Drosophila melanogaster

96 known processes

Tip60 (Dmel_CG6121)

CG6121 gene product from transcript CG6121-RA

(Aliases: CG6121,EG:EG0007.7,dmHAG405,Dmel\TIP60,Dmel\CG6121,dTip60,Dmel/TIP60,6121,EG0007.7,dTIP60,DmEG0007.7)

Tip60 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular metabolic processGO:00313243820.947
negative regulation of cellular biosynthetic processGO:00313272770.895
negative regulation of transcription dna templatedGO:00458922370.833
negative regulation of nucleic acid templated transcriptionGO:19035072400.717
negative regulation of nitrogen compound metabolic processGO:00511722650.713
positive regulation of developmental growthGO:0048639620.663
cytoskeleton dependent cytokinesisGO:0061640810.642
negative regulation of rna biosynthetic processGO:19026792400.519
cytokinesisGO:0000910900.515
negative regulation of rna metabolic processGO:00512532510.444
dna integrity checkpointGO:0031570810.441
Fly
mitotic cell cycle checkpointGO:0007093880.439
negative regulation of response to stimulusGO:00485852580.437
regulation of developmental growthGO:00486381740.430
transcription from rna polymerase ii promoterGO:00063663680.382
Mouse Rat
growthGO:00400073590.364
negative regulation of cellular component organizationGO:00511291080.360
developmental growthGO:00485892800.351
regulation of cell cycleGO:00517262910.347
protein modification processGO:00362114380.340
protein localization to organelleGO:0033365820.338
Worm
negative regulation of gene expressionGO:00106293870.336
proteolysis involved in cellular protein catabolic processGO:0051603830.329
cellular macromolecule catabolic processGO:00442651360.308
regulation of cell cycle processGO:00105641810.306
meiotic cytokinesisGO:0033206330.304
positive regulation of developmental processGO:00510941430.300
cellular protein localizationGO:00346131600.296
Worm
mitotic g2 m transition checkpointGO:0044818700.292
positive regulation of cell communicationGO:00106472500.281
regulation of mitotic cell cycleGO:00073461900.279
cell deathGO:00082192790.276
regulation of anatomical structure morphogenesisGO:00226032420.276
cellular protein modification processGO:00064644380.275
multi organism behaviorGO:00517051750.274
catabolic processGO:00090564090.274
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.269
dendrite developmentGO:00163582040.264
negative regulation of nucleobase containing compound metabolic processGO:00459342610.261
positive regulation of multicellular organism growthGO:0040018210.258
modification dependent protein catabolic processGO:0019941780.257
meiotic nuclear divisionGO:00071261510.251
mitotic cell cycle phase transitionGO:00447721380.250
positive regulation of response to stimulusGO:00485843230.234
establishment or maintenance of cell polarityGO:00071631670.230
meiotic cell cycleGO:00513211710.230
organelle fissionGO:00482853400.218
organic substance catabolic processGO:19015753080.210
modification dependent macromolecule catabolic processGO:0043632790.208
negative regulation of macromolecule biosynthetic processGO:00105582700.203
regulation of transcription from rna polymerase ii promoterGO:00063573780.200
Mouse Rat
g2 dna damage checkpointGO:0031572690.194
positive regulation of multicellular organismal processGO:00512401430.192
dna damage checkpointGO:0000077780.188
Fly
positive regulation of rna biosynthetic processGO:19026802660.187
Mouse Rat
mitotic g2 dna damage checkpointGO:0007095690.183
negative regulation of protein tyrosine kinase activityGO:006109950.181
protein localizationGO:00081042840.180
Worm
regionalizationGO:00030024160.177
negative regulation of cell cycle processGO:00109481090.175
positive regulation of transcription dna templatedGO:00458932660.170
Mouse Rat
regulation of localizationGO:00328792750.166
positive regulation of nucleic acid templated transcriptionGO:19035082660.164
Mouse Rat
proteolysisGO:00065081920.162
regulation of mitotic cell cycle phase transitionGO:19019901300.158
organelle assemblyGO:00709251980.158
cellular catabolic processGO:00442483720.156
embryo development ending in birth or egg hatchingGO:00097921520.156
Worm
regulation of cell cycle phase transitionGO:19019871300.146
negative regulation of cell cycleGO:00457861160.145
proteasomal protein catabolic processGO:0010498590.140
axis specificationGO:00097981670.134
chromosome organizationGO:00512763600.131
positive regulation of nitrogen compound metabolic processGO:00511733540.131
Mouse Rat
histone modificationGO:00165701060.129
nuclear divisionGO:00002803320.126
regulation of erbb signaling pathwayGO:1901184420.122
positive regulation of growthGO:0045927750.122
organic substance transportGO:00717022570.122
regulation of multicellular organismal developmentGO:20000264140.119
Worm
mitotic cytokinesisGO:0000281500.117
cellular protein catabolic processGO:0044257830.116
phosphorylationGO:00163102940.114
response to organic substanceGO:00100332840.114
cell cycle phase transitionGO:00447701400.113
multi organism reproductive behaviorGO:00447051210.111
negative regulation of nervous system developmentGO:0051961920.107
peptidyl amino acid modificationGO:00181931050.106
negative regulation of signalingGO:00230572190.103
positive regulation of cellular biosynthetic processGO:00313283160.101
Mouse Rat
mitotic dna integrity checkpointGO:0044774750.097
macromolecular complex assemblyGO:00650032560.095
macromolecule catabolic processGO:00090571610.093
negative regulation of mitotic cell cycle phase transitionGO:19019911030.093
regulation of protein deacetylationGO:009031120.093
regulation of programmed cell deathGO:00430671520.087
single organism behaviorGO:00447083910.087
ubiquitin dependent protein catabolic processGO:0006511780.085
multicellular organismal agingGO:00102591400.085
cellular macromolecule localizationGO:00707272200.084
Worm
synapse assemblyGO:00074161430.083
positive regulation of signalingGO:00230562430.081
protein importGO:0017038550.079
programmed cell deathGO:00125012570.079
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.077
regulation of cell differentiationGO:00455953020.076
protein acetylationGO:0006473390.076
developmental maturationGO:00217001720.075
female meiotic divisionGO:0007143700.075
regulation of cell shapeGO:00083601130.073
macromolecule deacylationGO:0098732110.072
notch signaling pathwayGO:00072191200.072
negative regulation of cell cycle phase transitionGO:19019881030.071
protein phosphorylationGO:00064681690.070
appendage morphogenesisGO:00351073970.067
positive regulation of signal transductionGO:00099672230.066
organic acid metabolic processGO:00060821030.066
cytokinetic processGO:0032506270.064
regulation of cellular component biogenesisGO:00440872010.062
protein catabolic processGO:00301631010.061
male meiosis cytokinesisGO:0007112260.061
cell maturationGO:00484691440.061
positive regulation of cellular component organizationGO:00511301560.061
negative regulation of cell communicationGO:00106482230.061
positive regulation of nervous system developmentGO:0051962690.059
protein localization to nucleusGO:0034504550.059
intracellular transportGO:00469072280.059
positive regulation of nucleocytoplasmic transportGO:0046824240.058
regulation of cell developmentGO:00602842150.056
larval developmentGO:00021641040.055
Worm
body morphogenesisGO:001017120.055
Worm
oxoacid metabolic processGO:00434361030.055
carboxylic acid metabolic processGO:0019752920.054
cell divisionGO:00513012480.053
morphogenesis of a branching epitheliumGO:0061138450.051
histone h4 k16 acetylationGO:004398440.051
Fly
mitotic nuclear divisionGO:00070672130.051
regulation of cellular protein metabolic processGO:00322682430.050
Fly
segmentationGO:00352822070.049
regulation of growthGO:00400082330.048
negative regulation of protein metabolic processGO:0051248850.046
negative regulation of signal transductionGO:00099682060.046
gene silencingGO:00164581380.045
establishment of localization in cellGO:00516494020.045
negative regulation of gene expression epigeneticGO:0045814770.045
chromatin silencingGO:0006342760.045
protein localization to peroxisomeGO:007266220.045
negative regulation of phosphorus metabolic processGO:0010563450.044
compound eye developmentGO:00487493070.043
regulation of phosphorylationGO:00423251470.043
negative regulation of biosynthetic processGO:00098902770.042
negative regulation of multicellular organismal processGO:00512411420.042
Worm
positive regulation of transportGO:0051050920.042
positive regulation of rna metabolic processGO:00512542710.041
Mouse Rat
multicellular organismal reproductive behaviorGO:00330571100.041
reproductive structure developmentGO:0048608740.041
regulation of response to stressGO:00801342000.040
Fly
protein acylationGO:0043543420.040
histone h3 k9 acetylationGO:004397030.039
maintenance of protein locationGO:0045185280.038
regulation of response to external stimulusGO:00321011150.038
maintenance of location in cellGO:0051651280.038
protein targetingGO:0006605640.037
cognitionGO:00508901410.037
embryonic axis specificationGO:00005781070.036
mitotic dna damage checkpointGO:0044773740.036
determination of adult lifespanGO:00083401370.036
cellular macromolecular complex assemblyGO:00346221530.035
lipid metabolic processGO:00066291210.035
protein complex biogenesisGO:00702712010.035
protein complex assemblyGO:00064612000.034
regulation of wnt signaling pathwayGO:0030111680.034
cellular response to chemical stimulusGO:00708871990.034
Rat
reproductive system developmentGO:0061458740.034
synapse organizationGO:00508081960.033
appendage developmentGO:00487364010.033
regulation of synapse organizationGO:00508071100.033
microtubule based movementGO:0007018510.033
positive regulation of autophagyGO:0010508210.033
negative regulation of mitotic cell cycleGO:00459301090.032
negative regulation of receptor activityGO:200027230.031
reproductive behaviorGO:00190981220.031
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.030
Mouse Rat
muscle structure developmentGO:00610612240.030
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.030
intracellular signal transductionGO:00355563000.030
Fly
autophagyGO:00069141080.030
larval midgut cell programmed cell deathGO:0035096190.029
regulation of phosphate metabolic processGO:00192202100.029
imaginal disc derived wing morphogenesisGO:00074763370.028
nucleotide excision repairGO:000628980.028
regulation of cell morphogenesisGO:00226041630.028
phagocytosisGO:00069092150.028
regulation of cellular amino acid metabolic processGO:000652100.028
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.028
cell cycle checkpointGO:0000075950.028
Fly
deathGO:00162652840.027
protein ubiquitinationGO:0016567700.027
embryonic pattern specificationGO:00098801740.027
peptidyl lysine acetylationGO:0018394390.027
regulation of dendrite developmentGO:0050773370.027
single organism cellular localizationGO:19025801800.027
protein transportGO:00150311550.026
positive regulation of biosynthetic processGO:00098913160.026
Mouse Rat
response to nutrient levelsGO:00316671140.026
negative regulation of apoptotic processGO:0043066630.025
meiotic cell cycle processGO:19030461320.025
cellular response to starvationGO:0009267610.025
negative regulation of molecular functionGO:0044092510.025
imaginal disc derived appendage developmentGO:00487373990.024
anatomical structure homeostasisGO:0060249970.024
neuroblast proliferationGO:0007405740.024
cytoplasmic transportGO:00164821300.024
negative regulation of neurogenesisGO:0050768530.023
negative regulation of developmental processGO:00510932010.023
Worm
regulation of cellular protein catabolic processGO:1903362440.023
regulation of synapse structure and activityGO:00508031280.023
negative regulation of organelle organizationGO:0010639560.023
gliogenesisGO:0042063800.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.023
negative regulation of erbb signaling pathwayGO:1901185290.022
single organism intracellular transportGO:19025822070.022
macroautophagyGO:0016236420.022
response to organic cyclic compoundGO:0014070890.022
regulation of proteolysisGO:0030162870.022
compound eye morphogenesisGO:00017452490.022
skeletal muscle fiber developmentGO:004874130.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
Mouse Rat
regulation of neuron projection developmentGO:0010975690.021
ovipositionGO:0018991190.021
protein processingGO:0016485680.021
apoptotic signaling pathwayGO:0097190270.021
positive regulation of protein deacetylationGO:009031220.021
response to external biotic stimulusGO:00432072930.020
cell proliferationGO:00082832990.020
blastoderm segmentationGO:00073501590.020
multicellular organism growthGO:0035264460.020
regulation of chromosome organizationGO:0033044640.020
Fly
male gamete generationGO:00482322010.020
development of primary sexual characteristicsGO:0045137500.020
regulation of cellular response to stressGO:0080135890.019
Fly
covalent chromatin modificationGO:00165691060.019
dendrite morphogenesisGO:00488131990.019
negative regulation of cellular protein metabolic processGO:0032269850.019
regulation of neurogenesisGO:00507671580.019
negative regulation of phosphate metabolic processGO:0045936450.019
regulation of molecular functionGO:00650092170.019
Fly
response to extracellular stimulusGO:00099911160.019
spindle organizationGO:00070512530.019
photoreceptor cell developmentGO:0042461960.018
oocyte constructionGO:00073081120.018
establishment of protein localizationGO:00451841630.018
regulation of catalytic activityGO:00507901850.018
cellular response to dna damage stimulusGO:00069742230.018
protein maturationGO:0051604710.017
protein modification by small protein conjugationGO:0032446790.017
chromatin organizationGO:00063252070.017
regulation of phosphatase activityGO:001092130.017
autophagic vacuole assemblyGO:000004520.017
nuclear importGO:0051170510.017
single organism catabolic processGO:00447122280.017
regulation of protein metabolic processGO:00512462560.017
Fly
regulation of chromosome segregationGO:0051983320.017
positive regulation of phosphate metabolic processGO:00459371390.017
endocytosisGO:00068973100.017
Worm
regulation of nervous system developmentGO:00519602480.017
regulation of cellular catabolic processGO:00313291570.017
establishment of protein localization to organelleGO:0072594620.017
somatic stem cell divisionGO:0048103370.017
response to other organismGO:00517072930.016
regulation of notch signaling pathwayGO:00085931000.016
regulation of protein localization to nucleusGO:1900180290.016
anterior posterior axis specification embryoGO:00085951030.016
histone h4 acetylationGO:0043967130.016
development of primary male sexual characteristicsGO:004654690.016
multi multicellular organism processGO:00447061230.016
epithelial tube morphogenesisGO:0060562880.016
imaginal disc derived appendage morphogenesisGO:00351143950.016
establishment or maintenance of cytoskeleton polarityGO:0030952440.015
amine metabolic processGO:0009308120.015
regulation of gene expression epigeneticGO:00400291280.015
Fly
oocyte axis specificationGO:00073091080.015
positive regulation of response to extracellular stimulusGO:003210680.015
regulation of protein catabolic processGO:0042176550.015
regulation of cell deathGO:00109411730.015
positive regulation of gene expressionGO:00106282900.015
Mouse Rat
neuron projection guidanceGO:00974852410.015
epidermal growth factor receptor signaling pathwayGO:0007173580.015
synaptic growth at neuromuscular junctionGO:00511241190.015
cell motilityGO:00488702510.015
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.015
erbb signaling pathwayGO:0038127580.015
signal transduction in response to dna damageGO:004277030.015
Fly
mapk cascadeGO:00001651070.015
homeostatic processGO:00425921990.014
protein targeting to nucleusGO:0044744510.014
regulation of mitosisGO:0007088560.014
vesicle mediated transportGO:00161923810.014
Worm
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.014
mrna splice site selectionGO:000637610.014
regulation of phosphorus metabolic processGO:00511742100.014
cell agingGO:000756920.014
regulation of g2 m transition of mitotic cell cycleGO:0010389150.014
golgi organizationGO:0007030660.014
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.014
negative regulation of protein processingGO:0010955310.013
regulation of transportGO:00510491810.013
negative regulation of g2 m transition of mitotic cell cycleGO:001097280.013
chromatin modificationGO:00165681470.013
nucleocytoplasmic transportGO:0006913720.013
negative regulation of ras protein signal transductionGO:0046580130.013
regulation of mapk cascadeGO:0043408920.013
morphogenesis of a branching structureGO:0001763450.013
muscle organ developmentGO:00075171270.013
negative regulation of phosphorylationGO:0042326350.012
regulation of autophagyGO:0010506620.012
protein polyubiquitinationGO:0000209110.012
response to light stimulusGO:00094161240.012
negative regulation of programmed cell deathGO:0043069720.012
protein import into nucleusGO:0006606510.012
regulation of protein processingGO:0070613320.012
post embryonic appendage morphogenesisGO:00351203850.012
regulation of hydrolase activityGO:0051336970.012
regulation of catabolic processGO:00098941700.012
imaginal disc derived leg morphogenesisGO:0007480800.012
actin cytoskeleton organizationGO:00300362060.012
neurological system processGO:00508773580.012
cellular component assembly involved in morphogenesisGO:00109271510.012
regulation of synaptic growth at neuromuscular junctionGO:0008582890.012
pigment cell differentiationGO:005093130.012
cellularizationGO:0007349900.012
establishment of organelle localizationGO:00516561220.011
tube morphogenesisGO:00352391910.011
regulation of epidermal growth factor activated receptor activityGO:000717640.011
regulation of immune responseGO:00507761180.011
developmental pigmentationGO:0048066680.011
oocyte differentiationGO:00099941450.011
regulation of dna metabolic processGO:0051052340.011
regulation of protein tyrosine kinase activityGO:006109790.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.011
regulation of locomotionGO:0040012420.011
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.011
g2 m transition of mitotic cell cycleGO:0000086190.011
nuclear transportGO:0051169720.011
cellular response to external stimulusGO:0071496660.011
myotube cell developmentGO:001490430.011
dna templated transcription initiationGO:0006352250.011
tripartite regional subdivisionGO:00073511030.011
positive regulation of protein metabolic processGO:00512471280.011
positive regulation of phosphorylationGO:0042327870.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
molting cycleGO:0042303560.011
response to woundingGO:0009611940.011
regulation of cellular amine metabolic processGO:003323830.011
eye photoreceptor cell differentiationGO:00017541450.011
stem cell proliferationGO:0072089880.011
histone h4 k12 acetylationGO:004398320.010
regulation of cytokinesisGO:003246530.010
positive regulation of catabolic processGO:00098961050.010
positive regulation of cell cycle processGO:0090068280.010
negative regulation of cell deathGO:0060548810.010
sex differentiationGO:0007548810.010
regulation of cell projection organizationGO:0031344920.010

Tip60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.028
disease of anatomical entityDOID:700.028
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.022
organ system cancerDOID:005068600.022