IMP: Integrative Multi-species Prediction

Drosophila melanogaster

20 known processes

Rab35 (Dmel_CG9575)

CG9575 gene product from transcript CG9575-RA

(Aliases: CG9575,Dmel\CG9575,DRab35,dRab35,DmRab35)

FLYBASE: FBgn0031090
Entrez: 33014
UniProtKB: F0JAF7
UniProtKB: Q9W5X0

Process Predictions
Disease Predictions

Rab35 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
transcription from rna polymerase ii promoter	GO:0006366	368	0.270
establishment of localization in cell	GO:0051649	402	0.267	Human
negative regulation of response to stimulus	GO:0048585	258	0.198
imaginal disc derived wing morphogenesis	GO:0007476	337	0.188
regulation of multicellular organismal development	GO:2000026	414	0.166
negative regulation of cellular biosynthetic process	GO:0031327	277	0.162
imaginal disc derived appendage development	GO:0048737	399	0.156
positive regulation of rna metabolic process	GO:0051254	271	0.149
negative regulation of transcription dna templated	GO:0045892	237	0.148
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.141
wing disc morphogenesis	GO:0007472	344	0.141
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.140
organophosphate metabolic process	GO:0019637	195	0.113	Human Yeast
cellular macromolecule localization	GO:0070727	220	0.109	Human Rat
protein localization	GO:0008104	284	0.107	Human Rat
organelle assembly	GO:0070925	198	0.104
neuromuscular junction development	GO:0007528	149	0.102
appendage morphogenesis	GO:0035107	397	0.097
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.091
cellular protein modification process	GO:0006464	438	0.086
negative regulation of gene expression	GO:0010629	387	0.084
organic substance catabolic process	GO:1901575	308	0.083	Human Yeast
regulation of anatomical structure morphogenesis	GO:0022603	242	0.082
purine nucleotide metabolic process	GO:0006163	146	0.081	Human Yeast
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.081
secretion by cell	GO:0032940	101	0.077
vesicle mediated transport	GO:0016192	381	0.076
regulation of nervous system development	GO:0051960	248	0.075
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.074
signal release	GO:0023061	49	0.072
organonitrogen compound metabolic process	GO:1901564	318	0.069	Human Yeast
cellular catabolic process	GO:0044248	372	0.067	Human Yeast
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.066
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.066
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.062
post embryonic appendage morphogenesis	GO:0035120	385	0.059
positive regulation of response to stimulus	GO:0048584	323	0.059
secretion	GO:0046903	109	0.059
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.059
dendrite development	GO:0016358	204	0.059
positive regulation of gene expression	GO:0010628	290	0.059
negative regulation of signaling	GO:0023057	219	0.058
regulation of autophagy	GO:0010506	62	0.057
negative regulation of signal transduction	GO:0009968	206	0.057
regulation of cell development	GO:0060284	215	0.056
regulation of localization	GO:0032879	275	0.056
muscle structure development	GO:0061061	224	0.054
positive regulation of multicellular organismal process	GO:0051240	143	0.052
axonogenesis	GO:0007409	290	0.052
purine containing compound metabolic process	GO:0072521	155	0.052	Human Yeast
eye morphogenesis	GO:0048592	260	0.051
sensory organ morphogenesis	GO:0090596	260	0.051
establishment of protein localization	GO:0045184	163	0.050
positive regulation of developmental process	GO:0051094	143	0.050
catabolic process	GO:0009056	409	0.050	Human Yeast
negative regulation of cell communication	GO:0010648	223	0.049
regulation of cellular localization	GO:0060341	136	0.049
positive regulation of macromolecule metabolic process	GO:0010604	405	0.049
positive regulation of cell communication	GO:0010647	250	0.049
membrane organization	GO:0061024	112	0.048
intracellular signal transduction	GO:0035556	300	0.047
organic substance transport	GO:0071702	257	0.047
positive regulation of cellular component organization	GO:0051130	156	0.047
cellular component assembly involved in morphogenesis	GO:0010927	151	0.046
small molecule metabolic process	GO:0044281	305	0.046	Human Yeast
protein transport	GO:0015031	155	0.046
appendage development	GO:0048736	401	0.046
forebrain development	GO:0030900	2	0.045
negative regulation of cellular metabolic process	GO:0031324	382	0.045
positive regulation of transcription dna templated	GO:0045893	266	0.044
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.044
purine ribonucleotide metabolic process	GO:0009150	145	0.044	Human Yeast
protein modification process	GO:0036211	438	0.044
regulation of transport	GO:0051049	181	0.044
dendrite morphogenesis	GO:0048813	199	0.044
tube morphogenesis	GO:0035239	191	0.043
cellular protein localization	GO:0034613	160	0.042	Human Rat
localization of cell	GO:0051674	257	0.042
growth	GO:0040007	359	0.041
cellular response to organic substance	GO:0071310	132	0.041	Rat
negative regulation of rna metabolic process	GO:0051253	251	0.041
regulation of cell differentiation	GO:0045595	302	0.041
negative regulation of biosynthetic process	GO:0009890	277	0.041
negative regulation of nervous system development	GO:0051961	92	0.041
negative regulation of rna biosynthetic process	GO:1902679	240	0.040
synapse assembly	GO:0007416	143	0.040
ribose phosphate metabolic process	GO:0019693	145	0.039	Human Yeast
negative regulation of cellular component organization	GO:0051129	108	0.039
positive regulation of rna biosynthetic process	GO:1902680	266	0.039
negative regulation of developmental process	GO:0051093	201	0.039
positive regulation of cellular biosynthetic process	GO:0031328	316	0.039
single organism cellular localization	GO:1902580	180	0.039
programmed cell death	GO:0012501	257	0.037
muscle cell differentiation	GO:0042692	103	0.037
intracellular protein transport	GO:0006886	104	0.037
developmental growth	GO:0048589	280	0.036
nucleotide metabolic process	GO:0009117	161	0.036	Human Yeast
vesicle organization	GO:0016050	44	0.036
regulation of phosphorus metabolic process	GO:0051174	210	0.035
compound eye development	GO:0048749	307	0.035
positive regulation of phosphate metabolic process	GO:0045937	139	0.034
telencephalon development	GO:0021537	2	0.034
regulation of response to stress	GO:0080134	200	0.034
phagocytosis	GO:0006909	215	0.033
response to organic substance	GO:0010033	284	0.033	Rat
male gamete generation	GO:0048232	201	0.033
cell projection assembly	GO:0030031	94	0.032
positive regulation of catabolic process	GO:0009896	105	0.032
regulation of gene expression epigenetic	GO:0040029	128	0.032
regulation of neurogenesis	GO:0050767	158	0.031
cellular protein catabolic process	GO:0044257	83	0.031
macromolecule catabolic process	GO:0009057	161	0.031
positive regulation of signaling	GO:0023056	243	0.031
dna metabolic process	GO:0006259	227	0.030
death	GO:0016265	284	0.030
organelle localization	GO:0051640	148	0.030
posttranscriptional regulation of gene expression	GO:0010608	145	0.030
axon development	GO:0061564	297	0.029
macromolecular complex assembly	GO:0065003	256	0.029
regulation of catalytic activity	GO:0050790	185	0.029
mitotic nuclear division	GO:0007067	213	0.029
macroautophagy	GO:0016236	42	0.029
endocytosis	GO:0006897	310	0.029
positive regulation of cell development	GO:0010720	61	0.029
cytoplasmic transport	GO:0016482	130	0.029	Human
positive regulation of catalytic activity	GO:0043085	118	0.029
defense response to bacterium	GO:0042742	178	0.028
neuron recognition	GO:0008038	101	0.028
regulation of nucleotide metabolic process	GO:0006140	62	0.028
regulation of cellular component biogenesis	GO:0044087	201	0.028
organic cyclic compound catabolic process	GO:1901361	168	0.027	Human Yeast
defense response to other organism	GO:0098542	225	0.027
epithelial cell differentiation	GO:0030855	322	0.027
regulation of cellular catabolic process	GO:0031329	157	0.027
single organism intracellular transport	GO:1902582	207	0.027	Human
positive regulation of signal transduction	GO:0009967	223	0.027
synapse organization	GO:0050808	196	0.027
cell death	GO:0008219	279	0.027
spindle organization	GO:0007051	253	0.027
taxis	GO:0042330	304	0.026
exocytosis	GO:0006887	28	0.026
synaptic transmission	GO:0007268	288	0.026
epithelial cell development	GO:0002064	274	0.026
regulation of response to external stimulus	GO:0032101	115	0.026
establishment of vesicle localization	GO:0051650	51	0.026
nucleobase containing small molecule metabolic process	GO:0055086	174	0.025	Human Yeast
nucleoside phosphate metabolic process	GO:0006753	162	0.025	Human Yeast
synaptic growth at neuromuscular junction	GO:0051124	119	0.025
ribonucleotide catabolic process	GO:0009261	109	0.025	Human Yeast
tissue morphogenesis	GO:0048729	297	0.025
single organism membrane organization	GO:0044802	93	0.025
regulation of secretion by cell	GO:1903530	39	0.025
central nervous system development	GO:0007417	201	0.024
regulation of neuron differentiation	GO:0045664	103	0.024
morphogenesis of an epithelium	GO:0002009	276	0.024
negative regulation of multicellular organismal process	GO:0051241	142	0.024
regulation of secretion	GO:0051046	44	0.024
response to other organism	GO:0051707	293	0.024
regulation of cell death	GO:0010941	173	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.023
striated muscle cell development	GO:0055002	50	0.023
regulation of molecular function	GO:0065009	217	0.023
positive regulation of biosynthetic process	GO:0009891	316	0.023
phosphorylation	GO:0016310	294	0.023
glycosyl compound metabolic process	GO:1901657	127	0.023	Human Yeast
regulation of immune response	GO:0050776	118	0.023
embryonic development via the syncytial blastoderm	GO:0001700	148	0.023
positive regulation of secretion	GO:0051047	22	0.023
positive regulation of phosphorus metabolic process	GO:0010562	139	0.023
regulation of intracellular signal transduction	GO:1902531	236	0.023
cellularization	GO:0007349	90	0.023
compound eye morphogenesis	GO:0001745	249	0.022
mapk cascade	GO:0000165	107	0.022
regulation of organelle organization	GO:0033043	196	0.022
regulation of phosphate metabolic process	GO:0019220	210	0.022
neurotransmitter transport	GO:0006836	37	0.022
response to external biotic stimulus	GO:0043207	293	0.022
intracellular transport	GO:0046907	228	0.022	Human
organelle fission	GO:0048285	340	0.022
regulation of catabolic process	GO:0009894	170	0.022
ribonucleotide metabolic process	GO:0009259	145	0.022	Human Yeast
regulation of cellular amino acid metabolic process	GO:0006521	0	0.021
regulation of erbb signaling pathway	GO:1901184	42	0.021
single organism carbohydrate metabolic process	GO:0044723	72	0.021
ovarian follicle cell development	GO:0030707	248	0.021
embryo development ending in birth or egg hatching	GO:0009792	152	0.021
response to biotic stimulus	GO:0009607	294	0.021
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.021	Human Yeast
carbohydrate derivative catabolic process	GO:1901136	118	0.021	Human Yeast
striated muscle cell differentiation	GO:0051146	90	0.021
positive regulation of cellular catabolic process	GO:0031331	95	0.021
aromatic compound catabolic process	GO:0019439	166	0.020	Human Yeast
protein modification by small protein conjugation or removal	GO:0070647	106	0.020
cation transport	GO:0006812	110	0.020
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.020	Human Yeast
regulation of cell cycle	GO:0051726	291	0.020
protein localization to organelle	GO:0033365	82	0.019	Human Rat
regulation of growth	GO:0040008	233	0.019
purine ribonucleoside metabolic process	GO:0046128	127	0.019	Human Yeast
negative regulation of neurogenesis	GO:0050768	53	0.019
cellular response to starvation	GO:0009267	61	0.019
positive regulation of cell death	GO:0010942	69	0.019
chemotaxis	GO:0006935	249	0.019
cellular nitrogen compound catabolic process	GO:0044270	165	0.019	Human Yeast
neuromuscular synaptic transmission	GO:0007274	67	0.019
blastoderm segmentation	GO:0007350	159	0.019
anterior posterior axis specification embryo	GO:0008595	103	0.019
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.019
proteolysis	GO:0006508	192	0.019
organophosphate catabolic process	GO:0046434	112	0.019	Human Yeast
cellular response to abiotic stimulus	GO:0071214	58	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.018
body morphogenesis	GO:0010171	2	0.018
asymmetric protein localization	GO:0008105	33	0.018
cellular response to chemical stimulus	GO:0070887	199	0.018	Rat
negative regulation of cell differentiation	GO:0045596	143	0.018
anterior posterior axis specification	GO:0009948	109	0.018
cell division	GO:0051301	248	0.018
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.018
glycosyl compound catabolic process	GO:1901658	112	0.018	Human Yeast
regulation of protein transport	GO:0051223	57	0.018
regulation of multi organism process	GO:0043900	131	0.018
golgi organization	GO:0007030	66	0.018
purine nucleotide catabolic process	GO:0006195	109	0.017	Human Yeast
cellular ketone metabolic process	GO:0042180	24	0.017
anatomical structure homeostasis	GO:0060249	97	0.017
regulation of cell projection organization	GO:0031344	92	0.017
developmental maturation	GO:0021700	172	0.017
regulation of defense response	GO:0031347	102	0.017
cell recognition	GO:0008037	102	0.017
regulation of protein localization	GO:0032880	76	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
epithelial tube morphogenesis	GO:0060562	88	0.017
locomotory behavior	GO:0007626	176	0.017
larval development	GO:0002164	104	0.017
spinal cord development	GO:0021510	1	0.016
purine ribonucleoside catabolic process	GO:0046130	112	0.016	Human Yeast
nucleoside triphosphate metabolic process	GO:0009141	120	0.016	Human Yeast
gtp catabolic process	GO:0006184	72	0.016	Human Yeast
modification dependent macromolecule catabolic process	GO:0043632	79	0.016
axon guidance	GO:0007411	233	0.016
ribonucleoside catabolic process	GO:0042454	112	0.016	Human Yeast
meiotic chromosome segregation	GO:0045132	59	0.016
muscle cell development	GO:0055001	50	0.016
autophagy	GO:0006914	108	0.016
protein targeting	GO:0006605	64	0.016
cellular component disassembly	GO:0022411	46	0.016
organic acid metabolic process	GO:0006082	103	0.016
regulation of cellular response to stress	GO:0080135	89	0.016
wnt signaling pathway	GO:0016055	98	0.016
spermatogenesis	GO:0007283	200	0.016
regulation of dendrite morphogenesis	GO:0048814	28	0.016
reproductive system development	GO:0061458	74	0.015
ubiquitin dependent protein catabolic process	GO:0006511	78	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
heterocycle catabolic process	GO:0046700	166	0.015	Human Yeast
positive regulation of cell migration	GO:0030335	2	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.015	Human Yeast
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
cell migration	GO:0016477	238	0.015
tube development	GO:0035295	244	0.015
negative regulation of catabolic process	GO:0009895	36	0.015
positive regulation of cell motility	GO:2000147	3	0.015
neuron projection guidance	GO:0097485	241	0.015
eye development	GO:0001654	323	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.015	Human Yeast
peptidyl amino acid modification	GO:0018193	105	0.015
nuclear transport	GO:0051169	72	0.015
cellular response to external stimulus	GO:0071496	66	0.015
head development	GO:0060322	135	0.015
nucleoside metabolic process	GO:0009116	127	0.015	Human Yeast
meiosis i	GO:0007127	59	0.015
positive regulation of nucleotide metabolic process	GO:0045981	55	0.015
salivary gland morphogenesis	GO:0007435	145	0.015
positive regulation of transport	GO:0051050	92	0.015
positive regulation of molecular function	GO:0044093	136	0.015
regulation of mitotic cell cycle	GO:0007346	190	0.015
spermatid development	GO:0007286	98	0.015
embryonic pattern specification	GO:0009880	174	0.015
regulation of cell shape	GO:0008360	113	0.014
cellular macromolecular complex assembly	GO:0034622	153	0.014
response to bacterium	GO:0009617	198	0.014
response to abiotic stimulus	GO:0009628	341	0.014
amine metabolic process	GO:0009308	12	0.014
mesenchymal cell differentiation	GO:0048762	1	0.014
regulation of synapse structure and activity	GO:0050803	128	0.014
carbohydrate derivative metabolic process	GO:1901135	217	0.014	Human Yeast
multi multicellular organism process	GO:0044706	123	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.014	Human Yeast
negative regulation of gene expression epigenetic	GO:0045814	77	0.014
purine containing compound catabolic process	GO:0072523	112	0.014	Human Yeast
regulation of apoptotic process	GO:0042981	130	0.014
purine nucleoside metabolic process	GO:0042278	127	0.014	Human Yeast
response to radiation	GO:0009314	155	0.014
oxoacid metabolic process	GO:0043436	103	0.014
spermatid differentiation	GO:0048515	114	0.014
chromatin silencing	GO:0006342	76	0.014
segmentation	GO:0035282	207	0.014
regulation of synaptic transmission	GO:0050804	69	0.013
posttranscriptional gene silencing by rna	GO:0035194	45	0.013
neurotransmitter secretion	GO:0007269	35	0.013
chromosome segregation	GO:0007059	157	0.013
protein phosphorylation	GO:0006468	169	0.013
regulation of establishment of protein localization	GO:0070201	61	0.013
pattern recognition receptor signaling pathway	GO:0002221	2	0.013
neurological system process	GO:0050877	358	0.013
photoreceptor cell differentiation	GO:0046530	170	0.013
mitotic spindle organization	GO:0007052	220	0.013
chromosome condensation	GO:0030261	41	0.013
purine nucleoside catabolic process	GO:0006152	112	0.013	Human Yeast
morphogenesis of a branching epithelium	GO:0061138	45	0.013
digestive system development	GO:0055123	149	0.013
regulation of mapk cascade	GO:0043408	92	0.013
regulation of intracellular protein transport	GO:0033157	46	0.013
organonitrogen compound catabolic process	GO:1901565	128	0.013	Human Yeast
cellular macromolecule catabolic process	GO:0044265	136	0.012
establishment of organelle localization	GO:0051656	122	0.012
modification dependent protein catabolic process	GO:0019941	78	0.012
regulation of microtubule based process	GO:0032886	49	0.012
organophosphate biosynthetic process	GO:0090407	46	0.012
cellular amino acid metabolic process	GO:0006520	61	0.012
gene silencing	GO:0016458	138	0.012
establishment of cell polarity	GO:0030010	40	0.012
regulation of anatomical structure size	GO:0090066	163	0.012
imaginal disc derived wing vein specification	GO:0007474	48	0.012
mesenchymal cell development	GO:0014031	1	0.012
protein processing	GO:0016485	68	0.012
protein catabolic process	GO:0030163	101	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
positive regulation of intracellular signal transduction	GO:1902533	116	0.012
muscle adaptation	GO:0043500	1	0.012
positive regulation of immune system process	GO:0002684	68	0.012
regulation of lipid transport	GO:0032368	3	0.012
dephosphorylation	GO:0016311	51	0.012
microtubule based movement	GO:0007018	51	0.012
stress activated protein kinase signaling cascade	GO:0031098	55	0.012
brain development	GO:0007420	120	0.012
single organism behavior	GO:0044708	391	0.012
multi organism reproductive behavior	GO:0044705	121	0.012
cell adhesion	GO:0007155	136	0.012
golgi vesicle transport	GO:0048193	27	0.011
negative regulation of microtubule depolymerization	GO:0007026	21	0.011
embryonic axis specification	GO:0000578	107	0.011
positive regulation of programmed cell death	GO:0043068	62	0.011
endosomal transport	GO:0016197	44	0.011	Human
regulation of neuron projection development	GO:0010975	69	0.011
regulation of organ morphogenesis	GO:2000027	78	0.011
cellular response to extracellular stimulus	GO:0031668	64	0.011
dna packaging	GO:0006323	91	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
regulation of developmental growth	GO:0048638	174	0.011
positive regulation of secretion by cell	GO:1903532	20	0.011
reproductive structure development	GO:0048608	74	0.011
neuron death	GO:0070997	27	0.011
actomyosin structure organization	GO:0031032	56	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
mushroom body development	GO:0016319	70	0.011
nucleobase containing compound catabolic process	GO:0034655	165	0.011	Human Yeast
nucleocytoplasmic transport	GO:0006913	72	0.010
small gtpase mediated signal transduction	GO:0007264	88	0.010
single organism biosynthetic process	GO:0044711	206	0.010
nucleoside phosphate catabolic process	GO:1901292	110	0.010	Human Yeast
protein k48 linked ubiquitination	GO:0070936	3	0.010
regulation of translation	GO:0006417	56	0.010
gland morphogenesis	GO:0022612	145	0.010
protein complex assembly	GO:0006461	200	0.010
developmental programmed cell death	GO:0010623	138	0.010
response to lipopolysaccharide	GO:0032496	4	0.010
nucleoside triphosphate catabolic process	GO:0009143	108	0.010	Human Yeast
tripartite regional subdivision	GO:0007351	103	0.010
negative regulation of growth	GO:0045926	84	0.010
positive regulation of nervous system development	GO:0051962	69	0.010
regulation of innate immune response	GO:0045088	71	0.010
nucleoside catabolic process	GO:0009164	112	0.010	Human Yeast
carbohydrate derivative biosynthetic process	GO:1901137	85	0.010
eye photoreceptor cell fate commitment	GO:0042706	37	0.010
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.010
regulation of wnt signaling pathway	GO:0030111	68	0.010
regulation of cytoskeleton organization	GO:0051493	89	0.010
regulation of response to biotic stimulus	GO:0002831	63	0.010
regulation of phosphorylation	GO:0042325	147	0.010

Rab35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.012
cancer	DOID:162	0.012
organ system cancer	DOID:0050686	0.012
disease of anatomical entity	DOID:7	0.010

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