Drosophila melanogaster

125 known processes

MED6 (Dmel_CG9473)

Mediator complex subunit 6

(Aliases: BcDNA:LD15729,dMed6,Dmel\CG9473,anon-EST:Posey279,dMED6,Trap32,dTRAP32,Med6,p35,CG9473)

MED6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neuroblast proliferationGO:1902692340.990
negative regulation of neuroblast proliferationGO:0007406270.988
stem cell proliferationGO:0072089880.959
negative regulation of cell cycle phase transitionGO:19019881030.955
negative regulation of neural precursor cell proliferationGO:2000178270.954
regulation of nervous system developmentGO:00519602480.921
transcription from rna polymerase ii promoterGO:00063663680.909
mitotic g2 dna damage checkpointGO:0007095690.909
regulation of multicellular organismal developmentGO:20000264140.873
mitotic dna integrity checkpointGO:0044774750.867
mitotic g2 m transition checkpointGO:0044818700.867
regulation of neural precursor cell proliferationGO:2000177350.853
mitotic cell cycle checkpointGO:0007093880.847
negative regulation of nitrogen compound metabolic processGO:00511722650.825
g2 dna damage checkpointGO:0031572690.815
negative regulation of stem cell proliferationGO:2000647300.813
regulation of stem cell proliferationGO:0072091400.802
regulation of mitotic cell cycle phase transitionGO:19019901300.797
regulation of cell cycle phase transitionGO:19019871300.786
negative regulation of cell proliferationGO:0008285690.784
regulation of transcription from rna polymerase ii promoterGO:00063573780.784
mrna polyadenylationGO:0006378110.775
cell cycle phase transitionGO:00447701400.698
mitotic dna damage checkpointGO:0044773740.688
negative regulation of multicellular organismal processGO:00512411420.680
dna integrity checkpointGO:0031570810.654
negative regulation of mitotic cell cycleGO:00459301090.622
negative regulation of nucleic acid templated transcriptionGO:19035072400.602
negative regulation of cell cycle processGO:00109481090.546
negative regulation of cell differentiationGO:00455961430.539
cell cycle checkpointGO:0000075950.537
negative regulation of biosynthetic processGO:00098902770.524
sex comb developmentGO:004549880.518
negative regulation of cell cycleGO:00457861160.517
negative regulation of nervous system developmentGO:0051961920.513
dna damage checkpointGO:0000077780.487
cell proliferationGO:00082832990.487
neuroblast proliferationGO:0007405740.485
regulation of neurogenesisGO:00507671580.484
regulation of cell developmentGO:00602842150.472
negative regulation of mitotic cell cycle phase transitionGO:19019911030.461
segmentationGO:00352822070.436
negative regulation of neurogenesisGO:0050768530.415
negative regulation of cell developmentGO:0010721620.413
regulation of cell cycleGO:00517262910.402
mitotic cell cycle phase transitionGO:00447721380.377
cullin deneddylationGO:001038830.368
negative regulation of cellular metabolic processGO:00313243820.363
positive regulation of rna metabolic processGO:00512542710.347
Human
columnar cuboidal epithelial cell developmentGO:00020662490.347
developmental growthGO:00485892800.320
organic substance transportGO:00717022570.280
protein transportGO:00150311550.275
embryo development ending in birth or egg hatchingGO:00097921520.266
Worm
positive regulation of nucleic acid templated transcriptionGO:19035082660.261
Human
regulation of cell differentiationGO:00455953020.258
regulation of cell proliferationGO:00421271630.257
rna polyadenylationGO:0043631120.255
negative regulation of gene expressionGO:00106293870.254
nuclear divisionGO:00002803320.253
regulation of cellular component biogenesisGO:00440872010.246
growthGO:00400073590.243
establishment of protein localizationGO:00451841630.239
histolysisGO:00075591020.232
negative regulation of rna biosynthetic processGO:19026792400.232
response to biotic stimulusGO:00096072940.229
oocyte developmentGO:00485991240.226
response to bacteriumGO:00096171980.222
negative regulation of macromolecule biosynthetic processGO:00105582700.171
regulation of mitotic cell cycleGO:00073461900.162
photoreceptor cell differentiationGO:00465301700.152
gene silencing by rnaGO:0031047570.149
gene silencingGO:00164581380.146
mrna metabolic processGO:00160711240.146
organelle fissionGO:00482853400.136
cellular protein localizationGO:00346131600.132
positive regulation of transcription dna templatedGO:00458932660.132
Human
protein modification by small protein conjugationGO:0032446790.130
negative regulation of nucleobase containing compound metabolic processGO:00459342610.127
oocyte differentiationGO:00099941450.126
axon developmentGO:00615642970.125
neural precursor cell proliferationGO:0061351750.123
cellular macromolecule catabolic processGO:00442651360.120
oocyte constructionGO:00073081120.118
positive regulation of biosynthetic processGO:00098913160.116
Human
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.115
histone methylationGO:0016571400.110
heterochromatin organizationGO:0070828250.105
sex differentiationGO:0007548810.104
Worm
macromolecule methylationGO:0043414450.102
rna processingGO:00063961470.101
macromolecule catabolic processGO:00090571610.097
negative regulation of transcription dna templatedGO:00458922370.096
imaginal disc derived leg segmentationGO:0036011260.095
appendage segmentationGO:0035285260.095
histone lysine methylationGO:0034968320.094
regulation of cellular localizationGO:00603411360.091
response to ecdysoneGO:0035075340.090
cellular response to ketoneGO:1901655170.086
eye photoreceptor cell differentiationGO:00017541450.086
endomembrane system organizationGO:00102561190.084
developmental programmed cell deathGO:00106231380.082
cellular response to chemical stimulusGO:00708871990.082
regulation of notch signaling pathwayGO:00085931000.081
enzyme linked receptor protein signaling pathwayGO:00071671790.080
regulation of growthGO:00400082330.080
eye morphogenesisGO:00485922600.078
protein deneddylationGO:000033880.078
ovarian follicle cell developmentGO:00307072480.077
cell maturationGO:00484691440.077
secretion by cellGO:00329401010.076
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.075
Human
taxisGO:00423303040.072
salivary gland histolysisGO:0035070880.071
response to organic cyclic compoundGO:0014070890.068
regulation of transportGO:00510491810.068
cell motilityGO:00488702510.068
dna templated transcription initiationGO:0006352250.067
negative regulation of cellular biosynthetic processGO:00313272770.066
negative regulation of developmental processGO:00510932010.066
establishment or maintenance of cell polarityGO:00071631670.065
stem cell differentiationGO:00488631170.063
g1 s transition of mitotic cell cycleGO:0000082310.062
positive regulation of gene expressionGO:00106282900.062
Human
cellular response to uvGO:0034644120.061
negative regulation of cell communicationGO:00106482230.061
positive regulation of nucleobase containing compound metabolic processGO:00459353320.061
Human
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.059
epithelium migrationGO:00901321480.057
response to abiotic stimulusGO:00096283410.057
protein modification by small protein conjugation or removalGO:00706471060.057
gland developmentGO:00487321910.056
protein modification processGO:00362114380.056
compound eye morphogenesisGO:00017452490.056
organic substance catabolic processGO:19015753080.055
regulation of immune responseGO:00507761180.055
response to endogenous stimulusGO:00097191190.055
cellular macromolecule localizationGO:00707272200.054
salivary gland cell autophagic cell deathGO:0035071830.053
cell migrationGO:00164772380.052
mrna processingGO:00063971040.051
regulation of developmental growthGO:00486381740.051
intracellular transportGO:00469072280.050
oocyte axis specificationGO:00073091080.050
regulation of immune system processGO:00026821760.049
muscle organ developmentGO:00075171270.048
protein localizationGO:00081042840.047
regulation of gene expression epigeneticGO:00400291280.045
regulation of intracellular transportGO:0032386640.044
sensory organ morphogenesisGO:00905962600.044
cell divisionGO:00513012480.043
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.043
phosphorylation of rna polymerase ii c terminal domainGO:007081610.042
autophagic cell deathGO:0048102830.042
cellular response to organonitrogen compoundGO:0071417360.041
cytoplasmic transportGO:00164821300.041
transcription initiation from rna polymerase ii promoterGO:0006367250.040
appendage developmentGO:00487364010.040
compound eye photoreceptor cell differentiationGO:00017511400.040
protein alkylationGO:0008213430.040
protein modification by small protein removalGO:0070646280.039
cell cycle g1 s phase transitionGO:0044843310.039
positive regulation of rna biosynthetic processGO:19026802660.038
Human
developmental maturationGO:00217001720.038
epithelial cell developmentGO:00020642740.038
response to sterolGO:0036314340.038
positive regulation of macromolecule metabolic processGO:00106044050.037
Human
response to organonitrogen compoundGO:0010243750.037
positive regulation of developmental processGO:00510941430.037
imaginal disc growthGO:0007446370.036
cellular response to organic substanceGO:00713101320.036
proteolysisGO:00065081920.036
macromolecular complex assemblyGO:00650032560.036
regionalizationGO:00030024160.036
single organism intracellular transportGO:19025822070.036
ameboidal type cell migrationGO:00016671510.035
negative regulation of signal transductionGO:00099682060.035
tissue deathGO:00162711020.034
negative regulation of signalingGO:00230572190.033
positive regulation of cellular biosynthetic processGO:00313283160.033
Human
cellular protein modification processGO:00064644380.033
negative regulation of response to stimulusGO:00485852580.033
regulation of localizationGO:00328792750.033
dendrite developmentGO:00163582040.033
central nervous system developmentGO:00074172010.033
detection of external stimulusGO:0009581660.032
mitotic nuclear divisionGO:00070672130.032
establishment of localization in cellGO:00516494020.032
meiosis iGO:0007127590.032
methylationGO:0032259470.032
tissue morphogenesisGO:00487292970.031
axon guidanceGO:00074112330.031
positive regulation of developmental growthGO:0048639620.029
jak stat cascadeGO:0007259490.029
oocyte microtubule cytoskeleton polarizationGO:0008103220.029
chaeta developmentGO:0022416970.029
axis specificationGO:00097981670.028
intracellular steroid hormone receptor signaling pathwayGO:0030518120.028
compound eye developmentGO:00487493070.028
lateral inhibitionGO:00463312060.028
localization of cellGO:00516742570.028
rna 3 end processingGO:0031123450.027
nuclear importGO:0051170510.027
ncrna metabolic processGO:0034660430.027
protein ubiquitinationGO:0016567700.026
phosphorylationGO:00163102940.026
ovipositionGO:0018991190.026
neuromuscular junction developmentGO:00075281490.025
wnt signaling pathwayGO:0016055980.025
histone h2a ubiquitinationGO:003352220.025
regulation of cellular protein metabolic processGO:00322682430.025
columnar cuboidal epithelial cell differentiationGO:00020652560.025
posttranscriptional regulation of gene expressionGO:00106081450.025
regulation of multi organism processGO:00439001310.025
eggshell chorion gene amplificationGO:000730790.025
positive regulation of cell communicationGO:00106472500.025
muscle structure developmentGO:00610612240.025
regulation of wnt signaling pathwayGO:0030111680.024
epithelial cell differentiationGO:00308553220.024
imaginal disc derived appendage morphogenesisGO:00351143950.024
sister chromatid segregationGO:0000819920.024
morphogenesis of follicular epitheliumGO:0016333360.024
epidermis developmentGO:0008544650.024
immune responseGO:00069552460.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
Human
cellular response to light stimulusGO:0071482370.023
appendage morphogenesisGO:00351073970.023
regulation of protein modification processGO:00313991120.023
salivary gland developmentGO:00074311620.023
centrosome cycleGO:00070981370.022
peptidyl amino acid modificationGO:00181931050.022
single organism cellular localizationGO:19025801800.022
embryonic pattern specificationGO:00098801740.021
cellular response to radiationGO:0071478520.021
tissue migrationGO:00901301550.021
salivary gland morphogenesisGO:00074351450.021
ovarian follicle cell migrationGO:00072971210.021
response to organic substanceGO:00100332840.021
mitotic sister chromatid cohesionGO:000706460.020
response to ketoneGO:1901654340.020
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.020
stem cell maintenanceGO:0019827670.020
proteolysis involved in cellular protein catabolic processGO:0051603830.020
membrane organizationGO:00610241120.020
response to other organismGO:00517072930.020
leg disc morphogenesisGO:0007478800.020
protein catabolic processGO:00301631010.020
morphogenesis of an epitheliumGO:00020092760.020
secretionGO:00469031090.020
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.019
pole plasm assemblyGO:0007315610.019
regulation of circadian rhythmGO:0042752490.019
ubiquitin dependent protein catabolic processGO:0006511780.019
regulation of epithelial cell differentiationGO:003085640.019
defense response to bacteriumGO:00427421780.019
cellular response to abiotic stimulusGO:0071214580.019
cardiovascular system developmentGO:0072358820.019
nucleosome mobilizationGO:004276690.019
nucleosome positioningGO:001658430.019
regulation of cytoplasmic transportGO:1903649470.019
cellular response to endogenous stimulusGO:0071495800.018
dorsal ventral axis specificationGO:0009950660.018
regulation of protein catabolic processGO:0042176550.018
chromosome organization involved in meiosisGO:0070192100.018
nuclear transportGO:0051169720.018
regulation of innate immune responseGO:0045088710.018
endocytosisGO:00068973100.018
striated muscle myosin thick filament assemblyGO:007168830.017
reproductive system developmentGO:0061458740.017
Worm
chromosome segregationGO:00070591570.017
dna alkylationGO:000630540.017
negative regulation of rna metabolic processGO:00512532510.017
neuron remodelingGO:0016322290.017
organelle assemblyGO:00709251980.017
epithelial cell migrationGO:00106311480.017
regulation of embryonic developmentGO:0045995680.016
cellular response to oxygen containing compoundGO:1901701790.016
regulation of cellular component sizeGO:0032535980.016
lipid storageGO:0019915380.016
regulation of protein stabilityGO:0031647430.016
protein methylationGO:0006479430.016
mrna 3 end processingGO:0031124280.016
axonogenesisGO:00074092900.016
stem cell developmentGO:0048864790.016
blastoderm segmentationGO:00073501590.016
eye photoreceptor cell developmentGO:0042462810.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
Human
defense response to gram negative bacteriumGO:0050829940.015
dna methylation or demethylationGO:004472840.015
protein phosphorylationGO:00064681690.015
tripartite regional subdivisionGO:00073511030.015
nephron developmentGO:007200630.015
anatomical structure homeostasisGO:0060249970.015
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.015
modification dependent protein catabolic processGO:0019941780.015
posttranscriptional gene silencing by rnaGO:0035194450.015
mitotic cell cycle embryonicGO:0045448380.015
multicellular organismal reproductive behaviorGO:00330571100.015
response to oxygen containing compoundGO:19017002000.014
positive regulation of notch signaling pathwayGO:0045747340.014
regulation of cellular amine metabolic processGO:003323830.014
deathGO:00162652840.014
reproductive structure developmentGO:0048608740.014
Worm
eggshell formationGO:00307031050.014
chromatin modificationGO:00165681470.013
development of primary sexual characteristicsGO:0045137500.013
Worm
generation of precursor metabolites and energyGO:0006091420.013
posttranscriptional gene silencingGO:0016441460.013
imaginal disc derived appendage developmentGO:00487373990.013
ecdysone receptor mediated signaling pathwayGO:0035076110.013
intracellular receptor signaling pathwayGO:0030522190.013
positive regulation of neurogenesisGO:0050769410.012
regulation of protein transportGO:0051223570.012
response to alcoholGO:0097305950.012
asymmetric cell divisionGO:0008356370.012
cellular catabolic processGO:00442483720.012
pigmentationGO:0043473750.012
neuron projection guidanceGO:00974852410.012
positive regulation of signalingGO:00230562430.012
programmed cell deathGO:00125012570.012
negative regulation of cellular protein metabolic processGO:0032269850.012
organonitrogen compound metabolic processGO:19015643180.012
regulation of epidermal cell differentiationGO:004560430.012
chemotaxisGO:00069352490.012
small molecule metabolic processGO:00442813050.012
response to peptideGO:1901652290.012
regulation of neuron differentiationGO:00456641030.012
response to external biotic stimulusGO:00432072930.012
protein targeting to nucleusGO:0044744510.011
phagocytosisGO:00069092150.011
chromatin organizationGO:00063252070.011
protein localization to nucleusGO:0034504550.011
anterior posterior axis specification embryoGO:00085951030.011
mrna splicing via spliceosomeGO:0000398730.011
eye developmentGO:00016543230.011
anterior posterior pattern specificationGO:00099521360.011
morphogenesis of a polarized epitheliumGO:0001738930.011
peptidyl tyrosine modificationGO:0018212240.011
negative regulation of epithelial cell proliferationGO:005068040.011
cellular response to organic cyclic compoundGO:0071407320.011
cellular response to ecdysoneGO:0071390170.011
organ growthGO:0035265560.011
cellular response to nitrogen compoundGO:1901699510.011
protein secretionGO:0009306450.011
eggshell chorion assemblyGO:0007306660.011
sister chromatid cohesionGO:0007062180.011
regulation of epithelial cell proliferationGO:005067840.010
dorsal ventral pattern formationGO:00099531330.010
regulation of cell sizeGO:0008361630.010
nucleocytoplasmic transportGO:0006913720.010
homeostatic processGO:00425921990.010

MED6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.086
cancerDOID:16200.086
disease of anatomical entityDOID:700.069
organ system cancerDOID:005068600.027