IMP: Integrative Multi-species Prediction

Drosophila melanogaster

59 known processes

pr-set7 (Dmel_CG3307)

CG3307 gene product from transcript CG3307-RC

(Aliases: Pr-set-7,Dmel\CG3307,dSET8,PR-SET7,l(3)neo41,Set7,PR/SET07,dSet8,PR-Set7,CG3307,pr-Set7,Set8)

FLYBASE: FBgn0011474
Entrez: 41743
UniProtKB: Q9VFK6

Process Predictions
Disease Predictions

pr-set7 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromatin silencing	GO:0006342	76	0.990
negative regulation of gene expression	GO:0010629	387	0.980	Human
chromosome organization	GO:0051276	360	0.977
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.976	Human
transcription from rna polymerase ii promoter	GO:0006366	368	0.967	Human
negative regulation of cellular biosynthetic process	GO:0031327	277	0.965	Human
negative regulation of cellular metabolic process	GO:0031324	382	0.964	Human
negative regulation of biosynthetic process	GO:0009890	277	0.958	Human
gene silencing	GO:0016458	138	0.949
negative regulation of rna metabolic process	GO:0051253	251	0.909	Human
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.906	Human
regulation of gene expression epigenetic	GO:0040029	128	0.865
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.858	Human
chromatin organization	GO:0006325	207	0.835
negative regulation of rna biosynthetic process	GO:1902679	240	0.806	Human
cellular protein modification process	GO:0006464	438	0.787
spermatid differentiation	GO:0048515	114	0.774
apoptotic signaling pathway	GO:0097190	27	0.743
negative regulation of gene expression epigenetic	GO:0045814	77	0.733
spindle organization	GO:0007051	253	0.725
negative regulation of transcription dna templated	GO:0045892	237	0.721	Human
autophagy	GO:0006914	108	0.688
covalent chromatin modification	GO:0016569	106	0.685
larval development	GO:0002164	104	0.651	Worm
protein modification process	GO:0036211	438	0.587
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.586	Human
dna metabolic process	GO:0006259	227	0.572
histone h4 acetylation	GO:0043967	13	0.557
chromatin remodeling	GO:0006338	72	0.552
nucleosome mobilization	GO:0042766	9	0.531
embryonic development via the syncytial blastoderm	GO:0001700	148	0.527
positive regulation of macromolecule metabolic process	GO:0010604	405	0.519	Zebrafish
intracellular signal transduction	GO:0035556	300	0.494	Human
cellular response to dna damage stimulus	GO:0006974	223	0.481
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.468	Human
chromosome condensation	GO:0030261	41	0.460
cell division	GO:0051301	248	0.453
maintenance of gastrointestinal epithelium	GO:0030277	3	0.440
gonad development	GO:0008406	50	0.439
cell proliferation	GO:0008283	299	0.439
mitotic spindle organization	GO:0007052	220	0.416
cellular macromolecular complex assembly	GO:0034622	153	0.412
meiotic cell cycle	GO:0051321	171	0.407
nuclear division	GO:0000280	332	0.388
positive regulation of cellular biosynthetic process	GO:0031328	316	0.386
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.380	Human
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.375
male gamete generation	GO:0048232	201	0.367
regulation of neurogenesis	GO:0050767	158	0.351
cell death	GO:0008219	279	0.348	Worm
regulation of intracellular signal transduction	GO:1902531	236	0.348	Human
organelle assembly	GO:0070925	198	0.334
spermatogenesis	GO:0007283	200	0.330
organelle fission	GO:0048285	340	0.326
histone acetylation	GO:0016573	38	0.324
negative regulation of response to stimulus	GO:0048585	258	0.305
regulation of autophagy	GO:0010506	62	0.303
cellular component assembly involved in morphogenesis	GO:0010927	151	0.300
dna conformation change	GO:0071103	105	0.295
mitotic sister chromatid segregation	GO:0000070	87	0.294
heterochromatin organization involved in chromatin silencing	GO:0070868	9	0.290
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.290
sex differentiation	GO:0007548	81	0.289
phosphorylation	GO:0016310	294	0.283
morphogenesis of an epithelium	GO:0002009	276	0.278
histone modification	GO:0016570	106	0.277
peptidyl lysine acetylation	GO:0018394	39	0.273
spermatid development	GO:0007286	98	0.271
rna interference	GO:0016246	27	0.260
meiotic cell cycle process	GO:1903046	132	0.254
positive regulation of programmed cell death	GO:0043068	62	0.247
dna packaging	GO:0006323	91	0.245
regulation of protein transport	GO:0051223	57	0.240
homeostatic process	GO:0042592	199	0.232
nucleosome organization	GO:0034728	59	0.226
nucleosome assembly	GO:0006334	35	0.224
negative regulation of signal transduction	GO:0009968	206	0.222
chromatin modification	GO:0016568	147	0.214
nucleosome positioning	GO:0016584	3	0.205
positive regulation of protein metabolic process	GO:0051247	128	0.203
apoptotic process	GO:0006915	159	0.197	Worm
wnt signaling pathway	GO:0016055	98	0.196
macromolecular complex assembly	GO:0065003	256	0.192
regulation of protein metabolic process	GO:0051246	256	0.187
sister chromatid segregation	GO:0000819	92	0.185
telomere capping	GO:0016233	11	0.179
regulation of mitotic cell cycle	GO:0007346	190	0.178
positive regulation of protein modification process	GO:0031401	58	0.159
development of primary sexual characteristics	GO:0045137	50	0.159
cellular response to organic substance	GO:0071310	132	0.158
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.155
intracellular protein transport	GO:0006886	104	0.154
regulation of chromatin organization	GO:1902275	32	0.152
regulation of cellular catabolic process	GO:0031329	157	0.150
taxis	GO:0042330	304	0.149
determination of adult lifespan	GO:0008340	137	0.149	Worm
chromatin assembly or disassembly	GO:0006333	52	0.140
protein phosphorylation	GO:0006468	169	0.139
cellular response to chemical stimulus	GO:0070887	199	0.135
embryo development ending in birth or egg hatching	GO:0009792	152	0.134	Worm
neuron projection guidance	GO:0097485	241	0.132
regulation of cell cycle process	GO:0010564	181	0.130
regulation of cell differentiation	GO:0045595	302	0.129
multicellular organismal aging	GO:0010259	140	0.128	Worm
proteasomal protein catabolic process	GO:0010498	59	0.125
gliogenesis	GO:0042063	80	0.122
protein modification by small protein conjugation or removal	GO:0070647	106	0.121
protein dna complex subunit organization	GO:0071824	86	0.121
internal protein amino acid acetylation	GO:0006475	38	0.121
histone h3 acetylation	GO:0043966	11	0.119
peptidyl amino acid modification	GO:0018193	105	0.116
negative regulation of cell communication	GO:0010648	223	0.116
regulation of phosphate metabolic process	GO:0019220	210	0.106
programmed cell death	GO:0012501	257	0.106	Worm
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.106
regulation of cell cycle	GO:0051726	291	0.106
body morphogenesis	GO:0010171	2	0.105
signal transduction by phosphorylation	GO:0023014	107	0.105
positive regulation of gene expression	GO:0010628	290	0.103	Zebrafish
olfactory behavior	GO:0042048	97	0.102
modification dependent macromolecule catabolic process	GO:0043632	79	0.102
positive regulation of peptidase activity	GO:0010952	29	0.101
death	GO:0016265	284	0.101	Worm
heterochromatin organization	GO:0070828	25	0.100
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.099
mitotic cell cycle phase transition	GO:0044772	138	0.099
cellular macromolecule localization	GO:0070727	220	0.098
negative regulation of multicellular organismal process	GO:0051241	142	0.097
organonitrogen compound metabolic process	GO:1901564	318	0.096
protein acetylation	GO:0006473	39	0.096
regulation of phosphorylation	GO:0042325	147	0.095
organic acid metabolic process	GO:0006082	103	0.095
growth	GO:0040007	359	0.094
positive regulation of proteolysis	GO:0045862	52	0.092
endocytosis	GO:0006897	310	0.091
catabolic process	GO:0009056	409	0.091
reproductive system development	GO:0061458	74	0.091
regulation of mitosis	GO:0007088	56	0.091
respiratory system development	GO:0060541	213	0.090
regulation of multicellular organismal development	GO:2000026	414	0.089
negative regulation of cell death	GO:0060548	81	0.088
anatomical structure homeostasis	GO:0060249	97	0.088
negative regulation of cell differentiation	GO:0045596	143	0.088
positive regulation of cellular component organization	GO:0051130	156	0.087
positive regulation of molecular function	GO:0044093	136	0.087
nuclear body organization	GO:0030575	6	0.086
regulation of heterochromatin assembly	GO:0031445	8	0.086
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.086
sensory organ morphogenesis	GO:0090596	260	0.085
peptidyl lysine modification	GO:0018205	57	0.085
protein ubiquitination	GO:0016567	70	0.083
response to endogenous stimulus	GO:0009719	119	0.082
cellular catabolic process	GO:0044248	372	0.080
response to alcohol	GO:0097305	95	0.080
regulation of cellular protein metabolic process	GO:0032268	243	0.078
hemocyte differentiation	GO:0042386	38	0.078
eye development	GO:0001654	323	0.078
protein targeting	GO:0006605	64	0.077
gland development	GO:0048732	191	0.077
mitotic nuclear division	GO:0007067	213	0.076
cellular protein catabolic process	GO:0044257	83	0.076
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.076
axonogenesis	GO:0007409	290	0.076
atp dependent chromatin remodeling	GO:0043044	22	0.076
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.075
organic substance transport	GO:0071702	257	0.075
regulation of organelle organization	GO:0033043	196	0.075
chemotaxis	GO:0006935	249	0.074
small molecule metabolic process	GO:0044281	305	0.074
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.073	Human
regulation of chromatin silencing	GO:0031935	36	0.073
mitotic dna damage checkpoint	GO:0044773	74	0.073
posttranscriptional regulation of gene expression	GO:0010608	145	0.073
single organism biosynthetic process	GO:0044711	206	0.071
axon development	GO:0061564	297	0.071
immune response	GO:0006955	246	0.071
meiosis i	GO:0007127	59	0.070
mitotic sister chromatid separation	GO:0051306	30	0.068
cellular response to oxidative stress	GO:0034599	28	0.068
axis specification	GO:0009798	167	0.066
axon guidance	GO:0007411	233	0.066
histone lysine demethylation	GO:0070076	6	0.065
positive regulation of endopeptidase activity	GO:0010950	26	0.065
regulation of protein import into nucleus	GO:0042306	28	0.065
sister chromatid cohesion	GO:0007062	18	0.065
reproductive structure development	GO:0048608	74	0.065
negative regulation of neurogenesis	GO:0050768	53	0.065
response to ionizing radiation	GO:0010212	32	0.064
protein localization to nucleus	GO:0034504	55	0.064
chromosome separation	GO:0051304	42	0.064
internal peptidyl lysine acetylation	GO:0018393	38	0.063
response to nitrogen compound	GO:1901698	90	0.062
cell fate specification	GO:0001708	71	0.061
regulation of apoptotic process	GO:0042981	130	0.061
imaginal disc growth	GO:0007446	37	0.061
regulation of chromatin modification	GO:1903308	28	0.061
developmental programmed cell death	GO:0010623	138	0.061
response to external biotic stimulus	GO:0043207	293	0.060
cellular protein localization	GO:0034613	160	0.060
response to oxygen containing compound	GO:1901700	200	0.059
single organism nuclear import	GO:1902593	51	0.059
cellular response to abiotic stimulus	GO:0071214	58	0.057
regulation of protein modification process	GO:0031399	112	0.057
cellular amino acid metabolic process	GO:0006520	61	0.057
response to organic substance	GO:0010033	284	0.056
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.056
positive regulation of cellular protein metabolic process	GO:0032270	118	0.056
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.056
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.056
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.056
negative regulation of protein processing	GO:0010955	31	0.055
regulation of cytoplasmic transport	GO:1903649	47	0.055
regulation of gene silencing	GO:0060968	63	0.054
intrinsic apoptotic signaling pathway	GO:0097193	16	0.054
eye photoreceptor cell differentiation	GO:0001754	145	0.054
regulation of transferase activity	GO:0051338	58	0.054
protein modification by small protein conjugation	GO:0032446	79	0.054
regulation of nucleocytoplasmic transport	GO:0046822	35	0.053
cuticle development	GO:0042335	86	0.053
response to organic cyclic compound	GO:0014070	89	0.053
connective tissue development	GO:0061448	3	0.053
instar larval development	GO:0002168	55	0.052
developmental growth	GO:0048589	280	0.052
mesenchymal cell development	GO:0014031	1	0.052
positive regulation of phosphate metabolic process	GO:0045937	139	0.052
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.052
peptidyl lysine methylation	GO:0018022	16	0.052
regulation of proteolysis	GO:0030162	87	0.052
chromosome segregation	GO:0007059	157	0.050
regulation of transcription by chromatin organization	GO:0034401	3	0.049
regulation of chromosome organization	GO:0033044	64	0.049
purine nucleotide metabolic process	GO:0006163	146	0.049
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	11	0.049
regulation of cell development	GO:0060284	215	0.048
dna repair	GO:0006281	54	0.048
negative regulation of phosphorylation	GO:0042326	35	0.047
organic substance catabolic process	GO:1901575	308	0.047
chromatin mediated maintenance of transcription	GO:0048096	7	0.046
regulation of dna metabolic process	GO:0051052	34	0.046
regulation of response to extracellular stimulus	GO:0032104	18	0.046
protein complex biogenesis	GO:0070271	201	0.046
proteolysis	GO:0006508	192	0.045
regulation of catabolic process	GO:0009894	170	0.045
neuron maturation	GO:0042551	31	0.045
positive regulation of catalytic activity	GO:0043085	118	0.045
regulation of glial cell proliferation	GO:0060251	11	0.044
salivary gland cell autophagic cell death	GO:0035071	83	0.043
regulation of catalytic activity	GO:0050790	185	0.043
positive regulation of protein import into nucleus	GO:0042307	21	0.043
protein targeting to nucleus	GO:0044744	51	0.043
regulation of intracellular protein transport	GO:0033157	46	0.042
dendrite morphogenesis	GO:0048813	199	0.042
mapk cascade	GO:0000165	107	0.042
regulation of protein deacetylation	GO:0090311	2	0.042
nitrogen compound transport	GO:0071705	85	0.041
protein acylation	GO:0043543	42	0.041
protein transport	GO:0015031	155	0.041
nuclear import	GO:0051170	51	0.040
lateral inhibition	GO:0046331	206	0.039
regulation of response to external stimulus	GO:0032101	115	0.039
dorsal closure	GO:0007391	79	0.038
protein localization to organelle	GO:0033365	82	0.038
posttranscriptional gene silencing by rna	GO:0035194	45	0.038
nucleotide metabolic process	GO:0009117	161	0.038
histone h4 k16 acetylation	GO:0043984	4	0.038
mrna processing	GO:0006397	104	0.037
hemopoiesis	GO:0030097	46	0.037
positive regulation of rna metabolic process	GO:0051254	271	0.037
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.037
negative regulation of cell cycle	GO:0045786	116	0.037
extrinsic apoptotic signaling pathway	GO:0097191	1	0.037
regulation of neuron differentiation	GO:0045664	103	0.036
regulation of mapk cascade	GO:0043408	92	0.036
negative regulation of cell cycle process	GO:0010948	109	0.036
regulation of protein localization to nucleus	GO:1900180	29	0.036
cell cycle checkpoint	GO:0000075	95	0.036
posttranscriptional gene silencing	GO:0016441	46	0.036
modification dependent protein catabolic process	GO:0019941	78	0.036
positive regulation of chromatin silencing	GO:0031937	16	0.036
positive regulation of intracellular signal transduction	GO:1902533	116	0.035
regionalization	GO:0003002	416	0.035	Zebrafish
response to uv	GO:0009411	24	0.035
response to organonitrogen compound	GO:0010243	75	0.035
centrosome organization	GO:0051297	163	0.035
meiotic nuclear division	GO:0007126	151	0.035
regulation of programmed cell death	GO:0043067	152	0.035
erk1 and erk2 cascade	GO:0070371	39	0.035
anterior posterior pattern specification	GO:0009952	136	0.034
cellular response to organonitrogen compound	GO:0071417	36	0.034
regulation of hemocyte differentiation	GO:0045610	22	0.034
response to extracellular stimulus	GO:0009991	116	0.034
negative regulation of neuroblast proliferation	GO:0007406	27	0.034
regulation of cellular response to stress	GO:0080135	89	0.034	Human
multicellular organism growth	GO:0035264	46	0.033
nuclear transport	GO:0051169	72	0.033
head development	GO:0060322	135	0.033
protein complex assembly	GO:0006461	200	0.032
regulation of response to dna damage stimulus	GO:2001020	23	0.032	Human
positive regulation of phosphorylation	GO:0042327	87	0.032
mitotic cell cycle embryonic	GO:0045448	38	0.032
positive regulation of biosynthetic process	GO:0009891	316	0.032
open tracheal system development	GO:0007424	204	0.031
positive regulation of organelle organization	GO:0010638	65	0.031
cytoplasmic transport	GO:0016482	130	0.031
response to other organism	GO:0051707	293	0.030
regulation of nervous system development	GO:0051960	248	0.030
response to bacterium	GO:0009617	198	0.030
response to transforming growth factor beta	GO:0071559	18	0.030
response to biotic stimulus	GO:0009607	294	0.030
negative regulation of developmental process	GO:0051093	201	0.030
exocrine system development	GO:0035272	162	0.030
sensory perception of mechanical stimulus	GO:0050954	72	0.030
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.030
muscle structure development	GO:0061061	224	0.030
negative regulation of apoptotic process	GO:0043066	63	0.029
regulation of histone modification	GO:0031056	20	0.029
morphogenesis of follicular epithelium	GO:0016333	36	0.029
positive regulation of signal transduction	GO:0009967	223	0.029
single organism cellular localization	GO:1902580	180	0.028
tissue morphogenesis	GO:0048729	297	0.028
intracellular transport	GO:0046907	228	0.028
mitotic cell cycle checkpoint	GO:0007093	88	0.027
positive regulation of multicellular organismal process	GO:0051240	143	0.027
negative regulation of cell cycle phase transition	GO:1901988	103	0.027
protein import into nucleus	GO:0006606	51	0.027
regulation of phosphatase activity	GO:0010921	3	0.027
i kappab phosphorylation	GO:0007252	3	0.027
epithelial cell development	GO:0002064	274	0.027
response to sterol	GO:0036314	34	0.027
regulation of cell death	GO:0010941	173	0.027
immune system process	GO:0002376	347	0.026
purine ribonucleoside metabolic process	GO:0046128	127	0.026
tissue death	GO:0016271	102	0.026
organophosphate metabolic process	GO:0019637	195	0.026
cellular component disassembly	GO:0022411	46	0.026
dna integrity checkpoint	GO:0031570	81	0.025
cellular response to oxygen containing compound	GO:1901701	79	0.025
regulation of wnt signaling pathway	GO:0030111	68	0.025
carbohydrate derivative metabolic process	GO:1901135	217	0.025
glycerolipid metabolic process	GO:0046486	34	0.025
regulation of immune system process	GO:0002682	176	0.025
salivary gland morphogenesis	GO:0007435	145	0.025
positive regulation of transcription dna templated	GO:0045893	266	0.025
stem cell division	GO:0017145	69	0.025
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.025
male meiosis	GO:0007140	52	0.024
negative regulation of programmed cell death	GO:0043069	72	0.024
regulation of photoreceptor cell differentiation	GO:0046532	34	0.024
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.024
regulation of cell cycle phase transition	GO:1901987	130	0.024
response to radiation	GO:0009314	155	0.024
regulation of establishment of protein localization	GO:0070201	61	0.024
cell cycle dna replication	GO:0044786	23	0.024
phagocytosis	GO:0006909	215	0.024
epithelial cell differentiation	GO:0030855	322	0.024
histone exchange	GO:0043486	21	0.024
hematopoietic or lymphoid organ development	GO:0048534	57	0.023
establishment of protein localization	GO:0045184	163	0.023
gene silencing by rna	GO:0031047	57	0.023
negative regulation of proteolysis	GO:0045861	31	0.023
negative regulation of cellular protein metabolic process	GO:0032269	85	0.023
positive regulation of cell death	GO:0010942	69	0.023
regulation of proteasomal protein catabolic process	GO:0061136	39	0.023
intracellular steroid hormone receptor signaling pathway	GO:0030518	12	0.023
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	26	0.023
positive regulation of developmental process	GO:0051094	143	0.023
dna replication checkpoint	GO:0000076	8	0.022
establishment of protein localization to organelle	GO:0072594	62	0.022
negative regulation of intracellular signal transduction	GO:1902532	57	0.022
muscle organ development	GO:0007517	127	0.022
response to ketone	GO:1901654	34	0.022
positive regulation of cellular component biogenesis	GO:0044089	80	0.022
cellular response to endogenous stimulus	GO:0071495	80	0.022
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.021
ribonucleoprotein complex assembly	GO:0022618	23	0.021
protein processing	GO:0016485	68	0.021
positive regulation of cellular catabolic process	GO:0031331	95	0.021
eggshell chorion gene amplification	GO:0007307	9	0.021
atp metabolic process	GO:0046034	49	0.021
autophagic cell death	GO:0048102	83	0.021
eye morphogenesis	GO:0048592	260	0.021
wing disc morphogenesis	GO:0007472	344	0.021
negative regulation of protein catabolic process	GO:0042177	17	0.021
striated muscle cell differentiation	GO:0051146	90	0.020
positive regulation of phosphorus metabolic process	GO:0010562	139	0.020
actin filament organization	GO:0007015	126	0.020
lipid metabolic process	GO:0006629	121	0.020
negative regulation of nervous system development	GO:0051961	92	0.020
histone h3 k4 methylation	GO:0051568	16	0.020
aromatic compound catabolic process	GO:0019439	166	0.020
negative regulation of cell proliferation	GO:0008285	69	0.020
germ line stem cell division	GO:0042078	25	0.020
positive regulation of protein localization to nucleus	GO:1900182	21	0.020
dendrite development	GO:0016358	204	0.020
aging	GO:0007568	143	0.020	Worm
cellular macromolecule catabolic process	GO:0044265	136	0.020
peptide metabolic process	GO:0006518	80	0.020
vesicle mediated transport	GO:0016192	381	0.019
regulation of intracellular transport	GO:0032386	64	0.019
positive regulation of rna biosynthetic process	GO:1902680	266	0.019
negative regulation of protein modification process	GO:0031400	29	0.019
ribonucleotide metabolic process	GO:0009259	145	0.019
negative regulation of protein phosphorylation	GO:0001933	17	0.019
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.019
cellular homeostasis	GO:0019725	80	0.019
regulation of sister chromatid cohesion	GO:0007063	2	0.019
glycosyl compound metabolic process	GO:1901657	127	0.019
dna amplification	GO:0006277	11	0.019
negative regulation of cellular catabolic process	GO:0031330	34	0.019
dna biosynthetic process	GO:0071897	24	0.018
dna methylation or demethylation	GO:0044728	4	0.018
regulation of cellular amide metabolic process	GO:0034248	39	0.018
positive regulation of stem cell differentiation	GO:2000738	3	0.018
positive regulation of cell development	GO:0010720	61	0.018
regulation of cell division	GO:0051302	72	0.018
compound eye morphogenesis	GO:0001745	249	0.018
protein autophosphorylation	GO:0046777	15	0.018
cytokinesis	GO:0000910	90	0.018
response to oxidative stress	GO:0006979	86	0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.018
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	9	0.018
regulation of hydrolase activity	GO:0051336	97	0.018
histone h3 k27 methylation	GO:0070734	6	0.018
histone h4 k12 acetylation	GO:0043983	2	0.018
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.018
positive regulation of mapk cascade	GO:0043410	63	0.017
glial cell differentiation	GO:0010001	35	0.017
positive regulation of cell cycle process	GO:0090068	28	0.017
cellular response to lipid	GO:0071396	20	0.017
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.017
metaphase anaphase transition of cell cycle	GO:0044784	28	0.017
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.017
embryonic organ development	GO:0048568	50	0.017
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.017
regulation of anatomical structure morphogenesis	GO:0022603	242	0.017
regulation of multi organism process	GO:0043900	131	0.017
regulation of chromatin binding	GO:0035561	3	0.017
defense response	GO:0006952	300	0.017
purine ribonucleotide catabolic process	GO:0009154	109	0.017
regulation of muscle cell differentiation	GO:0051147	8	0.017
positive regulation of transport	GO:0051050	92	0.017
protein maturation	GO:0051604	71	0.017
signal transduction in response to dna damage	GO:0042770	3	0.017	Human
negative regulation of mitotic cell cycle	GO:0045930	109	0.017
protein dna complex assembly	GO:0065004	63	0.017
ribonucleoprotein complex subunit organization	GO:0071826	28	0.017
cellular ketone metabolic process	GO:0042180	24	0.017
innate immune response	GO:0045087	144	0.016
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	6	0.016
regulation of protein localization	GO:0032880	76	0.016
nucleobase containing compound catabolic process	GO:0034655	165	0.016
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.016
regulation of protein ubiquitination	GO:0031396	22	0.016
positive regulation of autophagy	GO:0010508	21	0.016
nucleoside monophosphate metabolic process	GO:0009123	52	0.016
neuron remodeling	GO:0016322	29	0.016
chromosome organization involved in meiosis	GO:0070192	10	0.016
methylation	GO:0032259	47	0.016
regulation of growth	GO:0040008	233	0.016
camera type eye development	GO:0043010	4	0.016
stem cell differentiation	GO:0048863	117	0.016
regulation of cell proliferation	GO:0042127	163	0.016
positive regulation of histone deacetylation	GO:0031065	2	0.016
response to lipid	GO:0033993	38	0.016
cellular response to starvation	GO:0009267	61	0.015
regulation of mitotic sister chromatid separation	GO:0010965	28	0.015
salivary gland development	GO:0007431	162	0.015
positive regulation of neurogenesis	GO:0050769	41	0.015
heterocycle catabolic process	GO:0046700	166	0.015
mitotic spindle elongation	GO:0000022	81	0.015
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	16	0.015
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.015
forebrain development	GO:0030900	2	0.015
regulation of organ growth	GO:0046620	42	0.015
ubiquitin dependent protein catabolic process	GO:0006511	78	0.015
long term memory	GO:0007616	62	0.015
positive regulation of transferase activity	GO:0051347	26	0.014
regulation of nuclear division	GO:0051783	58	0.014
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.014
cellular protein complex assembly	GO:0043623	71	0.014
purine containing compound catabolic process	GO:0072523	112	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
regulation of notch signaling pathway	GO:0008593	100	0.014
organophosphate catabolic process	GO:0046434	112	0.014
positive regulation of nervous system development	GO:0051962	69	0.014
sensory organ precursor cell division	GO:0045035	10	0.014
positive regulation of cell communication	GO:0010647	250	0.014
response to wounding	GO:0009611	94	0.014
induction of programmed cell death by hormones	GO:0035081	12	0.014
sarcomere organization	GO:0045214	26	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.014
neural precursor cell proliferation	GO:0061351	75	0.014
nucleoside metabolic process	GO:0009116	127	0.013

pr-set7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.052
cancer	DOID:162	0.052
organ system cancer	DOID:0050686	0.052

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