Drosophila melanogaster

39 known processes

RpII215 (Dmel_CG1554)

RNA polymerase II 215kD subunit

(Aliases: RNA Pol II,dRPB1,RNAPII0,Pol IIo[ser2],Pol II0[ser5],CTD,Pol-IIa,RNA pol IIo,RpII,pol II,RNA pol II,l(1)DF912,RPB1,RNApolII,RNAP,RNAP II,POL,RNA polII,5,Ubl,CG1554,PolII,Pol IIo,RNAP II LS,l(1)10Ca,Pol IIa,l(1)DC912,II,Rpll215,L5,RNAPII,Pol II CTD,l(1)G0040,Pol IIo[ser5],polII,Rpb1,8WG16,H5,RNA PolII,Dmel\CG1554,RNA Pol II CTD,l(1)L5,Pol II0[ser2],PolIIo,Pol II)

RpII215 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of macromolecule metabolic processGO:00106044050.851
Human
protein targeting to nucleusGO:0044744510.849
negative regulation of cellular biosynthetic processGO:00313272770.795
negative regulation of nitrogen compound metabolic processGO:00511722650.646
response to oxygen containing compoundGO:19017002000.610
response to organic substanceGO:00100332840.607
immune responseGO:00069552460.563
positive regulation of rna biosynthetic processGO:19026802660.557
vesicle mediated transportGO:00161923810.528
cellular response to dna damage stimulusGO:00069742230.523
positive regulation of transcription dna templatedGO:00458932660.465
response to radiationGO:00093141550.457
negative regulation of nucleobase containing compound metabolic processGO:00459342610.456
intracellular protein transportGO:00068861040.442
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.438
response to other organismGO:00517072930.437
negative regulation of biosynthetic processGO:00098902770.414
transcription from rna polymerase ii promoterGO:00063663680.413
Human Yeast Worm
embryo development ending in birth or egg hatchingGO:00097921520.401
Worm
response to biotic stimulusGO:00096072940.400
regulation of protein metabolic processGO:00512462560.376
regulation of mrna 3 end processingGO:003144070.371
regulation of cellular protein metabolic processGO:00322682430.355
response to abiotic stimulusGO:00096283410.349
spermatogenesisGO:00072832000.338
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.336
larval developmentGO:00021641040.310
Worm
mitotic cell cycle phase transitionGO:00447721380.308
stem cell differentiationGO:00488631170.306
negative regulation of rna biosynthetic processGO:19026792400.303
nuclear transportGO:0051169720.299
mrna metabolic processGO:00160711240.294
regulation of phosphorus metabolic processGO:00511742100.292
positive regulation of cellular biosynthetic processGO:00313283160.278
negative regulation of nucleic acid templated transcriptionGO:19035072400.269
defense responseGO:00069523000.269
organelle assemblyGO:00709251980.254
regulation of dna templated transcription elongationGO:0032784170.246
positive regulation of biosynthetic processGO:00098913160.244
negative regulation of cellular metabolic processGO:00313243820.242
cellular macromolecule localizationGO:00707272200.218
nucleocytoplasmic transportGO:0006913720.218
regulation of phosphate metabolic processGO:00192202100.218
posttranscriptional regulation of gene expressionGO:00106081450.212
regulation of cell cycle phase transitionGO:19019871300.206
endocytosisGO:00068973100.204
negative regulation of rna metabolic processGO:00512532510.204
regionalizationGO:00030024160.201
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.200
mitotic spindle organizationGO:00070522200.193
Worm
muscle structure developmentGO:00610612240.190
organic substance transportGO:00717022570.183
establishment of localization in cellGO:00516494020.182
regulation of protein modification processGO:00313991120.178
spindle organizationGO:00070512530.176
Worm
regulation of transcription from rna polymerase ii promoterGO:00063573780.176
protein import into nucleusGO:0006606510.175
negative regulation of transcription dna templatedGO:00458922370.173
negative regulation of gene expressionGO:00106293870.170
regulation of gene expression epigeneticGO:00400291280.164
regulation of response to stressGO:00801342000.160
protein importGO:0017038550.159
positive regulation of cellular protein metabolic processGO:00322701180.159
male gamete generationGO:00482322010.158
response to external biotic stimulusGO:00432072930.157
positive regulation of protein metabolic processGO:00512471280.156
regulation of mrna metabolic processGO:1903311720.154
cell migrationGO:00164772380.151
positive regulation of nucleic acid templated transcriptionGO:19035082660.150
nucleoside triphosphate catabolic processGO:00091431080.143
small molecule metabolic processGO:00442813050.141
regulation of nucleocytoplasmic transportGO:0046822350.139
establishment of protein localization to organelleGO:0072594620.134
skin developmentGO:0043588650.134
stem cell developmentGO:0048864790.132
response to light stimulusGO:00094161240.131
regulation of transportGO:00510491810.131
neurological system processGO:00508773580.129
aromatic compound catabolic processGO:00194391660.129
rna splicingGO:0008380830.125
Human
regulation of mrna processingGO:0050684710.122
chromosome organizationGO:00512763600.122
appendage developmentGO:00487364010.122
cellular nitrogen compound catabolic processGO:00442701650.120
cellular response to chemical stimulusGO:00708871990.119
positive regulation of rna metabolic processGO:00512542710.119
Human
positive regulation of gene expressionGO:00106282900.117
Human
cellular protein localizationGO:00346131600.117
regulation of defense responseGO:00313471020.117
response to heatGO:0009408630.117
single organism intracellular transportGO:19025822070.116
cellular response to oxygen containing compoundGO:1901701790.116
female germ line cyst formationGO:0048135420.114
stem cell maintenanceGO:0019827670.110
positive regulation of nucleobase containing compound metabolic processGO:00459353320.108
Human
mrna transportGO:0051028150.108
dna templated transcription elongationGO:0006354180.107
nuclear importGO:0051170510.107
regulation of cellular ketone metabolic processGO:001056530.106
multi organism behaviorGO:00517051750.105
protein localizationGO:00081042840.104
axis specificationGO:00097981670.104
spermatid differentiationGO:00485151140.103
nuclear divisionGO:00002803320.101
Worm
ribonucleoprotein complex assemblyGO:0022618230.101
chromatin organizationGO:00063252070.100
response to bacteriumGO:00096171980.099
regulation of microtubule cytoskeleton organizationGO:0070507410.096
innate immune responseGO:00450871440.095
mitotic nuclear divisionGO:00070672130.095
Worm
cell maturationGO:00484691440.095
protein localization to organelleGO:0033365820.095
negative regulation of multicellular organismal processGO:00512411420.095
positive regulation of molecular functionGO:00440931360.094
protein complex assemblyGO:00064612000.094
biological adhesionGO:00226101380.093
germarium derived egg chamber formationGO:00072931010.093
regulation of cellular component biogenesisGO:00440872010.091
chromatin modificationGO:00165681470.090
growthGO:00400073590.089
mrna processingGO:00063971040.087
protein targetingGO:0006605640.085
protein localization to nucleusGO:0034504550.084
establishment of rna localizationGO:0051236470.083
ribonucleotide catabolic processGO:00092611090.083
regulation of intracellular protein transportGO:0033157460.083
response to organonitrogen compoundGO:0010243750.082
amine metabolic processGO:0009308120.081
ribonucleoprotein complex subunit organizationGO:0071826280.080
cell cell junction organizationGO:0045216550.079
defense response to other organismGO:00985422250.079
organophosphate metabolic processGO:00196371950.079
nucleobase containing compound catabolic processGO:00346551650.078
multicellular organismal reproductive behaviorGO:00330571100.077
negative regulation of protein metabolic processGO:0051248850.073
nucleobase containing small molecule metabolic processGO:00550861740.073
response to alcoholGO:0097305950.072
cytoplasmic transportGO:00164821300.072
single organism cellular localizationGO:19025801800.072
negative regulation of mitotic cell cycleGO:00459301090.071
rna processingGO:00063961470.071
Human
regulation of alternative mrna splicing via spliceosomeGO:0000381600.071
body morphogenesisGO:001017120.071
negative regulation of immune system processGO:0002683500.071
organelle localizationGO:00516401480.071
central nervous system developmentGO:00074172010.070
purine containing compound catabolic processGO:00725231120.070
single organism nuclear importGO:1902593510.070
heterocycle catabolic processGO:00467001660.069
cell proliferationGO:00082832990.069
regulation of localizationGO:00328792750.068
carbohydrate derivative catabolic processGO:19011361180.068
positive regulation of nitrogen compound metabolic processGO:00511733540.067
Human
rna localizationGO:00064031150.066
oocyte microtubule cytoskeleton polarizationGO:0008103220.065
organonitrogen compound catabolic processGO:19015651280.064
oocyte developmentGO:00485991240.063
imaginal disc derived appendage morphogenesisGO:00351143950.063
cell divisionGO:00513012480.063
Worm
organic cyclic compound catabolic processGO:19013611680.062
negative regulation of macromolecule biosynthetic processGO:00105582700.062
regulation of mitotic cell cycleGO:00073461900.061
adult behaviorGO:00305341370.061
positive regulation of macromolecule biosynthetic processGO:00105572830.059
dna repairGO:0006281540.056
Yeast
rna polyadenylationGO:0043631120.056
nitrogen compound transportGO:0071705850.056
histone modificationGO:00165701060.055
nucleoside catabolic processGO:00091641120.054
purine ribonucleotide catabolic processGO:00091541090.054
covalent chromatin modificationGO:00165691060.054
heart developmentGO:0007507820.054
regulation of organelle organizationGO:00330431960.053
regulation of cell differentiationGO:00455953020.053
photoreceptor cell differentiationGO:00465301700.053
nucleoside metabolic processGO:00091161270.053
regulation of cellular amino acid metabolic processGO:000652100.052
single organism behaviorGO:00447083910.051
intracellular transportGO:00469072280.051
transcription elongation from rna polymerase ii promoterGO:0006368180.051
purine nucleotide metabolic processGO:00061631460.051
chromatin remodelingGO:0006338720.050
regulation of intracellular transportGO:0032386640.050
peptidyl amino acid modificationGO:00181931050.049
purine nucleotide catabolic processGO:00061951090.049
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.049
macromolecular complex assemblyGO:00650032560.046
defense response to gram negative bacteriumGO:0050829940.045
pole plasm mrna localizationGO:0019094490.044
purine ribonucleoside triphosphate catabolic processGO:00092071080.044
positive regulation of response to stimulusGO:00485843230.044
response to nitrogen compoundGO:1901698900.043
response to endogenous stimulusGO:00097191190.043
regulation of transferase activityGO:0051338580.043
gliogenesisGO:0042063800.043
regulation of protein phosphorylationGO:0001932640.042
oocyte microtubule cytoskeleton organizationGO:0016325350.042
rna 3 end processingGO:0031123450.041
maintenance of locationGO:0051235730.041
cellular amino acid metabolic processGO:0006520610.041
regulation of protein import into nucleusGO:0042306280.041
epidermis developmentGO:0008544650.041
dna damage checkpointGO:0000077780.040
purine ribonucleoside metabolic processGO:00461281270.040
germarium derived female germ line cyst formationGO:0030727420.040
protein transportGO:00150311550.040
regulation of innate immune responseGO:0045088710.040
mrna 3 end processingGO:0031124280.040
positive regulation of intracellular transportGO:0032388420.039
positive regulation of cell proliferationGO:0008284470.038
segmentationGO:00352822070.038
cell cell signaling involved in cell fate commitmentGO:00451682100.038
positive regulation of nucleocytoplasmic transportGO:0046824240.037
purine nucleoside triphosphate metabolic processGO:00091441190.037
regulation of cytoplasmic transportGO:1903649470.037
wing disc morphogenesisGO:00074723440.036
cellular ketone metabolic processGO:0042180240.036
regulation of cellular localizationGO:00603411360.036
mitotic dna damage checkpointGO:0044773740.036
nucleotide metabolic processGO:00091171610.036
negative regulation of transcription factor import into nucleusGO:004299240.035
anterior posterior pattern specificationGO:00099521360.035
cell junction assemblyGO:0034329420.035
negative regulation of cellular protein metabolic processGO:0032269850.034
epidermal cell differentiationGO:0009913510.034
post embryonic appendage morphogenesisGO:00351203850.034
cellular amine metabolic processGO:0044106120.034
dendrite developmentGO:00163582040.034
positive regulation of catabolic processGO:00098961050.033
regulation of microtubule based processGO:0032886490.033
reproductive system developmentGO:0061458740.033
appendage morphogenesisGO:00351073970.032
positive regulation of cell motilityGO:200014730.032
defense response to bacteriumGO:00427421780.032
regulation of multi organism processGO:00439001310.032
establishment of protein localizationGO:00451841630.031
lipid localizationGO:0010876540.031
nuclear exportGO:0051168240.031
purine nucleoside catabolic processGO:00061521120.031
purine ribonucleotide metabolic processGO:00091501450.030
ribonucleotide metabolic processGO:00092591450.030
cellular response to abiotic stimulusGO:0071214580.030
myofibril assemblyGO:0030239360.030
organonitrogen compound metabolic processGO:19015643180.029
regulation of epidermal cell differentiationGO:004560430.029
regulation of molecular functionGO:00650092170.029
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.028
gonad developmentGO:0008406500.028
regulation of protein localization to nucleusGO:1900180290.028
regulation of immune system processGO:00026821760.028
dendrite morphogenesisGO:00488131990.027
positive regulation of defense responseGO:0031349590.027
phosphorylationGO:00163102940.027
dorsal ventral pattern formationGO:00099531330.027
positive regulation of developmental growthGO:0048639620.027
imaginal disc derived wing morphogenesisGO:00074763370.027
positive regulation of cellular component organizationGO:00511301560.027
axon guidanceGO:00074112330.027
carboxylic acid metabolic processGO:0019752920.026
nucleobase containing compound transportGO:0015931560.026
cellular protein complex assemblyGO:0043623710.025
negative regulation of phosphorus metabolic processGO:0010563450.025
lateral inhibitionGO:00463312060.025
cellular component assembly involved in morphogenesisGO:00109271510.025
telencephalon developmentGO:002153720.024
developmental growthGO:00485892800.024
g1 s transition of mitotic cell cycleGO:0000082310.024
regulation of catalytic activityGO:00507901850.024
protein complex disassemblyGO:0043241360.023
ribonucleoside triphosphate catabolic processGO:00092031080.023
nucleoside phosphate catabolic processGO:19012921100.023
agingGO:00075681430.023
establishment or maintenance of cytoskeleton polarityGO:0030952440.022
negative regulation of developmental processGO:00510932010.022
positive regulation of mitotic cell cycleGO:0045931340.022
response to lipopolysaccharideGO:003249640.022
hindbrain developmentGO:003090220.022
protein modification processGO:00362114380.022
Worm
purine nucleoside triphosphate catabolic processGO:00091461080.022
organic substance catabolic processGO:19015753080.022
actomyosin structure organizationGO:0031032560.021
regulation of phosphorylationGO:00423251470.021
axon developmentGO:00615642970.021
regulation of cellular amine metabolic processGO:003323830.021
axonogenesisGO:00074092900.021
regulation of nucleobase containing compound transportGO:003223940.020
nucleoside triphosphate metabolic processGO:00091411200.020
immune response activating signal transductionGO:000275720.020
ribonucleoside triphosphate metabolic processGO:00091991190.020
regulation of cytoskeleton organizationGO:0051493890.020
regulation of protein stabilityGO:0031647430.020
cell adhesionGO:00071551360.020
cellular macromolecular complex assemblyGO:00346221530.020
protein complex biogenesisGO:00702712010.020
regulation of protein polymerizationGO:0032271280.019
cognitionGO:00508901410.019
nitric oxide metabolic processGO:004620910.019
cell junction organizationGO:0034330570.019
sex differentiationGO:0007548810.019
positive regulation of signalingGO:00230562430.019
positive regulation of signal transductionGO:00099672230.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
regulation of embryonic pattern specificationGO:1902875270.018
positive regulation of cell cycleGO:0045787430.018
multicellular organismal agingGO:00102591400.018
localization of cellGO:00516742570.018
negative regulation of cell cycleGO:00457861160.018
response to woundingGO:0009611940.018
histone h3 acetylationGO:0043966110.017
chromatin silencingGO:0006342760.017
purine nucleoside metabolic processGO:00422781270.017
negative regulation of organelle organizationGO:0010639560.017
nucleic acid transportGO:0050657460.017
cell cycle g1 s phase transitionGO:0044843310.017
mrna polyadenylationGO:0006378110.017
regulation of multicellular organismal developmentGO:20000264140.017
prostaglandin biosynthetic processGO:000151610.017
organophosphate catabolic processGO:00464341120.017
oxoacid metabolic processGO:00434361030.017
intracellular signal transductionGO:00355563000.017
positive regulation of multicellular organismal processGO:00512401430.016
cellular response to organic substanceGO:00713101320.016
homeostatic processGO:00425921990.016
regulation of establishment of protein localizationGO:0070201610.016
negative regulation of cell communicationGO:00106482230.016
protein phosphorylationGO:00064681690.016
heart morphogenesisGO:0003007320.016
muscle organ developmentGO:00075171270.016
meiotic spindle organizationGO:0000212360.016
purine containing compound metabolic processGO:00725211550.016
positive regulation of phosphorylationGO:0042327870.016
positive regulation of immune responseGO:0050778630.015
regulation of cell deathGO:00109411730.015
regulation of pole plasm oskar mrna localizationGO:0007317270.015
purine ribonucleoside catabolic processGO:00461301120.015
histone methylationGO:0016571400.015
positive regulation of protein modification processGO:0031401580.015
lipid storageGO:0019915380.015
meiotic cell cycleGO:00513211710.015
embryonic development via the syncytial blastodermGO:00017001480.015
rna catabolic processGO:0006401370.014
carbohydrate derivative metabolic processGO:19011352170.014
multi multicellular organism processGO:00447061230.014
positive regulation of dna templated transcription elongationGO:0032786110.014
imaginal disc derived appendage developmentGO:00487373990.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.013
positive regulation of immune system processGO:0002684680.013
macromolecule methylationGO:0043414450.013
Worm
positive regulation of innate immune responseGO:0045089380.013
muscle cell developmentGO:0055001500.013
mrna splicing via spliceosomeGO:0000398730.013
oocyte differentiationGO:00099941450.013
germ line cyst formationGO:0048134440.013
regulation of protein localizationGO:0032880760.013
alternative mrna splicing via spliceosomeGO:0000380600.013
protein methylationGO:0006479430.013
Worm
regulation of notch signaling pathwayGO:00085931000.013
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.013
regulation of protein kinase activityGO:0045859510.013
gene silencingGO:00164581380.013
positive regulation of cellular catabolic processGO:0031331950.013
regulation of developmental growthGO:00486381740.013
translationGO:0006412690.012
regulation of hemocyte proliferationGO:0035206370.012
regulation of epithelial cell differentiationGO:003085640.012
glycosyl compound catabolic processGO:19016581120.012
cellular response to molecule of bacterial originGO:007121930.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
regulation of mrna splicing via spliceosomeGO:0048024640.012
defense response to virusGO:0051607230.012
blastoderm segmentationGO:00073501590.012
developmental maturationGO:00217001720.012
mitochondrial membrane organizationGO:000700630.012
circulatory system developmentGO:0072359820.012
cell cycle phase transitionGO:00447701400.012
deathGO:00162652840.012
positive regulation of intracellular protein transportGO:0090316300.012
positive regulation of protein phosphorylationGO:0001934340.012
regulation of immune responseGO:00507761180.012
response to organic cyclic compoundGO:0014070890.012
negative regulation of immune responseGO:0050777390.012
regulation of cell cycle processGO:00105641810.012
activation of innate immune responseGO:000221840.011
meiotic cell cycle processGO:19030461320.011
histone deubiquitinationGO:001657880.011
immune response regulating signaling pathwayGO:000276420.011
regulation of protein transportGO:0051223570.011
negative regulation of cell differentiationGO:00455961430.011
juvenile hormone mediated signaling pathwayGO:003562630.011
histone lysine methylationGO:0034968320.011
negative regulation of translationGO:0017148280.011
regulation of cell proliferationGO:00421271630.011
positive regulation of intracellular signal transductionGO:19025331160.011
positive regulation of cell communicationGO:00106472500.011
regulation of response to dna damage stimulusGO:2001020230.011
macromolecule catabolic processGO:00090571610.011
intracellular receptor signaling pathwayGO:0030522190.011
mapk cascadeGO:00001651070.011
chromatin mediated maintenance of transcriptionGO:004809670.011
response to hypoxiaGO:0001666530.011
cell deathGO:00082192790.011
cellular response to organonitrogen compoundGO:0071417360.011
imaginal disc derived wing vein morphogenesisGO:0008586440.010
positive regulation of developmental processGO:00510941430.010
positive regulation of phosphorus metabolic processGO:00105621390.010
posttranscriptional gene silencing by rnaGO:0035194450.010
male mating behaviorGO:0060179700.010
response to temperature stimulusGO:00092661060.010
regulation of hydrolase activityGO:0051336970.010
glycosyl compound metabolic processGO:19016571270.010

RpII215 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.058
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015