Drosophila melanogaster

135 known processes

lds (Dmel_CG2684)

lodestar

(Aliases: early,Fs(3)Sz11,lod,NTef2,Fs(3)Hor,Fs(3)Horka,Horka,Lds,CG2684,DmF2,Dmel\CG2684)

lds biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single fertilizationGO:0007338240.972
fertilizationGO:0009566260.865
organelle assemblyGO:00709251980.863
cell divisionGO:00513012480.782
nuclear divisionGO:00002803320.760
regulation of cell cycle phase transitionGO:19019871300.697
microtubule organizing center organizationGO:00310231680.688
organelle fusionGO:0048284460.630
regulation of cell cycleGO:00517262910.600
centrosome organizationGO:00512971630.522
nucleus organizationGO:0006997450.484
spindle organizationGO:00070512530.482
regulation of mitotic cell cycleGO:00073461900.451
macromolecular complex assemblyGO:00650032560.450
meiotic cell cycleGO:00513211710.380
reciprocal meiotic recombinationGO:0007131190.335
single organism cellular localizationGO:19025801800.325
cellular macromolecule localizationGO:00707272200.322
mitotic g2 m transition checkpointGO:0044818700.286
meiotic chromosome segregationGO:0045132590.283
regulation of cell cycle processGO:00105641810.271
negative regulation of cellular metabolic processGO:00313243820.249
Yeast
establishment of localization in cellGO:00516494020.234
negative regulation of mitotic cell cycle phase transitionGO:19019911030.211
cytoplasmic transportGO:00164821300.208
regulation of cellular protein metabolic processGO:00322682430.206
organelle fissionGO:00482853400.204
centrosome duplicationGO:00512981210.202
response to abiotic stimulusGO:00096283410.198
single organism membrane organizationGO:0044802930.189
negative regulation of mitotic cell cycleGO:00459301090.189
negative regulation of cell cycleGO:00457861160.189
regulation of catabolic processGO:00098941700.188
spindle assemblyGO:0051225800.179
localization of cellGO:00516742570.179
spindle assembly involved in mitosisGO:0090307500.178
negative regulation of nitrogen compound metabolic processGO:00511722650.174
Yeast
chromosome separationGO:0051304420.166
positive regulation of macromolecule metabolic processGO:00106044050.164
mitotic spindle organizationGO:00070522200.146
negative regulation of nucleobase containing compound metabolic processGO:00459342610.141
Yeast
regulation of mitotic cell cycle phase transitionGO:19019901300.141
single organism catabolic processGO:00447122280.139
mitotic nuclear divisionGO:00070672130.137
protein complex assemblyGO:00064612000.137
negative regulation of cell cycle processGO:00109481090.136
positive regulation of nucleobase containing compound metabolic processGO:00459353320.135
cell proliferationGO:00082832990.128
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.125
organic substance transportGO:00717022570.124
mitotic dna integrity checkpointGO:0044774750.124
negative regulation of cellular biosynthetic processGO:00313272770.119
regulation of localizationGO:00328792750.118
positive regulation of cellular protein metabolic processGO:00322701180.118
embryo development ending in birth or egg hatchingGO:00097921520.115
regulation of cell divisionGO:0051302720.114
regulation of embryonic pattern specificationGO:1902875270.112
microtubule cytoskeleton organization involved in mitosisGO:1902850520.111
pronuclear fusionGO:000734440.109
cell cycle phase transitionGO:00447701400.108
regulation of multicellular organismal developmentGO:20000264140.107
regulation of gene expression epigeneticGO:00400291280.105
organic substance catabolic processGO:19015753080.103
proteolysisGO:00065081920.102
mitotic cell cycle phase transitionGO:00447721380.101
regulation of protein metabolic processGO:00512462560.097
male meiosisGO:0007140520.094
reciprocal dna recombinationGO:0035825190.093
male gamete generationGO:00482322010.093
cellular catabolic processGO:00442483720.090
rna localizationGO:00064031150.090
meiotic cell cycle processGO:19030461320.089
meiotic spindle organizationGO:0000212360.089
regulation of cell differentiationGO:00455953020.089
regulation of proteasomal protein catabolic processGO:0061136390.089
membrane organizationGO:00610241120.089
chromatin remodelingGO:0006338720.089
centrosome cycleGO:00070981370.087
sister chromatid segregationGO:0000819920.085
retina development in camera type eyeGO:006004140.083
negative regulation of macromolecule biosynthetic processGO:00105582700.082
regulation of proteolysisGO:0030162870.081
negative regulation of biosynthetic processGO:00098902770.080
negative regulation of rna biosynthetic processGO:19026792400.079
spindle assembly involved in meiosisGO:0090306200.079
protein localizationGO:00081042840.078
dna metabolic processGO:00062592270.077
Yeast
cytokinesisGO:0000910900.071
endocytosisGO:00068973100.071
mrna processingGO:00063971040.069
Fly
regulation of mitosisGO:0007088560.068
chromosome segregationGO:00070591570.068
mitotic g2 dna damage checkpointGO:0007095690.068
negative regulation of cell cycle phase transitionGO:19019881030.068
cellular protein modification processGO:00064644380.066
negative regulation of rna metabolic processGO:00512532510.064
cellular macromolecular complex assemblyGO:00346221530.062
spermatid developmentGO:0007286980.062
spermatogenesisGO:00072832000.062
posttranscriptional regulation of gene expressionGO:00106081450.061
mitotic cell cycle checkpointGO:0007093880.060
male meiosis cytokinesisGO:0007112260.060
nucleoside metabolic processGO:00091161270.060
cellular protein localizationGO:00346131600.060
protein modification processGO:00362114380.058
organelle localizationGO:00516401480.057
regulation of organelle organizationGO:00330431960.056
negative regulation of gene expressionGO:00106293870.056
regulation of catalytic activityGO:00507901850.056
cell cycle checkpointGO:0000075950.055
positive regulation of nitrogen compound metabolic processGO:00511733540.055
protein complex biogenesisGO:00702712010.055
regulation of cellular localizationGO:00603411360.055
regulation of transportGO:00510491810.054
cellular response to dna damage stimulusGO:00069742230.053
Yeast
chromosome organizationGO:00512763600.053
Yeast
catabolic processGO:00090564090.052
developmental maturationGO:00217001720.051
intracellular protein transportGO:00068861040.050
phosphorylationGO:00163102940.050
posttranscriptional gene silencing by rnaGO:0035194450.050
positive regulation of macromolecule biosynthetic processGO:00105572830.049
negative regulation of transcription dna templatedGO:00458922370.049
positive regulation of rna metabolic processGO:00512542710.048
intracellular transportGO:00469072280.047
purine ribonucleotide catabolic processGO:00091541090.045
larval developmentGO:00021641040.045
gastrulationGO:0007369700.045
regulation of chromosome segregationGO:0051983320.045
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.045
response to oxygen containing compoundGO:19017002000.045
karyogamyGO:000074140.044
regulation of molecular functionGO:00650092170.044
positive regulation of biosynthetic processGO:00098913160.044
regulation of protein catabolic processGO:0042176550.044
gene silencingGO:00164581380.043
mitotic sister chromatid segregationGO:0000070870.043
negative regulation of cellular protein metabolic processGO:0032269850.043
establishment of organelle localizationGO:00516561220.043
protein modification by small protein conjugationGO:0032446790.041
single organism intracellular transportGO:19025822070.041
macromolecule catabolic processGO:00090571610.041
taxisGO:00423303040.041
spindle assembly involved in female meiosis iGO:000705750.040
response to radiationGO:00093141550.040
regulation of oocyte developmentGO:0060281270.039
meiosis iGO:0007127590.038
digestive system developmentGO:00551231490.038
reproductive system developmentGO:0061458740.037
meiotic chromosome separationGO:005130780.035
camera type eye developmentGO:004301040.035
snrna processingGO:0016180140.035
regulation of mitotic metaphase anaphase transitionGO:0030071260.035
cytoplasm organizationGO:0007028640.035
axonogenesisGO:00074092900.034
rna processingGO:00063961470.034
Fly
regulation of nucleocytoplasmic transportGO:0046822350.033
female meiotic divisionGO:0007143700.033
asymmetric cell divisionGO:0008356370.033
nuclear transportGO:0051169720.033
dendrite morphogenesisGO:00488131990.033
centrosome separationGO:0051299200.032
mrna metabolic processGO:00160711240.032
Fly
metaphase anaphase transition of cell cycleGO:0044784280.032
regulation of cellular catabolic processGO:00313291570.032
aromatic compound catabolic processGO:00194391660.031
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.031
response to ionizing radiationGO:0010212320.031
regulation of cellular component biogenesisGO:00440872010.030
regulation of metaphase anaphase transition of cell cycleGO:1902099260.030
vesicle mediated transportGO:00161923810.030
protein importGO:0017038550.030
chemotaxisGO:00069352490.029
regulation of multi organism processGO:00439001310.029
reproductive structure developmentGO:0048608740.029
positive regulation of proteolysisGO:0045862520.029
meiotic nuclear divisionGO:00071261510.029
protein import into nucleusGO:0006606510.029
ribose phosphate metabolic processGO:00196931450.029
protein maturationGO:0051604710.029
maintenance of locationGO:0051235730.028
regulation of mitotic sister chromatid segregationGO:0033047280.028
single organism nuclear importGO:1902593510.028
nucleoside catabolic processGO:00091641120.028
nucleocytoplasmic transportGO:0006913720.027
actin filament based processGO:00300292200.027
cell motilityGO:00488702510.027
reproductive behaviorGO:00190981220.027
chromosome condensationGO:0030261410.027
purine containing compound metabolic processGO:00725211550.027
rna 3 end processingGO:0031123450.027
cell deathGO:00082192790.026
spermatid differentiationGO:00485151140.026
positive regulation of catabolic processGO:00098961050.026
cellular protein complex disassemblyGO:0043624350.026
nuclear importGO:0051170510.026
proteasomal protein catabolic processGO:0010498590.025
regulation of phosphorus metabolic processGO:00511742100.025
apoptotic processGO:00069151590.025
telencephalon developmentGO:002153720.024
negative regulation of cell divisionGO:0051782170.024
protein transportGO:00150311550.024
regulation of nuclear divisionGO:0051783580.024
syncytial blastoderm mitotic cell cycleGO:0035186210.024
regulation of programmed cell deathGO:00430671520.024
regulation of transferase activityGO:0051338580.023
digestive tract developmentGO:00485651490.023
intracellular signal transductionGO:00355563000.023
muscle cell differentiationGO:00426921030.023
protein targetingGO:0006605640.023
regulation of microtubule cytoskeleton organizationGO:0070507410.022
negative regulation of signal transductionGO:00099682060.022
protein targeting to nucleusGO:0044744510.022
g2 dna damage checkpointGO:0031572690.022
glycosyl compound metabolic processGO:19016571270.022
mitotic cell cycle embryonicGO:0045448380.022
ribonucleoside monophosphate catabolic processGO:0009158390.022
small molecule metabolic processGO:00442813050.022
cellular macromolecule catabolic processGO:00442651360.022
negative regulation of chromosome segregationGO:0051985140.021
protein localization to organelleGO:0033365820.021
pole plasm mrna localizationGO:0019094490.021
mitotic sister chromatid separationGO:0051306300.021
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.021
snrna metabolic processGO:0016073140.021
regulation of nervous system developmentGO:00519602480.021
regulation of reproductive processGO:2000241540.021
dna integrity checkpointGO:0031570810.021
mitotic dna damage checkpointGO:0044773740.021
axon guidanceGO:00074112330.020
neuron projection guidanceGO:00974852410.020
negative regulation of protein processingGO:0010955310.020
wnt signaling pathwayGO:0016055980.020
purine nucleotide metabolic processGO:00061631460.020
negative regulation of proteolysisGO:0045861310.020
regulation of mitotic sister chromatid separationGO:0010965280.020
establishment of cell polarityGO:0030010400.020
regulation of sister chromatid segregationGO:0033045280.019
regulation of establishment of protein localizationGO:0070201610.019
homeostatic processGO:00425921990.019
purine ribonucleoside metabolic processGO:00461281270.019
positive regulation of transportGO:0051050920.019
translationGO:0006412690.019
negative regulation of protein metabolic processGO:0051248850.019
cell migrationGO:00164772380.019
establishment of protein localizationGO:00451841630.019
positive regulation of nucleocytoplasmic transportGO:0046824240.018
nucleoside phosphate metabolic processGO:00067531620.018
establishment or maintenance of cytoskeleton polarityGO:0030952440.018
atp metabolic processGO:0046034490.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
snrna 3 end processingGO:0034472140.018
stem cell divisionGO:0017145690.018
nuclear transcribed mrna catabolic processGO:0000956240.018
central nervous system developmentGO:00074172010.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.017
establishment or maintenance of cell polarityGO:00071631670.017
metaphase anaphase transition of mitotic cell cycleGO:0007091280.017
spindle checkpointGO:0031577110.017
protein complex disassemblyGO:0043241360.017
cellular protein catabolic processGO:0044257830.017
positive regulation of gene expressionGO:00106282900.017
regulation of cell deathGO:00109411730.017
male pronucleus assemblyGO:003503960.017
organonitrogen compound metabolic processGO:19015643180.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
purine containing compound catabolic processGO:00725231120.017
negative regulation of programmed cell deathGO:0043069720.017
regulation of anatomical structure sizeGO:00900661630.016
regulation of phosphorylationGO:00423251470.016
dendrite developmentGO:00163582040.016
sperm individualizationGO:0007291480.016
forebrain developmentGO:003090020.016
regulation of apoptotic processGO:00429811300.016
positive regulation of transcription dna templatedGO:00458932660.016
nucleoside triphosphate metabolic processGO:00091411200.016
posttranscriptional gene silencingGO:0016441460.016
organophosphate metabolic processGO:00196371950.016
regulation of translationGO:0006417560.016
gland morphogenesisGO:00226121450.016
positive regulation of phosphorylationGO:0042327870.016
mitotic spindle assembly checkpointGO:0007094110.016
positive regulation of nervous system developmentGO:0051962690.016
cellular response to organic substanceGO:00713101320.015
dna damage checkpointGO:0000077780.015
centriole replicationGO:0007099240.015
regulation of cell developmentGO:00602842150.015
positive regulation of proteasomal protein catabolic processGO:1901800200.015
multicellular organismal agingGO:00102591400.015
cytoskeleton dependent cytokinesisGO:0061640810.015
organophosphate catabolic processGO:00464341120.015
dna conformation changeGO:00711031050.015
regulation of peptidase activityGO:0052547390.015
cellular nitrogen compound catabolic processGO:00442701650.015
positive regulation of phosphate metabolic processGO:00459371390.015
transcription from rna polymerase ii promoterGO:00063663680.015
spindle assembly involved in female meiosisGO:0007056140.015
chromatin modificationGO:00165681470.015
heterocycle catabolic processGO:00467001660.015
regulation of protein localizationGO:0032880760.015
negative regulation of growthGO:0045926840.015
regulation of intracellular protein transportGO:0033157460.015
regulation of intracellular transportGO:0032386640.015
regulation of hydrolase activityGO:0051336970.015
intracellular mrna localizationGO:0008298660.015
muscle structure developmentGO:00610612240.015
body morphogenesisGO:001017120.014
maintenance of protein location in cellGO:0032507260.014
endomembrane system organizationGO:00102561190.014
response to organic substanceGO:00100332840.014
protein phosphorylationGO:00064681690.014
regulation of protein modification processGO:00313991120.014
regulation of embryonic developmentGO:0045995680.014
tube morphogenesisGO:00352391910.013
actin cytoskeleton organizationGO:00300362060.013
establishment of rna localizationGO:0051236470.013
programmed cell deathGO:00125012570.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
organic cyclic compound catabolic processGO:19013611680.013
anatomical structure homeostasisGO:0060249970.013
negative regulation of cell communicationGO:00106482230.013
dna methylation or demethylationGO:004472840.013
sex differentiationGO:0007548810.012
phagocytosisGO:00069092150.012
protein catabolic processGO:00301631010.012
organonitrogen compound catabolic processGO:19015651280.012
response to starvationGO:0042594970.012
regulation of cytoplasmic transportGO:1903649470.012
nitrogen compound transportGO:0071705850.012
positive regulation of synapse assemblyGO:0051965290.012
lipid storageGO:0019915380.012
positive regulation of developmental processGO:00510941430.012
protein processingGO:0016485680.012
mrna catabolic processGO:0006402330.012
negative regulation of cell differentiationGO:00455961430.012
mitotic spindle checkpointGO:0071174110.012
dna alkylationGO:000630540.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
dna recombinationGO:0006310320.011
mitotic spindle stabilizationGO:004314860.011
pole plasm rna localizationGO:0007316520.011
development of primary sexual characteristicsGO:0045137500.011
macromolecular complex disassemblyGO:0032984370.011
positive regulation of molecular functionGO:00440931360.011
cell maturationGO:00484691440.011
negative regulation of developmental processGO:00510932010.011
regulation of phosphate metabolic processGO:00192202100.011
regulation of cellular amine metabolic processGO:003323830.011
regulation of synapse structure and activityGO:00508031280.011
peripheral nervous system developmentGO:0007422520.011
intracellular mrna localization involved in pattern specification processGO:0060810560.011
regulation of neuron differentiationGO:00456641030.011
regulation of cytoskeleton organizationGO:0051493890.011
regulation of cellular protein catabolic processGO:1903362440.011
mrna 3 end processingGO:0031124280.011
regulation of protein processingGO:0070613320.011
digestive tract morphogenesisGO:00485461270.011
positive regulation of cell motilityGO:200014730.011
microtubule polymerization or depolymerizationGO:0031109390.011
meiotic cytokinesisGO:0033206330.011
salivary gland histolysisGO:0035070880.010
positive regulation of protein metabolic processGO:00512471280.010
receptor mediated endocytosisGO:0006898210.010
head developmentGO:00603221350.010
positive regulation of phosphorus metabolic processGO:00105621390.010
regulation of protein complex disassemblyGO:0043244290.010
lipid localizationGO:0010876540.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
ribonucleoprotein complex assemblyGO:0022618230.010
cellular protein complex assemblyGO:0043623710.010
single organism biosynthetic processGO:00447112060.010
regulation of cellular ketone metabolic processGO:001056530.010

lds disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.110
disease of cellular proliferationDOID:1456600.110
organ system cancerDOID:005068600.110
musculoskeletal system cancerDOID:006010000.014
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
musculoskeletal system diseaseDOID:1700.012