Drosophila melanogaster

45 known processes

gukh (Dmel_CG31043)

GUK-holder

(Aliases: Gukh,CG6003,GUKH,GUKh,CG14288,GukH,Dmel\CG31043,CG5456,anon-WO0118547.205,CG14287,CG31043)

gukh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonogenesisGO:00074092900.256
neuron projection guidanceGO:00974852410.222
axon guidanceGO:00074112330.202
chemotaxisGO:00069352490.195
axon developmentGO:00615642970.171
cellular protein modification processGO:00064644380.130
actin filament based processGO:00300292200.106
chromatin organizationGO:00063252070.102
synapse organizationGO:00508081960.095
taxisGO:00423303040.091
response to abiotic stimulusGO:00096283410.089
imaginal disc derived appendage morphogenesisGO:00351143950.089
positive regulation of transcription dna templatedGO:00458932660.088
protein ubiquitinationGO:0016567700.079
positive regulation of gene expressionGO:00106282900.077
cellular response to dna damage stimulusGO:00069742230.072
regionalizationGO:00030024160.070
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.069
protein modification by small protein conjugationGO:0032446790.063
lateral inhibitionGO:00463312060.062
positive regulation of cellular biosynthetic processGO:00313283160.061
protein modification processGO:00362114380.061
post embryonic appendage morphogenesisGO:00351203850.060
negative regulation of gene expressionGO:00106293870.059
dna conformation changeGO:00711031050.058
peptidyl lysine acetylationGO:0018394390.056
phosphorylationGO:00163102940.056
macromolecule catabolic processGO:00090571610.055
positive regulation of rna metabolic processGO:00512542710.055
camera type eye developmentGO:004301040.054
regulation of synaptic transmissionGO:0050804690.054
protein modification by small protein conjugation or removalGO:00706471060.053
single organism behaviorGO:00447083910.051
positive regulation of signal transductionGO:00099672230.049
positive regulation of rna biosynthetic processGO:19026802660.048
response to radiationGO:00093141550.048
positive regulation of macromolecule metabolic processGO:00106044050.048
morphogenesis of an epitheliumGO:00020092760.047
modification dependent macromolecule catabolic processGO:0043632790.047
dna metabolic processGO:00062592270.046
ras protein signal transductionGO:0007265880.045
negative regulation of cellular metabolic processGO:00313243820.045
posttranscriptional regulation of gene expressionGO:00106081450.044
retina development in camera type eyeGO:006004140.043
wing disc morphogenesisGO:00074723440.043
appendage morphogenesisGO:00351073970.043
eye developmentGO:00016543230.042
growthGO:00400073590.042
positive regulation of response to stimulusGO:00485843230.042
small molecule metabolic processGO:00442813050.040
regulation of cell cycle phase transitionGO:19019871300.040
epithelial cell developmentGO:00020642740.039
adult behaviorGO:00305341370.039
establishment or maintenance of cell polarityGO:00071631670.039
positive regulation of macromolecule biosynthetic processGO:00105572830.039
epithelial cell differentiationGO:00308553220.039
appendage developmentGO:00487364010.038
regulation of phosphate metabolic processGO:00192202100.037
intracellular signal transductionGO:00355563000.037
tissue morphogenesisGO:00487292970.037
protein phosphorylationGO:00064681690.036
nucleobase containing compound catabolic processGO:00346551650.036
imaginal disc derived appendage developmentGO:00487373990.036
nuclear divisionGO:00002803320.036
cellular catabolic processGO:00442483720.036
negative regulation of macromolecule biosynthetic processGO:00105582700.036
regulation of phosphorylationGO:00423251470.035
chromosome organizationGO:00512763600.034
negative regulation of developmental processGO:00510932010.034
reproductive behaviorGO:00190981220.034
cell proliferationGO:00082832990.034
negative regulation of cellular biosynthetic processGO:00313272770.034
antimicrobial humoral responseGO:0019730990.033
agingGO:00075681430.033
imaginal disc derived wing morphogenesisGO:00074763370.033
wnt signaling pathwayGO:0016055980.033
photoreceptor cell axon guidanceGO:0072499230.033
dendrite morphogenesisGO:00488131990.033
positive regulation of nitrogen compound metabolic processGO:00511733540.033
immune system processGO:00023763470.032
regulation of molecular functionGO:00650092170.032
intracellular transportGO:00469072280.032
positive regulation of nucleobase containing compound metabolic processGO:00459353320.032
positive regulation of cell communicationGO:00106472500.032
olfactory behaviorGO:0042048970.032
regulation of mitotic cell cycleGO:00073461900.031
positive regulation of biosynthetic processGO:00098913160.031
blastoderm segmentationGO:00073501590.031
regulation of developmental growthGO:00486381740.031
sensory organ morphogenesisGO:00905962600.031
positive regulation of nucleic acid templated transcriptionGO:19035082660.031
male gamete generationGO:00482322010.031
developmental growth involved in morphogenesisGO:0060560650.030
catabolic processGO:00090564090.030
regulation of protein metabolic processGO:00512462560.030
carbohydrate derivative metabolic processGO:19011352170.030
programmed cell deathGO:00125012570.029
ovarian follicle cell developmentGO:00307072480.029
cell motilityGO:00488702510.029
regulation of cellular amino acid metabolic processGO:000652100.029
single organism cellular localizationGO:19025801800.029
embryonic pattern specificationGO:00098801740.028
regulation of cellular protein metabolic processGO:00322682430.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
body morphogenesisGO:001017120.028
modification dependent protein catabolic processGO:0019941780.028
synaptic growth at neuromuscular junctionGO:00511241190.028
mitotic cell cycle phase transitionGO:00447721380.028
spermatid differentiationGO:00485151140.028
cellular protein catabolic processGO:0044257830.028
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
positive regulation of phosphorus metabolic processGO:00105621390.027
courtship behaviorGO:0007619680.027
regulation of nervous system developmentGO:00519602480.027
developmental maturationGO:00217001720.027
rhythmic behaviorGO:0007622760.027
organonitrogen compound metabolic processGO:19015643180.026
segmentationGO:00352822070.026
histone acetylationGO:0016573380.026
rna localizationGO:00064031150.026
photoreceptor cell differentiationGO:00465301700.026
eye photoreceptor cell differentiationGO:00017541450.026
developmental growthGO:00485892800.025
regulation of localizationGO:00328792750.025
establishment of organelle localizationGO:00516561220.025
positive regulation of signalingGO:00230562430.025
phagocytosisGO:00069092150.024
chemosensory behaviorGO:00076351060.024
ameboidal type cell migrationGO:00016671510.024
microtubule organizing center organizationGO:00310231680.024
negative regulation of nucleic acid templated transcriptionGO:19035072400.024
regulation of synapse structure and activityGO:00508031280.024
regulation of cellular component sizeGO:0032535980.023
extrinsic apoptotic signaling pathwayGO:009719110.023
camera type eye morphogenesisGO:004859320.023
cellular nitrogen compound catabolic processGO:00442701650.023
regulation of cell cycleGO:00517262910.023
establishment of localization in cellGO:00516494020.023
synapse assemblyGO:00074161430.023
regulation of transportGO:00510491810.023
localization of cellGO:00516742570.022
response to woundingGO:0009611940.022
negative regulation of rna biosynthetic processGO:19026792400.022
forebrain developmentGO:003090020.022
photoreceptor cell developmentGO:0042461960.022
regulation of cell differentiationGO:00455953020.022
regulation of vesicle mediated transportGO:0060627590.022
anatomical structure homeostasisGO:0060249970.021
chromatin modificationGO:00165681470.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
response to nutrient levelsGO:00316671140.021
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
sensory perception of chemical stimulusGO:00076061160.020
regulation of response to stressGO:00801342000.020
regulation of cellular component biogenesisGO:00440872010.020
regulation of protein ubiquitinationGO:0031396220.020
regulation of phosphorus metabolic processGO:00511742100.020
dephosphorylationGO:0016311510.020
regulation of intracellular signal transductionGO:19025312360.020
detection of stimulusGO:00516061560.020
dendrite developmentGO:00163582040.019
organic cyclic compound catabolic processGO:19013611680.019
regulation of notch signaling pathwayGO:00085931000.019
stem cell developmentGO:0048864790.019
larval developmentGO:00021641040.019
carbohydrate derivative biosynthetic processGO:1901137850.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
single organism intracellular transportGO:19025822070.019
homeostatic processGO:00425921990.019
regulation of small gtpase mediated signal transductionGO:0051056930.019
organic substance transportGO:00717022570.019
columnar cuboidal epithelial cell developmentGO:00020662490.019
cell divisionGO:00513012480.019
single organism biosynthetic processGO:00447112060.019
regulation of anatomical structure sizeGO:00900661630.019
response to mechanical stimulusGO:0009612280.018
multicellular organismal reproductive behaviorGO:00330571100.018
intracellular mrna localizationGO:0008298660.018
regulation of cell deathGO:00109411730.018
establishment of spindle localizationGO:0051293220.018
centrosome organizationGO:00512971630.018
regulation of ras protein signal transductionGO:0046578930.018
nucleoside phosphate metabolic processGO:00067531620.018
jnk cascadeGO:0007254500.018
male courtship behaviorGO:0008049630.018
regulation of anatomical structure morphogenesisGO:00226032420.018
purine nucleoside triphosphate catabolic processGO:00091461080.018
actin mediated cell contractionGO:0070252210.018
regulation of catalytic activityGO:00507901850.018
regulation of protein localizationGO:0032880760.018
eye morphogenesisGO:00485922600.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
vesicle mediated transportGO:00161923810.018
negative regulation of signalingGO:00230572190.018
negative regulation of mitotic cell cycle phase transitionGO:19019911030.018
respiratory system developmentGO:00605412130.018
receptor clusteringGO:004311330.018
meiotic cell cycleGO:00513211710.018
establishment of vesicle localizationGO:0051650510.018
internal peptidyl lysine acetylationGO:0018393380.018
regulation of mitotic cell cycle phase transitionGO:19019901300.017
regulation of cell cycle processGO:00105641810.017
negative regulation of cell differentiationGO:00455961430.017
mitotic nuclear divisionGO:00070672130.017
negative regulation of signal transductionGO:00099682060.017
regulation of wnt signaling pathwayGO:0030111680.017
chaeta developmentGO:0022416970.017
cellular macromolecule localizationGO:00707272200.017
protein k48 linked ubiquitinationGO:007093630.017
transcription from rna polymerase ii promoterGO:00063663680.017
positive regulation of gtpase activityGO:0043547430.017
ribonucleotide metabolic processGO:00092591450.017
germ line stem cell maintenanceGO:0030718500.017
spermatogenesisGO:00072832000.017
cell agingGO:000756920.017
establishment of protein localizationGO:00451841630.017
protein acetylationGO:0006473390.017
stem cell maintenanceGO:0019827670.017
asymmetric stem cell divisionGO:0098722490.017
protein acylationGO:0043543420.017
oocyte differentiationGO:00099941450.017
embryonic morphogenesisGO:00485982060.016
regulation of endocytosisGO:0030100370.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.016
peptidyl lysine modificationGO:0018205570.016
establishment of spindle orientationGO:0051294180.016
secondary metabolic processGO:0019748750.016
cellular component assembly involved in morphogenesisGO:00109271510.016
aromatic compound catabolic processGO:00194391660.016
response to extracellular stimulusGO:00099911160.016
cellular macromolecule catabolic processGO:00442651360.016
cell deathGO:00082192790.016
negative regulation of rna metabolic processGO:00512532510.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
stem cell proliferationGO:0072089880.016
cranial nerve developmentGO:002154510.016
ubiquitin dependent protein catabolic processGO:0006511780.016
dorsal ventral axon guidanceGO:003356320.015
response to biotic stimulusGO:00096072940.015
response to other organismGO:00517072930.015
cellular response to chemical stimulusGO:00708871990.015
actin cytoskeleton organizationGO:00300362060.015
cell cycle checkpointGO:0000075950.015
rna processingGO:00063961470.015
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.015
negative regulation of phosphorylationGO:0042326350.015
dorsal ventral axis specificationGO:0009950660.015
regulation of synapse assemblyGO:0051963940.015
regulation of programmed cell deathGO:00430671520.015
erbb signaling pathwayGO:0038127580.015
regulation of protein modification by small protein conjugation or removalGO:1903320250.015
centrosome cycleGO:00070981370.015
regulation of stress activated mapk cascadeGO:0032872410.015
compound eye morphogenesisGO:00017452490.015
monocarboxylic acid transportGO:001571830.015
fluid transportGO:0042044190.015
response to organic substanceGO:00100332840.015
regulation of protein stabilityGO:0031647430.015
small gtpase mediated signal transductionGO:0007264880.015
organophosphate metabolic processGO:00196371950.015
endocytosisGO:00068973100.014
deathGO:00162652840.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
negative regulation of cell cycle phase transitionGO:19019881030.014
compound eye photoreceptor developmentGO:0042051780.014
mitotic cell cycle checkpointGO:0007093880.014
response to heatGO:0009408630.014
regulation of synaptic growth at neuromuscular junctionGO:0008582890.014
regulation of neuromuscular synaptic transmissionGO:1900073150.014
larval behaviorGO:0030537420.014
proteolysisGO:00065081920.014
regulation of apoptotic processGO:00429811300.014
rho protein signal transductionGO:0007266140.014
establishment of tissue polarityGO:0007164870.014
neuron projection extensionGO:1990138320.014
organelle assemblyGO:00709251980.014
purine nucleoside catabolic processGO:00061521120.014
spermatid developmentGO:0007286980.014
organophosphate biosynthetic processGO:0090407460.014
single organism carbohydrate metabolic processGO:0044723720.014
regulation of cellular amine metabolic processGO:003323830.014
determination of adult lifespanGO:00083401370.014
positive regulation of wnt signaling pathwayGO:0030177250.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
negative regulation of multicellular organismal processGO:00512411420.014
signal transduction by phosphorylationGO:00230141070.014
phosphatidylinositol mediated signalingGO:004801540.014
regulation of cellular catabolic processGO:00313291570.014
stress activated protein kinase signaling cascadeGO:0031098550.014
notch signaling pathwayGO:00072191200.014
actin filament based movementGO:0030048260.013
positive regulation of intracellular signal transductionGO:19025331160.013
organic acid metabolic processGO:00060821030.013
peripheral nervous system developmentGO:0007422520.013
positive regulation of nervous system developmentGO:0051962690.013
protein transportGO:00150311550.013
organic substance catabolic processGO:19015753080.013
regulation of synapse organizationGO:00508071100.013
eye photoreceptor cell developmentGO:0042462810.013
positive regulation of cell motilityGO:200014730.013
positive regulation of transportGO:0051050920.013
regulation of establishment of protein localizationGO:0070201610.013
mitotic sister chromatid segregationGO:0000070870.013
leg disc developmentGO:0035218920.013
response to organophosphorusGO:004668320.013
neurological system processGO:00508773580.013
humoral immune responseGO:00069591170.013
response to oxygen containing compoundGO:19017002000.013
cellular protein localizationGO:00346131600.013
oxoacid metabolic processGO:00434361030.013
male mating behaviorGO:0060179700.013
protein complex biogenesisGO:00702712010.013
nucleotide metabolic processGO:00091171610.013
neural retina developmentGO:000340740.013
ribonucleoside metabolic processGO:00091191270.012
regulation of mapk cascadeGO:0043408920.012
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.012
regulation of cellular localizationGO:00603411360.012
organelle localizationGO:00516401480.012
axis specificationGO:00097981670.012
regulation of nucleocytoplasmic transportGO:0046822350.012
organonitrogen compound biosynthetic processGO:19015661170.012
defense responseGO:00069523000.012
cell junction organizationGO:0034330570.012
tripartite regional subdivisionGO:00073511030.012
heterocycle catabolic processGO:00467001660.012
cellular macromolecular complex assemblyGO:00346221530.012
kidney developmentGO:000182230.012
cortical cytoskeleton organizationGO:0030865290.012
positive regulation of cellular catabolic processGO:0031331950.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of endopeptidase activityGO:0052548360.012
negative regulation of cell cycle processGO:00109481090.012
regulation of cell cycle g1 s phase transitionGO:1902806230.012
compound eye photoreceptor cell differentiationGO:00017511400.012
jak stat cascadeGO:0007259490.012
limb developmentGO:006017310.012
neuromuscular junction developmentGO:00075281490.012
nucleoside triphosphate catabolic processGO:00091431080.012
glycoprotein metabolic processGO:0009100410.012
regulation of intracellular protein transportGO:0033157460.012
chromosome segregationGO:00070591570.012
positive regulation of hydrolase activityGO:0051345780.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
nucleobase containing small molecule metabolic processGO:00550861740.012
cellular response to decreased oxygen levelsGO:0036294300.012
circadian behaviorGO:0048512760.012
negative regulation of cellular protein metabolic processGO:0032269850.012
regulation of cytoplasmic transportGO:1903649470.012
negative regulation of cell deathGO:0060548810.012
cytoplasm organizationGO:0007028640.012
signal transduction in response to dna damageGO:004277030.012
imaginal disc derived leg segmentationGO:0036011260.012
organelle fissionGO:00482853400.011
carboxylic acid metabolic processGO:0019752920.011
regulation of jnk cascadeGO:0046328400.011
positive regulation of molecular functionGO:00440931360.011
asymmetric cell divisionGO:0008356370.011
neuromuscular synaptic transmissionGO:0007274670.011
regulation of immune system processGO:00026821760.011
neuroblast proliferationGO:0007405740.011
positive regulation of cell migrationGO:003033520.011
translationGO:0006412690.011
negative regulation of biosynthetic processGO:00098902770.011
protein depolymerizationGO:0051261310.011
negative regulation of synaptic transmissionGO:0050805120.011
cell cycle arrestGO:000705040.011
wing disc pattern formationGO:0035222660.011
sensory perceptionGO:00076001960.011
nitrogen compound transportGO:0071705850.011
regulation of translationGO:0006417560.011
developmental programmed cell deathGO:00106231380.011
meiosis iGO:0007127590.011
regulation of meiosisGO:004002030.011
cellular response to endogenous stimulusGO:0071495800.011
compound eye developmentGO:00487493070.011
regulation of antimicrobial humoral responseGO:0002759500.011
stress activated mapk cascadeGO:0051403520.011
renal system developmentGO:0072001720.011
negative regulation of response to stimulusGO:00485852580.011
immune responseGO:00069552460.011
regulation of catabolic processGO:00098941700.011
endodermal cell fate commitmentGO:000171130.011
response to lipopolysaccharideGO:003249640.011
epithelial cell migrationGO:00106311480.011
positive regulation of gtp catabolic processGO:0033126430.011
inositol lipid mediated signalingGO:004801740.011
necrotic cell deathGO:007026510.011
brain developmentGO:00074201200.011
embryo development ending in birth or egg hatchingGO:00097921520.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.011
periodic partitioningGO:0007365290.011
cellular response to oxygen levelsGO:0071453300.010
morphogenesis of a branching structureGO:0001763450.010
protein localizationGO:00081042840.010
ribose phosphate metabolic processGO:00196931450.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.010
positive regulation of phosphate metabolic processGO:00459371390.010
stem cell differentiationGO:00488631170.010
negative regulation of transcription dna templatedGO:00458922370.010
nephron developmentGO:007200630.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
negative regulation of protein metabolic processGO:0051248850.010
synaptic transmissionGO:00072682880.010
synaptic vesicle localizationGO:0097479530.010
cell junction assemblyGO:0034329420.010
positive regulation of neurogenesisGO:0050769410.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.010
regulation of cellular amide metabolic processGO:0034248390.010
multicellular organismal agingGO:00102591400.010
negative regulation of mitotic cell cycleGO:00459301090.010

gukh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
nervous system diseaseDOID:86300.066
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.013