IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG9576 (Dmel_CG9576)

CG9576 gene product from transcript CG9576-RA

(Aliases: Dmel\CG9576)

FLYBASE: FBgn0031091
Entrez: 33015
UniProtKB: Q9W5W9

Process Predictions
Disease Predictions

CG9576 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
dna repair	GO:0006281	54	0.715
dna replication	GO:0006260	48	0.437
germ line stem cell maintenance	GO:0030718	50	0.371
dna metabolic process	GO:0006259	227	0.359
double strand break repair	GO:0006302	26	0.327
negative regulation of cell cycle	GO:0045786	116	0.247
dna recombination	GO:0006310	32	0.235
cellular macromolecule catabolic process	GO:0044265	136	0.215
cellular response to dna damage stimulus	GO:0006974	223	0.213
regulation of cell cycle phase transition	GO:1901987	130	0.201
catabolic process	GO:0009056	409	0.177
mitotic cell cycle checkpoint	GO:0007093	88	0.176
dna conformation change	GO:0071103	105	0.174
positive regulation of macromolecule metabolic process	GO:0010604	405	0.167
negative regulation of cell cycle phase transition	GO:1901988	103	0.161
embryonic morphogenesis	GO:0048598	206	0.157
cell cycle checkpoint	GO:0000075	95	0.153
establishment of localization in cell	GO:0051649	402	0.147
chromosome segregation	GO:0007059	157	0.145
proteolysis	GO:0006508	192	0.126
cellular catabolic process	GO:0044248	372	0.125
mitotic cell cycle phase transition	GO:0044772	138	0.125
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.122
dna dependent dna replication	GO:0006261	17	0.116
stem cell differentiation	GO:0048863	117	0.113
death	GO:0016265	284	0.110
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.107
glycosyl compound metabolic process	GO:1901657	127	0.106
response to bacterium	GO:0009617	198	0.106
negative regulation of cell cycle process	GO:0010948	109	0.096
dna geometric change	GO:0032392	16	0.095
secretion by cell	GO:0032940	101	0.090
mitotic nuclear division	GO:0007067	213	0.088
regulation of cell cycle process	GO:0010564	181	0.087
regulation of cellular localization	GO:0060341	136	0.084
single organism biosynthetic process	GO:0044711	206	0.084
negative regulation of mitotic cell cycle	GO:0045930	109	0.079
nucleobase containing compound catabolic process	GO:0034655	165	0.076
regulation of programmed cell death	GO:0043067	152	0.075
regulation of cellular protein metabolic process	GO:0032268	243	0.074
cell death	GO:0008219	279	0.074
intracellular transport	GO:0046907	228	0.073
purine containing compound metabolic process	GO:0072521	155	0.071
homeostatic process	GO:0042592	199	0.069
mitotic g2 m transition checkpoint	GO:0044818	70	0.069
actin filament based process	GO:0030029	220	0.069
purine ribonucleoside metabolic process	GO:0046128	127	0.068
sister chromatid segregation	GO:0000819	92	0.067
ribonucleotide metabolic process	GO:0009259	145	0.066
regulation of molecular function	GO:0065009	217	0.066
small molecule metabolic process	GO:0044281	305	0.065
nuclear dna replication	GO:0033260	1	0.064
ribonucleoside metabolic process	GO:0009119	127	0.062
aromatic compound catabolic process	GO:0019439	166	0.062
carbohydrate derivative metabolic process	GO:1901135	217	0.062
organelle fission	GO:0048285	340	0.061
recombinational repair	GO:0000725	13	0.060
secretion	GO:0046903	109	0.060
nucleoside phosphate metabolic process	GO:0006753	162	0.059
purine nucleoside metabolic process	GO:0042278	127	0.058
cellular protein catabolic process	GO:0044257	83	0.058
response to organic substance	GO:0010033	284	0.058
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.057
organic substance catabolic process	GO:1901575	308	0.057
double strand break repair via homologous recombination	GO:0000724	13	0.056
macromolecule catabolic process	GO:0009057	161	0.056
dna integrity checkpoint	GO:0031570	81	0.056
male gamete generation	GO:0048232	201	0.055
dna damage checkpoint	GO:0000077	78	0.055
embryo development ending in birth or egg hatching	GO:0009792	152	0.055
ubiquitin dependent protein catabolic process	GO:0006511	78	0.054
purine nucleotide metabolic process	GO:0006163	146	0.053
response to other organism	GO:0051707	293	0.053
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.053
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.052
negative regulation of cellular metabolic process	GO:0031324	382	0.052
regulation of cell death	GO:0010941	173	0.051
imaginal disc derived appendage development	GO:0048737	399	0.051
organonitrogen compound metabolic process	GO:1901564	318	0.051
regulation of cell cycle	GO:0051726	291	0.051
cellular nitrogen compound catabolic process	GO:0044270	165	0.051
programmed cell death	GO:0012501	257	0.050
nucleoside catabolic process	GO:0009164	112	0.049
single organism catabolic process	GO:0044712	228	0.049
regulation of localization	GO:0032879	275	0.049
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.049
cell cycle phase transition	GO:0044770	140	0.048
protein transport	GO:0015031	155	0.048
meiosis i	GO:0007127	59	0.047
organic cyclic compound catabolic process	GO:1901361	168	0.046
nucleoside metabolic process	GO:0009116	127	0.046
response to endogenous stimulus	GO:0009719	119	0.046
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.045
anatomical structure homeostasis	GO:0060249	97	0.045
positive regulation of transcription dna templated	GO:0045893	266	0.044
mitotic g2 dna damage checkpoint	GO:0007095	69	0.044
regulation of transport	GO:0051049	181	0.044
modification dependent protein catabolic process	GO:0019941	78	0.044
regulation of mitotic cell cycle	GO:0007346	190	0.043
chromosome organization	GO:0051276	360	0.043
positive regulation of transport	GO:0051050	92	0.042
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.042
apoptotic process	GO:0006915	159	0.042
heart morphogenesis	GO:0003007	32	0.042
mitotic dna integrity checkpoint	GO:0044774	75	0.042
nuclear division	GO:0000280	332	0.041
multi multicellular organism process	GO:0044706	123	0.041
protein localization	GO:0008104	284	0.040
negative regulation of cell differentiation	GO:0045596	143	0.040
stem cell maintenance	GO:0019827	67	0.039
positive regulation of cellular biosynthetic process	GO:0031328	316	0.039
regulation of dna recombination	GO:0000018	4	0.039
proteasomal protein catabolic process	GO:0010498	59	0.039
regulation of apoptotic process	GO:0042981	130	0.039
atp metabolic process	GO:0046034	49	0.039
maintenance of location	GO:0051235	73	0.039
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.038
nucleobase containing small molecule metabolic process	GO:0055086	174	0.038
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.037
positive regulation of biosynthetic process	GO:0009891	316	0.037
protein maturation	GO:0051604	71	0.037
protein catabolic process	GO:0030163	101	0.037
modification dependent macromolecule catabolic process	GO:0043632	79	0.037
purine ribonucleotide metabolic process	GO:0009150	145	0.037
negative regulation of protein metabolic process	GO:0051248	85	0.035
spindle organization	GO:0007051	253	0.035
meiotic cell cycle process	GO:1903046	132	0.035
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.035
single organism intracellular transport	GO:1902582	207	0.035
oocyte maturation	GO:0001556	3	0.035
regulation of hydrolase activity	GO:0051336	97	0.034
immune response	GO:0006955	246	0.033
positive regulation of protein metabolic process	GO:0051247	128	0.033
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.033
cognition	GO:0050890	141	0.033
cellular protein localization	GO:0034613	160	0.033
response to light stimulus	GO:0009416	124	0.032
stem cell division	GO:0017145	69	0.032
regulation of cell differentiation	GO:0045595	302	0.032
regulation of protein metabolic process	GO:0051246	256	0.032
negative regulation of apoptotic process	GO:0043066	63	0.032
positive regulation of molecular function	GO:0044093	136	0.031
response to radiation	GO:0009314	155	0.031
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.031
chromosome separation	GO:0051304	42	0.031
organophosphate metabolic process	GO:0019637	195	0.031
response to biotic stimulus	GO:0009607	294	0.031
heart process	GO:0003015	37	0.031
negative regulation of response to stimulus	GO:0048585	258	0.031
stem cell development	GO:0048864	79	0.031
nucleotide catabolic process	GO:0009166	109	0.031
negative regulation of programmed cell death	GO:0043069	72	0.029
spermatogenesis	GO:0007283	200	0.028
appendage morphogenesis	GO:0035107	397	0.028
ribonucleoside catabolic process	GO:0042454	112	0.028
positive regulation of rna metabolic process	GO:0051254	271	0.028
heterocycle catabolic process	GO:0046700	166	0.028
positive regulation of catalytic activity	GO:0043085	118	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.027
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.027
negative regulation of cell communication	GO:0010648	223	0.027
cytoplasmic transport	GO:0016482	130	0.027
regulation of secretion	GO:0051046	44	0.027
negative regulation of gene expression	GO:0010629	387	0.027
meiotic chromosome segregation	GO:0045132	59	0.027
nucleotide metabolic process	GO:0009117	161	0.027
appendage development	GO:0048736	401	0.027
ribose phosphate metabolic process	GO:0019693	145	0.027
negative regulation of transcription dna templated	GO:0045892	237	0.027
intracellular signal transduction	GO:0035556	300	0.027
sensory organ morphogenesis	GO:0090596	260	0.026
digestive tract development	GO:0048565	149	0.026
response to monosaccharide	GO:0034284	4	0.026
negative regulation of cell death	GO:0060548	81	0.025
glycosyl compound catabolic process	GO:1901658	112	0.025
mitotic sister chromatid segregation	GO:0000070	87	0.025
positive regulation of rna biosynthetic process	GO:1902680	266	0.025
purine ribonucleoside catabolic process	GO:0046130	112	0.025
innate immune response	GO:0045087	144	0.025
positive regulation of gene expression	GO:0010628	290	0.025
double strand break repair via nonhomologous end joining	GO:0006303	5	0.025
positive regulation of signal transduction	GO:0009967	223	0.025
regulation of dna metabolic process	GO:0051052	34	0.025
regulation of chromosome organization	GO:0033044	64	0.025
cell proliferation	GO:0008283	299	0.024
nucleoside monophosphate metabolic process	GO:0009123	52	0.024
negative regulation of rna metabolic process	GO:0051253	251	0.024
ribonucleotide catabolic process	GO:0009261	109	0.024
regulation of proteolysis	GO:0030162	87	0.024
regulation of cell division	GO:0051302	72	0.024
positive regulation of hydrolase activity	GO:0051345	78	0.024
negative regulation of cellular catabolic process	GO:0031330	34	0.023
mitotic dna damage checkpoint	GO:0044773	74	0.023
response to abiotic stimulus	GO:0009628	341	0.023
meiotic nuclear division	GO:0007126	151	0.023
regulation of cellular component biogenesis	GO:0044087	201	0.023
establishment of protein localization	GO:0045184	163	0.023
establishment of organelle localization	GO:0051656	122	0.023
positive regulation of programmed cell death	GO:0043068	62	0.023
regulation of cellular response to stress	GO:0080135	89	0.022
positive regulation of cell death	GO:0010942	69	0.022
regulation of protein catabolic process	GO:0042176	55	0.022
nucleoside triphosphate catabolic process	GO:0009143	108	0.022
regulation of catabolic process	GO:0009894	170	0.022
negative regulation of cellular protein metabolic process	GO:0032269	85	0.022
cell division	GO:0051301	248	0.022
defense response to other organism	GO:0098542	225	0.021
purine ribonucleotide catabolic process	GO:0009154	109	0.021
nucleoside triphosphate metabolic process	GO:0009141	120	0.021
macromolecular complex assembly	GO:0065003	256	0.021
camera type eye development	GO:0043010	4	0.021
positive regulation of cellular component organization	GO:0051130	156	0.021
purine containing compound catabolic process	GO:0072523	112	0.021
response to heat	GO:0009408	63	0.021
protein modification process	GO:0036211	438	0.021
epithelial tube morphogenesis	GO:0060562	88	0.020
response to nitrogen compound	GO:1901698	90	0.020
regulation of catalytic activity	GO:0050790	185	0.020
mitotic sister chromatid separation	GO:0051306	30	0.020
cellular macromolecule localization	GO:0070727	220	0.020
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.020
regulation of response to stress	GO:0080134	200	0.020
positive regulation of cellular protein metabolic process	GO:0032270	118	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
organophosphate catabolic process	GO:0046434	112	0.020
intracellular protein transport	GO:0006886	104	0.019
protein complex assembly	GO:0006461	200	0.019
regulation of nuclear division	GO:0051783	58	0.019
compound eye morphogenesis	GO:0001745	249	0.019
regulation of synapse organization	GO:0050807	110	0.019
regulation of cytoplasmic transport	GO:1903649	47	0.019
purine nucleoside catabolic process	GO:0006152	112	0.019
digestive tract morphogenesis	GO:0048546	127	0.019
reciprocal dna recombination	GO:0035825	19	0.018
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.018
nucleoside phosphate catabolic process	GO:1901292	110	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.018
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.018
tube development	GO:0035295	244	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.018
g2 dna damage checkpoint	GO:0031572	69	0.018
imaginal disc derived wing morphogenesis	GO:0007476	337	0.018
cellularization	GO:0007349	90	0.018
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.017
regulation of multicellular organismal development	GO:2000026	414	0.017
negative regulation of gene expression epigenetic	GO:0045814	77	0.017
cellular response to organic substance	GO:0071310	132	0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.017
tube morphogenesis	GO:0035239	191	0.017
wing disc morphogenesis	GO:0007472	344	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.017
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.017
regulation of proteasomal protein catabolic process	GO:0061136	39	0.016
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.016
post embryonic appendage morphogenesis	GO:0035120	385	0.016
organic acid metabolic process	GO:0006082	103	0.016
regulation of cellular catabolic process	GO:0031329	157	0.016
regulation of cell development	GO:0060284	215	0.016
negative regulation of signaling	GO:0023057	219	0.016
mitotic spindle organization	GO:0007052	220	0.016
tissue morphogenesis	GO:0048729	297	0.016
morphogenesis of an epithelium	GO:0002009	276	0.016
negative regulation of developmental process	GO:0051093	201	0.015
regulation of double strand break repair	GO:2000779	3	0.015
positive regulation of nucleoside metabolic process	GO:0045979	47	0.015
protein processing	GO:0016485	68	0.015
response to alcohol	GO:0097305	95	0.015
regulation of embryonic development	GO:0045995	68	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.015
meiotic cell cycle	GO:0051321	171	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.014
cellular ketone metabolic process	GO:0042180	24	0.014
g protein coupled receptor signaling pathway	GO:0007186	136	0.014
translesion synthesis	GO:0019985	2	0.014
dna biosynthetic process	GO:0071897	24	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
dna duplex unwinding	GO:0032508	16	0.014
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.014
negative regulation of signal transduction	GO:0009968	206	0.014
endomembrane system organization	GO:0010256	119	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.013
positive regulation of cell communication	GO:0010647	250	0.013
single organism cellular localization	GO:1902580	180	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
organ growth	GO:0035265	56	0.013
regulation of protein complex disassembly	GO:0043244	29	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
maintenance of protein location in cell	GO:0032507	26	0.013
organelle localization	GO:0051640	148	0.013
negative regulation of protein depolymerization	GO:1901880	23	0.013
neurological system process	GO:0050877	358	0.012
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.012
adult behavior	GO:0030534	137	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
regulation of response to dna damage stimulus	GO:2001020	23	0.012
negative regulation of biosynthetic process	GO:0009890	277	0.012
developmental growth	GO:0048589	280	0.012
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.012
negative regulation of intracellular signal transduction	GO:1902532	57	0.012
regulation of nucleoside metabolic process	GO:0009118	50	0.011
dna packaging	GO:0006323	91	0.011
chromatin silencing	GO:0006342	76	0.011
protein complex biogenesis	GO:0070271	201	0.011
oxoacid metabolic process	GO:0043436	103	0.011
gtp catabolic process	GO:0006184	72	0.011
positive regulation of developmental growth	GO:0048639	62	0.011
positive regulation of signaling	GO:0023056	243	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.011
immune system process	GO:0002376	347	0.011
mitotic cytokinesis	GO:0000281	50	0.011
regulation of synapse assembly	GO:0051963	94	0.011
brain development	GO:0007420	120	0.011
postreplication repair	GO:0006301	2	0.011
organic substance transport	GO:0071702	257	0.011
positive regulation of nucleotide catabolic process	GO:0030813	46	0.011
mrna metabolic process	GO:0016071	124	0.011
mrna splicing via spliceosome	GO:0000398	73	0.011
regulation of protein localization	GO:0032880	76	0.011
translation	GO:0006412	69	0.011
response to oxygen containing compound	GO:1901700	200	0.011
regulation of endopeptidase activity	GO:0052548	36	0.011
positive regulation of protein transport	GO:0051222	37	0.011
golgi organization	GO:0007030	66	0.011
cellular response to lipopolysaccharide	GO:0071222	3	0.011
connective tissue development	GO:0061448	3	0.010
regulation of immune system process	GO:0002682	176	0.010
cell motility	GO:0048870	251	0.010
dna endoreduplication	GO:0042023	22	0.010
gene silencing	GO:0016458	138	0.010
eye development	GO:0001654	323	0.010	Fly
purine nucleotide catabolic process	GO:0006195	109	0.010
actin cytoskeleton organization	GO:0030036	206	0.010
cellular homeostasis	GO:0019725	80	0.010
defense response	GO:0006952	300	0.010
phosphorylation	GO:0016310	294	0.010

CG9576 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.021
disease of cellular proliferation	DOID:14566	0.013
nervous system disease	DOID:863	0.011
disease of metabolism	DOID:0014667	0.011

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