of oocyte development	GO:0060281	27	0.027
oocyte maturation	GO:0001556	3	0.027
cell cycle arrest	GO:0007050	4	0.027
sex determination	GO:0007530	18	0.027
ribonucleoprotein complex biogenesis	GO:0022613	31	0.027
sister chromatid segregation	GO:0000819	92	0.027
negative regulation of rna metabolic process	GO:0051253	251	0.026
negative regulation of neuroblast proliferation	GO:0007406	27	0.026
tissue migration	GO:0090130	155	0.026
neuroblast proliferation	GO:0007405	74	0.026
phosphorylation	GO:0016310	294	0.026
mitotic cytokinesis	GO:0000281	50	0.026
carbohydrate derivative metabolic process	GO:1901135	217	0.025
digestive tract development	GO:0048565	149	0.025
negative regulation of apoptotic process	GO:0043066	63	0.025
single organism cell adhesion	GO:0098602	47	0.025
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.025
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.024
receptor mediated endocytosis	GO:0006898	21	0.024	Worm
border follicle cell migration	GO:0007298	113	0.024
hematopoietic or lymphoid organ development	GO:0048534	57	0.024
embryonic axis specification	GO:0000578	107	0.024
female germ line cyst encapsulation	GO:0048139	8	0.024
regulation of golgi to plasma membrane protein transport	GO:0042996	6	0.024
regulation of synapse structure and activity	GO:0050803	128	0.024
regulation of mitotic cell cycle	GO:0007346	190	0.024
golgi to plasma membrane transport	GO:0006893	8	0.024
regulation of hydrolase activity	GO:0051336	97	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.024
learning or memory	GO:0007611	141	0.024
circadian behavior	GO:0048512	76	0.024
positive regulation of response to stimulus	GO:0048584	323	0.024
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.023
neural precursor cell proliferation	GO:0061351	75	0.023
organonitrogen compound biosynthetic process	GO:1901566	117	0.023
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.023
striated muscle myosin thick filament assembly	GO:0071688	3	0.023
regulation of microtubule based process	GO:0032886	49	0.023
post embryonic appendage morphogenesis	GO:0035120	385	0.023
regulation of locomotion	GO:0040012	42	0.023
meiotic chromosome segregation	GO:0045132	59	0.023
blood circulation	GO:0008015	26	0.023
cytokinesis	GO:0000910	90	0.022
regulation of phosphate metabolic process	GO:0019220	210	0.022
mitotic spindle elongation	GO:0000022	81	0.022
regulation of protein transport	GO:0051223	57	0.022
regulation of programmed cell death	GO:0043067	152	0.022
synaptic transmission	GO:0007268	288	0.022
epithelial cell migration	GO:0010631	148	0.021
proteolysis	GO:0006508	192	0.021
olfactory behavior	GO:0042048	97	0.021
negative regulation of organelle organization	GO:0010639	56	0.021
fertilization	GO:0009566	26	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
response to wounding	GO:0009611	94	0.021
regulation of growth	GO:0040008	233	0.021
morphogenesis of an epithelium	GO:0002009	276	0.021
tor signaling	GO:0031929	32	0.020
development of primary female sexual characteristics	GO:0046545	12	0.020
regulation of protein phosphorylation	GO:0001932	64	0.020
rhythmic process	GO:0048511	106	0.020
regulation of cytoplasmic transport	GO:1903649	47	0.020
dephosphorylation	GO:0016311	51	0.020
embryonic pattern specification	GO:0009880	174	0.020
positive regulation of growth	GO:0045927	75	0.020
response to organic cyclic compound	GO:0014070	89	0.020
cullin deneddylation	GO:0010388	3	0.020
anterior posterior axis specification embryo	GO:0008595	103	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
positive regulation of phosphorylation	GO:0042327	87	0.020
organ induction	GO:0001759	3	0.019
cell elongation involved in imaginal disc derived wing morphogenesis	GO:0090254	5	0.019
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.019
aggressive behavior	GO:0002118	63	0.019
mitotic dna damage checkpoint	GO:0044773	74	0.019
axis specification	GO:0009798	167	0.019
limb development	GO:0060173	1	0.019
positive regulation of cell differentiation	GO:0045597	64	0.019
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.019

eff disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	congenital nervous system abnormality	DOID:2490	0	0.025
	physical disorder	DOID:0080015	0	0.025

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