Drosophila melanogaster

7 known processes

modSP (Dmel_CG31217)

modular serine protease

(Aliases: ModSP,CT28389,CG10100,W,SP172,Ldlr,LDL,CG17557,Dmel\CG31217,Ser89E,X,SP53,Dm-SP,CG31217)

modSP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of innate immune responseGO:000221840.814
immune response activating signal transductionGO:000275720.673
pattern recognition receptor signaling pathwayGO:000222120.655
innate immune response activating signal transductionGO:000275820.628
peptidoglycan catabolic processGO:000925330.622
immune responseGO:00069552460.622
glycosaminoglycan catabolic processGO:000602730.604
peptidoglycan metabolic processGO:000027030.558
detection of stimulusGO:00516061560.513
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.486
positive regulation of response to stimulusGO:00485843230.444
immune response regulating signaling pathwayGO:000276420.431
defense response to other organismGO:00985422250.426
immune system processGO:00023763470.391
aminoglycan catabolic processGO:000602660.384
innate immune responseGO:00450871440.379
response to fungusGO:0009620500.358
immune effector processGO:0002252980.345
regulation of immune responseGO:00507761180.317
regulation of response to stressGO:00801342000.314
regulation of innate immune responseGO:0045088710.313
regulation of defense responseGO:00313471020.305
defense response to bacteriumGO:00427421780.295
antimicrobial humoral responseGO:0019730990.288
defense response to gram positive bacteriumGO:0050830410.288
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.222
glycosaminoglycan metabolic processGO:0030203110.220
response to biotic stimulusGO:00096072940.213
antibacterial humoral responseGO:0019731440.210
positive regulation of immune responseGO:0050778630.208
regulation of antimicrobial humoral responseGO:0002759500.188
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.179
humoral immune responseGO:00069591170.178
organelle fissionGO:00482853400.175
response to bacteriumGO:00096171980.171
positive regulation of melanization defense responseGO:003500810.158
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.156
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.152
regulation of immune effector processGO:0002697520.145
antifungal humoral responseGO:0019732120.140
regulation of humoral immune responseGO:0002920510.140
organonitrogen compound metabolic processGO:19015643180.135
response to external biotic stimulusGO:00432072930.132
regulation of immune system processGO:00026821760.131
regionalizationGO:00030024160.130
melanization defense responseGO:0035006450.130
positive regulation of defense responseGO:0031349590.129
response to other organismGO:00517072930.127
antibacterial peptide biosynthetic processGO:0002780220.123
phenol containing compound metabolic processGO:0018958570.123
defense responseGO:00069523000.121
negative regulation of defense response to bacteriumGO:190042570.119
defense response to fungusGO:0050832480.116
antimicrobial peptide productionGO:0002775460.110
axis specificationGO:00097981670.109
production of molecular mediator of immune responseGO:0002440460.106
regulation of defense response to bacteriumGO:1900424300.106
detection of chemical stimulusGO:0009593930.106
aminoglycan metabolic processGO:0006022180.105
nuclear divisionGO:00002803320.094
positive regulation of response to external stimulusGO:0032103440.089
antibacterial peptide productionGO:0002778220.087
regulation of antimicrobial peptide biosynthetic processGO:0002805380.086
positive regulation of cellular biosynthetic processGO:00313283160.086
positive regulation of immune system processGO:0002684680.084
regulation of multi organism processGO:00439001310.082
carbohydrate derivative metabolic processGO:19011352170.081
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.074
organic substance catabolic processGO:19015753080.072
detection of external biotic stimulusGO:009858120.072
positive regulation of response to biotic stimulusGO:0002833310.069
cellular amide metabolic processGO:0043603800.067
defense response to gram negative bacteriumGO:0050829940.065
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.062
amide biosynthetic processGO:0043604420.062
response to organic substanceGO:00100332840.061
positive regulation of biosynthetic processGO:00098913160.059
organic substance transportGO:00717022570.059
lipopolysaccharide mediated signaling pathwayGO:003166310.058
organonitrogen compound catabolic processGO:19015651280.057
carbohydrate derivative catabolic processGO:19011361180.057
positive regulation of antimicrobial peptide productionGO:0002225280.057
melanin metabolic processGO:0006582470.056
meiotic cell cycleGO:00513211710.053
endocytosisGO:00068973100.053
regulation of cellular amide metabolic processGO:0034248390.053
antimicrobial peptide biosynthetic processGO:0002777380.052
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.052
positive regulation of innate immune responseGO:0045089380.052
tissue morphogenesisGO:00487292970.052
regulation of response to external stimulusGO:00321011150.051
regulation of antibacterial peptide biosynthetic processGO:0002808220.050
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.050
macromolecule catabolic processGO:00090571610.048
regulation of production of molecular mediator of immune responseGO:0002700440.048
epithelial cell differentiationGO:00308553220.048
positive regulation of nitrogen compound metabolic processGO:00511733540.047
positive regulation of signal transductionGO:00099672230.047
vesicle mediated transportGO:00161923810.047
negative regulation of cellular metabolic processGO:00313243820.047
organonitrogen compound biosynthetic processGO:19015661170.046
meiotic nuclear divisionGO:00071261510.044
cell adhesionGO:00071551360.044
positive regulation of signalingGO:00230562430.044
establishment of protein localizationGO:00451841630.043
negative regulation of signalingGO:00230572190.043
regulation of melanization defense responseGO:003500760.043
catabolic processGO:00090564090.042
defense response to virusGO:0051607230.042
negative regulation of immune responseGO:0050777390.040
dorsal ventral axis specificationGO:0009950660.040
regulation of antibacterial peptide productionGO:0002786220.040
negative regulation of response to stimulusGO:00485852580.040
regulation of antimicrobial peptide productionGO:0002784440.039
negative regulation of gene expressionGO:00106293870.039
regulation of intracellular signal transductionGO:19025312360.039
negative regulation of immune system processGO:0002683500.038
secondary metabolic processGO:0019748750.037
intracellular signal transductionGO:00355563000.037
phagocytosisGO:00069092150.037
mitotic spindle organizationGO:00070522200.037
negative regulation of cell communicationGO:00106482230.035
response to woundingGO:0009611940.035
positive regulation of immune effector processGO:0002699280.034
spindle organizationGO:00070512530.033
organic hydroxy compound metabolic processGO:1901615830.033
cellular response to organic substanceGO:00713101320.033
nucleocytoplasmic transportGO:0006913720.033
epithelial cell developmentGO:00020642740.033
peptide metabolic processGO:0006518800.032
appendage developmentGO:00487364010.032
pigment metabolic processGO:0042440840.032
positive regulation of humoral immune responseGO:0002922280.031
imaginal disc derived wing morphogenesisGO:00074763370.030
regulation of phosphorus metabolic processGO:00511742100.030
protein transportGO:00150311550.030
matingGO:00076181200.030
protein maturationGO:0051604710.030
locomotory behaviorGO:00076261760.030
endomembrane system organizationGO:00102561190.029
carboxylic acid metabolic processGO:0019752920.028
protein localizationGO:00081042840.028
activation of immune responseGO:000225350.028
protein processingGO:0016485680.028
negative regulation of signal transductionGO:00099682060.028
tube developmentGO:00352952440.028
response to peptidoglycanGO:003249420.028
positive regulation of defense response to bacteriumGO:1900426230.027
positive regulation of cellular amide metabolic processGO:0034250260.027
protein complex biogenesisGO:00702712010.027
positive regulation of production of molecular mediator of immune responseGO:0002702280.026
regulation of response to biotic stimulusGO:0002831630.026
single organism intracellular transportGO:19025822070.026
negative regulation of defense responseGO:0031348350.026
cellular protein localizationGO:00346131600.026
positive regulation of antibacterial peptide productionGO:0002803200.025
regulation of cellular localizationGO:00603411360.025
peptide biosynthetic processGO:0043043420.024
determination of adult lifespanGO:00083401370.024
phosphorylationGO:00163102940.024
regulation of transcription from rna polymerase ii promoterGO:00063573780.024
detection of molecule of fungal originGO:003249110.024
proteolysisGO:00065081920.023
positive regulation of transcription factor import into nucleusGO:0042993190.023
intracellular transportGO:00469072280.023
positive regulation of intracellular signal transductionGO:19025331160.023
regulation of mrna metabolic processGO:1903311720.022
regulation of cell shapeGO:00083601130.022
cellular response to lipopolysaccharideGO:007122230.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
response to lipopolysaccharideGO:003249640.022
cellular response to chemical stimulusGO:00708871990.021
regulation of mapk cascadeGO:0043408920.021
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.021
single organism cellular localizationGO:19025801800.021
positive regulation of cell communicationGO:00106472500.020
toll signaling pathwayGO:0008063250.020
regulation of cell morphogenesisGO:00226041630.020
wound healingGO:0042060750.020
melanotic encapsulation of foreign targetGO:0035011300.020
rna processingGO:00063961470.019
meiotic cell cycle processGO:19030461320.019
negative regulation of innate immune responseGO:0045824300.019
mrna metabolic processGO:00160711240.019
embryonic pattern specificationGO:00098801740.019
mapk cascadeGO:00001651070.019
regulation of anatomical structure morphogenesisGO:00226032420.019
positive regulation of cell migrationGO:003033520.019
appendage morphogenesisGO:00351073970.019
body morphogenesisGO:001017120.019
actin filament based processGO:00300292200.019
regulation of localizationGO:00328792750.019
positive regulation of cellular component organizationGO:00511301560.019
establishment of localization in cellGO:00516494020.019
tube morphogenesisGO:00352391910.018
regulation of multicellular organismal developmentGO:20000264140.018
dorsal ventral pattern formationGO:00099531330.018
spermatogenesisGO:00072832000.018
imaginal disc derived appendage developmentGO:00487373990.018
response to oxygen containing compoundGO:19017002000.018
eye morphogenesisGO:00485922600.018
stem cell differentiationGO:00488631170.018
jnk cascadeGO:0007254500.018
cellular catabolic processGO:00442483720.018
muscle organ developmentGO:00075171270.017
rna localizationGO:00064031150.017
actin cytoskeleton organizationGO:00300362060.017
positive regulation of antimicrobial humoral responseGO:0002760280.017
stress activated protein kinase signaling cascadeGO:0031098550.017
positive regulation of multi organism processGO:0043902400.017
signal transduction by phosphorylationGO:00230141070.017
response to organophosphorusGO:004668320.017
nucleotide metabolic processGO:00091171610.016
response to molecule of fungal originGO:000223810.016
segmentationGO:00352822070.016
multicellular organismal agingGO:00102591400.016
nuclear transportGO:0051169720.016
cellular protein modification processGO:00064644380.016
wing disc morphogenesisGO:00074723440.016
protein modification processGO:00362114380.016
mesenchymal cell differentiationGO:004876210.016
regulation of transportGO:00510491810.016
morphogenesis of an epitheliumGO:00020092760.015
post embryonic appendage morphogenesisGO:00351203850.015
membrane organizationGO:00610241120.015
organelle assemblyGO:00709251980.015
organic acid metabolic processGO:00060821030.015
small molecule metabolic processGO:00442813050.015
positive regulation of protein transportGO:0051222370.015
male meiosisGO:0007140520.015
response to nitrogen compoundGO:1901698900.015
negative regulation of nitrogen compound metabolic processGO:00511722650.015
regulation of protein transportGO:0051223570.015
nitrogen compound transportGO:0071705850.015
mitotic nuclear divisionGO:00070672130.015
oxoacid metabolic processGO:00434361030.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
regulation of secondary metabolic processGO:004345570.015
epithelial tube morphogenesisGO:0060562880.015
ion transportGO:00068111450.014
aggressive behaviorGO:0002118630.014
stress activated mapk cascadeGO:0051403520.014
peptidoglycan recognition protein signaling pathwayGO:0061057160.014
cytoplasmic transportGO:00164821300.014
regulation of stress activated mapk cascadeGO:0032872410.014
cellular macromolecule localizationGO:00707272200.014
negative regulation of biosynthetic processGO:00098902770.014
negative regulation of response to external stimulusGO:0032102220.014
mrna splicing via spliceosomeGO:0000398730.014
stem cell proliferationGO:0072089880.014
anterior posterior axis specification embryoGO:00085951030.014
dendrite developmentGO:00163582040.014
positive regulation of intracellular protein transportGO:0090316300.014
mesenchymal cell developmentGO:001403110.014
macromolecular complex assemblyGO:00650032560.014
sleepGO:0030431490.014
developmental maturationGO:00217001720.013
regulation of cellular response to stressGO:0080135890.013
cell migrationGO:00164772380.013
maintenance of locationGO:0051235730.013
negative regulation of developmental processGO:00510932010.013
lateral inhibitionGO:00463312060.013
non sensory hair organizationGO:0035316470.013
compound eye developmentGO:00487493070.013
regulation of phosphate metabolic processGO:00192202100.013
response to glucoseGO:000974920.013
biological adhesionGO:00226101380.013
regulation of stress activated protein kinase signaling cascadeGO:0070302420.013
homeostatic processGO:00425921990.013
mrna processingGO:00063971040.013
organophosphate metabolic processGO:00196371950.013
growthGO:00400073590.013
chromosome organizationGO:00512763600.013
eye developmentGO:00016543230.013
very long chain fatty acid metabolic processGO:000003840.012
cellular response to biotic stimulusGO:007121640.012
regulation of cell differentiationGO:00455953020.012
negative regulation of mapk cascadeGO:0043409230.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
female meiotic divisionGO:0007143700.012
organelle localizationGO:00516401480.012
transcription from rna polymerase ii promoterGO:00063663680.012
regulation of organ morphogenesisGO:2000027780.012
positive regulation of transportGO:0051050920.012
wnt signaling pathwayGO:0016055980.012
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.012
chemotaxisGO:00069352490.012
regulation of intracellular protein transportGO:0033157460.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
rna splicingGO:0008380830.012
gene silencing by rnaGO:0031047570.012
heterocycle catabolic processGO:00467001660.012
spindle assemblyGO:0051225800.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
negative regulation of multicellular organismal processGO:00512411420.012
g protein coupled receptor signaling pathwayGO:00071861360.012
ras protein signal transductionGO:0007265880.012
regulation of cell cycle processGO:00105641810.012
regulation of proteolysisGO:0030162870.012
regulation of jnk cascadeGO:0046328400.011
regulation of peptidase activityGO:0052547390.011
cell cycle phase transitionGO:00447701400.011
mitotic cell cycle phase transitionGO:00447721380.011
purine containing compound metabolic processGO:00725211550.011
positive regulation of molecular functionGO:00440931360.011
morphogenesis of a branching structureGO:0001763450.011
regulation of toll signaling pathwayGO:0008592170.011
cellular response to dna damage stimulusGO:00069742230.011
regulation of cellular component biogenesisGO:00440872010.011
cellular response to lipidGO:0071396200.011
response to organic cyclic compoundGO:0014070890.011
negative regulation of cellular protein metabolic processGO:0032269850.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
cellular macromolecular complex assemblyGO:00346221530.011
response to endogenous stimulusGO:00097191190.011
regulation of nervous system developmentGO:00519602480.011
cellular amino acid metabolic processGO:0006520610.011
skeletal muscle fiber developmentGO:004874130.011
nucleoside triphosphate catabolic processGO:00091431080.011
negative regulation of rna biosynthetic processGO:19026792400.011
synaptic transmissionGO:00072682880.011
positive regulation of cell motilityGO:200014730.011
neurological system processGO:00508773580.011
ovarian follicle cell developmentGO:00307072480.011
regulation of molecular functionGO:00650092170.011
regulation of cell developmentGO:00602842150.011
response to mechanical stimulusGO:0009612280.010
camera type eye developmentGO:004301040.010
extrinsic apoptotic signaling pathwayGO:009719110.010
regulation of cytoplasmic transportGO:1903649470.010
imaginal disc pattern formationGO:0007447910.010
glycosyl compound metabolic processGO:19016571270.010
cellular protein complex assemblyGO:0043623710.010
regulation of nucleocytoplasmic transportGO:0046822350.010
regulation of cell substrate adhesionGO:001081020.010
intracellular protein transportGO:00068861040.010
retina development in camera type eyeGO:006004140.010
cell maturationGO:00484691440.010

modSP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013