Drosophila melanogaster

113 known processes

l(2)gd1 (Dmel_CG4713)

lethal (2) giant discs 1

(Aliases: l[[2]]gd,l(2)SH0495,Dmel\CG4713,lgd,l(2)gd,gd,SH495,CG4713,l(2)SH2 0495,l(2)giant disc)

l(2)gd1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell communicationGO:00106482230.648
epithelial cell developmentGO:00020642740.578
cell divisionGO:00513012480.536
regulation of epithelial cell proliferationGO:005067840.484
axon developmentGO:00615642970.373
developmental growthGO:00485892800.358
appendage morphogenesisGO:00351073970.338
cell maturationGO:00484691440.324
embryonic pattern specificationGO:00098801740.277
negative regulation of response to stimulusGO:00485852580.269
anterior posterior pattern specificationGO:00099521360.257
cell motilityGO:00488702510.244
negative regulation of transcription dna templatedGO:00458922370.242
stem cell developmentGO:0048864790.214
segmentationGO:00352822070.214
axonogenesisGO:00074092900.194
post embryonic appendage morphogenesisGO:00351203850.191
negative regulation of macromolecule biosynthetic processGO:00105582700.191
imaginal disc derived appendage morphogenesisGO:00351143950.190
imaginal disc pattern formationGO:0007447910.184
epithelial cell differentiationGO:00308553220.183
endosomal transportGO:0016197440.180
eye developmentGO:00016543230.173
positive regulation of gene expressionGO:00106282900.171
compound eye photoreceptor cell differentiationGO:00017511400.169
enzyme linked receptor protein signaling pathwayGO:00071671790.169
imaginal disc growthGO:0007446370.165
negative regulation of cellular metabolic processGO:00313243820.164
erbb signaling pathwayGO:0038127580.161
blastoderm segmentationGO:00073501590.161
growthGO:00400073590.158
protein modification processGO:00362114380.152
vesicle mediated transportGO:00161923810.148
negative regulation of signalingGO:00230572190.148
negative regulation of biosynthetic processGO:00098902770.137
negative regulation of nitrogen compound metabolic processGO:00511722650.137
cellular component assembly involved in morphogenesisGO:00109271510.127
negative regulation of cellular biosynthetic processGO:00313272770.127
mesenchymal cell differentiationGO:004876210.125
embryonic axis specificationGO:00005781070.123
localization of cellGO:00516742570.119
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.118
positive regulation of rna metabolic processGO:00512542710.114
negative regulation of signal transductionGO:00099682060.108
regionalizationGO:00030024160.105
regulation of nervous system developmentGO:00519602480.105
eye photoreceptor cell differentiationGO:00017541450.104
anterior posterior axis specificationGO:00099481090.094
adult locomotory behaviorGO:0008344760.093
cellular protein modification processGO:00064644380.091
appendage developmentGO:00487364010.089
eye morphogenesisGO:00485922600.089
compound eye morphogenesisGO:00017452490.083
establishment or maintenance of cell polarityGO:00071631670.082
tripartite regional subdivisionGO:00073511030.080
regulation of neuroblast proliferationGO:1902692340.080
neuron fate commitmentGO:0048663500.078
organonitrogen compound metabolic processGO:19015643180.077
eye photoreceptor cell fate commitmentGO:0042706370.074
ovarian follicle cell developmentGO:00307072480.074
phosphorylationGO:00163102940.072
epidermal growth factor receptor signaling pathwayGO:0007173580.067
tissue deathGO:00162711020.066
imaginal disc derived appendage developmentGO:00487373990.063
negative regulation of rna biosynthetic processGO:19026792400.060
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.060
wing disc morphogenesisGO:00074723440.059
homeostatic processGO:00425921990.058
tissue morphogenesisGO:00487292970.058
mesenchymal cell developmentGO:001403110.057
negative regulation of gene expressionGO:00106293870.056
negative regulation of rna metabolic processGO:00512532510.055
establishment of cell polarityGO:0030010400.052
compound eye developmentGO:00487493070.050
chemotaxisGO:00069352490.050
regulation of reproductive processGO:2000241540.049
lateral inhibitionGO:00463312060.048
segment polarity determinationGO:0007367250.048
mating behaviorGO:00076171060.048
wing disc pattern formationGO:0035222660.047
regulation of imaginal disc growthGO:0045570260.047
taxisGO:00423303040.047
muscle fiber developmentGO:0048747120.046
immune system processGO:00023763470.046
dendrite morphogenesisGO:00488131990.045
regulation of hemocyte proliferationGO:0035206370.044
muscle organ developmentGO:00075171270.043
regulation of multicellular organismal developmentGO:20000264140.043
notch signaling pathwayGO:00072191200.042
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.041
rhythmic processGO:00485111060.041
photoreceptor cell differentiationGO:00465301700.041
feeding behaviorGO:0007631500.040
axon guidanceGO:00074112330.039
columnar cuboidal epithelial cell developmentGO:00020662490.038
positive energy taxisGO:005212830.038
regulation of cell differentiationGO:00455953020.037
smoothened signaling pathwayGO:0007224490.037
multi multicellular organism processGO:00447061230.037
negative regulation of epithelial cell proliferationGO:005068040.037
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.037
embryonic development via the syncytial blastodermGO:00017001480.035
regulation of cell developmentGO:00602842150.035
circulatory system processGO:0003013370.035
regulation of epithelial cell differentiationGO:003085640.034
imaginal disc derived wing margin morphogenesisGO:0008587410.034
anterior posterior axis specification embryoGO:00085951030.034
regulation of erbb signaling pathwayGO:1901184420.034
catabolic processGO:00090564090.033
macromolecule catabolic processGO:00090571610.033
positive regulation of cellular biosynthetic processGO:00313283160.032
protein modification by small protein conjugationGO:0032446790.032
eggshell chorion assemblyGO:0007306660.031
negative regulation of nucleobase containing compound metabolic processGO:00459342610.031
cell migrationGO:00164772380.031
wing disc dorsal ventral pattern formationGO:0048190470.031
cell deathGO:00082192790.031
response to extracellular stimulusGO:00099911160.031
locomotory behaviorGO:00076261760.031
phagocytosisGO:00069092150.030
protein ubiquitinationGO:0016567700.029
positive regulation of nitrogen compound metabolic processGO:00511733540.029
stem cell differentiationGO:00488631170.029
axis specificationGO:00097981670.028
chaeta developmentGO:0022416970.028
positive regulation of rna biosynthetic processGO:19026802660.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.027
regulation of viral genome replicationGO:004506940.027
regulation of cell proliferationGO:00421271630.026
imaginal disc derived leg morphogenesisGO:0007480800.026
connective tissue developmentGO:006144830.026
cell fate determinationGO:0001709910.026
developmental maturationGO:00217001720.025
response to organic substanceGO:00100332840.025
columnar cuboidal epithelial cell differentiationGO:00020652560.024
positive regulation of nucleic acid templated transcriptionGO:19035082660.024
negative regulation of nucleic acid templated transcriptionGO:19035072400.024
proteolysis involved in cellular protein catabolic processGO:0051603830.024
sensory organ morphogenesisGO:00905962600.024
regulation of multi organism processGO:00439001310.023
programmed cell deathGO:00125012570.023
dorsal ventral pattern formationGO:00099531330.022
oocyte microtubule cytoskeleton organizationGO:0016325350.022
carbohydrate derivative metabolic processGO:19011352170.022
cell cell signaling involved in cell fate commitmentGO:00451682100.021
positive regulation of transcription dna templatedGO:00458932660.021
establishment or maintenance of cytoskeleton polarityGO:0030952440.021
stem cell maintenanceGO:0019827670.021
organic substance catabolic processGO:19015753080.020
dorsal ventral pattern formation imaginal discGO:0007450510.020
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.019
pupal developmentGO:0035209110.018
epidermal cell differentiationGO:0009913510.018
chorion containing eggshell formationGO:00073041050.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
leg disc morphogenesisGO:0007478800.017
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.017
cellular lipid metabolic processGO:0044255830.017
regulation of programmed cell deathGO:00430671520.016
cellular amine metabolic processGO:0044106120.016
cellular response to growth factor stimulusGO:0071363300.016
embryonic morphogenesisGO:00485982060.016
morphogenesis of follicular epitheliumGO:0016333360.015
multicellular organismal reproductive behaviorGO:00330571100.015
camera type eye developmentGO:004301040.015
neuroblast differentiationGO:0014016290.015
regulation of neurogenesisGO:00507671580.015
chaeta morphogenesisGO:0008407420.015
regulation of developmental growthGO:00486381740.014
regulation of cell deathGO:00109411730.014
regulation of cellular catabolic processGO:00313291570.014
cell proliferationGO:00082832990.014
adult behaviorGO:00305341370.014
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.014
cellular protein catabolic processGO:0044257830.014
negative regulation of developmental processGO:00510932010.013
regulation of neuron differentiationGO:00456641030.013
regulation of wnt signaling pathwayGO:0030111680.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.013
oocyte anterior posterior axis specificationGO:0007314720.013
imaginal disc derived wing morphogenesisGO:00074763370.013
positive regulation of signal transductionGO:00099672230.013
regulation of growthGO:00400082330.013
transcription from rna polymerase ii promoterGO:00063663680.013
dorsal appendage formationGO:0046843470.012
regulation of cell cycle processGO:00105641810.012
intracellular signal transductionGO:00355563000.012
histolysisGO:00075591020.012
regulation of phosphorylationGO:00423251470.012
epidermis developmentGO:0008544650.012
renal tubule developmentGO:0061326640.012
amine metabolic processGO:0009308120.012
multicellular organismal agingGO:00102591400.012
head developmentGO:00603221350.012
maternal determination of anterior posterior axis embryoGO:0008358740.012
organonitrogen compound biosynthetic processGO:19015661170.012
negative regulation of cell differentiationGO:00455961430.011
synaptic vesicle localizationGO:0097479530.011
salivary gland cell autophagic cell deathGO:0035071830.011
organic acid metabolic processGO:00060821030.011
modification dependent protein catabolic processGO:0019941780.011
positive regulation of bindingGO:005109940.011
positive regulation of biosynthetic processGO:00098913160.011
digestive tract morphogenesisGO:00485461270.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
autophagyGO:00069141080.011
regulation of apoptotic processGO:00429811300.011
neurological system processGO:00508773580.011
mesoderm developmentGO:0007498780.011
agingGO:00075681430.011
oxoacid metabolic processGO:00434361030.011
positive regulation of macromolecule metabolic processGO:00106044050.011
ameboidal type cell migrationGO:00016671510.010
regulation of notch signaling pathwayGO:00085931000.010
cellular response to organic substanceGO:00713101320.010
determination of adult lifespanGO:00083401370.010
regulation of timing of cell differentiationGO:004850510.010
stem cell proliferationGO:0072089880.010
reproductive system developmentGO:0061458740.010
regulation of cellular amino acid metabolic processGO:000652100.010
deathGO:00162652840.010

l(2)gd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049