Drosophila melanogaster

0 known processes

PRL-1 (Dmel_CG4993)

CG4993 gene product from transcript CG4993-RB

(Aliases: BcDNA:RE40268,CG4993,PRL,PrL-1,BG:DS07473.3,Dmel\CG4993)

PRL-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
developmental growthGO:00485892800.566
regulation of growthGO:00400082330.432
growthGO:00400073590.344
establishment of localization in cellGO:00516494020.316
single organism intracellular transportGO:19025822070.291
hippo signalingGO:0035329200.288
intracellular transportGO:00469072280.284
positive regulation of nucleic acid templated transcriptionGO:19035082660.256
deathGO:00162652840.250
endocytosisGO:00068973100.249
regulation of protein metabolic processGO:00512462560.241
regulation of apoptotic processGO:00429811300.230
regulation of developmental growthGO:00486381740.218
cellular protein modification processGO:00064644380.213
apoptotic processGO:00069151590.208
cytoplasmic transportGO:00164821300.196
cellular response to dna damage stimulusGO:00069742230.187
negative regulation of cellular metabolic processGO:00313243820.174
programmed cell deathGO:00125012570.173
positive regulation of macromolecule metabolic processGO:00106044050.168
cell deathGO:00082192790.163
g protein coupled receptor signaling pathwayGO:00071861360.161
neurological system processGO:00508773580.154
negative regulation of multicellular organismal processGO:00512411420.152
positive regulation of phosphate metabolic processGO:00459371390.142
negative regulation of cell communicationGO:00106482230.142
regulation of mitotic cell cycleGO:00073461900.129
proteolysisGO:00065081920.127
negative regulation of biosynthetic processGO:00098902770.124
maintenance of locationGO:0051235730.124
regulation of programmed cell deathGO:00430671520.123
regulation of phosphorylationGO:00423251470.120
positive regulation of gene expressionGO:00106282900.117
regulation of cell cycleGO:00517262910.117
cellular response to abiotic stimulusGO:0071214580.116
protein localizationGO:00081042840.113
cellular response to light stimulusGO:0071482370.106
negative regulation of gene expressionGO:00106293870.106
response to organic substanceGO:00100332840.105
taxisGO:00423303040.104
negative regulation of signalingGO:00230572190.102
vesicle mediated transportGO:00161923810.100
regulation of molecular functionGO:00650092170.099
nucleocytoplasmic transportGO:0006913720.096
cell growthGO:00160491080.092
cell proliferationGO:00082832990.092
response to light stimulusGO:00094161240.092
activation of innate immune responseGO:000221840.089
negative regulation of response to stimulusGO:00485852580.089
regulation of cell deathGO:00109411730.085
adult behaviorGO:00305341370.084
tube developmentGO:00352952440.082
phosphorylationGO:00163102940.081
negative regulation of signal transductionGO:00099682060.080
positive regulation of secretionGO:0051047220.080
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.079
negative regulation of programmed cell deathGO:0043069720.079
positive regulation of cellular protein metabolic processGO:00322701180.078
jnk cascadeGO:0007254500.077
multicellular organismal homeostasisGO:0048871410.077
tor signalingGO:0031929320.076
regulation of cellular localizationGO:00603411360.072
protein targetingGO:0006605640.070
cell type specific apoptotic processGO:0097285380.069
positive regulation of phosphorylationGO:0042327870.068
multicellular organism growthGO:0035264460.066
mapk cascadeGO:00001651070.065
negative regulation of cell deathGO:0060548810.065
negative regulation of mitotic cell cycleGO:00459301090.065
dna repairGO:0006281540.064
regulation of transcription from rna polymerase ii promoterGO:00063573780.062
cell divisionGO:00513012480.062
negative regulation of macromolecule biosynthetic processGO:00105582700.061
regulation of cell proliferationGO:00421271630.060
tube morphogenesisGO:00352391910.060
negative regulation of cellular biosynthetic processGO:00313272770.060
axon guidanceGO:00074112330.059
regulation of phosphorus metabolic processGO:00511742100.058
single organism carbohydrate metabolic processGO:0044723720.057
protein modification processGO:00362114380.056
neuron projection guidanceGO:00974852410.056
regulation of cellular protein metabolic processGO:00322682430.055
cellular response to radiationGO:0071478520.055
regulation of i kappab kinase nf kappab signalingGO:004312220.055
regulation of multi organism processGO:00439001310.054
innate immune response activating signal transductionGO:000275820.053
mitotic cell cycle phase transitionGO:00447721380.053
response to ethanolGO:0045471590.052
response to abiotic stimulusGO:00096283410.052
axon developmentGO:00615642970.052
organelle localizationGO:00516401480.052
negative regulation of apoptotic processGO:0043066630.050
chemotaxisGO:00069352490.050
positive regulation of cellular biosynthetic processGO:00313283160.049
intracellular signal transductionGO:00355563000.049
regionalizationGO:00030024160.048
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.047
regulation of secretionGO:0051046440.047
cellular catabolic processGO:00442483720.047
positive regulation of transcription dna templatedGO:00458932660.046
transcription from rna polymerase ii promoterGO:00063663680.045
cell cycle phase transitionGO:00447701400.045
regulation of organelle organizationGO:00330431960.044
positive regulation of multicellular organismal processGO:00512401430.044
regulation of intracellular signal transductionGO:19025312360.044
organic substance transportGO:00717022570.044
embryonic morphogenesisGO:00485982060.044
negative regulation of growthGO:0045926840.043
positive regulation of phosphorus metabolic processGO:00105621390.043
cellular chemical homeostasisGO:0055082400.042
negative regulation of cell cycleGO:00457861160.042
regulation of transportGO:00510491810.042
cellular macromolecule localizationGO:00707272200.041
single organism catabolic processGO:00447122280.041
positive regulation of molecular functionGO:00440931360.040
cellular response to organic substanceGO:00713101320.040
regulation of cell sizeGO:0008361630.040
negative regulation of transcription dna templatedGO:00458922370.040
response to starvationGO:0042594970.040
response to radiationGO:00093141550.040
carbohydrate metabolic processGO:0005975820.039
heart processGO:0003015370.039
single organism cellular localizationGO:19025801800.039
regulation of anatomical structure sizeGO:00900661630.038
signal transduction by phosphorylationGO:00230141070.038
negative regulation of nitrogen compound metabolic processGO:00511722650.038
maintenance of protein locationGO:0045185280.038
organonitrogen compound metabolic processGO:19015643180.037
organic substance catabolic processGO:19015753080.037
positive regulation of mapk cascadeGO:0043410630.036
catabolic processGO:00090564090.036
regulation of catabolic processGO:00098941700.036
ras protein signal transductionGO:0007265880.036
positive regulation of protein metabolic processGO:00512471280.036
homeostatic processGO:00425921990.036
response to nitrogen compoundGO:1901698900.036
regulation of stress activated protein kinase signaling cascadeGO:0070302420.036
regulation of cell cycle processGO:00105641810.035
cellular protein localizationGO:00346131600.035
regulation of cellular component sizeGO:0032535980.035
regulation of locomotionGO:0040012420.035
regulation of mapk cascadeGO:0043408920.035
regulation of protein kinase activityGO:0045859510.035
cellular response to mechanical stimulusGO:007126020.034
mrna metabolic processGO:00160711240.034
cell migrationGO:00164772380.033
protein transportGO:00150311550.033
regulation of cellular catabolic processGO:00313291570.032
pigmentationGO:0043473750.032
response to oxygen containing compoundGO:19017002000.032
defense responseGO:00069523000.032
tissue morphogenesisGO:00487292970.031
immune response regulating signaling pathwayGO:000276420.031
cellular response to endogenous stimulusGO:0071495800.031
positive regulation of signal transductionGO:00099672230.031
positive regulation of developmental processGO:00510941430.031
cardiovascular system developmentGO:0072358820.031
regulation of response to stressGO:00801342000.031
regulation of secretion by cellGO:1903530390.030
notch signaling pathwayGO:00072191200.030
pattern recognition receptor signaling pathwayGO:000222120.030
phagocytosisGO:00069092150.030
small gtpase mediated signal transductionGO:0007264880.030
positive regulation of signalingGO:00230562430.029
cell adhesionGO:00071551360.029
protein localization to organelleGO:0033365820.029
regulation of cell developmentGO:00602842150.029
regulation of hippo signalingGO:0035330140.029
open tracheal system developmentGO:00074242040.029
regulation of phosphate metabolic processGO:00192202100.028
regulation of jnk cascadeGO:0046328400.028
intracellular protein transportGO:00068861040.028
biological adhesionGO:00226101380.028
post embryonic appendage morphogenesisGO:00351203850.028
positive regulation of apoptotic processGO:0043065470.027
organophosphate metabolic processGO:00196371950.027
erk1 and erk2 cascadeGO:0070371390.027
regulation of localizationGO:00328792750.027
positive regulation of rna biosynthetic processGO:19026802660.027
oxoacid metabolic processGO:00434361030.027
larval developmentGO:00021641040.026
positive regulation of intracellular signal transductionGO:19025331160.026
neuron deathGO:0070997270.026
nuclear transportGO:0051169720.026
neuronal action potentialGO:0019228100.026
detection of stimulus involved in sensory perceptionGO:0050906920.026
gliogenesisGO:0042063800.025
cellular ion homeostasisGO:0006873390.025
positive regulation of programmed cell deathGO:0043068620.025
response to glucoseGO:000974920.025
synaptic transmissionGO:00072682880.025
cation homeostasisGO:0055080510.025
response to extracellular stimulusGO:00099911160.025
establishment of protein localization to organelleGO:0072594620.024
mitotic spindle organizationGO:00070522200.024
cellular homeostasisGO:0019725800.024
body morphogenesisGO:001017120.024
mitotic nuclear divisionGO:00070672130.024
stress activated mapk cascadeGO:0051403520.024
extrinsic apoptotic signaling pathwayGO:009719110.023
regulation of proteolysisGO:0030162870.023
dna metabolic processGO:00062592270.023
dorsal ventral pattern formationGO:00099531330.023
response to nutrient levelsGO:00316671140.023
positive regulation of defense responseGO:0031349590.023
nucleobase containing compound catabolic processGO:00346551650.023
gland developmentGO:00487321910.023
negative regulation of heart rateGO:001045930.023
response to alcoholGO:0097305950.023
cell fate specificationGO:0001708710.023
regulation of multicellular organism growthGO:0040014400.022
negative regulation of intracellular signal transductionGO:1902532570.022
ensheathment of neuronsGO:0007272100.022
skeletal muscle fiber developmentGO:004874130.022
lipid localizationGO:0010876540.022
positive regulation of rna metabolic processGO:00512542710.022
regulation of nucleocytoplasmic transportGO:0046822350.022
cation transportGO:00068121100.022
morphogenesis of a branching structureGO:0001763450.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
regulation of cellular ketone metabolic processGO:001056530.021
ribosomal large subunit biogenesisGO:004227310.021
wing disc morphogenesisGO:00074723440.021
stress activated protein kinase signaling cascadeGO:0031098550.021
circulatory system developmentGO:0072359820.021
negative regulation of mitotic cell cycle phase transitionGO:19019911030.021
digestive tract developmentGO:00485651490.021
positive regulation of growthGO:0045927750.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
regulation of kinase activityGO:0043549530.021
axonogenesisGO:00074092900.020
embryo development ending in birth or egg hatchingGO:00097921520.020
positive regulation of cell sizeGO:0045793210.020
negative regulation of rna biosynthetic processGO:19026792400.020
appendage developmentGO:00487364010.020
negative regulation of cell cycle processGO:00109481090.020
regulation of catalytic activityGO:00507901850.020
organic acid metabolic processGO:00060821030.020
regulation of protein modification processGO:00313991120.020
positive regulation of cell communicationGO:00106472500.020
cellular ketone metabolic processGO:0042180240.020
regulation of stress activated mapk cascadeGO:0032872410.019
protein processingGO:0016485680.019
regulation of response to external stimulusGO:00321011150.019
appendage morphogenesisGO:00351073970.019
action potentialGO:0001508130.019
muscle structure developmentGO:00610612240.019
immune system processGO:00023763470.019
reproductive structure developmentGO:0048608740.019
connective tissue developmentGO:006144830.019
positive regulation of cell deathGO:0010942690.019
imaginal disc derived wing morphogenesisGO:00074763370.019
protein hydroxylationGO:001812610.018
striated muscle tissue developmentGO:0014706270.018
signal releaseGO:0023061490.018
protein targeting to nucleusGO:0044744510.018
regulation of neuron apoptotic processGO:0043523160.018
regulation of cell divisionGO:0051302720.018
negative regulation of notch signaling pathwayGO:0045746410.018
aromatic compound catabolic processGO:00194391660.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
cellular carbohydrate metabolic processGO:0044262220.018
regulation of mitosisGO:0007088560.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
positive regulation of cell migrationGO:003033520.018
renal system developmentGO:0072001720.018
organ growthGO:0035265560.017
regulation of sequestering of calcium ionGO:005128230.017
compound eye photoreceptor developmentGO:0042051780.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
single organismal cell cell adhesionGO:0016337450.017
establishment of protein localizationGO:00451841630.017
regulation of g protein coupled receptor protein signaling pathwayGO:0008277230.017
protein phosphorylationGO:00064681690.017
response to endogenous stimulusGO:00097191190.017
chemical homeostasisGO:0048878920.017
positive regulation of cell motilityGO:200014730.017
morphogenesis of an epitheliumGO:00020092760.017
positive regulation of catalytic activityGO:00430851180.017
autophagic vacuole assemblyGO:000004520.017
carboxylic acid metabolic processGO:0019752920.016
rna processingGO:00063961470.016
deactivation of rhodopsin mediated signalingGO:0016059170.016
multicellular organismal signalingGO:0035637120.016
circadian rhythmGO:00076231050.016
epithelial cell differentiationGO:00308553220.016
purine nucleotide metabolic processGO:00061631460.016
regulation of embryonic developmentGO:0045995680.016
regulation of tor signalingGO:0032006210.016
positive regulation of autophagyGO:0010508210.016
organelle fissionGO:00482853400.016
negative regulation of developmental growthGO:0048640640.016
negative regulation of cell proliferationGO:0008285690.016
synapse assemblyGO:00074161430.015
negative regulation of cell differentiationGO:00455961430.015
purine ribonucleotide metabolic processGO:00091501450.015
regulation of multicellular organismal developmentGO:20000264140.015
cellular macromolecule catabolic processGO:00442651360.015
imaginal disc derived appendage developmentGO:00487373990.015
regulation of innate immune responseGO:0045088710.015
cellular response to carbohydrate stimulusGO:007132240.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
positive regulation of response to stimulusGO:00485843230.015
establishment or maintenance of cell polarityGO:00071631670.015
negative regulation of catabolic processGO:0009895360.015
regulation of cytoplasmic transportGO:1903649470.015
cell junction organizationGO:0034330570.015
nucleoside catabolic processGO:00091641120.015
maintenance of location in cellGO:0051651280.015
protein maturationGO:0051604710.014
secretion by cellGO:00329401010.014
compound eye developmentGO:00487493070.014
protein localization to nucleusGO:0034504550.014
cell cell junction organizationGO:0045216550.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
nitrogen compound transportGO:0071705850.014
regulation of protein localizationGO:0032880760.014
regulation of neurogenesisGO:00507671580.014
regulation of protein phosphorylationGO:0001932640.014
positive regulation of lipid catabolic processGO:005099610.014
positive regulation of kinase activityGO:0033674250.014
cellular response to monosaccharide stimulusGO:007132620.014
reproductive behaviorGO:00190981220.014
learning or memoryGO:00076111410.014
chromosome segregationGO:00070591570.014
anatomical structure homeostasisGO:0060249970.014
regulation of anatomical structure morphogenesisGO:00226032420.014
regulation of system processGO:0044057360.014
axis specificationGO:00097981670.014
sensory organ morphogenesisGO:00905962600.014
cellular response to biotic stimulusGO:007121640.014
protein import into nucleusGO:0006606510.014
response to hexoseGO:000974630.014
single organism cell adhesionGO:0098602470.014
endomembrane system organizationGO:00102561190.013
heart contractionGO:0060047260.013
cellular response to lipidGO:0071396200.013
negative regulation of organ growthGO:0046621150.013
regulation of mitotic sister chromatid segregationGO:0033047280.013
positive regulation of protein phosphorylationGO:0001934340.013
establishment of protein localization to peroxisomeGO:007266320.013
centrosome organizationGO:00512971630.013
cellular response to chemical stimulusGO:00708871990.013
regulation of notch signaling pathwayGO:00085931000.013
cellular response to external stimulusGO:0071496660.013
negative regulation of protein metabolic processGO:0051248850.013
nuclear importGO:0051170510.013
peptidyl amino acid modificationGO:00181931050.013
chromatin modificationGO:00165681470.013
insulin like growth factor receptor signaling pathwayGO:004800950.012
digestive tract morphogenesisGO:00485461270.012
single organism carbohydrate catabolic processGO:004472470.012
single organism membrane organizationGO:0044802930.012
positive regulation of biosynthetic processGO:00098913160.012
response to lipopolysaccharideGO:003249640.012
cellular nitrogen compound catabolic processGO:00442701650.012
regulation of establishment of protein localizationGO:0070201610.012
positive regulation of behaviorGO:0048520190.012
nucleotide metabolic processGO:00091171610.012
metal ion homeostasisGO:0055065440.012
glycosyl compound metabolic processGO:19016571270.012
positive regulation of transferase activityGO:0051347260.012
imaginal disc growthGO:0007446370.012
negative regulation of cell cycle phase transitionGO:19019881030.012
peptidyl threonine phosphorylationGO:001810720.012
small molecule metabolic processGO:00442813050.012
necrotic cell deathGO:007026510.012
meiosis iGO:0007127590.012
positive regulation of secretion by cellGO:1903532200.012
ribonucleotide metabolic processGO:00092591450.012
organonitrogen compound catabolic processGO:19015651280.012
positive regulation of immune system processGO:0002684680.012
regulation of neuron deathGO:1901214260.012
purine containing compound metabolic processGO:00725211550.012
immune response activating signal transductionGO:000275720.012
regulation of ras protein signal transductionGO:0046578930.012
spindle organizationGO:00070512530.012
cellular protein catabolic processGO:0044257830.012
regulation of small gtpase mediated signal transductionGO:0051056930.011
lateral inhibitionGO:00463312060.011
urogenital system developmentGO:0001655720.011
nuclear exportGO:0051168240.011
regulation of cellular response to stressGO:0080135890.011
instar larval developmentGO:0002168550.011
regulation of cellular amine metabolic processGO:003323830.011
regulation of cell cycle phase transitionGO:19019871300.011
hindbrain developmentGO:003090220.011
sex differentiationGO:0007548810.011
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.011
blood circulationGO:0008015260.011
secretionGO:00469031090.011
positive regulation of cellular component organizationGO:00511301560.011
chromatin silencingGO:0006342760.011
positive regulation of erk1 and erk2 cascadeGO:0070374360.011
positive regulation of jun kinase activityGO:004350740.011
rna 3 end processingGO:0031123450.011
rho protein signal transductionGO:0007266140.011
immune responseGO:00069552460.011
purine nucleoside catabolic processGO:00061521120.011
ribose phosphate metabolic processGO:00196931450.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
positive regulation of transportGO:0051050920.011
imaginal disc derived wing vein specificationGO:0007474480.011
cytokinesisGO:0000910900.011
compound eye morphogenesisGO:00017452490.011
ubiquitin dependent protein catabolic processGO:0006511780.011
positive regulation of protein modification processGO:0031401580.010
maintenance of gastrointestinal epitheliumGO:003027730.010
regulation of carbohydrate metabolic processGO:0006109100.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
regulation of cellular component movementGO:0051270420.010
regulation of protein transportGO:0051223570.010
regulation of hormone levelsGO:0010817400.010
synapse organizationGO:00508081960.010
response to woundingGO:0009611940.010
protein kinase b signalingGO:004349110.010
regulation of intracellular transportGO:0032386640.010
chromatin remodelingGO:0006338720.010
positive regulation of macroautophagyGO:001623980.010

PRL-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.041
acquired metabolic diseaseDOID:006015800.027
glucose metabolism diseaseDOID:419400.027
carbohydrate metabolism diseaseDOID:005001300.027
disease of metabolismDOID:001466700.027
organ system cancerDOID:005068600.021
cancerDOID:16200.021
diabetes mellitusDOID:935100.011