Drosophila melanogaster

65 known processes

fab1 (Dmel_CG6355)

CG6355 gene product from transcript CG6355-RA

(Aliases: fab-1,Fab1,PIKfyve,Dmel\CG6355,EG:52C10.5,CG6355)

fab1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000264140.290
negative regulation of organ growthGO:0046621150.247
single organism intracellular transportGO:19025822070.139
regulation of imaginal disc growthGO:0045570260.107
intracellular transportGO:00469072280.103
embryonic morphogenesisGO:00485982060.101
vesicle mediated transportGO:00161923810.097
imaginal disc growthGO:0007446370.095
negative regulation of nucleobase containing compound metabolic processGO:00459342610.094
tube developmentGO:00352952440.090
compound eye developmentGO:00487493070.089
eye morphogenesisGO:00485922600.086
catabolic processGO:00090564090.085
chromosome organizationGO:00512763600.081
regulation of growthGO:00400082330.081
organonitrogen compound metabolic processGO:19015643180.078
compound eye morphogenesisGO:00017452490.077
cell cycle phase transitionGO:00447701400.075
regulation of developmental growthGO:00486381740.074
axis specificationGO:00097981670.074
negative regulation of imaginal disc growthGO:004557180.065
regulation of proteolysisGO:0030162870.064
endosomal transportGO:0016197440.063
protein complex assemblyGO:00064612000.062
cellularizationGO:0007349900.061
negative regulation of rna metabolic processGO:00512532510.060
response to bacteriumGO:00096171980.060
response to organic substanceGO:00100332840.059
negative regulation of cell cycle processGO:00109481090.054
proteolysisGO:00065081920.053
tube morphogenesisGO:00352391910.053
eye developmentGO:00016543230.053
protein modification processGO:00362114380.053
cellular macromolecule localizationGO:00707272200.052
regulation of cell proliferationGO:00421271630.052
regulation of cell cycleGO:00517262910.051
tissue morphogenesisGO:00487292970.051
single organism membrane fusionGO:0044801420.051
cellular macromolecule catabolic processGO:00442651360.049
cellular protein modification processGO:00064644380.049
nucleoside triphosphate metabolic processGO:00091411200.049
small molecule metabolic processGO:00442813050.049
single organism catabolic processGO:00447122280.048
organic substance catabolic processGO:19015753080.048
regulation of apoptotic processGO:00429811300.047
mitotic cell cycle phase transitionGO:00447721380.046
negative regulation of signal transductionGO:00099682060.046
negative regulation of developmental growthGO:0048640640.044
regulation of cellular response to stressGO:0080135890.043
organelle fusionGO:0048284460.043
purine ribonucleoside triphosphate metabolic processGO:00092051190.043
purine containing compound metabolic processGO:00725211550.042
negative regulation of transcription dna templatedGO:00458922370.042
nuclear divisionGO:00002803320.042
regulation of intracellular signal transductionGO:19025312360.041
intracellular signal transductionGO:00355563000.041
regionalizationGO:00030024160.040
cell cell signaling involved in cell fate commitmentGO:00451682100.040
positive regulation of peptidase activityGO:0010952290.040
cell growthGO:00160491080.040
segmentationGO:00352822070.039
ribose phosphate metabolic processGO:00196931450.039
purine nucleoside triphosphate catabolic processGO:00091461080.039
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.039
purine nucleotide catabolic processGO:00061951090.039
cytoplasmic transportGO:00164821300.038
protein localizationGO:00081042840.038
spermatid developmentGO:0007286980.038
protein transportGO:00150311550.037
protein modification by small protein conjugation or removalGO:00706471060.037
purine containing compound catabolic processGO:00725231120.036
nucleoside phosphate metabolic processGO:00067531620.036
regulation of endopeptidase activityGO:0052548360.036
organophosphate metabolic processGO:00196371950.036
nucleoside phosphate catabolic processGO:19012921100.035
regulation of neural precursor cell proliferationGO:2000177350.035
endocytosisGO:00068973100.034
negative regulation of growthGO:0045926840.034
pigmentationGO:0043473750.034
nucleoside catabolic processGO:00091641120.034
negative regulation of cell cycleGO:00457861160.034
negative regulation of nitrogen compound metabolic processGO:00511722650.034
nucleotide catabolic processGO:00091661090.033
response to other organismGO:00517072930.033
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.033
purine nucleoside catabolic processGO:00061521120.033
purine nucleotide metabolic processGO:00061631460.033
cellular amino acid metabolic processGO:0006520610.032
spermatid differentiationGO:00485151140.032
establishment of protein localization to organelleGO:0072594620.032
organophosphate biosynthetic processGO:0090407460.032
organ growthGO:0035265560.031
nucleoside triphosphate catabolic processGO:00091431080.031
oxoacid metabolic processGO:00434361030.031
regulation of cysteine type endopeptidase activityGO:2000116270.030
defense response to bacteriumGO:00427421780.030
mitotic sister chromatid segregationGO:0000070870.030
lysosomal transportGO:0007041130.030
negative regulation of gene expression epigeneticGO:0045814770.030
regulation of mitotic cell cycleGO:00073461900.029
nucleotide metabolic processGO:00091171610.029
neurological system processGO:00508773580.029
forebrain developmentGO:003090020.029
cell proliferationGO:00082832990.029
ribonucleoside triphosphate catabolic processGO:00092031080.028
membrane fusionGO:0061025420.028
membrane organizationGO:00610241120.028
ribonucleoside catabolic processGO:00424541120.028
sister chromatid segregationGO:0000819920.028
digestive tract developmentGO:00485651490.027
eye photoreceptor cell differentiationGO:00017541450.027
body morphogenesisGO:001017120.027
establishment or maintenance of cell polarityGO:00071631670.026
carbohydrate derivative catabolic processGO:19011361180.026
positive regulation of response to stimulusGO:00485843230.026
regulation of gene expression epigeneticGO:00400291280.026
sensory organ morphogenesisGO:00905962600.026
chromatin silencingGO:0006342760.025
multicellular organismal agingGO:00102591400.025
protein processingGO:0016485680.025
purine nucleoside metabolic processGO:00422781270.025
response to oxygen containing compoundGO:19017002000.025
positive regulation of cysteine type endopeptidase activityGO:2001056240.025
mitotic cell cycle embryonicGO:0045448380.025
regulation of organ growthGO:0046620420.024
nucleoside metabolic processGO:00091161270.024
positive regulation of nitrogen compound metabolic processGO:00511733540.024
organic acid metabolic processGO:00060821030.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.024
developmental growthGO:00485892800.024
response to lipopolysaccharideGO:003249640.024
programmed cell deathGO:00125012570.023
establishment of localization in cellGO:00516494020.023
growthGO:00400073590.023
defense response to other organismGO:00985422250.023
purine ribonucleoside triphosphate catabolic processGO:00092071080.023
purine ribonucleotide metabolic processGO:00091501450.023
immune system processGO:00023763470.023
ribonucleotide catabolic processGO:00092611090.023
regulation of cell developmentGO:00602842150.023
regulation of hydrolase activityGO:0051336970.023
negative regulation of mitotic cell cycle phase transitionGO:19019911030.023
cell deathGO:00082192790.023
epithelial cell developmentGO:00020642740.022
olfactory behaviorGO:0042048970.022
protein maturationGO:0051604710.022
g protein coupled receptor signaling pathwayGO:00071861360.022
posttranscriptional regulation of gene expressionGO:00106081450.022
muscle structure developmentGO:00610612240.022
regulation of catabolic processGO:00098941700.022
determination of adult lifespanGO:00083401370.022
nucleobase containing small molecule metabolic processGO:00550861740.022
ribonucleotide metabolic processGO:00092591450.022
apoptotic processGO:00069151590.022
negative regulation of rna biosynthetic processGO:19026792400.022
establishment of protein localizationGO:00451841630.022
negative regulation of cellular biosynthetic processGO:00313272770.021
cellular catabolic processGO:00442483720.021
activation of cysteine type endopeptidase activityGO:0097202170.021
cellular response to biotic stimulusGO:007121640.021
regulation of mitotic sister chromatid segregationGO:0033047280.021
gastrulationGO:0007369700.021
regulation of response to external stimulusGO:00321011150.021
regulation of cell growthGO:0001558430.020
cellular protein localizationGO:00346131600.020
anterior posterior pattern specificationGO:00099521360.020
organophosphate catabolic processGO:00464341120.020
mitotic nuclear divisionGO:00070672130.020
response to biotic stimulusGO:00096072940.020
cellular response to lipopolysaccharideGO:007122230.020
larval developmentGO:00021641040.020
carbohydrate derivative metabolic processGO:19011352170.020
negative regulation of cellular metabolic processGO:00313243820.020
heterocycle catabolic processGO:00467001660.020
locomotory behaviorGO:00076261760.020
glycosyl compound metabolic processGO:19016571270.019
telencephalon developmentGO:002153720.019
cellular lipid metabolic processGO:0044255830.019
intracellular protein transportGO:00068861040.019
negative regulation of developmental processGO:00510932010.019
aromatic compound catabolic processGO:00194391660.019
cellular macromolecular complex assemblyGO:00346221530.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
organonitrogen compound catabolic processGO:19015651280.019
regulation of multi organism processGO:00439001310.019
organonitrogen compound biosynthetic processGO:19015661170.019
regulation of cell cycle phase transitionGO:19019871300.019
stem cell developmentGO:0048864790.019
cellular response to dna damage stimulusGO:00069742230.019
single organism cellular localizationGO:19025801800.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
regulation of protein metabolic processGO:00512462560.019
purine ribonucleoside catabolic processGO:00461301120.018
positive regulation of signal transductionGO:00099672230.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
embryonic pattern specificationGO:00098801740.018
spermatogenesisGO:00072832000.018
response to external biotic stimulusGO:00432072930.018
chromosome separationGO:0051304420.018
negative regulation of notch signaling pathwayGO:0045746410.018
chromosome segregationGO:00070591570.018
protein targetingGO:0006605640.018
positive regulation of gene expressionGO:00106282900.018
protein localization to organelleGO:0033365820.018
blastoderm segmentationGO:00073501590.018
epithelial cell differentiationGO:00308553220.018
photoreceptor cell differentiationGO:00465301700.017
carboxylic acid metabolic processGO:0019752920.017
macromolecular complex assemblyGO:00650032560.017
actin filament organizationGO:00070151260.017
embryonic axis specificationGO:00005781070.017
negative regulation of cell cycle phase transitionGO:19019881030.017
negative regulation of signalingGO:00230572190.017
morphogenesis of follicular epitheliumGO:0016333360.017
morphogenesis of a polarized epitheliumGO:0001738930.017
endosome transport via multivesicular body sorting pathwayGO:0032509120.017
defense response to gram negative bacteriumGO:0050829940.017
negative regulation of gene expressionGO:00106293870.017
purine ribonucleoside metabolic processGO:00461281270.016
branching morphogenesis of an epithelial tubeGO:0048754450.016
phosphorylationGO:00163102940.016
regulation of cellular component biogenesisGO:00440872010.016
regulation of phosphate metabolic processGO:00192202100.016
negative regulation of cell deathGO:0060548810.016
negative regulation of response to stimulusGO:00485852580.016
positive regulation of biosynthetic processGO:00098913160.016
multi organism behaviorGO:00517051750.016
regulation of programmed cell deathGO:00430671520.016
cellular nitrogen compound catabolic processGO:00442701650.016
organelle assemblyGO:00709251980.016
digestive system developmentGO:00551231490.016
developmental pigmentationGO:0048066680.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
regulation of phosphorus metabolic processGO:00511742100.016
negative regulation of cell communicationGO:00106482230.016
positive regulation of catalytic activityGO:00430851180.016
nuclear body organizationGO:003057560.015
pigment metabolic processGO:0042440840.015
negative regulation of molecular functionGO:0044092510.015
organic cyclic compound catabolic processGO:19013611680.015
phagocytosisGO:00069092150.015
retina development in camera type eyeGO:006004140.015
response to organic cyclic compoundGO:0014070890.015
negative regulation of biosynthetic processGO:00098902770.015
response to abiotic stimulusGO:00096283410.015
regulation of catalytic activityGO:00507901850.015
peptidyl proline modificationGO:001820830.015
retina morphogenesis in camera type eyeGO:006004220.015
lateral inhibitionGO:00463312060.015
regulation of molecular functionGO:00650092170.015
mitotic spindle organizationGO:00070522200.015
positive regulation of phosphate metabolic processGO:00459371390.014
regulation of response to stressGO:00801342000.014
multi organism reproductive behaviorGO:00447051210.014
covalent chromatin modificationGO:00165691060.014
regulation of cell deathGO:00109411730.014
regulation of mitosisGO:0007088560.014
protein complex biogenesisGO:00702712010.014
establishment of vesicle localizationGO:0051650510.014
detection of stimulusGO:00516061560.014
gtp metabolic processGO:0046039720.014
regulation of transcription from rna polymerase ii promoterGO:00063573780.014
ribonucleoside metabolic processGO:00091191270.014
compound eye photoreceptor cell differentiationGO:00017511400.014
protein importGO:0017038550.014
spindle organizationGO:00070512530.014
negative regulation of multicellular organismal processGO:00512411420.014
positive regulation of cell communicationGO:00106472500.014
peptide metabolic processGO:0006518800.014
localization of cellGO:00516742570.014
regulation of intracellular protein transportGO:0033157460.014
positive regulation of intracellular signal transductionGO:19025331160.014
response to endoplasmic reticulum stressGO:0034976280.014
male gamete generationGO:00482322010.014
regulation of peptidase activityGO:0052547390.013
positive regulation of cellular protein metabolic processGO:00322701180.013
cellular component assembly involved in morphogenesisGO:00109271510.013
notch signaling pathwayGO:00072191200.013
camera type eye developmentGO:004301040.013
positive regulation of cellular biosynthetic processGO:00313283160.013
stem cell proliferationGO:0072089880.013
nucleoside monophosphate metabolic processGO:0009123520.013
jak stat cascadeGO:0007259490.013
signal transduction by phosphorylationGO:00230141070.013
chaeta developmentGO:0022416970.013
cellular response to organic cyclic compoundGO:0071407320.013
metaphase anaphase transition of cell cycleGO:0044784280.013
regulation of reproductive processGO:2000241540.013
nucleobase containing compound catabolic processGO:00346551650.013
single organism behaviorGO:00447083910.013
cellular response to organic substanceGO:00713101320.013
single organism biosynthetic processGO:00447112060.013
negative regulation of epithelial cell proliferationGO:005068040.013
organic substance transportGO:00717022570.013
endosome to lysosome transportGO:000833370.013
atp metabolic processGO:0046034490.013
glycosyl compound catabolic processGO:19016581120.013
wing disc morphogenesisGO:00074723440.012
homeostatic processGO:00425921990.012
maintenance of locationGO:0051235730.012
negative regulation of mitotic cell cycleGO:00459301090.012
secretionGO:00469031090.012
response to sterolGO:0036314340.012
cellular amide metabolic processGO:0043603800.012
mesenchymal cell differentiationGO:004876210.012
regulation of epithelial cell differentiationGO:003085640.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
regulation of synapse organizationGO:00508071100.012
dna metabolic processGO:00062592270.012
stem cell maintenanceGO:0019827670.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
single organism membrane organizationGO:0044802930.012
positive regulation of phosphorus metabolic processGO:00105621390.011
protein catabolic processGO:00301631010.011
mesoderm developmentGO:0007498780.011
dorsal ventral pattern formation imaginal discGO:0007450510.011
regulation of localizationGO:00328792750.011
compound eye photoreceptor developmentGO:0042051780.011
sex differentiationGO:0007548810.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
cellular response to chemical stimulusGO:00708871990.011
negative regulation of catalytic activityGO:0043086420.011
regulation of protein complex assemblyGO:0043254420.011
dorsal ventral pattern formationGO:00099531330.011
regulation of organelle organizationGO:00330431960.011
dephosphorylationGO:0016311510.011
regulation of metaphase anaphase transition of cell cycleGO:1902099260.011
synaptic vesicle localizationGO:0097479530.011
deathGO:00162652840.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
cellular response to external stimulusGO:0071496660.011
positive regulation of phosphorylationGO:0042327870.011
response to starvationGO:0042594970.011
regulation of ras protein signal transductionGO:0046578930.011
mesenchymal cell developmentGO:001403110.011
regulation of embryonic developmentGO:0045995680.011
rhythmic behaviorGO:0007622760.010
regulation of sister chromatid segregationGO:0033045280.010
nephron tubule developmentGO:007208030.010
mitotic cell cycle checkpointGO:0007093880.010
nephron epithelium developmentGO:007200930.010
mitotic sister chromatid separationGO:0051306300.010
regulation of cell cycle processGO:00105641810.010
cellular response to molecule of bacterial originGO:007121930.010
protein modification by small protein conjugationGO:0032446790.010
eye pigmentationGO:0048069430.010
molting cycle chitin based cuticleGO:0007591560.010
negative regulation of apoptotic processGO:0043066630.010
rna processingGO:00063961470.010
positive regulation of protein metabolic processGO:00512471280.010
organelle fissionGO:00482853400.010
kidney epithelium developmentGO:007207330.010
regulation of cellular protein metabolic processGO:00322682430.010
negative regulation of intracellular signal transductionGO:1902532570.010
response to extracellular stimulusGO:00099911160.010
ameboidal type cell migrationGO:00016671510.010

fab1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
disease of cellular proliferationDOID:1456600.021
disease of metabolismDOID:001466700.019
organ system cancerDOID:005068600.018
cancerDOID:16200.018