Drosophila melanogaster

45 known processes

Calx (Dmel_CG5685)

Na/Ca-exchange protein

(Aliases: CALX,CalX,Dmel\CG5685,Dmel/Ncx,9C5,Ncx,NCX,calX,CG5685,anon-93ABa,calx,CALX1.1)

Calx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to light stimulusGO:0071482370.306
cellular response to radiationGO:0071478520.295
response to abiotic stimulusGO:00096283410.281
response to radiationGO:00093141550.266
detection of light stimulusGO:0009583580.216
regulation of localizationGO:00328792750.170
establishment of localization in cellGO:00516494020.144
detection of visible lightGO:0009584380.120
single organism biosynthetic processGO:00447112060.115
g protein coupled receptor signaling pathwayGO:00071861360.112
phosphorylationGO:00163102940.110
regulation of multicellular organismal developmentGO:20000264140.110
intracellular signal transductionGO:00355563000.103
detection of abiotic stimulusGO:0009582660.101
photoreceptor cell differentiationGO:00465301700.098
compound eye photoreceptor developmentGO:0042051780.098
regulation of cell developmentGO:00602842150.096
response to temperature stimulusGO:00092661060.092
programmed cell deathGO:00125012570.088
phototransductionGO:0007602520.084
synaptic transmissionGO:00072682880.083
positive regulation of macromolecule metabolic processGO:00106044050.082
detection of stimulusGO:00516061560.082
regulation of phosphate metabolic processGO:00192202100.079
organonitrogen compound metabolic processGO:19015643180.076
small molecule metabolic processGO:00442813050.076
positive regulation of nucleobase containing compound metabolic processGO:00459353320.076
cellular protein modification processGO:00064644380.075
deactivation of rhodopsin mediated signalingGO:0016059170.072
organophosphate metabolic processGO:00196371950.070
nucleotide metabolic processGO:00091171610.068
catabolic processGO:00090564090.066
learningGO:0007612750.065
carbohydrate derivative metabolic processGO:19011352170.062
ion transportGO:00068111450.062
positive regulation of nitrogen compound metabolic processGO:00511733540.061
eye developmentGO:00016543230.061
protein modification processGO:00362114380.060
single organism catabolic processGO:00447122280.059
neurological system processGO:00508773580.058
regulation of transportGO:00510491810.058
cellular response to chemical stimulusGO:00708871990.057
organic acid metabolic processGO:00060821030.056
regulation of rhodopsin mediated signaling pathwayGO:0022400170.055
regulation of intracellular signal transductionGO:19025312360.054
nucleoside phosphate metabolic processGO:00067531620.054
protein localizationGO:00081042840.054
organic substance catabolic processGO:19015753080.051
regulation of cellular response to stressGO:0080135890.050
regulation of cellular ketone metabolic processGO:001056530.050
response to light stimulusGO:00094161240.050
detection of external stimulusGO:0009581660.049
single organism behaviorGO:00447083910.048
regulation of cell differentiationGO:00455953020.048
learning or memoryGO:00076111410.048
central nervous system developmentGO:00074172010.048
purine containing compound metabolic processGO:00725211550.047
purine nucleotide metabolic processGO:00061631460.047
endocytosisGO:00068973100.046
carboxylic acid metabolic processGO:0019752920.046
secretion by cellGO:00329401010.046
nucleoside phosphate catabolic processGO:19012921100.046
regulation of phosphorus metabolic processGO:00511742100.045
negative regulation of signalingGO:00230572190.045
neurotransmitter secretionGO:0007269350.045
synapse organizationGO:00508081960.045
transcription from rna polymerase ii promoterGO:00063663680.044
imaginal disc derived appendage morphogenesisGO:00351143950.044
purine ribonucleotide metabolic processGO:00091501450.043
cell deathGO:00082192790.043
sensory organ morphogenesisGO:00905962600.043
appendage developmentGO:00487364010.043
eye morphogenesisGO:00485922600.043
regulation of cellular component biogenesisGO:00440872010.043
deathGO:00162652840.043
regulation of neurogenesisGO:00507671580.043
growthGO:00400073590.043
positive regulation of biosynthetic processGO:00098913160.043
organic substance transportGO:00717022570.042
cellular catabolic processGO:00442483720.042
rhythmic processGO:00485111060.042
detection of stimulus involved in sensory perceptionGO:0050906920.041
response to starvationGO:0042594970.041
signal releaseGO:0023061490.041
regulation of purine nucleotide metabolic processGO:1900542620.041
positive regulation of cellular biosynthetic processGO:00313283160.041
secretionGO:00469031090.041
photoreceptor cell developmentGO:0042461960.040
sensory perceptionGO:00076001960.040
phototransduction visible lightGO:0007603270.040
peptidyl threonine phosphorylationGO:001810720.040
imaginal disc derived appendage developmentGO:00487373990.040
appendage morphogenesisGO:00351073970.040
rhodopsin mediated signaling pathwayGO:0016056210.039
cellular response to abiotic stimulusGO:0071214580.039
negative regulation of response to stimulusGO:00485852580.039
negative regulation of rna metabolic processGO:00512532510.039
establishment of organelle localizationGO:00516561220.038
neurotransmitter transportGO:0006836370.038
response to purine containing compoundGO:0014074120.038
regulation of programmed cell deathGO:00430671520.037
locomotory behaviorGO:00076261760.037
response to organophosphorusGO:004668320.037
negative regulation of cellular biosynthetic processGO:00313272770.037
eye photoreceptor cell developmentGO:0042462810.037
wing disc morphogenesisGO:00074723440.037
positive regulation of catabolic processGO:00098961050.036
vesicle mediated transportGO:00161923810.036
negative regulation of nitrogen compound metabolic processGO:00511722650.036
response to monosaccharideGO:003428440.036
positive regulation of phosphate metabolic processGO:00459371390.036
purine nucleoside catabolic processGO:00061521120.036
negative regulation of gene expressionGO:00106293870.036
ribonucleotide metabolic processGO:00092591450.036
negative regulation of signal transductionGO:00099682060.035
kidney developmentGO:000182230.035
compound eye developmentGO:00487493070.035
negative regulation of multicellular organismal processGO:00512411420.035
signal transduction by phosphorylationGO:00230141070.035
oxoacid metabolic processGO:00434361030.035
cellular response to extracellular stimulusGO:0031668640.035
purine nucleoside metabolic processGO:00422781270.035
negative regulation of cell communicationGO:00106482230.034
intracellular transportGO:00469072280.034
positive regulation of signalingGO:00230562430.034
nucleobase containing small molecule metabolic processGO:00550861740.034
mapk cascadeGO:00001651070.034
response to organonitrogen compoundGO:0010243750.034
body morphogenesisGO:001017120.034
taxisGO:00423303040.034
regulation of catalytic activityGO:00507901850.033
regulation of cellular localizationGO:00603411360.033
negative regulation of nucleobase containing compound metabolic processGO:00459342610.033
forebrain developmentGO:003090020.032
negative regulation of cellular metabolic processGO:00313243820.032
positive regulation of cell communicationGO:00106472500.031
camera type eye developmentGO:004301040.031
protein phosphorylationGO:00064681690.031
response to endogenous stimulusGO:00097191190.031
compound eye morphogenesisGO:00017452490.031
localization of cellGO:00516742570.031
regulation of secretion by cellGO:1903530390.030
regulation of g protein coupled receptor protein signaling pathwayGO:0008277230.030
regulation of cell deathGO:00109411730.029
cellular amine metabolic processGO:0044106120.029
regulation of response to stressGO:00801342000.029
compound eye photoreceptor cell differentiationGO:00017511400.029
regulation of secretionGO:0051046440.029
cell motilityGO:00488702510.029
eye photoreceptor cell differentiationGO:00017541450.029
regulation of phosphorylationGO:00423251470.028
cellular nitrogen compound catabolic processGO:00442701650.028
response to organic substanceGO:00100332840.028
regulation of synapse structure and activityGO:00508031280.028
regulation of molecular functionGO:00650092170.028
response to hexoseGO:000974630.028
macromolecule catabolic processGO:00090571610.027
response to nutrient levelsGO:00316671140.027
regulation of embryonic pattern specificationGO:1902875270.027
positive regulation of phosphorus metabolic processGO:00105621390.027
positive regulation of transportGO:0051050920.027
metal ion transportGO:0030001740.027
regulation of ion transportGO:0043269390.027
regulation of growthGO:00400082330.027
regulation of cell cycleGO:00517262910.027
organic cyclic compound catabolic processGO:19013611680.026
organophosphate catabolic processGO:00464341120.026
ribose phosphate metabolic processGO:00196931450.026
homeostatic processGO:00425921990.026
positive regulation of cellular component organizationGO:00511301560.026
aromatic compound catabolic processGO:00194391660.026
actin filament based processGO:00300292200.026
neuromuscular junction developmentGO:00075281490.026
developmental growthGO:00485892800.026
lipid metabolic processGO:00066291210.026
positive regulation of catalytic activityGO:00430851180.026
rna localizationGO:00064031150.026
neutral lipid biosynthetic processGO:004646020.026
purine ribonucleoside triphosphate catabolic processGO:00092071080.026
regulation of cellular catabolic processGO:00313291570.026
photoreceptor cell maintenanceGO:0045494110.025
ras protein signal transductionGO:0007265880.025
negative regulation of transcription dna templatedGO:00458922370.025
ribonucleoside catabolic processGO:00424541120.025
proteolysisGO:00065081920.025
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.024
positive regulation of multicellular organismal processGO:00512401430.024
regulation of mapk cascadeGO:0043408920.024
cell migrationGO:00164772380.024
imaginal disc derived wing morphogenesisGO:00074763370.024
glycosyl compound metabolic processGO:19016571270.024
negative regulation of developmental processGO:00510932010.024
tube morphogenesisGO:00352391910.024
regulation of organ morphogenesisGO:2000027780.024
transmembrane transportGO:00550851390.024
purine containing compound catabolic processGO:00725231120.023
oocyte differentiationGO:00099941450.023
purine ribonucleoside metabolic processGO:00461281270.023
glycosyl compound catabolic processGO:19016581120.023
positive regulation of nucleotide metabolic processGO:0045981550.023
regulation of cellular amine metabolic processGO:003323830.023
telencephalon developmentGO:002153720.023
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.023
response to glucoseGO:000974920.023
protein transportGO:00150311550.023
actin cytoskeleton organizationGO:00300362060.022
determination of adult lifespanGO:00083401370.022
nucleoside catabolic processGO:00091641120.022
cation transportGO:00068121100.022
negative regulation of cell differentiationGO:00455961430.022
positive regulation of gene expressionGO:00106282900.022
positive regulation of purine nucleotide metabolic processGO:1900544550.022
phagocytosisGO:00069092150.022
cellular response to ethanolGO:007136140.022
post embryonic appendage morphogenesisGO:00351203850.022
organonitrogen compound catabolic processGO:19015651280.022
establishment of planar polarityGO:0001736870.022
regulation of organelle organizationGO:00330431960.022
chemotaxisGO:00069352490.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
regulation of cellular amino acid metabolic processGO:000652100.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
nitrogen compound transportGO:0071705850.021
ribonucleotide catabolic processGO:00092611090.021
chromosome organizationGO:00512763600.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
nucleoside triphosphate catabolic processGO:00091431080.021
macromolecular complex assemblyGO:00650032560.021
thermotaxisGO:0043052160.021
purine nucleotide catabolic processGO:00061951090.021
positive regulation of calcium ion transportGO:005192840.021
negative regulation of biosynthetic processGO:00098902770.021
cognitionGO:00508901410.021
establishment of protein localizationGO:00451841630.020
response to extracellular stimulusGO:00099911160.020
positive regulation of cellular catabolic processGO:0031331950.020
purine nucleoside triphosphate metabolic processGO:00091441190.020
organelle assemblyGO:00709251980.020
regulation of protein metabolic processGO:00512462560.020
negative regulation of cellular component organizationGO:00511291080.020
single organism intracellular transportGO:19025822070.020
ribonucleoside metabolic processGO:00091191270.020
peptidyl amino acid modificationGO:00181931050.020
developmental maturationGO:00217001720.019
regulation of neuron differentiationGO:00456641030.019
olfactory learningGO:0008355560.019
nucleoside metabolic processGO:00091161270.019
purine ribonucleoside catabolic processGO:00461301120.019
anatomical structure homeostasisGO:0060249970.019
neuromuscular synaptic transmissionGO:0007274670.019
protein maturationGO:0051604710.019
apoptotic processGO:00069151590.018
cellular ketone metabolic processGO:0042180240.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
lipid biosynthetic processGO:0008610460.018
positive regulation of response to stimulusGO:00485843230.018
small gtpase mediated signal transductionGO:0007264880.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
regulation of response to external stimulusGO:00321011150.018
regulation of cell projection organizationGO:0031344920.018
cellular lipid metabolic processGO:0044255830.018
protein complex biogenesisGO:00702712010.018
regulation of synaptic transmissionGO:0050804690.018
tissue migrationGO:00901301550.018
protein catabolic processGO:00301631010.018
negative regulation of growthGO:0045926840.018
positive regulation of cellular amine metabolic processGO:003324000.018
response to heatGO:0009408630.018
organelle localizationGO:00516401480.018
nucleotide catabolic processGO:00091661090.018
amine metabolic processGO:0009308120.018
cation transmembrane transportGO:0098655880.018
protein modification by small protein conjugationGO:0032446790.018
response to lipopolysaccharideGO:003249640.017
regulation of sequestering of calcium ionGO:005128230.017
regulation of nucleotide metabolic processGO:0006140620.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
cellular amino acid metabolic processGO:0006520610.017
circadian behaviorGO:0048512760.017
chaeta developmentGO:0022416970.017
adult behaviorGO:00305341370.017
cellular response to starvationGO:0009267610.017
protein modification by small protein conjugation or removalGO:00706471060.017
regulation of catabolic processGO:00098941700.017
regulation of epithelial cell differentiationGO:003085640.017
response to decreased oxygen levelsGO:0036293580.017
regulation of hydrolase activityGO:0051336970.017
regulation of reproductive processGO:2000241540.017
cellular protein localizationGO:00346131600.017
positive regulation of transcription dna templatedGO:00458932660.017
limb developmentGO:006017310.017
cellular macromolecule catabolic processGO:00442651360.017
morphogenesis of a polarized epitheliumGO:0001738930.016
gliogenesisGO:0042063800.016
pigment metabolic processGO:0042440840.016
rna processingGO:00063961470.016
associative learningGO:0008306650.016
positive regulation of molecular functionGO:00440931360.016
regulation of apoptotic processGO:00429811300.016
regulation of notch signaling pathwayGO:00085931000.016
gtp metabolic processGO:0046039720.016
regulation of proteolysisGO:0030162870.016
regulation of cellular protein metabolic processGO:00322682430.016
intracellular protein transportGO:00068861040.016
camera type eye morphogenesisGO:004859320.015
regulation of nervous system developmentGO:00519602480.015
cellular response to uvGO:0034644120.015
positive regulation of rna metabolic processGO:00512542710.015
regulation of nucleotide catabolic processGO:0030811480.015
axon developmentGO:00615642970.015
positive regulation of signal transductionGO:00099672230.015
cellular response to organic substanceGO:00713101320.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regulation of neuron projection developmentGO:0010975690.015
sensory perception of painGO:001923340.015
circadian rhythmGO:00076231050.015
response to oxygen levelsGO:0070482590.015
synaptic growth at neuromuscular junctionGO:00511241190.015
detection of chemical stimulus involved in sensory perception of tasteGO:0050912130.015
multi multicellular organism processGO:00447061230.015
urogenital system developmentGO:0001655720.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
response to oxygen containing compoundGO:19017002000.015
cyclic purine nucleotide metabolic processGO:0052652250.015
rhabdomere developmentGO:0042052380.014
regulation of embryonic developmentGO:0045995680.014
cellular component assembly involved in morphogenesisGO:00109271510.014
negative regulation of phosphorus metabolic processGO:0010563450.014
hindbrain developmentGO:003090220.014
regulation of protein localizationGO:0032880760.014
behavioral response to ethanolGO:0048149490.014
positive regulation of cell motilityGO:200014730.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
ion transmembrane transportGO:00342201220.014
mitotic nuclear divisionGO:00070672130.014
regulation of neurotransmitter secretionGO:0046928140.014
positive regulation of rna biosynthetic processGO:19026802660.014
positive regulation of synaptic transmissionGO:0050806150.014
heterocycle catabolic processGO:00467001660.014
locomotor rhythmGO:0045475560.014
negative regulation of protein metabolic processGO:0051248850.014
negative regulation of homeostatic processGO:003284520.014
positive regulation of phosphorylationGO:0042327870.014
mitochondrion organizationGO:0007005650.014
notch signaling pathwayGO:00072191200.014
peptidyl threonine modificationGO:001821030.014
establishment of tissue polarityGO:0007164870.014
camp biosynthetic processGO:0006171170.014
developmental programmed cell deathGO:00106231380.014
carbohydrate derivative catabolic processGO:19011361180.013
multicellular organismal agingGO:00102591400.013
epithelial cell developmentGO:00020642740.013
protein ubiquitinationGO:0016567700.013
negative regulation of cell developmentGO:0010721620.013
eye pigment metabolic processGO:0042441330.013
response to hypoxiaGO:0001666530.013
nuclear divisionGO:00002803320.013
organophosphate biosynthetic processGO:0090407460.013
single organism cellular localizationGO:19025801800.013
negative regulation of nervous system developmentGO:0051961920.013
regulation of neurotransmitter transportGO:0051588140.013
response to organic cyclic compoundGO:0014070890.013
response to oxidative stressGO:0006979860.013
regulation of protein modification processGO:00313991120.013
positive regulation of programmed cell deathGO:0043068620.013
cellular response to biotic stimulusGO:007121640.013
metal ion homeostasisGO:0055065440.013
vitamin biosynthetic processGO:000911010.013
establishment of rna localizationGO:0051236470.013
wnt signaling pathwayGO:0016055980.013
stress activated mapk cascadeGO:0051403520.013
positive regulation of hydrolase activityGO:0051345780.013
positive regulation of intracellular signal transductionGO:19025331160.013
axon guidanceGO:00074112330.013
purine ribonucleotide catabolic processGO:00091541090.013
cellular macromolecule localizationGO:00707272200.013
agingGO:00075681430.013
calcium ion transportGO:0006816240.013
fat soluble vitamin biosynthetic processGO:004236210.013
regulation of developmental growthGO:00486381740.013
epithelial cell differentiationGO:00308553220.013
positive regulation of cell migrationGO:003033520.013
regulation of neurotransmitter levelsGO:0001505380.013
negative regulation of cell deathGO:0060548810.013
membrane organizationGO:00610241120.013
regionalizationGO:00030024160.013
protein processingGO:0016485680.013
regulation of synaptic growth at neuromuscular junctionGO:0008582890.013
regulation of pole plasm oskar mrna localizationGO:0007317270.012
tube developmentGO:00352952440.012
regulation of cysteine type endopeptidase activityGO:2000116270.012
regulation of wnt signaling pathwayGO:0030111680.012
neuron projection guidanceGO:00974852410.012
dephosphorylationGO:0016311510.012
digestive system developmentGO:00551231490.012
monocarboxylic acid transportGO:001571830.012
nucleobase containing compound catabolic processGO:00346551650.012
positive regulation of cell developmentGO:0010720610.012
regulation of nucleoside metabolic processGO:0009118500.012
negative regulation of cellular protein metabolic processGO:0032269850.012
organelle fissionGO:00482853400.012
regulation of ras protein signal transductionGO:0046578930.012
regulation of multi organism processGO:00439001310.012
regulation of lipid transportGO:003236830.012
peripheral nervous system developmentGO:0007422520.012
mitotic cell cycle phase transitionGO:00447721380.012
regulation of cell cycle processGO:00105641810.012
oocyte anterior posterior axis specificationGO:0007314720.012
immune system developmentGO:0002520570.012
memoryGO:0007613940.012
single organism membrane organizationGO:0044802930.012
negative regulation of cell cycleGO:00457861160.012
dna metabolic processGO:00062592270.012
positive regulation of cellular protein metabolic processGO:00322701180.012
cell maturationGO:00484691440.012
negative regulation of phosphate metabolic processGO:0045936450.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
retina development in camera type eyeGO:006004140.011
cellular response to dna damage stimulusGO:00069742230.011
light induced release of internally sequestered calcium ionGO:000837710.011
protein complex assemblyGO:00064612000.011
gtp catabolic processGO:0006184720.011
extrinsic apoptotic signaling pathwayGO:009719110.011
guanosine containing compound catabolic processGO:1901069740.011
regulation of protein phosphorylationGO:0001932640.011
nucleobase containing compound transportGO:0015931560.011
axonogenesisGO:00074092900.011
vitamin metabolic processGO:000676620.011
stress activated protein kinase signaling cascadeGO:0031098550.011
salivary gland developmentGO:00074311620.011
regulation of erk1 and erk2 cascadeGO:0070372390.011
regulation of cell substrate adhesionGO:001081020.011
positive regulation of gtp catabolic processGO:0033126430.011
positive regulation of developmental processGO:00510941430.011
anterior posterior axis specification embryoGO:00085951030.011
gene silencingGO:00164581380.011
digestive tract morphogenesisGO:00485461270.011
retinal cell programmed cell deathGO:0046666250.011
oocyte developmentGO:00485991240.011
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
regulation of anatomical structure sizeGO:00900661630.011
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.011
negative regulation of intracellular signal transductionGO:1902532570.011
morphogenesis of an epitheliumGO:00020092760.011
positive regulation of neurotransmitter transportGO:005159020.011
chromatin modificationGO:00165681470.011
nucleoside triphosphate metabolic processGO:00091411200.011
response to nitrogen compoundGO:1901698900.011
divalent metal ion transportGO:0070838260.011
cellular response to molecule of bacterial originGO:007121930.011
cytoplasm organizationGO:0007028640.011
sensory perception of smellGO:0007608800.011
long chain fatty acid metabolic processGO:000167630.011
cytoplasmic transportGO:00164821300.011
regulation of stress activated mapk cascadeGO:0032872410.011
detection of chemical stimulus involved in sensory perceptionGO:0050907750.010
open tracheal system developmentGO:00074242040.010
molting cycle chitin based cuticleGO:0007591560.010
oocyte constructionGO:00073081120.010
sensory perception of mechanical stimulusGO:0050954720.010
covalent chromatin modificationGO:00165691060.010
glial cell differentiationGO:0010001350.010
response to uvGO:0009411240.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
response to inorganic substanceGO:0010035440.010
regulation of gtpase activityGO:0043087440.010
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.010
rhythmic behaviorGO:0007622760.010
chemical homeostasisGO:0048878920.010
protein kinase b signalingGO:004349110.010
synapse assemblyGO:00074161430.010
cellular response to nutrient levelsGO:0031669620.010
positive regulation of nervous system developmentGO:0051962690.010
segmentationGO:00352822070.010
ameboidal type cell migrationGO:00016671510.010
cellular homeostasisGO:0019725800.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.010
regulation of system processGO:0044057360.010
regulation of gene expression epigeneticGO:00400291280.010
regulation of anatomical structure morphogenesisGO:00226032420.010
camp metabolic processGO:0046058190.010

Calx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.076
nervous system diseaseDOID:86300.026
musculoskeletal system diseaseDOID:1700.021
cardiovascular system diseaseDOID:128700.016
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
cancerDOID:16200.013
eye diseaseDOID:561400.010
bone diseaseDOID:008000100.010
connective tissue diseaseDOID:6500.010