Drosophila melanogaster

20 known processes

l(2)dtl (Dmel_CG11295)

lethal-(2)-denticleless

(Aliases: DTL83,L2DTL,Dmel\CG11295,CG11295)

l(2)dtl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear divisionGO:00002803320.663
chromosome segregationGO:00070591570.654
meiotic chromosome segregationGO:0045132590.396
spindle organizationGO:00070512530.395
dna metabolic processGO:00062592270.294
Human
meiotic nuclear divisionGO:00071261510.238
single organism biosynthetic processGO:00447112060.218
Human
mitotic spindle organizationGO:00070522200.207
dna repairGO:0006281540.198
Human
cellular response to dna damage stimulusGO:00069742230.171
Human Zebrafish
organelle fissionGO:00482853400.166
male gamete generationGO:00482322010.158
regulation of cell cycleGO:00517262910.151
dendrite developmentGO:00163582040.133
mitotic spindle elongationGO:0000022810.130
protein complex biogenesisGO:00702712010.121
chromosome organizationGO:00512763600.120
positive regulation of response to stimulusGO:00485843230.117
tube morphogenesisGO:00352391910.113
spermatogenesisGO:00072832000.112
intracellular signal transductionGO:00355563000.109
imaginal disc derived appendage developmentGO:00487373990.105
cell recognitionGO:00080371020.104
male meiosisGO:0007140520.104
response to abiotic stimulusGO:00096283410.099
Human
dna conformation changeGO:00711031050.093
regulation of organelle organizationGO:00330431960.090
sister chromatid segregationGO:0000819920.083
mitotic nuclear divisionGO:00070672130.074
positive regulation of nucleobase containing compound metabolic processGO:00459353320.071
response to light stimulusGO:00094161240.071
Human
locomotory behaviorGO:00076261760.068
g2 dna damage checkpointGO:0031572690.068
Human Zebrafish
regulation of dna metabolic processGO:0051052340.068
protein complex assemblyGO:00064612000.068
microtubule organizing center organizationGO:00310231680.065
head involutionGO:0008258350.064
cell cycle phase transitionGO:00447701400.063
Zebrafish
nucleobase containing compound catabolic processGO:00346551650.062
imaginal disc derived appendage morphogenesisGO:00351143950.061
regulation of cell cycle processGO:00105641810.060
Zebrafish
cellular protein complex assemblyGO:0043623710.060
meiotic cell cycle processGO:19030461320.057
compound eye developmentGO:00487493070.057
post embryonic appendage morphogenesisGO:00351203850.057
imaginal disc derived wing morphogenesisGO:00074763370.057
phosphorylationGO:00163102940.056
homeostatic processGO:00425921990.056
cell fate determinationGO:0001709910.054
double strand break repairGO:0006302260.053
positive regulation of gene expressionGO:00106282900.052
centrosome cycleGO:00070981370.052
regulation of mitotic cell cycleGO:00073461900.052
Zebrafish
taxisGO:00423303040.051
spindle midzone assemblyGO:005125540.050
centrosome organizationGO:00512971630.050
spindle elongationGO:0051231830.049
appendage developmentGO:00487364010.048
mitotic cell cycle phase transitionGO:00447721380.047
Zebrafish
regionalizationGO:00030024160.047
positive regulation of macromolecule biosynthetic processGO:00105572830.046
organic substance catabolic processGO:19015753080.046
Human
response to organic substanceGO:00100332840.046
lipid biosynthetic processGO:0008610460.045
cellular ketone metabolic processGO:0042180240.045
positive regulation of cell communicationGO:00106472500.045
positive regulation of signal transductionGO:00099672230.045
meiosis iGO:0007127590.045
chromosome separationGO:0051304420.044
macromolecular complex assemblyGO:00650032560.044
axon developmentGO:00615642970.044
response to temperature stimulusGO:00092661060.042
regulation of microtubule cytoskeleton organizationGO:0070507410.041
meiotic cell cycleGO:00513211710.041
dendrite morphogenesisGO:00488131990.041
centrosome duplicationGO:00512981210.041
protein modification processGO:00362114380.041
Human
positive regulation of signalingGO:00230562430.040
protein dna complex subunit organizationGO:0071824860.040
positive regulation of macromolecule metabolic processGO:00106044050.039
agingGO:00075681430.038
regulation of phosphate metabolic processGO:00192202100.038
appendage morphogenesisGO:00351073970.037
morphogenesis of an epitheliumGO:00020092760.037
cell deathGO:00082192790.037
neuron recognitionGO:00080381010.037
regulation of tube sizeGO:0035150460.036
positive regulation of rna biosynthetic processGO:19026802660.036
regulation of dna recombinationGO:000001840.036
axonogenesisGO:00074092900.036
cellular response to radiationGO:0071478520.036
organelle assemblyGO:00709251980.035
programmed cell deathGO:00125012570.035
gastrulation with mouth forming firstGO:0001703360.035
dna packagingGO:0006323910.034
nucleosome organizationGO:0034728590.034
dna damage checkpointGO:0000077780.033
Human Zebrafish
dna biosynthetic processGO:0071897240.032
Human
small molecule metabolic processGO:00442813050.032
single organism cellular localizationGO:19025801800.032
protein catabolic processGO:00301631010.032
Human
organelle localizationGO:00516401480.031
protein localizationGO:00081042840.031
regulation of response to dna damage stimulusGO:2001020230.031
deathGO:00162652840.031
cuticle developmentGO:0042335860.031
protein phosphorylationGO:00064681690.031
response to monosaccharideGO:003428440.030
ribonucleotide metabolic processGO:00092591450.030
cellular catabolic processGO:00442483720.030
Human
dna integrity checkpointGO:0031570810.029
Human Zebrafish
positive regulation of molecular functionGO:00440931360.029
dna recombinationGO:0006310320.029
mitotic spindle midzone assemblyGO:005125610.029
mrna processingGO:00063971040.028
response to radiationGO:00093141550.028
Human
regulation of molecular functionGO:00650092170.027
positive regulation of cellular biosynthetic processGO:00313283160.027
regulation of intracellular signal transductionGO:19025312360.027
ion transportGO:00068111450.027
negative regulation of nucleobase containing compound metabolic processGO:00459342610.027
compound eye morphogenesisGO:00017452490.026
regulation of ras protein signal transductionGO:0046578930.026
single organism catabolic processGO:00447122280.026
cellular macromolecule localizationGO:00707272200.025
response to biotic stimulusGO:00096072940.025
cellular macromolecular complex assemblyGO:00346221530.025
epithelial tube morphogenesisGO:0060562880.025
organic cyclic compound catabolic processGO:19013611680.025
sensory organ morphogenesisGO:00905962600.025
immune responseGO:00069552460.024
wing disc morphogenesisGO:00074723440.024
male meiosis chromosome segregationGO:0007060100.024
establishment of cell polarityGO:0030010400.024
positive regulation of nitrogen compound metabolic processGO:00511733540.024
regulation of transportGO:00510491810.024
branching morphogenesis of an epithelial tubeGO:0048754450.024
inorganic cation transmembrane transportGO:0098662610.024
compound eye photoreceptor developmentGO:0042051780.024
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
heterocycle catabolic processGO:00467001660.023
regulation of cellular response to stressGO:0080135890.023
actin cytoskeleton organizationGO:00300362060.023
determination of adult lifespanGO:00083401370.023
regulation of chromatin silencingGO:0031935360.023
single organism behaviorGO:00447083910.023
immune system processGO:00023763470.022
regulation of mitotic cell cycle phase transitionGO:19019901300.022
Zebrafish
cellular component assembly involved in morphogenesisGO:00109271510.022
purine containing compound metabolic processGO:00725211550.022
carboxylic acid metabolic processGO:0019752920.022
wound healingGO:0042060750.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
negative regulation of cell cycle processGO:00109481090.021
Zebrafish
catabolic processGO:00090564090.021
Human
negative regulation of cell cycleGO:00457861160.021
Zebrafish
regulation of microtubule depolymerizationGO:0031114240.021
multicellular organismal agingGO:00102591400.021
mitotic sister chromatid segregationGO:0000070870.020
branching involved in open tracheal system developmentGO:0060446450.020
cell divisionGO:00513012480.020
dna replicationGO:0006260480.020
chemical homeostasisGO:0048878920.019
mitotic g2 m transition checkpointGO:0044818700.019
Zebrafish
digestive tract morphogenesisGO:00485461270.019
photoreceptor cell developmentGO:0042461960.019
purine nucleotide metabolic processGO:00061631460.019
establishment or maintenance of cell polarityGO:00071631670.019
sensory perceptionGO:00076001960.018
positive regulation of phosphate metabolic processGO:00459371390.018
eye developmentGO:00016543230.018
eye photoreceptor cell developmentGO:0042462810.018
response to organophosphorusGO:004668320.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
response to lipopolysaccharideGO:003249640.018
regulation of cell cycle phase transitionGO:19019871300.018
Zebrafish
regulation of hormone levelsGO:0010817400.017
apoptotic processGO:00069151590.017
phagocytosisGO:00069092150.017
enzyme linked receptor protein signaling pathwayGO:00071671790.017
lipid metabolic processGO:00066291210.017
tube developmentGO:00352952440.017
establishment of organelle localizationGO:00516561220.017
negative regulation of microtubule depolymerizationGO:0007026210.017
organic acid metabolic processGO:00060821030.017
eye photoreceptor cell differentiationGO:00017541450.016
segmentationGO:00352822070.016
positive regulation of cell cycle processGO:0090068280.016
mrna metabolic processGO:00160711240.016
regulation of cytokinesisGO:003246530.016
ras protein signal transductionGO:0007265880.016
intracellular mrna localizationGO:0008298660.016
atp metabolic processGO:0046034490.016
axon guidanceGO:00074112330.015
mitotic chromosome condensationGO:0007076220.015
cellular response to nutrient levelsGO:0031669620.015
positive regulation of rna metabolic processGO:00512542710.015
establishment of localization in cellGO:00516494020.015
regulation of anatomical structure sizeGO:00900661630.015
hindgut morphogenesisGO:0007442580.015
protein dna complex assemblyGO:0065004630.015
positive regulation of biosynthetic processGO:00098913160.015
negative regulation of mitotic cell cycleGO:00459301090.015
Zebrafish
small gtpase mediated signal transductionGO:0007264880.015
regulation of double strand break repairGO:200077930.015
vesicle mediated transportGO:00161923810.014
Worm
positive regulation of intracellular signal transductionGO:19025331160.014
chromatin organizationGO:00063252070.014
cilium morphogenesisGO:0060271390.014
purine containing compound catabolic processGO:00725231120.014
cellular protein localizationGO:00346131600.014
gland morphogenesisGO:00226121450.014
maintenance of locationGO:0051235730.014
connective tissue developmentGO:006144830.014
tissue migrationGO:00901301550.014
asymmetric protein localization involved in cell fate determinationGO:004516790.014
establishment of planar polarityGO:0001736870.014
regulation of protein depolymerizationGO:1901879270.014
transmembrane transportGO:00550851390.014
dna endoreduplicationGO:0042023220.014
mitotic cytokinesisGO:0000281500.014
nucleoside phosphate metabolic processGO:00067531620.014
positive regulation of cell cycleGO:0045787430.014
salivary gland morphogenesisGO:00074351450.014
regulation of cell deathGO:00109411730.013
regulation of chromosome organizationGO:0033044640.013
regulation of cell shapeGO:00083601130.013
organonitrogen compound catabolic processGO:19015651280.013
digestive tract developmentGO:00485651490.013
carbohydrate derivative metabolic processGO:19011352170.013
anatomical structure homeostasisGO:0060249970.013
cell cycle checkpointGO:0000075950.013
Human Zebrafish
regulation of multicellular organismal developmentGO:20000264140.013
Worm
response to other organismGO:00517072930.013
salivary gland developmentGO:00074311620.013
embryonic morphogenesisGO:00485982060.013
renal tubule developmentGO:0061326640.013
negative regulation of organelle organizationGO:0010639560.013
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.013
developmental growthGO:00485892800.013
Worm
aromatic compound catabolic processGO:00194391660.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
regulation of dna repairGO:000628250.013
gastrulationGO:0007369700.013
regulation of phosphorus metabolic processGO:00511742100.012
axis specificationGO:00097981670.012
cellular response to abiotic stimulusGO:0071214580.012
mitotic dna integrity checkpointGO:0044774750.012
Zebrafish
negative regulation of cell communicationGO:00106482230.012
regulation of tube size open tracheal systemGO:0035151430.012
nucleobase containing small molecule metabolic processGO:00550861740.012
cellular nitrogen compound catabolic processGO:00442701650.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
cell type specific apoptotic processGO:0097285380.012
hormone biosynthetic processGO:0042446200.012
cellular response to organic substanceGO:00713101320.012
ribose phosphate metabolic processGO:00196931450.012
organic substance transportGO:00717022570.012
compound eye photoreceptor cell differentiationGO:00017511400.012
blastoderm segmentationGO:00073501590.012
purine ribonucleotide catabolic processGO:00091541090.012
nucleoside triphosphate catabolic processGO:00091431080.012
regulation of programmed cell deathGO:00430671520.012
protein targetingGO:0006605640.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
cellular amine metabolic processGO:0044106120.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
mitotic g2 dna damage checkpointGO:0007095690.011
Zebrafish
photoreceptor cell differentiationGO:00465301700.011
cellular lipid metabolic processGO:0044255830.011
regulation of sister chromatid cohesionGO:000706320.011
rna 3 end processingGO:0031123450.011
positive regulation of phosphorus metabolic processGO:00105621390.011
regulation of neuron projection developmentGO:0010975690.011
cellular protein catabolic processGO:0044257830.011
Human
establishment of protein localizationGO:00451841630.011
ecdysteroid biosynthetic processGO:0045456150.011
cell adhesionGO:00071551360.011
cellular protein modification processGO:00064644380.011
Human
transcription from rna polymerase ii promoterGO:00063663680.011
mitotic dna damage checkpointGO:0044773740.011
Zebrafish
ribonucleoside catabolic processGO:00424541120.011
proteasomal protein catabolic processGO:0010498590.011
body morphogenesisGO:001017120.011
regulation of transferase activityGO:0051338580.011
amine metabolic processGO:0009308120.011
antimicrobial humoral responseGO:0019730990.011
nucleoside phosphate catabolic processGO:19012921100.011
asymmetric protein localizationGO:0008105330.010
gene silencingGO:00164581380.010
proteolysisGO:00065081920.010
Human
protein complex disassemblyGO:0043241360.010
regulation of cellular component sizeGO:0032535980.010
regulation of response to biotic stimulusGO:0002831630.010
response to bacteriumGO:00096171980.010
response to external biotic stimulusGO:00432072930.010
aggressive behaviorGO:0002118630.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
cation transportGO:00068121100.010
regulation of dna dependent dna replicationGO:009032960.010

l(2)dtl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
organ system cancerDOID:005068600.025
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025