IMP: Integrative Multi-species Prediction

Drosophila melanogaster

39 known processes

Art1 (Dmel_CG6554)

Arginine methyltransferase 1

(Aliases: CG6554,Dmel\CG6554,DART1)

FLYBASE: FBgn0037834
Entrez: 41295
UniProtKB: Q9VGW7

Process Predictions
Disease Predictions

Art1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic cell cycle phase transition	GO:0044772	138	0.547
negative regulation of cell cycle phase transition	GO:1901988	103	0.468
regulation of mitotic cell cycle	GO:0007346	190	0.440
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.356
cell cycle phase transition	GO:0044770	140	0.341
muscle structure development	GO:0061061	224	0.290	Worm
mitotic g2 m transition checkpoint	GO:0044818	70	0.270
regulation of cell cycle	GO:0051726	291	0.270
death	GO:0016265	284	0.264
negative regulation of cell cycle process	GO:0010948	109	0.259
macromolecular complex assembly	GO:0065003	256	0.256	Worm
regulation of cellular protein metabolic process	GO:0032268	243	0.195
regulation of cell cycle phase transition	GO:1901987	130	0.190
nuclear division	GO:0000280	332	0.181
apoptotic process	GO:0006915	159	0.168
mitotic dna damage checkpoint	GO:0044773	74	0.168
dna damage checkpoint	GO:0000077	78	0.162
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.144
negative regulation of cell cycle	GO:0045786	116	0.139
negative regulation of mitotic cell cycle	GO:0045930	109	0.139
protein modification process	GO:0036211	438	0.122
posttranscriptional regulation of gene expression	GO:0010608	145	0.120
mitotic cell cycle checkpoint	GO:0007093	88	0.119
response to external biotic stimulus	GO:0043207	293	0.114
programmed cell death	GO:0012501	257	0.113
dna integrity checkpoint	GO:0031570	81	0.110
negative regulation of gene expression	GO:0010629	387	0.106
regulation of cell cycle process	GO:0010564	181	0.103
cell cycle checkpoint	GO:0000075	95	0.093
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.093
mitotic dna integrity checkpoint	GO:0044774	75	0.086
response to other organism	GO:0051707	293	0.085
organelle fission	GO:0048285	340	0.083
response to bacterium	GO:0009617	198	0.083
mitotic g2 dna damage checkpoint	GO:0007095	69	0.081
positive regulation of macromolecule metabolic process	GO:0010604	405	0.078
response to biotic stimulus	GO:0009607	294	0.078
protein maturation	GO:0051604	71	0.070
regulation of catabolic process	GO:0009894	170	0.070
reproductive structure development	GO:0048608	74	0.067
protein dna complex subunit organization	GO:0071824	86	0.064
reproductive system development	GO:0061458	74	0.062
cell division	GO:0051301	248	0.059
regulation of protein metabolic process	GO:0051246	256	0.058
heterocycle catabolic process	GO:0046700	166	0.058
positive regulation of cell communication	GO:0010647	250	0.058
cellular protein modification process	GO:0006464	438	0.058
development of primary sexual characteristics	GO:0045137	50	0.057
cellular macromolecular complex assembly	GO:0034622	153	0.055	Worm
macromolecule catabolic process	GO:0009057	161	0.054
protein complex biogenesis	GO:0070271	201	0.054	Worm
cellular response to dna damage stimulus	GO:0006974	223	0.054
cell death	GO:0008219	279	0.053
regulation of cellular catabolic process	GO:0031329	157	0.052
defense response to bacterium	GO:0042742	178	0.051
mitotic nuclear division	GO:0007067	213	0.051
cell proliferation	GO:0008283	299	0.050
negative regulation of response to stimulus	GO:0048585	258	0.049
meiotic cell cycle	GO:0051321	171	0.047
transcription from rna polymerase ii promoter	GO:0006366	368	0.047
organic substance catabolic process	GO:1901575	308	0.046
gonad development	GO:0008406	50	0.045
defense response	GO:0006952	300	0.045
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.044
negative regulation of cellular protein metabolic process	GO:0032269	85	0.044
localization of cell	GO:0051674	257	0.043
endocytosis	GO:0006897	310	0.042
protein localization	GO:0008104	284	0.041
growth	GO:0040007	359	0.039
larval development	GO:0002164	104	0.038
ribonucleoprotein complex biogenesis	GO:0022613	31	0.038
regionalization	GO:0003002	416	0.037
regulation of molecular function	GO:0065009	217	0.036
nuclear transport	GO:0051169	72	0.036
regulation of cell death	GO:0010941	173	0.035
protein complex assembly	GO:0006461	200	0.033	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.033	Mouse
positive regulation of gene expression	GO:0010628	290	0.033
meiotic nuclear division	GO:0007126	151	0.033
peptidyl amino acid modification	GO:0018193	105	0.033
negative regulation of protein metabolic process	GO:0051248	85	0.033
oviposition	GO:0018991	19	0.032
cellular macromolecule catabolic process	GO:0044265	136	0.032
immune system process	GO:0002376	347	0.032	Human
rna processing	GO:0006396	147	0.032
regulation of proteolysis	GO:0030162	87	0.032
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.032
positive regulation of biosynthetic process	GO:0009891	316	0.031
positive regulation of cellular biosynthetic process	GO:0031328	316	0.031
positive regulation of growth	GO:0045927	75	0.029
negative regulation of cellular catabolic process	GO:0031330	34	0.029
posttranscriptional gene silencing	GO:0016441	46	0.029
protein ubiquitination	GO:0016567	70	0.028
regulation of catalytic activity	GO:0050790	185	0.028
reproductive behavior	GO:0019098	122	0.027
sex differentiation	GO:0007548	81	0.026
regulation of cell differentiation	GO:0045595	302	0.025	Human
regulation of proteasomal protein catabolic process	GO:0061136	39	0.025
positive regulation of response to stimulus	GO:0048584	323	0.025
organelle assembly	GO:0070925	198	0.025	Worm
regulation of multicellular organismal development	GO:2000026	414	0.024	Human
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.024
phosphorylation	GO:0016310	294	0.024
cellular catabolic process	GO:0044248	372	0.024
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.023
intracellular signal transduction	GO:0035556	300	0.022
organonitrogen compound metabolic process	GO:1901564	318	0.022
cell motility	GO:0048870	251	0.022
catabolic process	GO:0009056	409	0.022
regulation of cellular ketone metabolic process	GO:0010565	3	0.022
mrna metabolic process	GO:0016071	124	0.022
protein import into nucleus	GO:0006606	51	0.022
cellular response to nutrient	GO:0031670	1	0.021
phagocytosis	GO:0006909	215	0.021
negative regulation of cell death	GO:0060548	81	0.021
g2 dna damage checkpoint	GO:0031572	69	0.020
protein processing	GO:0016485	68	0.020
developmental growth	GO:0048589	280	0.020
negative regulation of signal transduction	GO:0009968	206	0.020
cellular amino acid metabolic process	GO:0006520	61	0.020
ovarian follicle cell cell adhesion	GO:0007299	4	0.019
establishment of localization in cell	GO:0051649	402	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.019
regulation of gene expression epigenetic	GO:0040029	128	0.018
nucleocytoplasmic transport	GO:0006913	72	0.018
chromatin organization	GO:0006325	207	0.018
nucleobase containing compound catabolic process	GO:0034655	165	0.018
negative regulation of programmed cell death	GO:0043069	72	0.018
regulation of cellular protein catabolic process	GO:1903362	44	0.018
protein modification by small protein conjugation or removal	GO:0070647	106	0.017
multicellular organismal reproductive behavior	GO:0033057	110	0.017
cellular macromolecule localization	GO:0070727	220	0.017
negative regulation of biosynthetic process	GO:0009890	277	0.017
regulation of response to stress	GO:0080134	200	0.017
gene silencing	GO:0016458	138	0.017
chromatin remodeling	GO:0006338	72	0.016
nucleotide excision repair	GO:0006289	8	0.016
gland morphogenesis	GO:0022612	145	0.016
negative regulation of signaling	GO:0023057	219	0.016
negative regulation of cellular metabolic process	GO:0031324	382	0.016
small molecule metabolic process	GO:0044281	305	0.016
cell migration	GO:0016477	238	0.016
chromatin modification	GO:0016568	147	0.015
positive regulation of developmental process	GO:0051094	143	0.015
organic substance transport	GO:0071702	257	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
multi organism reproductive behavior	GO:0044705	121	0.014
cellular response to organic substance	GO:0071310	132	0.014
immune response	GO:0006955	246	0.014
negative regulation of cell communication	GO:0010648	223	0.014
border follicle cell delamination	GO:0030709	3	0.014
multi multicellular organism process	GO:0044706	123	0.014
organic acid metabolic process	GO:0006082	103	0.014
response to organic substance	GO:0010033	284	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
regulation of phosphate metabolic process	GO:0019220	210	0.014
carbohydrate derivative metabolic process	GO:1901135	217	0.013
regulation of organelle organization	GO:0033043	196	0.013
defense response to other organism	GO:0098542	225	0.013
organophosphate metabolic process	GO:0019637	195	0.013
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.013
ncrna metabolic process	GO:0034660	43	0.013
chromosome organization	GO:0051276	360	0.013
regulation of cell morphogenesis	GO:0022604	163	0.013
regulation of cellular component size	GO:0032535	98	0.013
innate immune response	GO:0045087	144	0.012
negative regulation of developmental pigmentation	GO:0048086	1	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.012
dendrite morphogenesis	GO:0048813	199	0.012
regulation of cell proliferation	GO:0042127	163	0.012
intermediate filament cytoskeleton organization	GO:0045104	1	0.012
intracellular transport	GO:0046907	228	0.012
intermediate filament based process	GO:0045103	1	0.012
negative regulation of molecular function	GO:0044092	51	0.012
dendrite development	GO:0016358	204	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
regulation of programmed cell death	GO:0043067	152	0.012
formation of a compartment boundary	GO:0060288	4	0.012
regulation of response to external stimulus	GO:0032101	115	0.012
positive regulation of signaling	GO:0023056	243	0.011
positive regulation of neuron projection regeneration	GO:0070572	3	0.011
cellular amine metabolic process	GO:0044106	12	0.011
vesicle mediated transport	GO:0016192	381	0.011
regulation of transport	GO:0051049	181	0.011
regulation of cellular amino acid metabolic process	GO:0006521	0	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.011
response to endogenous stimulus	GO:0009719	119	0.011
amine metabolic process	GO:0009308	12	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
modification dependent macromolecule catabolic process	GO:0043632	79	0.011
proteolysis	GO:0006508	192	0.011
gland development	GO:0048732	191	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
peptidyl serine phosphorylation	GO:0018105	7	0.011
posttranscriptional gene silencing by rna	GO:0035194	45	0.010
embryonic pattern specification	GO:0009880	174	0.010
gene silencing by rna	GO:0031047	57	0.010
camera type eye development	GO:0043010	4	0.010
aromatic compound catabolic process	GO:0019439	166	0.010
body morphogenesis	GO:0010171	2	0.010
positive regulation of epidermal growth factor activated receptor activity	GO:0045741	1	0.010

Art1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.013

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