IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Lcp3 (Dmel_CG2043)

Larval cuticle protein 3

(Aliases: CG2043,DmelLcp3,DMLCP3,L[[3]]CP3,LCP-3,3,Dmel\CG2043,LCP3,CP3,III,LcpIII)

FLYBASE: FBgn0002534
Entrez: 35819
UniProtKB: P07188

Process Predictions
Disease Predictions

Lcp3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
immune response	GO:0006955	246	0.819	Fly
humoral immune response	GO:0006959	117	0.815	Fly
innate immune response	GO:0045087	144	0.734	Fly
response to wounding	GO:0009611	94	0.352	Fly
hemolymph coagulation	GO:0042381	10	0.306	Fly
wound healing	GO:0042060	75	0.286	Fly
regulation of body fluid levels	GO:0050878	14	0.253	Fly
immune system process	GO:0002376	347	0.189	Fly
defense response	GO:0006952	300	0.087	Fly
hemostasis	GO:0007599	10	0.058	Fly
small molecule metabolic process	GO:0044281	305	0.039
response to organic substance	GO:0010033	284	0.039
positive regulation of biosynthetic process	GO:0009891	316	0.039
intracellular protein transmembrane transport	GO:0065002	4	0.037
negative regulation of gene expression	GO:0010629	387	0.036
organonitrogen compound metabolic process	GO:1901564	318	0.031
vesicle mediated transport	GO:0016192	381	0.031
response to sterol	GO:0036314	34	0.029
response to oxygen containing compound	GO:1901700	200	0.028
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.027
cellular protein modification process	GO:0006464	438	0.026
axonogenesis	GO:0007409	290	0.026
organelle fission	GO:0048285	340	0.026
melanization defense response	GO:0035006	45	0.026
compound eye development	GO:0048749	307	0.026
phagocytosis	GO:0006909	215	0.025
coagulation	GO:0050817	10	0.024	Fly
body morphogenesis	GO:0010171	2	0.024
catabolic process	GO:0009056	409	0.023
organic substance catabolic process	GO:1901575	308	0.023
organic substance transport	GO:0071702	257	0.023
positive regulation of signaling	GO:0023056	243	0.023
phosphorylation	GO:0016310	294	0.023
cell death	GO:0008219	279	0.023
regulation of multicellular organismal development	GO:2000026	414	0.022
response to lipopolysaccharide	GO:0032496	4	0.022
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.022
amine metabolic process	GO:0009308	12	0.021
response to abiotic stimulus	GO:0009628	341	0.021
taxis	GO:0042330	304	0.021
positive regulation of rna biosynthetic process	GO:1902680	266	0.021
positive regulation of macromolecule metabolic process	GO:0010604	405	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.020
positive regulation of cell communication	GO:0010647	250	0.020
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.020
cellular amino acid metabolic process	GO:0006520	61	0.020
purine containing compound metabolic process	GO:0072521	155	0.020
pigment metabolic process	GO:0042440	84	0.020
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.020
cellular macromolecule localization	GO:0070727	220	0.020
negative regulation of developmental process	GO:0051093	201	0.020
monocarboxylic acid transport	GO:0015718	3	0.020
transcription from rna polymerase ii promoter	GO:0006366	368	0.020
death	GO:0016265	284	0.020
adult behavior	GO:0030534	137	0.020
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.019
endocytosis	GO:0006897	310	0.019
negative regulation of cellular metabolic process	GO:0031324	382	0.019
programmed cell death	GO:0012501	257	0.019
neuron recognition	GO:0008038	101	0.019
regionalization	GO:0003002	416	0.019
camera type eye development	GO:0043010	4	0.019
actin filament based process	GO:0030029	220	0.019
positive regulation of cellular biosynthetic process	GO:0031328	316	0.019
response to alcohol	GO:0097305	95	0.019
negative regulation of transcription dna templated	GO:0045892	237	0.018
cell recognition	GO:0008037	102	0.018
regulation of cellular amino acid metabolic process	GO:0006521	0	0.018
organophosphate metabolic process	GO:0019637	195	0.018
regulation of localization	GO:0032879	275	0.018
regulation of catalytic activity	GO:0050790	185	0.018
establishment of localization in cell	GO:0051649	402	0.018
response to endogenous stimulus	GO:0009719	119	0.018
telencephalon development	GO:0021537	2	0.018
protein import	GO:0017038	55	0.018
forebrain development	GO:0030900	2	0.018
macromolecular complex assembly	GO:0065003	256	0.018
proteolysis	GO:0006508	192	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018
gene silencing	GO:0016458	138	0.018
positive regulation of signal transduction	GO:0009967	223	0.017
single organism biosynthetic process	GO:0044711	206	0.017
salivary gland morphogenesis	GO:0007435	145	0.017
exocrine system development	GO:0035272	162	0.017
negative regulation of biosynthetic process	GO:0009890	277	0.017
cellular response to chemical stimulus	GO:0070887	199	0.017
negative regulation of response to stimulus	GO:0048585	258	0.017
negative regulation of rna biosynthetic process	GO:1902679	240	0.017
negative regulation of cellular biosynthetic process	GO:0031327	277	0.017
intracellular transport	GO:0046907	228	0.017
cellular catabolic process	GO:0044248	372	0.016
protein localization	GO:0008104	284	0.016
purine ribonucleotide metabolic process	GO:0009150	145	0.016
cellular amine metabolic process	GO:0044106	12	0.016
nuclear division	GO:0000280	332	0.016
nucleobase containing small molecule metabolic process	GO:0055086	174	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
salivary gland development	GO:0007431	162	0.016
cellular response to organic substance	GO:0071310	132	0.016
single organism intracellular transport	GO:1902582	207	0.016
positive regulation of transcription dna templated	GO:0045893	266	0.016
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.016
retina development in camera type eye	GO:0060041	4	0.016
g protein coupled receptor signaling pathway	GO:0007186	136	0.016
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.016
synaptic target recognition	GO:0008039	45	0.016
eye development	GO:0001654	323	0.016
segmentation	GO:0035282	207	0.015
axon development	GO:0061564	297	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
appendage morphogenesis	GO:0035107	397	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.015
post embryonic appendage morphogenesis	GO:0035120	385	0.015
tube development	GO:0035295	244	0.015
intracellular signal transduction	GO:0035556	300	0.015
negative regulation of signal transduction	GO:0009968	206	0.015
imaginal disc derived wing morphogenesis	GO:0007476	337	0.015
regulation of nervous system development	GO:0051960	248	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.015
nucleotide metabolic process	GO:0009117	161	0.015
protein modification process	GO:0036211	438	0.015
cellular response to oxygen containing compound	GO:1901701	79	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
purine nucleotide metabolic process	GO:0006163	146	0.014
nucleoside metabolic process	GO:0009116	127	0.014
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.014
ribose phosphate metabolic process	GO:0019693	145	0.014
regulation of cell morphogenesis	GO:0022604	163	0.014
regulation of transport	GO:0051049	181	0.014
cellular ketone metabolic process	GO:0042180	24	0.014
gland development	GO:0048732	191	0.014
actin filament based movement	GO:0030048	26	0.014
hindbrain development	GO:0030902	2	0.014
positive regulation of response to stimulus	GO:0048584	323	0.014
response to monosaccharide	GO:0034284	4	0.014
homeostatic process	GO:0042592	199	0.014
regulation of gene silencing	GO:0060968	63	0.014
lateral inhibition	GO:0046331	206	0.014
axon guidance	GO:0007411	233	0.014
eye morphogenesis	GO:0048592	260	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
positive regulation of catalytic activity	GO:0043085	118	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.013
respiratory system development	GO:0060541	213	0.013
ribonucleotide metabolic process	GO:0009259	145	0.013
imaginal disc derived appendage development	GO:0048737	399	0.013
cell maturation	GO:0048469	144	0.013
organonitrogen compound biosynthetic process	GO:1901566	117	0.013
activation of innate immune response	GO:0002218	4	0.013
regulation of gene expression epigenetic	GO:0040029	128	0.013
regulation of response to stress	GO:0080134	200	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
protein complex assembly	GO:0006461	200	0.013
apoptotic process	GO:0006915	159	0.013
immune response activating signal transduction	GO:0002757	2	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
chromatin silencing	GO:0006342	76	0.013
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
multicellular organismal aging	GO:0010259	140	0.013
regulation of cell cycle	GO:0051726	291	0.013
regulation of embryonic development	GO:0045995	68	0.013
establishment of protein localization	GO:0045184	163	0.013
organelle assembly	GO:0070925	198	0.013
secretion by cell	GO:0032940	101	0.013
phenol containing compound metabolic process	GO:0018958	57	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
epithelial cell development	GO:0002064	274	0.013
regulation of cellular component biogenesis	GO:0044087	201	0.013
compound eye morphogenesis	GO:0001745	249	0.013
appendage development	GO:0048736	401	0.013
intracellular protein transport	GO:0006886	104	0.013
anatomical structure homeostasis	GO:0060249	97	0.013
wing disc morphogenesis	GO:0007472	344	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
antimicrobial humoral response	GO:0019730	99	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
alpha amino acid metabolic process	GO:1901605	20	0.013
regulation of protein metabolic process	GO:0051246	256	0.012
single organism catabolic process	GO:0044712	228	0.012
developmental growth	GO:0048589	280	0.012
cellular protein localization	GO:0034613	160	0.012
positive regulation of molecular function	GO:0044093	136	0.012
regulation of cellular component size	GO:0032535	98	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
synapse assembly	GO:0007416	143	0.012
determination of adult lifespan	GO:0008340	137	0.012
gland morphogenesis	GO:0022612	145	0.012
regulation of molecular function	GO:0065009	217	0.012
mapk cascade	GO:0000165	107	0.012
dendrite morphogenesis	GO:0048813	199	0.012
regulation of multi organism process	GO:0043900	131	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
positive regulation of gene expression	GO:0010628	290	0.012
cellular response to lipopolysaccharide	GO:0071222	3	0.012
response to external biotic stimulus	GO:0043207	293	0.012
mitotic nuclear division	GO:0007067	213	0.012
long term memory	GO:0007616	62	0.012
single organism behavior	GO:0044708	391	0.012
regulation of programmed cell death	GO:0043067	152	0.012
photoreceptor cell differentiation	GO:0046530	170	0.012
negative regulation of gene expression epigenetic	GO:0045814	77	0.012
regulation of anatomical structure size	GO:0090066	163	0.012
immune response regulating signaling pathway	GO:0002764	2	0.012
protein transport	GO:0015031	155	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.012
developmental programmed cell death	GO:0010623	138	0.012
neutral lipid catabolic process	GO:0046461	3	0.012
lipid localization	GO:0010876	54	0.012
response to biotic stimulus	GO:0009607	294	0.012
aging	GO:0007568	143	0.011
digestive tract morphogenesis	GO:0048546	127	0.011
neuron projection guidance	GO:0097485	241	0.011
epithelial cell differentiation	GO:0030855	322	0.011
sterol homeostasis	GO:0055092	4	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
blastoderm segmentation	GO:0007350	159	0.011
oxoacid metabolic process	GO:0043436	103	0.011
positive regulation of multi organism process	GO:0043902	40	0.011
gastrulation	GO:0007369	70	0.011
maintenance of location	GO:0051235	73	0.011
organophosphate catabolic process	GO:0046434	112	0.011
regulation of apoptotic process	GO:0042981	130	0.011
melanin metabolic process	GO:0006582	47	0.011
developmental maturation	GO:0021700	172	0.011
negative regulation of nervous system development	GO:0051961	92	0.011
regulation of phosphorylation	GO:0042325	147	0.011
carboxylic acid metabolic process	GO:0019752	92	0.011
synapse organization	GO:0050808	196	0.011
defense response to other organism	GO:0098542	225	0.011
cell migration	GO:0016477	238	0.011
negative regulation of signaling	GO:0023057	219	0.010
regulation of cellular localization	GO:0060341	136	0.010
posttranscriptional regulation of gene expression	GO:0010608	145	0.010
secondary metabolic process	GO:0019748	75	0.010
protein phosphorylation	GO:0006468	169	0.010
macromolecule catabolic process	GO:0009057	161	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
defense response to bacterium	GO:0042742	178	0.010
regulation of cell death	GO:0010941	173	0.010
negative regulation of cell communication	GO:0010648	223	0.010
purine ribonucleoside metabolic process	GO:0046128	127	0.010
regulation of developmental growth	GO:0048638	174	0.010
organic acid metabolic process	GO:0006082	103	0.010
synaptic transmission	GO:0007268	288	0.010
negative regulation of multicellular organismal process	GO:0051241	142	0.010
regulation of purine nucleotide metabolic process	GO:1900542	62	0.010
chemosensory behavior	GO:0007635	106	0.010
positive regulation of hydrolase activity	GO:0051345	78	0.010
wnt signaling pathway	GO:0016055	98	0.010
nucleobase containing compound catabolic process	GO:0034655	165	0.010
response to decreased oxygen levels	GO:0036293	58	0.010
response to ecdysone	GO:0035075	34	0.010

Lcp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.027
disease of metabolism	DOID:0014667	0.021
nervous system disease	DOID:863	0.019
acquired metabolic disease	DOID:0060158	0.012
hypophosphatasia	DOID:14213	0.010
inherited metabolic disorder	DOID:655	0.010

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