Drosophila melanogaster

183 known processes

RhoGEF4 (Dmel_CG8606)

CG8606 gene product from transcript CG8606-RA

(Aliases: CG8606,DRhoGEF4,Dmel\CG8606)

RhoGEF4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.186
small molecule metabolic processGO:00442813050.156
regulation of intracellular signal transductionGO:19025312360.151
purine ribonucleoside metabolic processGO:00461281270.148
organonitrogen compound metabolic processGO:19015643180.120
regulation of cell cycle processGO:00105641810.117
organelle fissionGO:00482853400.098
intracellular signal transductionGO:00355563000.091
negative regulation of nucleobase containing compound metabolic processGO:00459342610.090
heterocycle catabolic processGO:00467001660.087
purine ribonucleoside triphosphate metabolic processGO:00092051190.082
spindle organizationGO:00070512530.081
regulation of gene expression epigeneticGO:00400291280.081
mitotic cytokinesisGO:0000281500.077
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.074
organic acid metabolic processGO:00060821030.074
mitotic nuclear divisionGO:00070672130.073
organophosphate metabolic processGO:00196371950.069
cytoskeleton dependent cytokinesisGO:0061640810.068
purine nucleotide metabolic processGO:00061631460.067
single organism catabolic processGO:00447122280.066
ribonucleotide metabolic processGO:00092591450.064
mitotic spindle organizationGO:00070522200.063
organic cyclic compound catabolic processGO:19013611680.061
negative regulation of gene expressionGO:00106293870.059
negative regulation of signalingGO:00230572190.059
positive regulation of response to stimulusGO:00485843230.057
nucleoside metabolic processGO:00091161270.056
negative regulation of macromolecule biosynthetic processGO:00105582700.055
response to abiotic stimulusGO:00096283410.055
chromosome segregationGO:00070591570.054
establishment of localization in cellGO:00516494020.053
regulation of phosphorus metabolic processGO:00511742100.052
nucleoside phosphate metabolic processGO:00067531620.051
cell divisionGO:00513012480.049
negative regulation of nitrogen compound metabolic processGO:00511722650.049
glycosyl compound catabolic processGO:19016581120.049
negative regulation of biosynthetic processGO:00098902770.048
ribonucleoside metabolic processGO:00091191270.048
cellular nitrogen compound catabolic processGO:00442701650.048
organic substance catabolic processGO:19015753080.046
regulation of cell cycleGO:00517262910.045
regulation of programmed cell deathGO:00430671520.045
negative regulation of transcription dna templatedGO:00458922370.044
nucleoside catabolic processGO:00091641120.044
cytokinesisGO:0000910900.044
regulation of phosphorylationGO:00423251470.043
single organism behaviorGO:00447083910.043
regulation of phosphate metabolic processGO:00192202100.043
negative regulation of cellular biosynthetic processGO:00313272770.042
purine ribonucleotide metabolic processGO:00091501450.042
body morphogenesisGO:001017120.041
regulation of mitotic cell cycleGO:00073461900.040
cell deathGO:00082192790.040
nucleotide metabolic processGO:00091171610.040
phosphorylationGO:00163102940.039
response to organic substanceGO:00100332840.039
positive regulation of signal transductionGO:00099672230.038
nucleobase containing compound catabolic processGO:00346551650.038
organonitrogen compound catabolic processGO:19015651280.037
purine containing compound metabolic processGO:00725211550.037
nucleotide catabolic processGO:00091661090.037
purine nucleoside triphosphate catabolic processGO:00091461080.036
ribonucleoside triphosphate catabolic processGO:00092031080.036
sister chromatid segregationGO:0000819920.035
imaginal disc derived appendage developmentGO:00487373990.035
nuclear divisionGO:00002803320.034
regionalizationGO:00030024160.034
organic substance transportGO:00717022570.034
regulation of nervous system developmentGO:00519602480.034
carbohydrate derivative metabolic processGO:19011352170.034
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
meiosis iGO:0007127590.032
ras protein signal transductionGO:0007265880.032
compound eye developmentGO:00487493070.032
glycosyl compound metabolic processGO:19016571270.032
mitotic cell cycle phase transitionGO:00447721380.032
purine nucleotide catabolic processGO:00061951090.032
regulation of catabolic processGO:00098941700.032
purine containing compound catabolic processGO:00725231120.032
axonogenesisGO:00074092900.031
positive regulation of cell communicationGO:00106472500.031
regulation of molecular functionGO:00650092170.031
positive regulation of phosphate metabolic processGO:00459371390.030
regulation of response to stressGO:00801342000.030
immune system processGO:00023763470.030
post embryonic appendage morphogenesisGO:00351203850.030
negative regulation of cell cycle processGO:00109481090.030
purine nucleoside triphosphate metabolic processGO:00091441190.030
signal transduction by phosphorylationGO:00230141070.030
negative regulation of rna metabolic processGO:00512532510.029
regulation of mapk cascadeGO:0043408920.029
mitotic sister chromatid separationGO:0051306300.029
nucleobase containing small molecule metabolic processGO:00550861740.028
regulation of multicellular organismal developmentGO:20000264140.028
regulation of cellular protein metabolic processGO:00322682430.028
purine nucleoside metabolic processGO:00422781270.028
enzyme linked receptor protein signaling pathwayGO:00071671790.027
positive regulation of phosphorus metabolic processGO:00105621390.027
cellular catabolic processGO:00442483720.027
ribose phosphate metabolic processGO:00196931450.026
chromosome separationGO:0051304420.026
negative regulation of cell communicationGO:00106482230.026
regulation of proteolysisGO:0030162870.026
deathGO:00162652840.026
catabolic processGO:00090564090.026
regulation of cytoskeleton organizationGO:0051493890.026
negative regulation of cell deathGO:0060548810.026
eye morphogenesisGO:00485922600.025
purine nucleoside catabolic processGO:00061521120.025
ribonucleotide catabolic processGO:00092611090.025
negative regulation of cellular metabolic processGO:00313243820.025
regulation of neurogenesisGO:00507671580.025
response to oxygen containing compoundGO:19017002000.024
positive regulation of molecular functionGO:00440931360.024
cytoplasmic transportGO:00164821300.024
camera type eye developmentGO:004301040.024
dna repairGO:0006281540.023
positive regulation of signalingGO:00230562430.023
purine ribonucleoside monophosphate metabolic processGO:0009167500.023
small gtpase mediated signal transductionGO:0007264880.023
organophosphate catabolic processGO:00464341120.023
transcription from rna polymerase ii promoterGO:00063663680.023
regulation of protein metabolic processGO:00512462560.022
mitotic sister chromatid segregationGO:0000070870.022
purine ribonucleotide catabolic processGO:00091541090.022
protein complex biogenesisGO:00702712010.022
oxoacid metabolic processGO:00434361030.022
positive regulation of gene expressionGO:00106282900.022
positive regulation of macromolecule metabolic processGO:00106044050.021
regulation of cell differentiationGO:00455953020.021
chromatin organizationGO:00063252070.021
meiotic dna double strand break formationGO:004213810.021
aromatic compound catabolic processGO:00194391660.021
regulation of apoptotic processGO:00429811300.021
single organism biosynthetic processGO:00447112060.020
centrosome cycleGO:00070981370.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
negative regulation of signal transductionGO:00099682060.020
carboxylic acid metabolic processGO:0019752920.020
nucleoside triphosphate catabolic processGO:00091431080.020
nucleoside phosphate catabolic processGO:19012921100.020
cell proliferationGO:00082832990.020
positive regulation of phosphorylationGO:0042327870.020
ribonucleoside catabolic processGO:00424541120.020
establishment or maintenance of cell polarityGO:00071631670.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
eye developmentGO:00016543230.019
cellularizationGO:0007349900.019
photoreceptor cell differentiationGO:00465301700.019
intracellular transportGO:00469072280.019
regulation of catalytic activityGO:00507901850.018
embryonic heart tube developmentGO:0035050220.018
negative regulation of response to stimulusGO:00485852580.018
regulation of ras protein signal transductionGO:0046578930.018
establishment of spindle orientationGO:0051294180.018
negative regulation of cellular component organizationGO:00511291080.018
cellular response to biotic stimulusGO:007121640.018
dna packagingGO:0006323910.018
negative regulation of mitotic cell cycleGO:00459301090.017
response to temperature stimulusGO:00092661060.017
cell cycle phase transitionGO:00447701400.017
negative regulation of programmed cell deathGO:0043069720.017
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.017
regulation of cellular response to stressGO:0080135890.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
regulation of mitotic cell cycle phase transitionGO:19019901300.017
appendage morphogenesisGO:00351073970.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
developmental growthGO:00485892800.017
regulation of cell developmentGO:00602842150.016
peptidyl amino acid modificationGO:00181931050.016
regulation of protein modification processGO:00313991120.016
cellular protein complex disassemblyGO:0043624350.016
actin cytoskeleton organizationGO:00300362060.016
imaginal disc pattern formationGO:0007447910.016
female meiotic divisionGO:0007143700.016
cellular protein modification processGO:00064644380.016
purine nucleoside monophosphate metabolic processGO:0009126500.016
ribonucleoside monophosphate metabolic processGO:0009161510.016
negative regulation of cell cycle phase transitionGO:19019881030.016
embryo development ending in birth or egg hatchingGO:00097921520.016
chromatin modificationGO:00165681470.015
compound eye morphogenesisGO:00017452490.015
regulation of cell cycle phase transitionGO:19019871300.015
sensory organ morphogenesisGO:00905962600.015
ribonucleoside triphosphate metabolic processGO:00091991190.015
single organism intracellular transportGO:19025822070.015
regulation of cell divisionGO:0051302720.015
mitotic chromosome condensationGO:0007076220.015
apoptotic processGO:00069151590.015
regulation of cell deathGO:00109411730.015
carbohydrate derivative catabolic processGO:19011361180.014
endocytosisGO:00068973100.014
regulation of transferase activityGO:0051338580.014
negative regulation of organelle organizationGO:0010639560.014
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.014
dorsal ventral pattern formationGO:00099531330.014
cellular macromolecule localizationGO:00707272200.014
protein maturationGO:0051604710.014
regulation of mitosisGO:0007088560.014
imaginal disc derived appendage morphogenesisGO:00351143950.014
embryonic morphogenesisGO:00485982060.014
cellular response to dna damage stimulusGO:00069742230.013
lateral inhibitionGO:00463312060.013
phagocytosisGO:00069092150.013
spindle assembly involved in mitosisGO:0090307500.013
leg disc developmentGO:0035218920.013
spindle assemblyGO:0051225800.013
stem cell differentiationGO:00488631170.013
atp metabolic processGO:0046034490.013
cellular protein localizationGO:00346131600.013
camera type eye morphogenesisGO:004859320.013
negative regulation of rna biosynthetic processGO:19026792400.013
macromolecular complex assemblyGO:00650032560.013
mapk cascadeGO:00001651070.013
response to lipopolysaccharideGO:003249640.013
cellular component assembly involved in morphogenesisGO:00109271510.013
protein phosphorylationGO:00064681690.013
regulation of cellular amine metabolic processGO:003323830.012
regulation of cellular amino acid metabolic processGO:000652100.012
negative regulation of gene expression epigeneticGO:0045814770.012
cellular amino acid metabolic processGO:0006520610.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
cellular ketone metabolic processGO:0042180240.012
response to heatGO:0009408630.012
metaphase anaphase transition of cell cycleGO:0044784280.012
protein localizationGO:00081042840.012
meiotic nuclear divisionGO:00071261510.012
positive regulation of transferase activityGO:0051347260.012
purine ribonucleoside catabolic processGO:00461301120.012
amine metabolic processGO:0009308120.012
regulation of mitotic sister chromatid segregationGO:0033047280.012
protein modification processGO:00362114380.012
protein transportGO:00150311550.012
positive regulation of catalytic activityGO:00430851180.012
regulation of response to dna damage stimulusGO:2001020230.011
dna metabolic processGO:00062592270.011
positive regulation of hydrolase activityGO:0051345780.011
positive regulation of intracellular signal transductionGO:19025331160.011
negative regulation of chromosome segregationGO:0051985140.011
nucleoside triphosphate metabolic processGO:00091411200.011
ubiquitin dependent protein catabolic processGO:0006511780.011
nuclear dna replicationGO:003326010.011
single organism cellular localizationGO:19025801800.011
ribonucleoside monophosphate catabolic processGO:0009158390.011
cellular response to chemical stimulusGO:00708871990.011
negative regulation of cell cycleGO:00457861160.011
compound eye photoreceptor cell differentiationGO:00017511400.011
neurological system processGO:00508773580.011
positive regulation of ras protein signal transductionGO:0046579430.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
response to extracellular stimulusGO:00099911160.011
regulation of cellular ketone metabolic processGO:001056530.011
negative regulation of proteasomal protein catabolic processGO:1901799160.011
centrosome organizationGO:00512971630.011
meiotic cell cycle processGO:19030461320.011
microtubule based movementGO:0007018510.011
growthGO:00400073590.011
g1 s transition of mitotic cell cycleGO:0000082310.011
negative regulation of apoptotic processGO:0043066630.011
response to radiationGO:00093141550.010
adult behaviorGO:00305341370.010
negative regulation of cellular protein metabolic processGO:0032269850.010
positive regulation of nitrogen compound metabolic processGO:00511733540.010
response to biotic stimulusGO:00096072940.010
eye photoreceptor cell differentiationGO:00017541450.010
cell cycle g1 s phase transitionGO:0044843310.010
skeletal muscle fiber developmentGO:004874130.010
protein processingGO:0016485680.010
epithelial tube morphogenesisGO:0060562880.010
mitotic cell cycle checkpointGO:0007093880.010
pharynx developmentGO:006046510.010

RhoGEF4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
disease of cellular proliferationDOID:1456600.012