IMP: Integrative Multi-species Prediction

Drosophila melanogaster

221 known processes

csw (Dmel_CG3954)

corkscrew

(Aliases: l(1)G0170,l(1)csw,SHP-2,Dmel\CG3954,19-106,E(sev)1A,Shp2/csw,anon-WO03040301.219,anon-WO03040301.207,EG:BACN25G24.2,l(1)GA114,Csw/Shp2,l(1)2Db,CSW,CG3954,Csw,anon-WO03040301.209,l(1)2Dd)

FLYBASE: FBgn0000382
Entrez: 45278
UniProtKB: P29349
UniProtKB: M9PGI1
UniProtKB: L7XAI0

Process Predictions
Disease Predictions

csw biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regionalization	GO:0003002	416	0.995
photoreceptor cell differentiation	GO:0046530	170	0.994
tube morphogenesis	GO:0035239	191	0.990	Zebrafish
blastoderm segmentation	GO:0007350	159	0.978
formation of primary germ layer	GO:0001704	24	0.973
eye photoreceptor cell differentiation	GO:0001754	145	0.962
gastrulation	GO:0007369	70	0.956	Zebrafish
imaginal disc derived wing morphogenesis	GO:0007476	337	0.949
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.948
regulation of photoreceptor cell differentiation	GO:0046532	34	0.944
appendage morphogenesis	GO:0035107	397	0.936
eye development	GO:0001654	323	0.930
axis specification	GO:0009798	167	0.920
segmentation	GO:0035282	207	0.917
epithelial cell differentiation	GO:0030855	322	0.912
compound eye photoreceptor development	GO:0042051	78	0.908
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.900
chorion containing eggshell formation	GO:0007304	105	0.888
compound eye photoreceptor cell differentiation	GO:0001751	140	0.883
post embryonic appendage morphogenesis	GO:0035120	385	0.876
compound eye morphogenesis	GO:0001745	249	0.866
sensory organ morphogenesis	GO:0090596	260	0.862
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.858
appendage development	GO:0048736	401	0.857
imaginal disc derived appendage development	GO:0048737	399	0.852
compound eye development	GO:0048749	307	0.843
tube development	GO:0035295	244	0.820	Zebrafish
compound eye photoreceptor fate commitment	GO:0001752	36	0.802
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.792
regulation of cell development	GO:0060284	215	0.765
epithelium migration	GO:0090132	148	0.762
regulation of multicellular organismal development	GO:2000026	414	0.746
wing disc morphogenesis	GO:0007472	344	0.721
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.717
regulation of neurogenesis	GO:0050767	158	0.716
cellular response to chemical stimulus	GO:0070887	199	0.703
immune system development	GO:0002520	57	0.695	Mouse
cardioblast differentiation	GO:0010002	20	0.686
transcription from rna polymerase ii promoter	GO:0006366	368	0.670
response to organic substance	GO:0010033	284	0.660
stem cell differentiation	GO:0048863	117	0.658
positive regulation of gene expression	GO:0010628	290	0.648
cell proliferation	GO:0008283	299	0.645	Human Mouse
imaginal disc derived wing vein specification	GO:0007474	48	0.645
epithelial cell development	GO:0002064	274	0.640
anterior posterior pattern specification	GO:0009952	136	0.624
olfactory behavior	GO:0042048	97	0.622
eye photoreceptor cell fate commitment	GO:0042706	37	0.612
tissue migration	GO:0090130	155	0.577
terminal region determination	GO:0007362	25	0.575
digestive tract morphogenesis	GO:0048546	127	0.572	Zebrafish
epithelial cell migration	GO:0010631	148	0.571
r7 cell differentiation	GO:0045466	43	0.570
eggshell formation	GO:0030703	105	0.566
circulatory system development	GO:0072359	82	0.556	Human Zebrafish
positive regulation of photoreceptor cell differentiation	GO:0046534	12	0.551
central nervous system development	GO:0007417	201	0.541
r7 cell fate commitment	GO:0007465	12	0.532
cell motility	GO:0048870	251	0.520
establishment of tissue polarity	GO:0007164	87	0.517
morphogenesis of a polarized epithelium	GO:0001738	93	0.489
cardiac cell fate commitment	GO:0060911	17	0.484
digestive tract development	GO:0048565	149	0.477	Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.471
eye morphogenesis	GO:0048592	260	0.467
programmed cell death	GO:0012501	257	0.461
death	GO:0016265	284	0.458
dorsal ventral pattern formation	GO:0009953	133	0.455
ras protein signal transduction	GO:0007265	88	0.453
mesoderm development	GO:0007498	78	0.445
columnar cuboidal epithelial cell development	GO:0002066	249	0.438
positive regulation of transcription dna templated	GO:0045893	266	0.425
wnt signaling pathway	GO:0016055	98	0.423
embryonic morphogenesis	GO:0048598	206	0.418	Zebrafish
cell fate specification	GO:0001708	71	0.415
cellular ketone metabolic process	GO:0042180	24	0.413
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.409
digestive system development	GO:0055123	149	0.403	Zebrafish
embryonic pattern specification	GO:0009880	174	0.380
establishment of ommatidial planar polarity	GO:0042067	49	0.364
response to endogenous stimulus	GO:0009719	119	0.361
positive regulation of rna metabolic process	GO:0051254	271	0.361
cardiovascular system development	GO:0072358	82	0.347	Human Zebrafish
regulation of phosphorylation	GO:0042325	147	0.340	Human Mouse
mesoderm formation	GO:0001707	21	0.337
neuron fate commitment	GO:0048663	50	0.335
eye photoreceptor cell development	GO:0042462	81	0.329
negative regulation of signaling	GO:0023057	219	0.328	Mouse
regulation of cell proliferation	GO:0042127	163	0.325	Human Mouse
heart development	GO:0007507	82	0.318	Human Zebrafish
positive regulation of r7 cell differentiation	GO:0045678	7	0.317
tissue morphogenesis	GO:0048729	297	0.314
regulation of organ morphogenesis	GO:2000027	78	0.312
cell migration involved in gastrulation	GO:0042074	9	0.312
mesoderm morphogenesis	GO:0048332	22	0.306
regulation of r7 cell differentiation	GO:0045676	15	0.299
positive regulation of biosynthetic process	GO:0009891	316	0.299
epithelial tube morphogenesis	GO:0060562	88	0.296	Zebrafish
positive regulation of cellular biosynthetic process	GO:0031328	316	0.295
axon development	GO:0061564	297	0.291	Mouse
cellular response to fibroblast growth factor stimulus	GO:0044344	10	0.282
head development	GO:0060322	135	0.281	Human
hemocyte differentiation	GO:0042386	38	0.280
negative regulation of cellular biosynthetic process	GO:0031327	277	0.275
growth	GO:0040007	359	0.273	Zebrafish Mouse
forebrain development	GO:0030900	2	0.272
eye antennal disc development	GO:0035214	60	0.272
embryo development ending in birth or egg hatching	GO:0009792	152	0.272	Zebrafish
brain development	GO:0007420	120	0.271	Human
establishment or maintenance of cell polarity	GO:0007163	167	0.269
morphogenesis of an epithelium	GO:0002009	276	0.255
positive regulation of macromolecule metabolic process	GO:0010604	405	0.250	Mouse
positive regulation of signal transduction	GO:0009967	223	0.244	Human Mouse
photoreceptor cell development	GO:0042461	96	0.240
lymph gland development	GO:0048542	28	0.235
cognition	GO:0050890	141	0.235
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.233
small molecule metabolic process	GO:0044281	305	0.233
regulation of cell differentiation	GO:0045595	302	0.224
urogenital system development	GO:0001655	72	0.221
small gtpase mediated signal transduction	GO:0007264	88	0.221
oocyte development	GO:0048599	124	0.218
localization of cell	GO:0051674	257	0.217
muscle structure development	GO:0061061	224	0.213
positive regulation of response to stimulus	GO:0048584	323	0.204	Human Mouse
reproductive structure development	GO:0048608	74	0.201	Human
torc1 signaling	GO:0038202	12	0.191
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.188
erk1 and erk2 cascade	GO:0070371	39	0.186	Human Mouse
photoreceptor cell fate commitment	GO:0046552	41	0.181
negative regulation of signal transduction	GO:0009968	206	0.180	Mouse
establishment of localization in cell	GO:0051649	402	0.179	Mouse
ameboidal type cell migration	GO:0001667	151	0.179
single organism behavior	GO:0044708	391	0.179
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.178
apoptotic process	GO:0006915	159	0.178
regulation of cell death	GO:0010941	173	0.175
regulation of apoptotic process	GO:0042981	130	0.171
tracheal outgrowth open tracheal system	GO:0007426	18	0.169
cell migration	GO:0016477	238	0.168
leg disc development	GO:0035218	92	0.168
cellular protein modification process	GO:0006464	438	0.168
renal tubule development	GO:0061326	64	0.161
regulation of phosphorus metabolic process	GO:0051174	210	0.160	Human Mouse
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.158
embryonic organ development	GO:0048568	50	0.153	Zebrafish
anatomical structure homeostasis	GO:0060249	97	0.153
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.150
regulation of kinase activity	GO:0043549	53	0.149	Mouse
somatic muscle development	GO:0007525	66	0.147
negative regulation of programmed cell death	GO:0043069	72	0.146
imaginal disc pattern formation	GO:0007447	91	0.145
regulation of embryonic development	GO:0045995	68	0.145
muscle organ development	GO:0007517	127	0.144
mapk cascade	GO:0000165	107	0.143	Human Mouse
establishment of planar polarity	GO:0001736	87	0.142
regulation of cellular ketone metabolic process	GO:0010565	3	0.142
establishment of organelle localization	GO:0051656	122	0.142
notch signaling pathway	GO:0007219	120	0.139
single organism cellular localization	GO:1902580	180	0.139
positive regulation of cellular protein metabolic process	GO:0032270	118	0.138	Mouse
oxoacid metabolic process	GO:0043436	103	0.137
regulation of cell fate specification	GO:0042659	27	0.137
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.136	Mouse
negative regulation of developmental process	GO:0051093	201	0.136
phosphorylation	GO:0016310	294	0.133	Human Mouse
positive regulation of multicellular organismal process	GO:0051240	143	0.131
regulation of macroautophagy	GO:0016241	15	0.131
positive regulation of cell proliferation	GO:0008284	47	0.131	Human
imaginal disc derived leg morphogenesis	GO:0007480	80	0.130
signal transduction by phosphorylation	GO:0023014	107	0.130	Human Mouse
single organism biosynthetic process	GO:0044711	206	0.127
negative regulation of smoothened signaling pathway	GO:0045879	16	0.126
wing and notum subfield formation	GO:0035309	13	0.121
oocyte axis specification	GO:0007309	108	0.120
erbb signaling pathway	GO:0038127	58	0.120
stem cell development	GO:0048864	79	0.119
positive regulation of phosphate metabolic process	GO:0045937	139	0.117	Mouse
renal system development	GO:0072001	72	0.117
regulation of ras protein signal transduction	GO:0046578	93	0.117
cell fate determination	GO:0001709	91	0.115
neurological system process	GO:0050877	358	0.113
sex differentiation	GO:0007548	81	0.109	Human
chorion containing eggshell pattern formation	GO:0030381	11	0.109
organic acid metabolic process	GO:0006082	103	0.106
sensory perception	GO:0007600	196	0.105
anterior posterior axis specification	GO:0009948	109	0.103
negative regulation of cellular metabolic process	GO:0031324	382	0.102	Human Mouse
chemosensory behavior	GO:0007635	106	0.102
negative regulation of response to extracellular stimulus	GO:0032105	6	0.100
malpighian tubule development	GO:0072002	64	0.098
developmental growth	GO:0048589	280	0.098	Zebrafish Mouse
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.098
positive regulation of rna biosynthetic process	GO:1902680	266	0.097
lateral inhibition	GO:0046331	206	0.097
regulation of erk1 and erk2 cascade	GO:0070372	39	0.096	Human Mouse
cell cycle phase transition	GO:0044770	140	0.096	Human
eye antennal disc morphogenesis	GO:0007455	34	0.096
tripartite regional subdivision	GO:0007351	103	0.096
regulation of cell fate commitment	GO:0010453	29	0.095
negative regulation of multicellular organismal process	GO:0051241	142	0.095	Mouse
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.094
regulation of transferase activity	GO:0051338	58	0.094	Mouse
chromosome organization	GO:0051276	360	0.094
regulation of phosphate metabolic process	GO:0019220	210	0.094	Human Mouse
mitotic cell cycle phase transition	GO:0044772	138	0.093	Human
gland development	GO:0048732	191	0.092
retina development in camera type eye	GO:0060041	4	0.091
carboxylic acid metabolic process	GO:0019752	92	0.091
torso signaling pathway	GO:0008293	21	0.091
imaginal disc derived leg segmentation	GO:0036011	26	0.089
negative regulation of response to stimulus	GO:0048585	258	0.088	Mouse
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.088
negative regulation of cell differentiation	GO:0045596	143	0.087
regulation of proteasomal protein catabolic process	GO:0061136	39	0.087
spermatogenesis	GO:0007283	200	0.087
male gamete generation	GO:0048232	201	0.086
embryonic axis specification	GO:0000578	107	0.085
regulation of protein modification process	GO:0031399	112	0.085	Human Mouse
positive regulation of molecular function	GO:0044093	136	0.085	Mouse
regulation of intracellular signal transduction	GO:1902531	236	0.084	Human Mouse
organelle localization	GO:0051640	148	0.084
negative regulation of biosynthetic process	GO:0009890	277	0.083
limb development	GO:0060173	1	0.083
negative regulation of apoptotic process	GO:0043066	63	0.081
negative regulation of macroautophagy	GO:0016242	6	0.081
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.080
cell adhesion	GO:0007155	136	0.080	Human Mouse
immune system process	GO:0002376	347	0.080	Mouse
exocrine system development	GO:0035272	162	0.079
leg disc morphogenesis	GO:0007478	80	0.079
sensory perception of sound	GO:0007605	56	0.078
endodermal cell fate commitment	GO:0001711	3	0.078
compound eye cone cell fate commitment	GO:0042676	5	0.078
dna metabolic process	GO:0006259	227	0.077
amine metabolic process	GO:0009308	12	0.076
segment specification	GO:0007379	33	0.075
multicellular organism growth	GO:0035264	46	0.074	Mouse
compound eye retinal cell programmed cell death	GO:0046667	23	0.074
bmp signaling pathway	GO:0030509	27	0.073
regulation of cellular amine metabolic process	GO:0033238	3	0.073
negative regulation of protein phosphorylation	GO:0001933	17	0.072	Human Mouse
chaeta development	GO:0022416	97	0.072
larval development	GO:0002164	104	0.072
organonitrogen compound metabolic process	GO:1901564	318	0.072
ovarian follicle cell development	GO:0030707	248	0.071
regulation of localization	GO:0032879	275	0.071	Human Mouse
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.071
female genitalia development	GO:0030540	6	0.070
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.070
compound eye cone cell differentiation	GO:0042675	13	0.069
rho protein signal transduction	GO:0007266	14	0.069
negative regulation of cell cycle	GO:0045786	116	0.069
axis elongation	GO:0003401	3	0.068	Zebrafish
regulation of molecular function	GO:0065009	217	0.067	Mouse
regulation of mitotic cell cycle	GO:0007346	190	0.067	Human Mouse
cell death	GO:0008219	279	0.066
regulation of cellular protein metabolic process	GO:0032268	243	0.066	Human Mouse
regulation of nervous system development	GO:0051960	248	0.066
regulation of programmed cell death	GO:0043067	152	0.065
female sex differentiation	GO:0046660	20	0.065
regulation of eye photoreceptor cell development	GO:0042478	13	0.065
chaeta morphogenesis	GO:0008407	42	0.064
cell maturation	GO:0048469	144	0.064
convergent extension	GO:0060026	2	0.064	Zebrafish
anterior posterior axis specification embryo	GO:0008595	103	0.064
response to oxidative stress	GO:0006979	86	0.063
embryonic heart tube development	GO:0035050	22	0.062	Zebrafish
regulation of protein metabolic process	GO:0051246	256	0.062	Human Mouse
endoderm formation	GO:0001706	3	0.062
organic substance transport	GO:0071702	257	0.061	Human Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.059
regulation of cellular amino acid metabolic process	GO:0006521	0	0.059
negative regulation of rna biosynthetic process	GO:1902679	240	0.058
fusion cell fate specification	GO:0035156	4	0.058
hematopoietic or lymphoid organ development	GO:0048534	57	0.057	Mouse
nephrocyte differentiation	GO:0061319	12	0.057
positive regulation of cell communication	GO:0010647	250	0.057	Human Mouse
regulation of system process	GO:0044057	36	0.057	Mouse
negative regulation of epithelial cell migration	GO:0010633	1	0.056
cellular amino acid metabolic process	GO:0006520	61	0.056
mesodermal cell migration	GO:0008078	7	0.055
regulation of erbb signaling pathway	GO:1901184	42	0.054
regulation of response to extracellular stimulus	GO:0032104	18	0.054
regulation of immune system process	GO:0002682	176	0.054	Mouse
border follicle cell migration	GO:0007298	113	0.054
cellular response to endogenous stimulus	GO:0071495	80	0.052
zygotic determination of anterior posterior axis embryo	GO:0007354	27	0.051
circulatory system process	GO:0003013	37	0.051
multi multicellular organism process	GO:0044706	123	0.050
cellular response to organic substance	GO:0071310	132	0.050
positive regulation of phosphorylation	GO:0042327	87	0.049	Mouse
oocyte differentiation	GO:0009994	145	0.049
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.049
mitotic sister chromatid segregation	GO:0000070	87	0.048
protein import	GO:0017038	55	0.048
learning or memory	GO:0007611	141	0.048
secretion by cell	GO:0032940	101	0.047	Mouse
positive regulation of developmental process	GO:0051094	143	0.047
sensory perception of mechanical stimulus	GO:0050954	72	0.047
camera type eye development	GO:0043010	4	0.047
reproductive system development	GO:0061458	74	0.047	Human
regulation of organ growth	GO:0046620	42	0.046
regulation of secretion	GO:0051046	44	0.046	Mouse
dorsal ventral axis specification	GO:0009950	66	0.046
dendrite development	GO:0016358	204	0.045
kidney morphogenesis	GO:0060993	3	0.044
regulation of anatomical structure morphogenesis	GO:0022603	242	0.044
regulation of hemocyte differentiation	GO:0045610	22	0.044
regulation of response to nutrient levels	GO:0032107	18	0.043
immune response	GO:0006955	246	0.043	Mouse
response to fibroblast growth factor	GO:0071774	10	0.043
regulation of protein phosphorylation	GO:0001932	64	0.043	Human Mouse
wing disc pattern formation	GO:0035222	66	0.042
single organism intracellular transport	GO:1902582	207	0.042	Mouse
specification of organ identity	GO:0010092	3	0.040
connective tissue development	GO:0061448	3	0.040
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.040
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.039
positive regulation of ras protein signal transduction	GO:0046579	43	0.039
open tracheal system development	GO:0007424	204	0.039
regulation of multicellular organism growth	GO:0040014	40	0.039	Mouse
axon guidance	GO:0007411	233	0.039
mitotic nuclear division	GO:0007067	213	0.038
germ band shortening	GO:0007390	19	0.037
peptidyl amino acid modification	GO:0018193	105	0.037	Human Mouse
cardioblast cell fate commitment	GO:0042684	14	0.037
protein modification by small protein conjugation	GO:0032446	79	0.037
developmental maturation	GO:0021700	172	0.037
vesicle mediated transport	GO:0016192	381	0.037
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.036
organ growth	GO:0035265	56	0.036	Mouse
positive regulation of signaling	GO:0023056	243	0.036	Human Mouse
endodermal cell differentiation	GO:0035987	3	0.036
hindgut morphogenesis	GO:0007442	58	0.036
meiotic cell cycle	GO:0051321	171	0.035
imaginal disc derived wing hair organization	GO:0035317	45	0.035
innate immune response	GO:0045087	144	0.035	Mouse
regulation of cell cycle process	GO:0010564	181	0.033	Human
positive regulation of cellular amine metabolic process	GO:0033240	0	0.033
regulation of map kinase activity	GO:0043405	17	0.033	Mouse
regulation of phosphatase activity	GO:0010921	3	0.033
response to ecdysone	GO:0035075	34	0.033
r3 r4 cell differentiation	GO:0048056	12	0.032
instar larval development	GO:0002168	55	0.032
epithelial cell type specification open tracheal system	GO:0035153	11	0.032
cellular response to growth factor stimulus	GO:0071363	30	0.032
protein complex biogenesis	GO:0070271	201	0.032
camp biosynthetic process	GO:0006171	17	0.031
developmental programmed cell death	GO:0010623	138	0.031
cardiocyte differentiation	GO:0035051	29	0.031
embryonic hindgut morphogenesis	GO:0048619	48	0.030
ribonucleoside catabolic process	GO:0042454	112	0.030
establishment of spindle localization	GO:0051293	22	0.030
gonad development	GO:0008406	50	0.030
intracellular signal transduction	GO:0035556	300	0.030	Human Mouse
negative regulation of gene expression	GO:0010629	387	0.030
positive regulation of intracellular signal transduction	GO:1902533	116	0.029	Human Mouse
regulation of compound eye photoreceptor development	GO:0045314	12	0.029
negative regulation of epithelial cell proliferation	GO:0050680	4	0.029
gland morphogenesis	GO:0022612	145	0.029
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.029
delamination	GO:0060232	8	0.029
negative regulation of cell communication	GO:0010648	223	0.028	Mouse
organ formation	GO:0048645	39	0.028
malpighian tubule morphogenesis	GO:0007443	44	0.028
protein catabolic process	GO:0030163	101	0.028
cell fate specification involved in pattern specification	GO:0060573	8	0.028
aging	GO:0007568	143	0.028
positive regulation of protein metabolic process	GO:0051247	128	0.028	Mouse
positive regulation of protein phosphorylation	GO:0001934	34	0.027	Mouse
negative regulation of erbb signaling pathway	GO:1901185	29	0.027
axonogenesis	GO:0007409	290	0.026	Mouse
single organism catabolic process	GO:0044712	228	0.026
negative regulation of cell cycle phase transition	GO:1901988	103	0.026
regulation of cellular catabolic process	GO:0031329	157	0.026
regulation of cellular response to growth factor stimulus	GO:0090287	13	0.025
regulation of ras gtpase activity	GO:0032318	38	0.025
regulation of cell cycle	GO:0051726	291	0.025	Human Mouse
signal transduction in response to dna damage	GO:0042770	3	0.025
regulation of actin filament bundle assembly	GO:0032231	8	0.025
eggshell chorion assembly	GO:0007306	66	0.025
neurotrophin signaling pathway	GO:0038179	2	0.024	Mouse
signal transduction downstream of smoothened	GO:0007227	5	0.024
macroautophagy	GO:0016236	42	0.024
regulation of notch signaling pathway	GO:0008593	100	0.024
negative regulation of cell death	GO:0060548	81	0.024
regulation of compound eye retinal cell programmed cell death	GO:0046669	18	0.024
negative regulation of mapk cascade	GO:0043409	23	0.024	Mouse
establishment of imaginal disc derived wing hair orientation	GO:0001737	24	0.023
negative regulation of transcription dna templated	GO:0045892	237	0.023
response to alcohol	GO:0097305	95	0.023
cellular response to hormone stimulus	GO:0032870	44	0.023	Human Mouse
kidney development	GO:0001822	3	0.023
mesenchymal cell differentiation	GO:0048762	1	0.023
negative regulation of response to nutrient levels	GO:0032108	6	0.023
cellular response to abiotic stimulus	GO:0071214	58	0.023
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.023
regulation of cellular protein catabolic process	GO:1903362	44	0.023
regulation of transport	GO:0051049	181	0.022	Human Mouse
gastrulation involving germ band extension	GO:0010004	36	0.022
regulation of organ formation	GO:0003156	3	0.022
positive regulation of kinase activity	GO:0033674	25	0.022	Mouse
morphogenesis of a branching epithelium	GO:0061138	45	0.022
protein modification process	GO:0036211	438	0.022
limb morphogenesis	GO:0035108	1	0.021
organic substance catabolic process	GO:1901575	308	0.021
regulation of anatomical structure size	GO:0090066	163	0.021
gastrulation with mouth forming first	GO:0001703	36	0.021
regulation of cellular component biogenesis	GO:0044087	201	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
regulation of protein kinase activity	GO:0045859	51	0.021	Mouse
positive regulation of ras gtpase activity	GO:0032320	36	0.021
development of primary sexual characteristics	GO:0045137	50	0.021
oocyte construction	GO:0007308	112	0.020
peptidyl lysine acetylation	GO:0018394	39	0.020
neuron projection guidance	GO:0097485	241	0.020
negative regulation of cellular protein metabolic process	GO:0032269	85	0.020	Human Mouse
regulation of intracellular transport	GO:0032386	64	0.020	Mouse
positive regulation of protein kinase activity	GO:0045860	25	0.020	Mouse
actin filament organization	GO:0007015	126	0.020
renal tubule morphogenesis	GO:0061333	44	0.020
cellular response to nutrient levels	GO:0031669	62	0.020
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.020
regulation of response to stress	GO:0080134	200	0.020
regulation of neuron differentiation	GO:0045664	103	0.020
positive regulation of transport	GO:0051050	92	0.019	Human Mouse
negative regulation of cell cell adhesion	GO:0022408	8	0.019
respiratory system development	GO:0060541	213	0.019
peptidyl threonine phosphorylation	GO:0018107	2	0.019
muscle cell fate commitment	GO:0042693	14	0.019
protein transport	GO:0015031	155	0.019	Mouse
negative regulation of rna metabolic process	GO:0051253	251	0.019
skin development	GO:0043588	65	0.019
response to anesthetic	GO:0072347	9	0.019
homeostatic process	GO:0042592	199	0.019	Mouse
positive regulation of mapk cascade	GO:0043410	63	0.019	Mouse
response to insulin	GO:0032868	29	0.019	Human
regulation of catalytic activity	GO:0050790	185	0.019	Mouse
regulation of smoothened signaling pathway	GO:0008589	28	0.019
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.019
hindgut development	GO:0061525	58	0.019
regulation of cell cycle phase transition	GO:1901987	130	0.019	Human
ovarian follicle cell migration	GO:0007297	121	0.019
biological adhesion	GO:0022610	138	0.019	Human Mouse
cell aging	GO:0007569	2	0.018
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.018
chromatin organization	GO:0006325	207	0.018
cell fate commitment involved in pattern specification	GO:0060581	31	0.018
actin filament bundle assembly	GO:0051017	26	0.018
cell division	GO:0051301	248	0.018
developmental induction	GO:0031128	3	0.018
multicellular organismal reproductive behavior	GO:0033057	110	0.018
response to ionizing radiation	GO:0010212	32	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018	Human Mouse
non sensory hair organization	GO:0035316	47	0.018
positive regulation of phosphorus metabolic process	GO:0010562	139	0.018	Mouse
regulation of meiotic cell cycle	GO:0051445	9	0.018
hemopoiesis	GO:0030097	46	0.017	Mouse
antennal development	GO:0007469	25	0.017
regulation of establishment of protein localization	GO:0070201	61	0.017	Mouse
establishment of protein localization	GO:0045184	163	0.017	Mouse
cellular response to oxygen containing compound	GO:1901701	79	0.017	Human
retinal cell programmed cell death	GO:0046666	25	0.017
muscle tissue development	GO:0060537	30	0.017
body morphogenesis	GO:0010171	2	0.017	Human
associative learning	GO:0008306	65	0.017
regulation of heart morphogenesis	GO:2000826	3	0.017
convergent extension involved in gastrulation	GO:0060027	2	0.017	Zebrafish
negative regulation of wnt signaling pathway	GO:0030178	28	0.017
dorsal appendage formation	GO:0046843	47	0.017
monocarboxylic acid transport	GO:0015718	3	0.016
cellular response to extracellular stimulus	GO:0031668	64	0.016
regulation of epidermal growth factor activated receptor activity	GO:0007176	4	0.016
sulfur compound metabolic process	GO:0006790	59	0.016
wing disc dorsal ventral pattern formation	GO:0048190	47	0.016
protein localization	GO:0008104	284	0.016	Mouse
response to bacterium	GO:0009617	198	0.016
negative regulation of phosphate metabolic process	GO:0045936	45	0.016	Human Mouse
response to growth factor	GO:0070848	31	0.016
negative regulation of epidermal growth factor activated receptor activity	GO:0007175	3	0.016
oocyte localization involved in germarium derived egg chamber formation	GO:0030720	12	0.016
regulation of protein export from nucleus	GO:0046825	3	0.015	Mouse
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
embryonic hemopoiesis	GO:0035162	26	0.015
regulation of gtp catabolic process	GO:0033124	44	0.015
response to hormone	GO:0009725	45	0.015	Human Mouse
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.015
regulation of epithelial cell proliferation	GO:0050678	4	0.015
r3 r4 cell fate commitment	GO:0007464	10	0.015
cell cycle arrest	GO:0007050	4	0.015

csw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of cellular proliferation	DOID:14566	0.104	Human
disease of anatomical entity	DOID:7	0.051
organ system cancer	DOID:0050686	0.022	Human
cancer	DOID:162	0.022	Human

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