IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG10188 (Dmel_CG10188)

CG10188 gene product from transcript CG10188-RB

(Aliases: Dmel\CG10188)

FLYBASE: FBgn0032796
Entrez: 35237
UniProtKB: M9PBE1
UniProtKB: Q9VIV0

Process Predictions
Disease Predictions

CG10188 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
eye development	GO:0001654	323	0.166
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.119
neuron projection guidance	GO:0097485	241	0.118
regulation of cellular component biogenesis	GO:0044087	201	0.113
r3 r4 cell differentiation	GO:0048056	12	0.108
axon guidance	GO:0007411	233	0.107
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.104
epithelial cell development	GO:0002064	274	0.101
actin cytoskeleton organization	GO:0030036	206	0.094	Human Mouse
cell projection assembly	GO:0030031	94	0.093
regionalization	GO:0003002	416	0.091
cellular component assembly involved in morphogenesis	GO:0010927	151	0.088
axonogenesis	GO:0007409	290	0.087
epithelial cell migration	GO:0010631	148	0.082
actin filament based process	GO:0030029	220	0.080	Human Mouse
imaginal disc derived appendage development	GO:0048737	399	0.074
post embryonic appendage morphogenesis	GO:0035120	385	0.069
actin filament organization	GO:0007015	126	0.065	Human Mouse
endocytosis	GO:0006897	310	0.065
sensory organ morphogenesis	GO:0090596	260	0.065
wing disc morphogenesis	GO:0007472	344	0.065
appendage morphogenesis	GO:0035107	397	0.064
ras protein signal transduction	GO:0007265	88	0.063	Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.060
positive regulation of molecular function	GO:0044093	136	0.058	Human Mouse
eye morphogenesis	GO:0048592	260	0.058
chemotaxis	GO:0006935	249	0.058
purine nucleoside metabolic process	GO:0042278	127	0.055	Human Mouse
tissue migration	GO:0090130	155	0.052
purine ribonucleotide metabolic process	GO:0009150	145	0.050	Human Mouse
compound eye development	GO:0048749	307	0.050
regulation of cellular amino acid metabolic process	GO:0006521	0	0.049
cellular nitrogen compound catabolic process	GO:0044270	165	0.049	Human Mouse
regulation of hydrolase activity	GO:0051336	97	0.049	Human Mouse
salivary gland morphogenesis	GO:0007435	145	0.048
nucleobase containing small molecule metabolic process	GO:0055086	174	0.048	Human Mouse
compound eye morphogenesis	GO:0001745	249	0.046
appendage development	GO:0048736	401	0.046
protein ubiquitination	GO:0016567	70	0.046
catabolic process	GO:0009056	409	0.046	Human Mouse
small gtpase mediated signal transduction	GO:0007264	88	0.045	Human Mouse
nucleoside triphosphate metabolic process	GO:0009141	120	0.045	Human Mouse
actomyosin structure organization	GO:0031032	56	0.045
imaginal disc derived leg morphogenesis	GO:0007480	80	0.044
exocrine system development	GO:0035272	162	0.043
regulation of synapse structure and activity	GO:0050803	128	0.041
response to external biotic stimulus	GO:0043207	293	0.041
organic cyclic compound catabolic process	GO:1901361	168	0.040	Human Mouse
positive regulation of cellular catabolic process	GO:0031331	95	0.040	Human Mouse
regulation of cell development	GO:0060284	215	0.039	Mouse
protein localization	GO:0008104	284	0.038
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.038	Human Mouse
gtp metabolic process	GO:0046039	72	0.038	Human Mouse
imaginal disc derived wing morphogenesis	GO:0007476	337	0.037
small molecule metabolic process	GO:0044281	305	0.037	Human Mouse
organophosphate metabolic process	GO:0019637	195	0.036	Human Mouse
cellular lipid metabolic process	GO:0044255	83	0.036
nucleoside metabolic process	GO:0009116	127	0.036	Human Mouse
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.036	Human Mouse
positive regulation of hydrolase activity	GO:0051345	78	0.035	Human Mouse
eye photoreceptor cell differentiation	GO:0001754	145	0.035
ovarian follicle cell migration	GO:0007297	121	0.035
salivary gland development	GO:0007431	162	0.034
taxis	GO:0042330	304	0.034
developmental programmed cell death	GO:0010623	138	0.033
golgi organization	GO:0007030	66	0.033
nuclear division	GO:0000280	332	0.033
nucleoside triphosphate catabolic process	GO:0009143	108	0.033	Human Mouse
centrosome organization	GO:0051297	163	0.032
regulation of neuron differentiation	GO:0045664	103	0.032
regulation of actin cytoskeleton organization	GO:0032956	42	0.032
vesicle mediated transport	GO:0016192	381	0.031
carbohydrate derivative metabolic process	GO:1901135	217	0.031	Human Mouse
cellular amine metabolic process	GO:0044106	12	0.031
cellular catabolic process	GO:0044248	372	0.031	Human Mouse
regulation of tube size open tracheal system	GO:0035151	43	0.031
epithelial cell differentiation	GO:0030855	322	0.031
cellular protein modification process	GO:0006464	438	0.031	Human
tissue morphogenesis	GO:0048729	297	0.031
organic substance catabolic process	GO:1901575	308	0.031	Human Mouse
guanosine containing compound catabolic process	GO:1901069	74	0.030	Human Mouse
guanosine containing compound metabolic process	GO:1901068	74	0.030	Human Mouse
lateral inhibition	GO:0046331	206	0.030
nucleobase containing compound catabolic process	GO:0034655	165	0.030	Human Mouse
negative regulation of biosynthetic process	GO:0009890	277	0.029
single organism catabolic process	GO:0044712	228	0.029	Human Mouse
ovarian follicle cell development	GO:0030707	248	0.029
phagocytosis	GO:0006909	215	0.029
regulation of anatomical structure size	GO:0090066	163	0.029
cilium organization	GO:0044782	41	0.029
eggshell chorion assembly	GO:0007306	66	0.029
regulation of notch signaling pathway	GO:0008593	100	0.029
establishment of localization in cell	GO:0051649	402	0.029	Mouse
leg disc morphogenesis	GO:0007478	80	0.028
heterocycle catabolic process	GO:0046700	166	0.028	Human Mouse
regulation of ras gtpase activity	GO:0032318	38	0.028	Human Mouse
cell adhesion	GO:0007155	136	0.028
camera type eye development	GO:0043010	4	0.027
photoreceptor cell differentiation	GO:0046530	170	0.027
purine nucleotide metabolic process	GO:0006163	146	0.027	Human Mouse
regulation of cytoskeleton organization	GO:0051493	89	0.027	Human
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.027	Human Mouse
notch signaling pathway	GO:0007219	120	0.027
regulation of molecular function	GO:0065009	217	0.027	Human Mouse
immune system process	GO:0002376	347	0.027
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.026	Human Mouse
gland morphogenesis	GO:0022612	145	0.026
regulation of cell morphogenesis	GO:0022604	163	0.026	Human
amine metabolic process	GO:0009308	12	0.025
ion transport	GO:0006811	145	0.025
leg disc development	GO:0035218	92	0.025
regulation of cellular catabolic process	GO:0031329	157	0.025	Human Mouse
endomembrane system organization	GO:0010256	119	0.024
negative regulation of response to stimulus	GO:0048585	258	0.024
regulation of cell differentiation	GO:0045595	302	0.024	Mouse
organonitrogen compound metabolic process	GO:1901564	318	0.024	Human Mouse
organelle assembly	GO:0070925	198	0.024
macromolecular complex assembly	GO:0065003	256	0.024
organic acid metabolic process	GO:0006082	103	0.023
purine ribonucleotide catabolic process	GO:0009154	109	0.023	Human Mouse
purine ribonucleoside metabolic process	GO:0046128	127	0.023	Human Mouse
axon development	GO:0061564	297	0.023
regulation of cellular amine metabolic process	GO:0033238	3	0.023
ribonucleoside catabolic process	GO:0042454	112	0.023	Human Mouse
aromatic compound catabolic process	GO:0019439	166	0.023	Human Mouse
intracellular transport	GO:0046907	228	0.023
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.023	Human Mouse
dendrite development	GO:0016358	204	0.023
response to alcohol	GO:0097305	95	0.022
protein complex biogenesis	GO:0070271	201	0.022
regulation of purine nucleotide catabolic process	GO:0033121	48	0.022	Human Mouse
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022	Human Mouse
cellular amino acid metabolic process	GO:0006520	61	0.022
nucleotide metabolic process	GO:0009117	161	0.022	Human Mouse
cell recognition	GO:0008037	102	0.022
regulation of multicellular organismal development	GO:2000026	414	0.022	Mouse
regulation of ras protein signal transduction	GO:0046578	93	0.022	Human Mouse
phosphorylation	GO:0016310	294	0.022	Human
regulation of nucleotide catabolic process	GO:0030811	48	0.022	Human Mouse
regulation of tube length open tracheal system	GO:0035159	24	0.022
cilium morphogenesis	GO:0060271	39	0.021
nucleotide catabolic process	GO:0009166	109	0.021	Human Mouse
lipid metabolic process	GO:0006629	121	0.021
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.021	Human
negative regulation of cell communication	GO:0010648	223	0.021
nucleoside phosphate metabolic process	GO:0006753	162	0.021	Human Mouse
positive regulation of phosphate metabolic process	GO:0045937	139	0.020	Human Mouse
regulation of intracellular signal transduction	GO:1902531	236	0.020	Human Mouse
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.020	Human Mouse
cellular macromolecule catabolic process	GO:0044265	136	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
single organism behavior	GO:0044708	391	0.020
death	GO:0016265	284	0.020
histone h4 k20 methylation	GO:0034770	4	0.020
dorsal ventral pattern formation	GO:0009953	133	0.019
columnar cuboidal epithelial cell development	GO:0002066	249	0.019
epithelium migration	GO:0090132	148	0.019
meiotic cell cycle process	GO:1903046	132	0.019
oxoacid metabolic process	GO:0043436	103	0.019
purine nucleotide catabolic process	GO:0006195	109	0.019	Human Mouse
ribonucleotide metabolic process	GO:0009259	145	0.019	Human Mouse
cytokinesis	GO:0000910	90	0.019
protein complex assembly	GO:0006461	200	0.019
chromosome organization	GO:0051276	360	0.019
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.018
positive regulation of cell communication	GO:0010647	250	0.018
regulation of nucleotide metabolic process	GO:0006140	62	0.018	Human Mouse
negative regulation of signal transduction	GO:0009968	206	0.018
photoreceptor cell development	GO:0042461	96	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
organophosphate catabolic process	GO:0046434	112	0.018	Human Mouse
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.018
embryonic pattern specification	GO:0009880	174	0.018
regulation of neuron projection development	GO:0010975	69	0.017
negative regulation of rna metabolic process	GO:0051253	251	0.017
regulation of catalytic activity	GO:0050790	185	0.017	Human Mouse
single organism intracellular transport	GO:1902582	207	0.017
cellular ketone metabolic process	GO:0042180	24	0.017
adult behavior	GO:0030534	137	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.017	Human Mouse
regulation of actin filament based process	GO:0032970	42	0.017
muscle cell differentiation	GO:0042692	103	0.017
regulation of cellular component size	GO:0032535	98	0.016
epidermis development	GO:0008544	65	0.016
positive regulation of biosynthetic process	GO:0009891	316	0.016	Human
regulation of cellular protein metabolic process	GO:0032268	243	0.016	Human
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016	Human Mouse
establishment of planar polarity	GO:0001736	87	0.016
negative regulation of signaling	GO:0023057	219	0.016
protein modification by small protein conjugation or removal	GO:0070647	106	0.016
protein modification by small protein conjugation	GO:0032446	79	0.016
cellular macromolecule localization	GO:0070727	220	0.016
biological adhesion	GO:0022610	138	0.016
autophagic cell death	GO:0048102	83	0.016
ribose phosphate metabolic process	GO:0019693	145	0.016	Human Mouse
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
cilium assembly	GO:0042384	38	0.016
negative regulation of notch signaling pathway	GO:0045746	41	0.015
establishment or maintenance of cell polarity	GO:0007163	167	0.015	Mouse
positive regulation of catalytic activity	GO:0043085	118	0.015	Human Mouse
anterior posterior pattern specification	GO:0009952	136	0.015
rac protein signal transduction	GO:0016601	3	0.015
regulation of protein metabolic process	GO:0051246	256	0.015	Human
jak stat cascade	GO:0007259	49	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.015	Human Mouse
microtubule organizing center organization	GO:0031023	168	0.015
camera type eye morphogenesis	GO:0048593	2	0.015
ribonucleotide catabolic process	GO:0009261	109	0.015	Human Mouse
tissue death	GO:0016271	102	0.015
compound eye photoreceptor development	GO:0042051	78	0.015
glycosyl compound metabolic process	GO:1901657	127	0.014	Human Mouse
positive regulation of cellular component biogenesis	GO:0044089	80	0.014
cytoplasmic transport	GO:0016482	130	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.014
endosomal transport	GO:0016197	44	0.014
mapk cascade	GO:0000165	107	0.014
synapse assembly	GO:0007416	143	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014	Human Mouse
neuron recognition	GO:0008038	101	0.014
response to biotic stimulus	GO:0009607	294	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
localization of cell	GO:0051674	257	0.014
nucleoside phosphate catabolic process	GO:1901292	110	0.014	Human Mouse
cell death	GO:0008219	279	0.014
regulation of nervous system development	GO:0051960	248	0.014	Mouse
mitotic spindle organization	GO:0007052	220	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014	Human Mouse
respiratory system development	GO:0060541	213	0.014
nucleus organization	GO:0006997	45	0.014
morphogenesis of an epithelium	GO:0002009	276	0.014
segmentation	GO:0035282	207	0.014
single organism cellular localization	GO:1902580	180	0.014	Mouse
purine containing compound metabolic process	GO:0072521	155	0.014	Human Mouse
gland development	GO:0048732	191	0.014
glycosyl compound catabolic process	GO:1901658	112	0.013	Human Mouse
single organismal cell cell adhesion	GO:0016337	45	0.013
spermatogenesis	GO:0007283	200	0.013
positive regulation of nucleoside metabolic process	GO:0045979	47	0.013	Human Mouse
cell motility	GO:0048870	251	0.013
histolysis	GO:0007559	102	0.013
blastoderm segmentation	GO:0007350	159	0.013
dendrite morphogenesis	GO:0048813	199	0.013
gtp catabolic process	GO:0006184	72	0.013	Human Mouse
developmental growth involved in morphogenesis	GO:0060560	65	0.013
single organism biosynthetic process	GO:0044711	206	0.013
salivary gland cell autophagic cell death	GO:0035071	83	0.013
positive regulation of ras gtpase activity	GO:0032320	36	0.013	Human Mouse
macromolecule catabolic process	GO:0009057	161	0.013
regulation of mapk cascade	GO:0043408	92	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
negative regulation of cellular metabolic process	GO:0031324	382	0.013
ameboidal type cell migration	GO:0001667	151	0.013
positive regulation of nucleotide metabolic process	GO:0045981	55	0.013	Human Mouse
synapse organization	GO:0050808	196	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013	Human Mouse
proteolysis	GO:0006508	192	0.013
body morphogenesis	GO:0010171	2	0.013
regulation of immune system process	GO:0002682	176	0.013
nucleoside catabolic process	GO:0009164	112	0.013	Human Mouse
positive regulation of protein metabolic process	GO:0051247	128	0.012	Human
mesenchymal cell differentiation	GO:0048762	1	0.012
positive regulation of response to stimulus	GO:0048584	323	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.012	Human
regulation of transport	GO:0051049	181	0.012
single organism cell adhesion	GO:0098602	47	0.012
cellularization	GO:0007349	90	0.012
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.012
regulation of cell projection organization	GO:0031344	92	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012	Human
response to bacterium	GO:0009617	198	0.012
regulation of response to stress	GO:0080134	200	0.012
chaeta development	GO:0022416	97	0.012
connective tissue development	GO:0061448	3	0.012
regulation of rac protein signal transduction	GO:0035020	3	0.012
male gamete generation	GO:0048232	201	0.012
positive regulation of cell differentiation	GO:0045597	64	0.012
regulation of localization	GO:0032879	275	0.012
positive regulation of signaling	GO:0023056	243	0.012
protein phosphorylation	GO:0006468	169	0.012	Human
positive regulation of neurogenesis	GO:0050769	41	0.011
immune system development	GO:0002520	57	0.011
growth	GO:0040007	359	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
microtubule bundle formation	GO:0001578	27	0.011
protein localization to organelle	GO:0033365	82	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011	Human
developmental growth	GO:0048589	280	0.011
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.011
negative regulation of gene expression	GO:0010629	387	0.011
regulation of neurogenesis	GO:0050767	158	0.011	Mouse
positive regulation of cellular component organization	GO:0051130	156	0.011
positive regulation of rac gtpase activity	GO:0032855	8	0.011	Human
regulation of gene silencing	GO:0060968	63	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
intracellular signal transduction	GO:0035556	300	0.011	Human Mouse
embryonic organ development	GO:0048568	50	0.010
purine nucleoside catabolic process	GO:0006152	112	0.010	Human Mouse
establishment of protein localization to organelle	GO:0072594	62	0.010
regulation of translation	GO:0006417	56	0.010
regulation of programmed cell death	GO:0043067	152	0.010
purine containing compound catabolic process	GO:0072523	112	0.010	Human Mouse
regulation of catabolic process	GO:0009894	170	0.010	Human Mouse
atp metabolic process	GO:0046034	49	0.010
cellular macromolecular complex assembly	GO:0034622	153	0.010
protein modification process	GO:0036211	438	0.010	Human
dorsal appendage formation	GO:0046843	47	0.010
ribonucleoside metabolic process	GO:0009119	127	0.010	Human Mouse

CG10188 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.035
	nervous system disease	DOID:863	0	0.025

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