Drosophila melanogaster

6 known processes

ttm50 (Dmel_CG2713)

tiny tim 50

(Aliases: i238,Dmel\CG2713,CG2713,i90,Gp99,EG:95B7.3)

ttm50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion organizationGO:0007005650.820
purine nucleoside triphosphate catabolic processGO:00091461080.235
meiotic nuclear divisionGO:00071261510.209
establishment or maintenance of cell polarityGO:00071631670.190
positive regulation of developmental growthGO:0048639620.188
columnar cuboidal epithelial cell developmentGO:00020662490.175
vesicle mediated transportGO:00161923810.170
spindle organizationGO:00070512530.161
single organism biosynthetic processGO:00447112060.154
spermatid developmentGO:0007286980.146
insulin receptor signaling pathwayGO:0008286250.144
regulation of growthGO:00400082330.137
mitotic spindle organizationGO:00070522200.122
growthGO:00400073590.115
lipid biosynthetic processGO:0008610460.113
endocytosisGO:00068973100.111
nuclear divisionGO:00002803320.108
cellular response to dna damage stimulusGO:00069742230.104
organelle fissionGO:00482853400.101
mitotic nuclear divisionGO:00070672130.094
cellular response to chemical stimulusGO:00708871990.088
nucleoside phosphate catabolic processGO:19012921100.088
response to abiotic stimulusGO:00096283410.085
spermatid differentiationGO:00485151140.082
mitotic g2 m transition checkpointGO:0044818700.082
small molecule metabolic processGO:00442813050.082
regulation of developmental growthGO:00486381740.081
purine ribonucleoside metabolic processGO:00461281270.081
cellular protein modification processGO:00064644380.078
nucleoside catabolic processGO:00091641120.074
oxidation reduction processGO:00551141230.074
positive regulation of growthGO:0045927750.064
regulation of chromosome organizationGO:0033044640.061
organic substance transportGO:00717022570.060
positive regulation of cell growthGO:0030307190.060
mitotic sister chromatid segregationGO:0000070870.060
negative regulation of cellular metabolic processGO:00313243820.060
regulation of multicellular organism growthGO:0040014400.059
regulation of insulin receptor signaling pathwayGO:0046626170.055
spindle assembly involved in mitosisGO:0090307500.055
developmental growthGO:00485892800.052
glycosyl compound metabolic processGO:19016571270.051
organonitrogen compound metabolic processGO:19015643180.050
generation of precursor metabolites and energyGO:0006091420.050
nucleobase containing small molecule metabolic processGO:00550861740.050
larval developmentGO:00021641040.050
cell adhesionGO:00071551360.050
purine ribonucleotide catabolic processGO:00091541090.047
regulation of organelle organizationGO:00330431960.047
nucleotide metabolic processGO:00091171610.047
regulation of cellular protein metabolic processGO:00322682430.046
dna metabolic processGO:00062592270.045
carbohydrate derivative metabolic processGO:19011352170.044
cytoplasmic transportGO:00164821300.043
protein secretionGO:0009306450.043
regulation of intracellular signal transductionGO:19025312360.043
negative regulation of epithelial cell proliferationGO:005068040.043
positive regulation of macromolecule metabolic processGO:00106044050.043
ribonucleoside triphosphate catabolic processGO:00092031080.042
lateral inhibitionGO:00463312060.042
negative regulation of signal transductionGO:00099682060.042
sister chromatid segregationGO:0000819920.041
guanosine containing compound metabolic processGO:1901068740.040
lipid homeostasisGO:0055088330.039
purine ribonucleoside catabolic processGO:00461301120.038
chromosome segregationGO:00070591570.038
axonogenesisGO:00074092900.038
steroid biosynthetic processGO:0006694160.038
regulation of mitotic cell cycleGO:00073461900.037
regulation of cell divisionGO:0051302720.037
cellular response to radiationGO:0071478520.037
instar larval developmentGO:0002168550.037
purine nucleoside metabolic processGO:00422781270.037
regulation of mitotic cell cycle phase transitionGO:19019901300.036
multicellular organism growthGO:0035264460.036
cell cycle arrestGO:000705040.036
regulation of nuclear divisionGO:0051783580.036
lipid metabolic processGO:00066291210.036
gtp catabolic processGO:0006184720.036
positive regulation of cellular component organizationGO:00511301560.035
meiotic cell cycleGO:00513211710.035
transcription from rna polymerase ii promoterGO:00063663680.034
response to oxygen containing compoundGO:19017002000.034
nucleotide catabolic processGO:00091661090.034
regulation of protein modification processGO:00313991120.034
meiotic cell cycle processGO:19030461320.033
actin cytoskeleton organizationGO:00300362060.033
small molecule biosynthetic processGO:0044283370.033
wnt signaling pathwayGO:0016055980.033
positive regulation of nitrogen compound metabolic processGO:00511733540.033
gtp metabolic processGO:0046039720.033
regulation of cellular response to insulin stimulusGO:1900076170.032
single organism intracellular transportGO:19025822070.032
cell proliferationGO:00082832990.032
cholesterol homeostasisGO:004263230.032
nucleoside phosphate metabolic processGO:00067531620.032
organophosphate catabolic processGO:00464341120.032
ribose phosphate metabolic processGO:00196931450.031
nucleoside triphosphate metabolic processGO:00091411200.031
tor signalingGO:0031929320.031
cellular response to hormone stimulusGO:0032870440.030
ribonucleoside metabolic processGO:00091191270.030
locomotory behaviorGO:00076261760.030
phagocytosisGO:00069092150.030
positive regulation of developmental processGO:00510941430.029
atp metabolic processGO:0046034490.029
catabolic processGO:00090564090.029
intracellular transportGO:00469072280.028
regulation of cell deathGO:00109411730.028
regulation of cell proliferationGO:00421271630.028
response to woundingGO:0009611940.027
ribonucleotide metabolic processGO:00092591450.027
golgi organizationGO:0007030660.026
purine containing compound catabolic processGO:00725231120.026
response to hormoneGO:0009725450.026
mitotic g2 dna damage checkpointGO:0007095690.026
energy derivation by oxidation of organic compoundsGO:0015980320.026
molting cycleGO:0042303560.026
cell growthGO:00160491080.025
endomembrane system organizationGO:00102561190.024
negative regulation of signalingGO:00230572190.024
response to organic substanceGO:00100332840.024
response to nutrient levelsGO:00316671140.024
cell cycle phase transitionGO:00447701400.024
response to oxygen levelsGO:0070482590.023
regulation of metaphase anaphase transition of cell cycleGO:1902099260.023
positive regulation of multicellular organism growthGO:0040018210.023
negative regulation of transcription dna templatedGO:00458922370.022
negative regulation of cell communicationGO:00106482230.022
regulation of cell growthGO:0001558430.022
single organism catabolic processGO:00447122280.022
positive regulation of nucleic acid templated transcriptionGO:19035082660.022
guanosine containing compound catabolic processGO:1901069740.022
heterocycle catabolic processGO:00467001660.022
regulation of cellular component sizeGO:0032535980.022
g2 dna damage checkpointGO:0031572690.021
molting cycle chitin based cuticleGO:0007591560.021
chemosensory behaviorGO:00076351060.020
negative regulation of rna metabolic processGO:00512532510.020
response to decreased oxygen levelsGO:0036293580.020
purine ribonucleoside triphosphate metabolic processGO:00092051190.020
male gamete generationGO:00482322010.020
regulation of cell cycle processGO:00105641810.019
carbohydrate derivative catabolic processGO:19011361180.019
regulation of cell shapeGO:00083601130.019
purine ribonucleotide metabolic processGO:00091501450.019
asymmetric protein localizationGO:0008105330.019
cell divisionGO:00513012480.019
agingGO:00075681430.019
cellular respirationGO:0045333260.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
protein localizationGO:00081042840.019
organelle fusionGO:0048284460.019
negative regulation of cell cycleGO:00457861160.019
neuromuscular junction developmentGO:00075281490.019
sterol homeostasisGO:005509240.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
membrane organizationGO:00610241120.018
regulation of mitosisGO:0007088560.018
macromolecular complex disassemblyGO:0032984370.018
organic hydroxy compound metabolic processGO:1901615830.018
skin developmentGO:0043588650.018
gene silencingGO:00164581380.018
regulation of behaviorGO:0050795750.018
mitotic cell cycle phase transitionGO:00447721380.018
organonitrogen compound biosynthetic processGO:19015661170.017
regulation of mitochondrion organizationGO:0010821120.017
positive regulation of lipid storageGO:001088440.017
negative regulation of macromolecule biosynthetic processGO:00105582700.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
ribonucleotide catabolic processGO:00092611090.017
negative regulation of growthGO:0045926840.017
response to hypoxiaGO:0001666530.017
nucleoside metabolic processGO:00091161270.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
positive regulation of signalingGO:00230562430.016
regulation of cell sizeGO:0008361630.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
establishment of protein localizationGO:00451841630.016
sex differentiationGO:0007548810.016
spermatogenesisGO:00072832000.016
purine nucleotide catabolic processGO:00061951090.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
regulation of phosphorus metabolic processGO:00511742100.016
rna polyadenylationGO:0043631120.016
epidermal cell differentiationGO:0009913510.015
response to extracellular stimulusGO:00099911160.015
actin filament based processGO:00300292200.015
response to insulinGO:0032868290.015
negative regulation of cellular biosynthetic processGO:00313272770.015
purine nucleotide metabolic processGO:00061631460.015
mitochondrion morphogenesisGO:007058480.015
imaginal disc derived wing morphogenesisGO:00074763370.015
negative regulation of programmed cell deathGO:0043069720.015
axon guidanceGO:00074112330.015
neuron projection guidanceGO:00974852410.015
response to light stimulusGO:00094161240.014
neuronal stem cell divisionGO:0036445350.014
chromosome organizationGO:00512763600.014
establishment of organelle localizationGO:00516561220.014
meiotic chromosome segregationGO:0045132590.014
cellular response to organic substanceGO:00713101320.014
mitotic sister chromatid separationGO:0051306300.014
ribonucleoside catabolic processGO:00424541120.014
intracellular signal transductionGO:00355563000.014
glycosyl compound catabolic processGO:19016581120.014
regulation of mitotic sister chromatid segregationGO:0033047280.014
ribonucleoside biosynthetic processGO:004245530.014
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.014
organonitrogen compound catabolic processGO:19015651280.014
positive regulation of cell deathGO:0010942690.014
organic acid metabolic processGO:00060821030.014
cellular response to insulin stimulusGO:0032869280.013
establishment of localization in cellGO:00516494020.013
chromatin silencingGO:0006342760.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
regulation of sister chromatid segregationGO:0033045280.013
negative regulation of mitotic cell cycleGO:00459301090.013
inorganic ion transmembrane transportGO:0098660730.013
positive regulation of nucleobase containing compound metabolic processGO:00459353320.013
single organism cellular localizationGO:19025801800.013
organophosphate metabolic processGO:00196371950.013
regulation of anatomical structure sizeGO:00900661630.013
protein complex biogenesisGO:00702712010.013
response to biotic stimulusGO:00096072940.012
establishment or maintenance of cytoskeleton polarityGO:0030952440.012
chromosome separationGO:0051304420.012
biological adhesionGO:00226101380.012
regulation of cell cycleGO:00517262910.012
regulation of tor signalingGO:0032006210.012
positive regulation of organelle organizationGO:0010638650.012
deathGO:00162652840.012
gland developmentGO:00487321910.012
regulation of feeding behaviorGO:0060259160.012
glycosyl compound biosynthetic processGO:190165930.012
regulation of chromatin organizationGO:1902275320.012
cellular response to oxygen levelsGO:0071453300.012
positive regulation of protein catabolic processGO:0045732340.012
regulation of notch signaling pathwayGO:00085931000.012
regulation of programmed cell deathGO:00430671520.012
regulation of wnt signaling pathwayGO:0030111680.011
cellular nitrogen compound catabolic processGO:00442701650.011
response to radiationGO:00093141550.011
segmentationGO:00352822070.011
negative regulation of cell deathGO:0060548810.011
regulation of chromosome segregationGO:0051983320.011
programmed cell deathGO:00125012570.011
chromosome condensationGO:0030261410.011
positive regulation of cellular biosynthetic processGO:00313283160.011
mrna polyadenylationGO:0006378110.011
humoral immune responseGO:00069591170.011
developmental maturationGO:00217001720.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
regulation of anatomical structure morphogenesisGO:00226032420.011
protein transportGO:00150311550.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
pharynx developmentGO:006046510.010
cellular response to hypoxiaGO:0071456280.010
metaphase anaphase transition of cell cycleGO:0044784280.010
response to external biotic stimulusGO:00432072930.010
positive regulation of cellular protein catabolic processGO:1903364240.010
multicellular organismal agingGO:00102591400.010

ttm50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.043
cancerDOID:16200.033
organ system cancerDOID:005068600.033
disease of anatomical entityDOID:700.029
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.015
type 2 diabetes mellitusDOID:935200.013
glucose metabolism diseaseDOID:419400.013
acquired metabolic diseaseDOID:006015800.013
diabetes mellitusDOID:935100.013
carbohydrate metabolism diseaseDOID:005001300.013
central nervous system diseaseDOID:33100.012
nervous system diseaseDOID:86300.012