IMP: Integrative Multi-species Prediction

Drosophila melanogaster

4 known processes

CG17919 (Dmel_CG17919)

CG17919 gene product from transcript CG17919-RA

(Aliases: Dmel\CG17919)

FLYBASE: FBgn0037433
Entrez: 40780
UniProtKB: Q9VI09

Process Predictions
Disease Predictions

CG17919 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
pigment metabolic process	GO:0042440	84	0.693
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.425
detection of stimulus	GO:0051606	156	0.324
detection of abiotic stimulus	GO:0009582	66	0.255
detection of light stimulus	GO:0009583	58	0.237
detection of external stimulus	GO:0009581	66	0.223
eye pigment metabolic process	GO:0042441	33	0.210
pigment metabolic process involved in pigmentation	GO:0043474	33	0.203
pigment biosynthetic process	GO:0046148	36	0.177
developmental pigmentation	GO:0048066	68	0.163
phototransduction	GO:0007602	52	0.146
response to light stimulus	GO:0009416	124	0.139
single organism biosynthetic process	GO:0044711	206	0.110
regulation of immune response	GO:0050776	118	0.109	Fly
eye pigment biosynthetic process	GO:0006726	32	0.105
eye pigmentation	GO:0048069	43	0.092
response to radiation	GO:0009314	155	0.091
pigmentation	GO:0043473	75	0.089
rhodopsin metabolic process	GO:0046154	10	0.088
response to biotic stimulus	GO:0009607	294	0.080	Fly
regulation of response to stress	GO:0080134	200	0.076
positive regulation of response to stimulus	GO:0048584	323	0.068
response to abiotic stimulus	GO:0009628	341	0.064
regionalization	GO:0003002	416	0.063
defense response to bacterium	GO:0042742	178	0.061	Fly
response to other organism	GO:0051707	293	0.059	Fly
defense response to other organism	GO:0098542	225	0.058	Fly
regulation of cellular protein metabolic process	GO:0032268	243	0.050
regulation of immune system process	GO:0002682	176	0.048	Fly
extracellular structure organization	GO:0043062	46	0.045
response to external biotic stimulus	GO:0043207	293	0.045	Fly
organonitrogen compound metabolic process	GO:1901564	318	0.043
immune response	GO:0006955	246	0.043	Fly
rhodopsin biosynthetic process	GO:0016063	9	0.042
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.040
defense response	GO:0006952	300	0.035	Fly
response to bacterium	GO:0009617	198	0.034	Fly
immune system process	GO:0002376	347	0.034	Fly
axis specification	GO:0009798	167	0.034
hormone catabolic process	GO:0042447	3	0.033
regulation of defense response	GO:0031347	102	0.032
positive regulation of cell communication	GO:0010647	250	0.032
positive regulation of signaling	GO:0023056	243	0.030
organonitrogen compound biosynthetic process	GO:1901566	117	0.030
response to nutrient levels	GO:0031667	114	0.030
negative regulation of gene expression	GO:0010629	387	0.029
cell death	GO:0008219	279	0.029
dorsal ventral pattern formation	GO:0009953	133	0.028
body morphogenesis	GO:0010171	2	0.027
cuticle development	GO:0042335	86	0.027
pattern recognition receptor signaling pathway	GO:0002221	2	0.027
dorsal ventral axis specification	GO:0009950	66	0.026
vesicle mediated transport	GO:0016192	381	0.026
regulation of protein metabolic process	GO:0051246	256	0.026
single organism behavior	GO:0044708	391	0.026
positive regulation of hemocyte proliferation	GO:0035208	4	0.025
phagocytosis	GO:0006909	215	0.024
chitin based cuticle development	GO:0040003	49	0.024
positive regulation of signal transduction	GO:0009967	223	0.023
response to extracellular stimulus	GO:0009991	116	0.022
regulation of response to biotic stimulus	GO:0002831	63	0.022	Fly
negative regulation of cellular metabolic process	GO:0031324	382	0.022
connective tissue development	GO:0061448	3	0.021
biological adhesion	GO:0022610	138	0.021
small molecule metabolic process	GO:0044281	305	0.021
positive regulation of immune response	GO:0050778	63	0.021
negative regulation of response to stimulus	GO:0048585	258	0.021
cellular protein modification process	GO:0006464	438	0.021
regulation of multicellular organismal development	GO:2000026	414	0.021
response to organic substance	GO:0010033	284	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
lateral inhibition	GO:0046331	206	0.020
regulation of defense response to bacterium	GO:1900424	30	0.020
extracellular matrix organization	GO:0030198	32	0.020
endocytosis	GO:0006897	310	0.020
regulation of phosphorus metabolic process	GO:0051174	210	0.019
spindle organization	GO:0007051	253	0.019
developmental growth	GO:0048589	280	0.019
regulation of response to external stimulus	GO:0032101	115	0.019	Fly
regulation of cell proliferation	GO:0042127	163	0.019
positive regulation of melanization defense response	GO:0035008	1	0.019
positive regulation of cell death	GO:0010942	69	0.019
neurological system process	GO:0050877	358	0.019
negative regulation of cellular component organization	GO:0051129	108	0.018
regulation of multi organism process	GO:0043900	131	0.018	Fly
epithelium migration	GO:0090132	148	0.018
death	GO:0016265	284	0.018
protein modification process	GO:0036211	438	0.018
wound healing	GO:0042060	75	0.018
regulation of innate immune response	GO:0045088	71	0.018
phenol containing compound metabolic process	GO:0018958	57	0.018
lipid localization	GO:0010876	54	0.018
regulation of anatomical structure morphogenesis	GO:0022603	242	0.017
antimicrobial humoral response	GO:0019730	99	0.017	Fly
single organism catabolic process	GO:0044712	228	0.017
regulation of molecular function	GO:0065009	217	0.017
ameboidal type cell migration	GO:0001667	151	0.017
reproductive behavior	GO:0019098	122	0.017
cellular catabolic process	GO:0044248	372	0.017
cellular amino acid metabolic process	GO:0006520	61	0.017
regulation of extracellular matrix organization	GO:1903053	4	0.017
cellular ketone metabolic process	GO:0042180	24	0.016
regulation of cell death	GO:0010941	173	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
negative regulation of extracellular matrix organization	GO:1903054	1	0.016
homeostatic process	GO:0042592	199	0.016
regulation of catalytic activity	GO:0050790	185	0.016
humoral immune response	GO:0006959	117	0.016	Fly
oxoacid metabolic process	GO:0043436	103	0.016
regulation of localization	GO:0032879	275	0.016
immune response activating signal transduction	GO:0002757	2	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
posttranscriptional regulation of gene expression	GO:0010608	145	0.015
response to alcohol	GO:0097305	95	0.015
cell migration	GO:0016477	238	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.015
protein phosphorylation	GO:0006468	169	0.015
neuron recognition	GO:0008038	101	0.015
cell proliferation	GO:0008283	299	0.015
positive regulation of multi organism process	GO:0043902	40	0.014
segmentation	GO:0035282	207	0.014
sensory perception	GO:0007600	196	0.014
appendage development	GO:0048736	401	0.014
organic acid metabolic process	GO:0006082	103	0.014
innate immune response	GO:0045087	144	0.014
response to wounding	GO:0009611	94	0.014
positive regulation of molecular function	GO:0044093	136	0.014
exocrine system development	GO:0035272	162	0.014
nuclear division	GO:0000280	332	0.014
response to oxygen containing compound	GO:1901700	200	0.014
wing disc morphogenesis	GO:0007472	344	0.014
positive regulation of cell migration	GO:0030335	2	0.014
catabolic process	GO:0009056	409	0.014
very long chain fatty acid metabolic process	GO:0000038	4	0.014
protein processing	GO:0016485	68	0.014
positive regulation of response to external stimulus	GO:0032103	44	0.013
camera type eye development	GO:0043010	4	0.013
synapse assembly	GO:0007416	143	0.013
regulation of catabolic process	GO:0009894	170	0.013
protein maturation	GO:0051604	71	0.013
activation of innate immune response	GO:0002218	4	0.013
immune response regulating signaling pathway	GO:0002764	2	0.013
multicellular organismal reproductive behavior	GO:0033057	110	0.013
positive regulation of cell motility	GO:2000147	3	0.013
programmed cell death	GO:0012501	257	0.013
intracellular signal transduction	GO:0035556	300	0.013
cellular amide metabolic process	GO:0043603	80	0.013
response to hexose	GO:0009746	3	0.012
response to organophosphorus	GO:0046683	2	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
mating behavior	GO:0007617	106	0.012
negative regulation of homeostatic process	GO:0032845	2	0.012
positive regulation of phosphate metabolic process	GO:0045937	139	0.012
positive regulation of immune system process	GO:0002684	68	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
salivary gland cell autophagic cell death	GO:0035071	83	0.012
organic substance catabolic process	GO:1901575	308	0.012
blastoderm segmentation	GO:0007350	159	0.012
regulation of cell cycle	GO:0051726	291	0.012
regulation of humoral immune response	GO:0002920	51	0.012	Fly
embryonic pattern specification	GO:0009880	174	0.012
imaginal disc derived appendage development	GO:0048737	399	0.012
peptide biosynthetic process	GO:0043043	42	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
cell adhesion	GO:0007155	136	0.012
epithelial cell differentiation	GO:0030855	322	0.012
adult behavior	GO:0030534	137	0.011
response to lipopolysaccharide	GO:0032496	4	0.011
ras protein signal transduction	GO:0007265	88	0.011
immune effector process	GO:0002252	98	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
macromolecular complex assembly	GO:0065003	256	0.011
gene silencing	GO:0016458	138	0.011
organic substance transport	GO:0071702	257	0.011
cell motility	GO:0048870	251	0.011
gland morphogenesis	GO:0022612	145	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
regulation of protein modification process	GO:0031399	112	0.011
anterior posterior axis specification embryo	GO:0008595	103	0.011
regulation of programmed cell death	GO:0043067	152	0.011
localization of cell	GO:0051674	257	0.011
appendage morphogenesis	GO:0035107	397	0.011
salivary gland development	GO:0007431	162	0.011
developmental programmed cell death	GO:0010623	138	0.011
mating	GO:0007618	120	0.011
defense response to gram positive bacterium	GO:0050830	41	0.011	Fly
positive regulation of phosphorus metabolic process	GO:0010562	139	0.010
positive regulation of gene expression	GO:0010628	290	0.010
hippo signaling	GO:0035329	20	0.010
regulation of extracellular matrix disassembly	GO:0010715	1	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
regulation of cellular amino acid metabolic process	GO:0006521	0	0.010
gland development	GO:0048732	191	0.010
compound eye morphogenesis	GO:0001745	249	0.010
sterol homeostasis	GO:0055092	4	0.010
phosphorylation	GO:0016310	294	0.010
benzene containing compound metabolic process	GO:0042537	3	0.010

CG17919 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.020
disease of metabolism	DOID:0014667	0.019
inherited metabolic disorder	DOID:655	0.019
nervous system disease	DOID:863	0.018
sensory system disease	DOID:0050155	0.011

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