IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG17646 (Dmel_CG17646)

CG17646 gene product from transcript CG17646-RB

(Aliases: CG17647,Dmel\CG17646,BEST:GH05015)

Entrez: 33354
FLYBASE: FBgn0031362
UniProtKB: Q8T9E6

Process Predictions
Disease Predictions

CG17646 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
imaginal disc derived appendage development	GO:0048737	399	0.144
l amino acid import	GO:0043092	2	0.140
regionalization	GO:0003002	416	0.120
wing disc morphogenesis	GO:0007472	344	0.115
endocytosis	GO:0006897	310	0.113	Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.089
vesicle mediated transport	GO:0016192	381	0.074	Fly
imaginal disc derived wing morphogenesis	GO:0007476	337	0.071
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.067
sodium dependent phosphate transport	GO:0044341	2	0.062
phagocytosis	GO:0006909	215	0.058	Fly
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.049
appendage morphogenesis	GO:0035107	397	0.047
columnar cuboidal epithelial cell development	GO:0002066	249	0.047
imaginal disc derived wing vein specification	GO:0007474	48	0.044
appendage development	GO:0048736	401	0.044
epithelial cell development	GO:0002064	274	0.040
eggshell formation	GO:0030703	105	0.036
chorion containing eggshell formation	GO:0007304	105	0.036
regulation of cellular ketone metabolic process	GO:0010565	3	0.035
dorsal ventral pattern formation	GO:0009953	133	0.034
organic substance transport	GO:0071702	257	0.033
epithelial cell differentiation	GO:0030855	322	0.033
phosphate ion transport	GO:0006817	4	0.032
small molecule metabolic process	GO:0044281	305	0.031
cell death	GO:0008219	279	0.031
imaginal disc pattern formation	GO:0007447	91	0.030
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.030
regulation of multi organism process	GO:0043900	131	0.030
hormone catabolic process	GO:0042447	3	0.030
carboxylic acid metabolic process	GO:0019752	92	0.029
single organism biosynthetic process	GO:0044711	206	0.029
catabolic process	GO:0009056	409	0.028
ion transport	GO:0006811	145	0.027
defense response to other organism	GO:0098542	225	0.026
body morphogenesis	GO:0010171	2	0.025
neutral lipid biosynthetic process	GO:0046460	2	0.025
response to other organism	GO:0051707	293	0.025
response to external biotic stimulus	GO:0043207	293	0.024
organic acid metabolic process	GO:0006082	103	0.024
acylglycerol biosynthetic process	GO:0046463	2	0.024
cellular component assembly involved in morphogenesis	GO:0010927	151	0.023
male meiosis	GO:0007140	52	0.023
phosphorylation	GO:0016310	294	0.023
organelle assembly	GO:0070925	198	0.023
l glutamate import	GO:0051938	1	0.022
eggshell chorion assembly	GO:0007306	66	0.022
biological adhesion	GO:0022610	138	0.022
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021
embryonic morphogenesis	GO:0048598	206	0.021
negative regulation of signaling	GO:0023057	219	0.021
cellular ketone metabolic process	GO:0042180	24	0.021
taxis	GO:0042330	304	0.021
mating	GO:0007618	120	0.020
chemotaxis	GO:0006935	249	0.020
acylglycerol metabolic process	GO:0006639	12	0.020
multi organism reproductive behavior	GO:0044705	121	0.020
death	GO:0016265	284	0.020
negative regulation of signal transduction	GO:0009968	206	0.019
multi organism behavior	GO:0051705	175	0.018
dorsal appendage formation	GO:0046843	47	0.018
compound eye development	GO:0048749	307	0.018
single organism behavior	GO:0044708	391	0.018	Fly
lipid metabolic process	GO:0006629	121	0.018
cellular protein modification process	GO:0006464	438	0.018
positive regulation of macromolecule metabolic process	GO:0010604	405	0.018
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.018
androgen metabolic process	GO:0008209	1	0.018
positive regulation of cell communication	GO:0010647	250	0.018
organonitrogen compound biosynthetic process	GO:1901566	117	0.018
microtubule organizing center organization	GO:0031023	168	0.017
cell division	GO:0051301	248	0.017
negative regulation of cell communication	GO:0010648	223	0.017
cellular amino acid metabolic process	GO:0006520	61	0.017
ovarian follicle cell development	GO:0030707	248	0.017
ribonucleotide metabolic process	GO:0009259	145	0.017
wing disc pattern formation	GO:0035222	66	0.017
response to biotic stimulus	GO:0009607	294	0.017
carotenoid metabolic process	GO:0016116	1	0.017
gland development	GO:0048732	191	0.017
response to lipopolysaccharide	GO:0032496	4	0.017
oligosaccharide transport	GO:0015772	2	0.017
regulation of nervous system development	GO:0051960	248	0.017
actin cytoskeleton organization	GO:0030036	206	0.017
response to bacterium	GO:0009617	198	0.016
protein modification process	GO:0036211	438	0.016
response to abiotic stimulus	GO:0009628	341	0.016
compound eye morphogenesis	GO:0001745	249	0.016
establishment of localization in cell	GO:0051649	402	0.016
anion transport	GO:0006820	41	0.015
developmental programmed cell death	GO:0010623	138	0.015
single organism intracellular transport	GO:1902582	207	0.015
oxoacid metabolic process	GO:0043436	103	0.015
histolysis	GO:0007559	102	0.015
tube development	GO:0035295	244	0.015
regulation of protein metabolic process	GO:0051246	256	0.015
tube morphogenesis	GO:0035239	191	0.015
lateral inhibition	GO:0046331	206	0.015
positive regulation of cell motility	GO:2000147	3	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
organonitrogen compound metabolic process	GO:1901564	318	0.015
organic substance catabolic process	GO:1901575	308	0.015
neuroblast proliferation	GO:0007405	74	0.015
carbohydrate derivative metabolic process	GO:1901135	217	0.015
positive regulation of cell migration	GO:0030335	2	0.015
kidney development	GO:0001822	3	0.015
meiosis i	GO:0007127	59	0.014
regulation of cell development	GO:0060284	215	0.014
salivary gland morphogenesis	GO:0007435	145	0.014
positive regulation of response to stimulus	GO:0048584	323	0.014
defense response	GO:0006952	300	0.014
cellular catabolic process	GO:0044248	372	0.014
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.014
cellular lipid metabolic process	GO:0044255	83	0.014
response to organic substance	GO:0010033	284	0.014
centrosome organization	GO:0051297	163	0.014
synapse organization	GO:0050808	196	0.013
cell growth	GO:0016049	108	0.013
defense response to bacterium	GO:0042742	178	0.013
posttranscriptional regulation of gene expression	GO:0010608	145	0.013
regulation of multicellular organismal development	GO:2000026	414	0.013
glutamine metabolic process	GO:0006541	4	0.013
negative regulation of cell differentiation	GO:0045596	143	0.013
regulation of catabolic process	GO:0009894	170	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013
synapse assembly	GO:0007416	143	0.013
transmembrane transport	GO:0055085	139	0.013
cell fate determination	GO:0001709	91	0.012
centrosome cycle	GO:0007098	137	0.012
eye morphogenesis	GO:0048592	260	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.012
notch signaling pathway	GO:0007219	120	0.012
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.012
eye development	GO:0001654	323	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
telencephalon development	GO:0021537	2	0.012
connective tissue development	GO:0061448	3	0.012
meiotic cell cycle process	GO:1903046	132	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
ras protein signal transduction	GO:0007265	88	0.012
nuclear division	GO:0000280	332	0.012
forebrain development	GO:0030900	2	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
phagocytosis recognition	GO:0006910	1	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
thioester metabolic process	GO:0035383	3	0.012
wing disc dorsal ventral pattern formation	GO:0048190	47	0.012
positive regulation of signal transduction	GO:0009967	223	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
segmentation	GO:0035282	207	0.012
digestive system development	GO:0055123	149	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
cell motility	GO:0048870	251	0.011
regulation of developmental growth	GO:0048638	174	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
nucleobase containing small molecule metabolic process	GO:0055086	174	0.011
imaginal disc derived leg morphogenesis	GO:0007480	80	0.011
neurological system process	GO:0050877	358	0.011
immune system process	GO:0002376	347	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
epithelium migration	GO:0090132	148	0.011
detection of external stimulus	GO:0009581	66	0.011
homeostatic process	GO:0042592	199	0.011
purine ribonucleotide biosynthetic process	GO:0009152	28	0.011
response to oxygen containing compound	GO:1901700	200	0.011
single organism carbohydrate metabolic process	GO:0044723	72	0.011
respiratory system development	GO:0060541	213	0.011
centrosome duplication	GO:0051298	121	0.011
regulation of organelle organization	GO:0033043	196	0.011
regulation of catalytic activity	GO:0050790	185	0.011
gastrulation	GO:0007369	70	0.011
neutral lipid metabolic process	GO:0006638	12	0.011
digestive tract morphogenesis	GO:0048546	127	0.011
determination of adult lifespan	GO:0008340	137	0.011
positive regulation of signaling	GO:0023056	243	0.011
positive regulation of lipid storage	GO:0010884	4	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
digestive tract development	GO:0048565	149	0.010
programmed cell death	GO:0012501	257	0.010
secretion	GO:0046903	109	0.010
actin filament based process	GO:0030029	220	0.010
cellular response to dna damage stimulus	GO:0006974	223	0.010
carbohydrate derivative biosynthetic process	GO:1901137	85	0.010
regulation of cell cycle	GO:0051726	291	0.010
salivary gland cell autophagic cell death	GO:0035071	83	0.010
phototransduction	GO:0007602	52	0.010
regulation of lipid transport	GO:0032368	3	0.010
tissue death	GO:0016271	102	0.010
organophosphate metabolic process	GO:0019637	195	0.010
actin filament organization	GO:0007015	126	0.010
nitrogen compound transport	GO:0071705	85	0.010
regulation of response to stress	GO:0080134	200	0.010
multi multicellular organism process	GO:0044706	123	0.010

CG17646 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.013
disease of metabolism	DOID:0014667	0.013
disease of anatomical entity	DOID:7	0.012
musculoskeletal system disease	DOID:17	0.012
nervous system disease	DOID:863	0.012
connective tissue disease	DOID:65	0.011

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