IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

uex (Dmel_CG42595)

unextended

(Aliases: l(2)EMS34-7,l(2R)EMS45-73,GroupIII,CG40084,CG42595,l(2)IR3,IR3,l(2)41Ad,CR41594,Dmel\CG42595,41Ad,l(2Rh)IR3,EMS45-73,Dmel_CR41594,Dmel_CG40084,l(2R)A')

FLYBASE: FBgn0262124
Entrez: 5740320

Process Predictions
Disease Predictions

uex biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
nuclear division	GO:0000280	332	0.270
organelle fission	GO:0048285	340	0.210
leg disc development	GO:0035218	92	0.120
regulation of organelle organization	GO:0033043	196	0.078
protein modification process	GO:0036211	438	0.074
regulation of cell cycle	GO:0051726	291	0.070
regulation of gene expression epigenetic	GO:0040029	128	0.068
regulation of cell cycle process	GO:0010564	181	0.061
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.058
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.058
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.057
regulation of cell division	GO:0051302	72	0.053
sensory organ morphogenesis	GO:0090596	260	0.052
negative regulation of cell communication	GO:0010648	223	0.050
cell cycle checkpoint	GO:0000075	95	0.047
embryonic development via the syncytial blastoderm	GO:0001700	148	0.046
body morphogenesis	GO:0010171	2	0.046
negative regulation of organelle organization	GO:0010639	56	0.044
wnt signaling pathway	GO:0016055	98	0.044
gene silencing	GO:0016458	138	0.044
protein localization	GO:0008104	284	0.043
cellular protein modification process	GO:0006464	438	0.042
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.042
cell proliferation	GO:0008283	299	0.039
covalent chromatin modification	GO:0016569	106	0.039
reproductive behavior	GO:0019098	122	0.038
positive regulation of response to stimulus	GO:0048584	323	0.036
single organism behavior	GO:0044708	391	0.036
transcription from rna polymerase ii promoter	GO:0006366	368	0.036
meiotic nuclear division	GO:0007126	151	0.036
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.035
central nervous system development	GO:0007417	201	0.035
protein import	GO:0017038	55	0.035
chromatin organization	GO:0006325	207	0.034
response to organic substance	GO:0010033	284	0.034
negative regulation of signal transduction	GO:0009968	206	0.032
positive regulation of cellular biosynthetic process	GO:0031328	316	0.032
salivary gland morphogenesis	GO:0007435	145	0.032
response to ecdysone	GO:0035075	34	0.032
leg disc morphogenesis	GO:0007478	80	0.031
response to wounding	GO:0009611	94	0.031
regulation of cellular ketone metabolic process	GO:0010565	3	0.030
apoptotic process	GO:0006915	159	0.029
monocarboxylic acid transport	GO:0015718	3	0.028
negative regulation of biosynthetic process	GO:0009890	277	0.028
cell death	GO:0008219	279	0.028
positive regulation of biosynthetic process	GO:0009891	316	0.027
appendage morphogenesis	GO:0035107	397	0.026
cellular response to hormone stimulus	GO:0032870	44	0.026
phosphorylation	GO:0016310	294	0.025
cellular response to oxygen containing compound	GO:1901701	79	0.025
positive regulation of signal transduction	GO:0009967	223	0.025
carbohydrate metabolic process	GO:0005975	82	0.025
negative regulation of rna biosynthetic process	GO:1902679	240	0.024
taxis	GO:0042330	304	0.024
histolysis	GO:0007559	102	0.023
response to alcohol	GO:0097305	95	0.023
regulation of cell shape	GO:0008360	113	0.023
tissue death	GO:0016271	102	0.022
nucleosome organization	GO:0034728	59	0.022
proteolysis	GO:0006508	192	0.022
protein dna complex assembly	GO:0065004	63	0.022
cellular response to chemical stimulus	GO:0070887	199	0.022
positive regulation of rna metabolic process	GO:0051254	271	0.021
regulation of mitotic cell cycle	GO:0007346	190	0.021
negative regulation of response to stimulus	GO:0048585	258	0.020
regulation of meiosis	GO:0040020	3	0.020
mitotic nuclear division	GO:0007067	213	0.020
negative regulation of cellular component organization	GO:0051129	108	0.020
mating behavior	GO:0007617	106	0.019
multicellular organismal reproductive behavior	GO:0033057	110	0.019
protein transport	GO:0015031	155	0.019
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.019
dorsal ventral pattern formation	GO:0009953	133	0.019
positive regulation of immune system process	GO:0002684	68	0.019
negative regulation of cell cycle process	GO:0010948	109	0.019
posttranscriptional gene silencing	GO:0016441	46	0.019
imaginal disc derived appendage development	GO:0048737	399	0.018
negative regulation of transcription dna templated	GO:0045892	237	0.018
peptidyl lysine modification	GO:0018205	57	0.018
protein acylation	GO:0043543	42	0.018
salivary gland development	GO:0007431	162	0.018
regulation of anatomical structure size	GO:0090066	163	0.018
neuromuscular junction development	GO:0007528	149	0.018
developmental maturation	GO:0021700	172	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
morphogenesis of an epithelium	GO:0002009	276	0.017
neuron recognition	GO:0008038	101	0.017
vesicle mediated transport	GO:0016192	381	0.017
negative regulation of cell cycle	GO:0045786	116	0.017
cellular response to organic substance	GO:0071310	132	0.017
locomotory behavior	GO:0007626	176	0.016
chromosome organization	GO:0051276	360	0.016
salivary gland histolysis	GO:0035070	88	0.016
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.016
nephron morphogenesis	GO:0072028	3	0.016
positive regulation of developmental growth	GO:0048639	62	0.016
molting cycle process	GO:0022404	29	0.016
autophagic cell death	GO:0048102	83	0.016
negative regulation of gene expression epigenetic	GO:0045814	77	0.016
negative regulation of rna metabolic process	GO:0051253	251	0.016
response to oxygen containing compound	GO:1901700	200	0.016
gene silencing by mirna	GO:0035195	22	0.016
phagocytosis	GO:0006909	215	0.015
positive regulation of gene expression	GO:0010628	290	0.015
embryo development ending in birth or egg hatching	GO:0009792	152	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
positive regulation of growth	GO:0045927	75	0.014
endocytosis	GO:0006897	310	0.014
circadian behavior	GO:0048512	76	0.014
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.014
single organism nuclear import	GO:1902593	51	0.014
cellular response to sterol depletion	GO:0071501	3	0.014
regulation of phosphatase activity	GO:0010921	3	0.014
regulation of cell proliferation	GO:0042127	163	0.014
negative regulation of cellular biosynthetic process	GO:0031327	277	0.014
positive regulation of cellular component organization	GO:0051130	156	0.014
regulation of wnt signaling pathway	GO:0030111	68	0.014
positive regulation of developmental process	GO:0051094	143	0.014
extrinsic apoptotic signaling pathway	GO:0097191	1	0.013
gene silencing by rna	GO:0031047	57	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
regulation of chromatin modification	GO:1903308	28	0.013
cellular macromolecule localization	GO:0070727	220	0.013
intracellular signal transduction	GO:0035556	300	0.013
organic substance transport	GO:0071702	257	0.012
histone acetylation	GO:0016573	38	0.012
growth	GO:0040007	359	0.012
mating	GO:0007618	120	0.012
establishment of localization in cell	GO:0051649	402	0.012
gland development	GO:0048732	191	0.012
response to lipid	GO:0033993	38	0.012
cell cycle phase transition	GO:0044770	140	0.012
imaginal disc derived leg morphogenesis	GO:0007480	80	0.012
negative regulation of cellular metabolic process	GO:0031324	382	0.012
nuclear import	GO:0051170	51	0.012
regulation of cell differentiation	GO:0045595	302	0.012
response to nutrient levels	GO:0031667	114	0.012
ras protein signal transduction	GO:0007265	88	0.011
negative regulation of signaling	GO:0023057	219	0.011
nuclear transport	GO:0051169	72	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
establishment of protein localization	GO:0045184	163	0.011
sensory perception of chemical stimulus	GO:0007606	116	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.011
regulation of chromatin silencing	GO:0031935	36	0.011
chromatin silencing	GO:0006342	76	0.011
cellular response to dna damage stimulus	GO:0006974	223	0.011
response to bacterium	GO:0009617	198	0.011
regulation of protein metabolic process	GO:0051246	256	0.011
response to organic cyclic compound	GO:0014070	89	0.011
appendage development	GO:0048736	401	0.010
regulation of anatomical structure morphogenesis	GO:0022603	242	0.010
purine nucleoside biosynthetic process	GO:0042451	3	0.010
protein glycosylation	GO:0006486	32	0.010
regulation of chromatin organization	GO:1902275	32	0.010
immune system process	GO:0002376	347	0.010
adult behavior	GO:0030534	137	0.010
positive regulation of transcription dna templated	GO:0045893	266	0.010

uex disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.018
nervous system disease	DOID:863	0.017
disease of cellular proliferation	DOID:14566	0.017
central nervous system disease	DOID:331	0.011
cardiovascular system disease	DOID:1287	0.011
musculoskeletal system disease	DOID:17	0.011
muscular disease	DOID:0080000	0.011
muscle tissue disease	DOID:66	0.011
myopathy	DOID:423	0.011
heart disease	DOID:114	0.011
cardiomyopathy	DOID:0050700	0.011
intrinsic cardiomyopathy	DOID:0060036	0.011

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