Drosophila melanogaster

26 known processes

Sym (Dmel_CG2097)

Symplekin

(Aliases: Dmel\CG2097,CG2097,dSymp)

Sym biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of macromolecule metabolic processGO:00106044050.413
transcription from rna polymerase ii promoterGO:00063663680.397
positive regulation of nitrogen compound metabolic processGO:00511733540.384
positive regulation of nucleobase containing compound metabolic processGO:00459353320.319
regulation of transcription from rna polymerase ii promoterGO:00063573780.298
catabolic processGO:00090564090.275
intracellular transportGO:00469072280.226
intracellular signal transductionGO:00355563000.209
cellular response to dna damage stimulusGO:00069742230.207
cellular catabolic processGO:00442483720.199
positive regulation of nucleic acid templated transcriptionGO:19035082660.189
rna processingGO:00063961470.185
positive regulation of rna biosynthetic processGO:19026802660.177
regulation of phosphorus metabolic processGO:00511742100.168
negative regulation of gene expressionGO:00106293870.163
positive regulation of phosphate metabolic processGO:00459371390.159
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.157
positive regulation of gene expressionGO:00106282900.157
chromosome organizationGO:00512763600.156
positive regulation of macromolecule biosynthetic processGO:00105572830.138
organic substance catabolic processGO:19015753080.134
regulation of cell differentiationGO:00455953020.116
positive regulation of phosphorus metabolic processGO:00105621390.110
positive regulation of cellular biosynthetic processGO:00313283160.110
cellular protein modification processGO:00064644380.104
cellular protein localizationGO:00346131600.102
dna metabolic processGO:00062592270.101
cellular macromolecule localizationGO:00707272200.098
protein localizationGO:00081042840.093
regulation of cellular protein metabolic processGO:00322682430.093
small molecule metabolic processGO:00442813050.089
tissue morphogenesisGO:00487292970.085
negative regulation of nucleic acid templated transcriptionGO:19035072400.085
epithelial cell differentiationGO:00308553220.085
wing disc morphogenesisGO:00074723440.084
negative regulation of nitrogen compound metabolic processGO:00511722650.084
defense responseGO:00069523000.081
response to external biotic stimulusGO:00432072930.081
positive regulation of signal transductionGO:00099672230.080
regulation of phosphate metabolic processGO:00192202100.080
cell migrationGO:00164772380.079
Worm
protein catabolic processGO:00301631010.078
positive regulation of cell communicationGO:00106472500.076
regulation of catabolic processGO:00098941700.075
establishment of localization in cellGO:00516494020.073
regulation of molecular functionGO:00650092170.073
dna repairGO:0006281540.072
phosphorylationGO:00163102940.071
modification dependent macromolecule catabolic processGO:0043632790.071
segmentationGO:00352822070.071
proteolysisGO:00065081920.070
positive regulation of transcription dna templatedGO:00458932660.069
carbohydrate derivative metabolic processGO:19011352170.069
negative regulation of macromolecule biosynthetic processGO:00105582700.068
cytoplasmic transportGO:00164821300.067
regulation of cell cycle processGO:00105641810.067
positive regulation of response to stimulusGO:00485843230.067
regulation of intracellular signal transductionGO:19025312360.067
ubiquitin dependent protein catabolic processGO:0006511780.066
defense response to other organismGO:00985422250.064
purine nucleotide catabolic processGO:00061951090.063
single organism cellular localizationGO:19025801800.063
embryo development ending in birth or egg hatchingGO:00097921520.062
Worm
sister chromatid segregationGO:0000819920.061
macromolecule catabolic processGO:00090571610.061
nucleotide catabolic processGO:00091661090.059
regulation of immune system processGO:00026821760.057
purine containing compound catabolic processGO:00725231120.056
small gtpase mediated signal transductionGO:0007264880.056
cellular nitrogen compound catabolic processGO:00442701650.056
snrna 3 end processingGO:0034472140.055
immune system processGO:00023763470.054
positive regulation of biosynthetic processGO:00098913160.054
response to light stimulusGO:00094161240.052
enzyme linked receptor protein signaling pathwayGO:00071671790.052
mitotic nuclear divisionGO:00070672130.052
protein transportGO:00150311550.052
epithelial cell developmentGO:00020642740.051
chromatin modificationGO:00165681470.051
regulation of multicellular organismal developmentGO:20000264140.051
cellular response to lipopolysaccharideGO:007122230.050
regulation of cellular amino acid metabolic processGO:000652100.050
response to abiotic stimulusGO:00096283410.049
purine ribonucleoside catabolic processGO:00461301120.049
microtubule organizing center organizationGO:00310231680.048
purine nucleoside metabolic processGO:00422781270.048
protein modification processGO:00362114380.047
dna damage checkpointGO:0000077780.047
regionalizationGO:00030024160.047
nucleoside catabolic processGO:00091641120.046
ribonucleoside catabolic processGO:00424541120.046
regulation of protein metabolic processGO:00512462560.046
organic substance transportGO:00717022570.045
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.045
regulation of localizationGO:00328792750.044
morphogenesis of an epitheliumGO:00020092760.044
negative regulation of nucleobase containing compound metabolic processGO:00459342610.044
positive regulation of cellular protein metabolic processGO:00322701180.044
nucleoside triphosphate catabolic processGO:00091431080.043
regulation of catalytic activityGO:00507901850.042
glycosyl compound catabolic processGO:19016581120.042
negative regulation of response to stimulusGO:00485852580.042
negative regulation of rna biosynthetic processGO:19026792400.041
organelle fissionGO:00482853400.041
nucleoside triphosphate metabolic processGO:00091411200.040
ribonucleotide catabolic processGO:00092611090.040
protein localization to organelleGO:0033365820.040
single organism catabolic processGO:00447122280.040
purine ribonucleoside metabolic processGO:00461281270.040
regulation of phosphorylationGO:00423251470.039
eye morphogenesisGO:00485922600.039
positive regulation of signalingGO:00230562430.039
regulation of cellular component sizeGO:0032535980.039
regulation of small gtpase mediated signal transductionGO:0051056930.039
purine nucleoside catabolic processGO:00061521120.038
regulation of cell cycleGO:00517262910.038
ras protein signal transductionGO:0007265880.038
cellular macromolecule catabolic processGO:00442651360.038
glycosyl compound metabolic processGO:19016571270.038
ncrna 3 end processingGO:0043628170.038
protein import into nucleusGO:0006606510.037
intracellular protein transportGO:00068861040.037
purine containing compound metabolic processGO:00725211550.037
single organism nuclear importGO:1902593510.035
positive regulation of catabolic processGO:00098961050.035
purine nucleoside triphosphate catabolic processGO:00091461080.034
centrosome organizationGO:00512971630.033
organophosphate metabolic processGO:00196371950.032
regulation of cellular ketone metabolic processGO:001056530.032
positive regulation of catalytic activityGO:00430851180.032
response to biotic stimulusGO:00096072940.032
nuclear divisionGO:00002803320.032
negative regulation of transcription dna templatedGO:00458922370.032
response to lipopolysaccharideGO:003249640.032
protein phosphorylationGO:00064681690.031
carbohydrate derivative catabolic processGO:19011361180.031
response to bacteriumGO:00096171980.031
positive regulation of intracellular signal transductionGO:19025331160.030
body morphogenesisGO:001017120.030
nucleobase containing compound catabolic processGO:00346551650.030
purine nucleoside triphosphate metabolic processGO:00091441190.029
positive regulation of protein metabolic processGO:00512471280.029
purine ribonucleotide catabolic processGO:00091541090.029
g protein coupled receptor signaling pathwayGO:00071861360.029
gtp catabolic processGO:0006184720.029
proteolysis involved in cellular protein catabolic processGO:0051603830.028
regulation of protein localizationGO:0032880760.028
negative regulation of cell cycle phase transitionGO:19019881030.028
regulation of cellular catabolic processGO:00313291570.028
modification dependent protein catabolic processGO:0019941780.027
innate immune responseGO:00450871440.027
protein targeting to nucleusGO:0044744510.027
cellular macromolecular complex assemblyGO:00346221530.027
guanosine containing compound metabolic processGO:1901068740.026
establishment of protein localizationGO:00451841630.026
homeostatic processGO:00425921990.026
negative regulation of biosynthetic processGO:00098902770.026
axon developmentGO:00615642970.025
ncrna metabolic processGO:0034660430.025
organonitrogen compound metabolic processGO:19015643180.025
response to radiationGO:00093141550.025
purine ribonucleoside triphosphate metabolic processGO:00092051190.025
positive regulation of phosphorylationGO:0042327870.025
nuclear importGO:0051170510.024
heterocycle catabolic processGO:00467001660.024
purine nucleotide metabolic processGO:00061631460.024
axonogenesisGO:00074092900.024
double strand break repairGO:0006302260.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
appendage morphogenesisGO:00351073970.023
anterior posterior axis specificationGO:00099481090.023
establishment of protein localization to organelleGO:0072594620.023
positive regulation of molecular functionGO:00440931360.023
appendage developmentGO:00487364010.023
regulation of cellular amine metabolic processGO:003323830.023
mitotic sister chromatid segregationGO:0000070870.023
single organism intracellular transportGO:19025822070.023
nucleoside phosphate catabolic processGO:19012921100.023
nuclear transportGO:0051169720.023
organonitrogen compound catabolic processGO:19015651280.022
purine ribonucleoside triphosphate catabolic processGO:00092071080.022
proteasomal protein catabolic processGO:0010498590.022
cellular amino acid metabolic processGO:0006520610.022
positive regulation of multicellular organismal processGO:00512401430.022
protein importGO:0017038550.022
regulation of gene expression epigeneticGO:00400291280.022
apoptotic processGO:00069151590.022
positive regulation of hydrolase activityGO:0051345780.021
mitotic cell cycle phase transitionGO:00447721380.021
gtp metabolic processGO:0046039720.021
histone h3 k4 methylationGO:0051568160.021
ribonucleotide metabolic processGO:00092591450.021
dna integrity checkpointGO:0031570810.021
oxoacid metabolic processGO:00434361030.021
cellular response to chemical stimulusGO:00708871990.021
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.021
cellular protein complex assemblyGO:0043623710.020
imaginal disc derived wing morphogenesisGO:00074763370.020
regulation of hydrolase activityGO:0051336970.020
mitotic g2 dna damage checkpointGO:0007095690.020
protein localization to nucleusGO:0034504550.020
ribose phosphate metabolic processGO:00196931450.020
nucleoside metabolic processGO:00091161270.020
chromatin organizationGO:00063252070.020
positive regulation of protein modification processGO:0031401580.020
regulation of cellular component biogenesisGO:00440872010.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.019
posttranscriptional gene silencingGO:0016441460.019
stem cell differentiationGO:00488631170.019
nucleotide metabolic processGO:00091171610.019
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.019
regulation of nucleotide metabolic processGO:0006140620.019
pole cell formationGO:0007279190.019
cellular protein catabolic processGO:0044257830.019
ovarian follicle cell developmentGO:00307072480.019
negative regulation of rna metabolic processGO:00512532510.019
organic cyclic compound catabolic processGO:19013611680.018
negative regulation of cell communicationGO:00106482230.018
positive regulation of nucleocytoplasmic transportGO:0046824240.018
nucleobase containing small molecule metabolic processGO:00550861740.018
positive regulation of organelle organizationGO:0010638650.018
regulation of cellular localizationGO:00603411360.018
negative regulation of cell cycleGO:00457861160.018
purine ribonucleotide metabolic processGO:00091501450.018
ribonucleoside triphosphate catabolic processGO:00092031080.017
protein ubiquitinationGO:0016567700.017
regulation of programmed cell deathGO:00430671520.017
protein complex biogenesisGO:00702712010.017
aromatic compound catabolic processGO:00194391660.017
nitrogen compound transportGO:0071705850.017
mitotic g2 m transition checkpointGO:0044818700.017
mitotic dna integrity checkpointGO:0044774750.016
organophosphate catabolic processGO:00464341120.016
nucleocytoplasmic transportGO:0006913720.016
nucleoside phosphate metabolic processGO:00067531620.016
negative regulation of cellular metabolic processGO:00313243820.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.016
regulation of apoptotic processGO:00429811300.016
regulation of ras protein signal transductionGO:0046578930.016
guanosine containing compound catabolic processGO:1901069740.016
nuclear pore organizationGO:000699910.016
protein modification by small protein conjugation or removalGO:00706471060.016
chemotaxisGO:00069352490.016
ribonucleoside metabolic processGO:00091191270.016
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
regulation of protein phosphorylationGO:0001932640.015
regulation of cytoplasmic transportGO:1903649470.015
regulation of mitotic cell cycleGO:00073461900.015
regulation of transferase activityGO:0051338580.015
cell fate determinationGO:0001709910.014
single organism biosynthetic processGO:00447112060.014
photoreceptor cell differentiationGO:00465301700.014
response to other organismGO:00517072930.014
carboxylic acid metabolic processGO:0019752920.014
cell maturationGO:00484691440.014
nucleus organizationGO:0006997450.014
regulation of chromosome organizationGO:0033044640.014
cellular response to organic substanceGO:00713101320.014
regulation of protein modification processGO:00313991120.014
positive regulation of cellular amine metabolic processGO:003324000.014
gene silencingGO:00164581380.014
axis specificationGO:00097981670.014
taxisGO:00423303040.014
regulation of protein catabolic processGO:0042176550.014
negative regulation of developmental processGO:00510932010.014
gland morphogenesisGO:00226121450.013
mitotic cell cycle checkpointGO:0007093880.013
regulation of immune effector processGO:0002697520.013
protein modification by small protein conjugationGO:0032446790.013
response to nitrogen compoundGO:1901698900.013
multicellular organismal agingGO:00102591400.013
Worm
regulation of establishment of protein localizationGO:0070201610.012
macromolecule methylationGO:0043414450.012
cell motilityGO:00488702510.012
Worm
cellular amine metabolic processGO:0044106120.012
mapk cascadeGO:00001651070.012
response to organic substanceGO:00100332840.012
jak stat cascadeGO:0007259490.012
stem cell maintenanceGO:0019827670.012
salivary gland developmentGO:00074311620.012
negative regulation of cellular biosynthetic processGO:00313272770.012
regulation of kinase activityGO:0043549530.012
cellular ketone metabolic processGO:0042180240.012
regulation of cell sizeGO:0008361630.012
negative regulation of signal transductionGO:00099682060.012
exocrine system developmentGO:00352721620.012
circulatory system processGO:0003013370.012
protein targetingGO:0006605640.012
regulation of defense responseGO:00313471020.012
gland developmentGO:00487321910.012
macromolecular complex assemblyGO:00650032560.012
negative regulation of cell differentiationGO:00455961430.011
amine metabolic processGO:0009308120.011
regulation of purine nucleotide catabolic processGO:0033121480.011
nucleobase containing compound transportGO:0015931560.011
imaginal disc derived appendage developmentGO:00487373990.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
regulation of organelle organizationGO:00330431960.011
cellular response to nitrogen compoundGO:1901699510.011
agingGO:00075681430.011
Worm
dna packagingGO:0006323910.011
positive regulation of cellular component organizationGO:00511301560.011
signal transduction by phosphorylationGO:00230141070.011
establishment of tissue polarityGO:0007164870.011
autophagic cell deathGO:0048102830.011
regulation of protein kinase activityGO:0045859510.011
regulation of developmental growthGO:00486381740.011
salivary gland morphogenesisGO:00074351450.010
regulation of multi organism processGO:00439001310.010
regulation of protein localization to nucleusGO:1900180290.010
regulation of nucleoside metabolic processGO:0009118500.010

Sym disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.011