IMP: Integrative Multi-species Prediction

Drosophila melanogaster

88 known processes

sns (Dmel_CG33141)

sticks and stones

(Aliases: 43-49,CG13754,CG18464,Dmel\CG33141,CG13753,CG13752,CG2385,sns20,CG33141,CT33230,CG8278,CG13755,SNS,CG12495,Sens,CT33232,rost,Sns)

Entrez: 44097
FLYBASE: FBgn0024189
UniProtKB: A1Z7J1
UniProtKB: Q0E9F2

Process Predictions
Disease Predictions

sns biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
striated muscle cell differentiation	GO:0051146	90	1.000
syncytium formation by plasma membrane fusion	GO:0000768	43	1.000
myoblast fusion	GO:0007520	43	1.000
muscle structure development	GO:0061061	224	1.000
regulation of muscle organ development	GO:0048634	13	1.000	Fly
muscle cell differentiation	GO:0042692	103	0.999
eye development	GO:0001654	323	0.998
regulation of myoblast fusion	GO:1901739	6	0.997	Fly
regulation of striated muscle tissue development	GO:0016202	5	0.996	Fly
syncytium formation	GO:0006949	43	0.992
muscle tissue development	GO:0060537	30	0.992	Zebrafish Mouse Fly
regulation of syncytium formation by plasma membrane fusion	GO:0060142	6	0.990	Fly
striated muscle tissue development	GO:0014706	27	0.983	Zebrafish Mouse Fly
regulation of cell differentiation	GO:0045595	302	0.978	Fly
muscle organ development	GO:0007517	127	0.966
spermatogenesis	GO:0007283	200	0.963
regulation of anatomical structure morphogenesis	GO:0022603	242	0.961	Fly
myotube differentiation	GO:0014902	46	0.950
sensory organ morphogenesis	GO:0090596	260	0.931
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.930
tube development	GO:0035295	244	0.923	Fly
nephrocyte filtration	GO:0097206	7	0.914
dendrite morphogenesis	GO:0048813	199	0.911
negative regulation of rna biosynthetic process	GO:1902679	240	0.907
tissue morphogenesis	GO:0048729	297	0.895	Fly
muscle cell development	GO:0055001	50	0.894	Zebrafish
epithelial cell differentiation	GO:0030855	322	0.892	Fly
visceral muscle development	GO:0007522	14	0.892
male gamete generation	GO:0048232	201	0.887
central nervous system development	GO:0007417	201	0.877	Fly
compound eye photoreceptor cell differentiation	GO:0001751	140	0.872	Fly
renal filtration	GO:0097205	7	0.848
spermatid differentiation	GO:0048515	114	0.847
regulation of myotube differentiation	GO:0010830	6	0.829	Fly
kidney development	GO:0001822	3	0.791	Zebrafish
dendrite development	GO:0016358	204	0.787
regulation of muscle tissue development	GO:1901861	5	0.783	Fly
morphogenesis of an epithelium	GO:0002009	276	0.771	Fly
compound eye morphogenesis	GO:0001745	249	0.758
organ formation	GO:0048645	39	0.743
negative regulation of transcription dna templated	GO:0045892	237	0.743
skeletal muscle organ development	GO:0060538	48	0.731	Zebrafish Mouse
epithelial cell development	GO:0002064	274	0.730	Fly
tube morphogenesis	GO:0035239	191	0.725	Fly
compound eye development	GO:0048749	307	0.708
growth	GO:0040007	359	0.707	Fly
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.665
eye morphogenesis	GO:0048592	260	0.660
striated muscle cell development	GO:0055002	50	0.656	Zebrafish
negative regulation of biosynthetic process	GO:0009890	277	0.636
cell fate specification	GO:0001708	71	0.621	Fly
gland development	GO:0048732	191	0.613
positive regulation of transcription dna templated	GO:0045893	266	0.593
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.591
positive regulation of macromolecule metabolic process	GO:0010604	405	0.590	Fly
regionalization	GO:0003002	416	0.589	Fly
cuticle pattern formation	GO:0035017	27	0.588	Fly
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.571
salivary gland development	GO:0007431	162	0.568
skeletal muscle tissue development	GO:0007519	13	0.565	Zebrafish Mouse
negative regulation of cellular metabolic process	GO:0031324	382	0.564
epidermis development	GO:0008544	65	0.537
cell proliferation	GO:0008283	299	0.532
negative regulation of signal transduction	GO:0009968	206	0.529	Fly
establishment of ommatidial planar polarity	GO:0042067	49	0.511	Fly
cuticle development	GO:0042335	86	0.500	Fly
regulation of multicellular organismal development	GO:2000026	414	0.498	Fly
negative regulation of cell proliferation	GO:0008285	69	0.493
imaginal disc derived appendage development	GO:0048737	399	0.491	Fly
cell motility	GO:0048870	251	0.491
cell death	GO:0008219	279	0.481
cell cycle phase transition	GO:0044770	140	0.473
salivary gland morphogenesis	GO:0007435	145	0.459
negative regulation of neurogenesis	GO:0050768	53	0.447	Fly
epithelial tube morphogenesis	GO:0060562	88	0.443	Fly
cardiac muscle tissue development	GO:0048738	9	0.442
regulation of cell fate commitment	GO:0010453	29	0.440	Fly
cell cell adhesion	GO:0098609	26	0.438
renal tubule development	GO:0061326	64	0.437	Fly
camera type eye development	GO:0043010	4	0.437
eye photoreceptor cell differentiation	GO:0001754	145	0.436	Fly
transcription from rna polymerase ii promoter	GO:0006366	368	0.436
exocrine system development	GO:0035272	162	0.432
adult chitin based cuticle development	GO:0008365	2	0.426	Fly
negative regulation of multicellular organismal process	GO:0051241	142	0.401	Fly
cardiovascular system development	GO:0072358	82	0.396
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.393
regulation of muscle cell differentiation	GO:0051147	8	0.392	Fly
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.388
imaginal disc derived wing morphogenesis	GO:0007476	337	0.388	Fly
circulatory system development	GO:0072359	82	0.381
negative regulation of cell differentiation	GO:0045596	143	0.379	Fly
positive regulation of rna metabolic process	GO:0051254	271	0.372
lateral inhibition	GO:0046331	206	0.371	Fly
regulation of cell proliferation	GO:0042127	163	0.363
cardiocyte differentiation	GO:0035051	29	0.360
negative regulation of rna metabolic process	GO:0051253	251	0.353
digestive system development	GO:0055123	149	0.350
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.348
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.347	Fly
renal system development	GO:0072001	72	0.345
localization of cell	GO:0051674	257	0.344
hematopoietic or lymphoid organ development	GO:0048534	57	0.342
cardioblast differentiation	GO:0010002	20	0.336
somatic muscle development	GO:0007525	66	0.333
larval visceral muscle development	GO:0007523	9	0.328
regulation of notch signaling pathway	GO:0008593	100	0.323	Fly
muscle organ morphogenesis	GO:0048644	7	0.320	Fly
positive regulation of gene expression	GO:0010628	290	0.312
malpighian tubule development	GO:0072002	64	0.306	Fly
regulation of developmental growth	GO:0048638	174	0.304	Fly
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.303
negative regulation of developmental process	GO:0051093	201	0.302	Fly
notch signaling pathway	GO:0007219	120	0.299	Fly
regulation of growth	GO:0040008	233	0.296	Fly
multi organism behavior	GO:0051705	175	0.292	Fly
head development	GO:0060322	135	0.289	Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.289	Fly
actin cytoskeleton organization	GO:0030036	206	0.287
gland morphogenesis	GO:0022612	145	0.285
extracellular structure organization	GO:0043062	46	0.283
negative regulation of nervous system development	GO:0051961	92	0.283	Fly
positive regulation of response to stimulus	GO:0048584	323	0.281	Fly
regulation of protein complex assembly	GO:0043254	42	0.281	Mouse
regulation of cell morphogenesis	GO:0022604	163	0.279	Fly
cell migration	GO:0016477	238	0.276
developmental growth	GO:0048589	280	0.275	Fly
negative regulation of signaling	GO:0023057	219	0.271	Fly
regulation of smoothened signaling pathway	GO:0008589	28	0.258
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules	GO:0007157	8	0.250
anterior posterior pattern specification	GO:0009952	136	0.250
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.248	Fly
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.239
malpighian tubule morphogenesis	GO:0007443	44	0.237
positive regulation of endopeptidase activity	GO:0010950	26	0.237	Fly
regulation of cell death	GO:0010941	173	0.232
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.229
apoptotic process	GO:0006915	159	0.228
embryonic morphogenesis	GO:0048598	206	0.226	Fly
epithelial cell migration open tracheal system	GO:0007427	32	0.225
axon guidance	GO:0007411	233	0.224
negative regulation of response to stimulus	GO:0048585	258	0.221	Fly
positive regulation of biosynthetic process	GO:0009891	316	0.218
regulation of actin filament length	GO:0030832	27	0.217	Mouse
ovarian follicle cell development	GO:0030707	248	0.215	Fly
cellularization	GO:0007349	90	0.214
cellular macromolecular complex assembly	GO:0034622	153	0.207	Mouse
appendage development	GO:0048736	401	0.207	Fly
circadian rhythm	GO:0007623	105	0.207
response to endogenous stimulus	GO:0009719	119	0.206
cell fate determination	GO:0001709	91	0.203
actin filament based process	GO:0030029	220	0.200
positive regulation of protein metabolic process	GO:0051247	128	0.196	Fly
regulation of cell fate specification	GO:0042659	27	0.195	Fly
regulation of programmed cell death	GO:0043067	152	0.193
photoreceptor cell differentiation	GO:0046530	170	0.191	Fly
nephron development	GO:0072006	3	0.187	Zebrafish
kidney epithelium development	GO:0072073	3	0.184
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.181	Fly
larval development	GO:0002164	104	0.179
regulation of apoptotic process	GO:0042981	130	0.178
morphogenesis of a branching epithelium	GO:0061138	45	0.177	Fly
aggressive behavior	GO:0002118	63	0.177	Fly
eye photoreceptor cell fate commitment	GO:0042706	37	0.174
urogenital system development	GO:0001655	72	0.172
establishment or maintenance of cell polarity	GO:0007163	167	0.168	Fly
notch receptor processing	GO:0007220	13	0.165	Fly
regulation of organ morphogenesis	GO:2000027	78	0.164
respiratory system development	GO:0060541	213	0.164	Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.163
columnar cuboidal epithelial cell development	GO:0002066	249	0.162	Fly
cell division	GO:0051301	248	0.161
brain development	GO:0007420	120	0.159	Fly
pharynx development	GO:0060465	1	0.157
cellular component assembly involved in morphogenesis	GO:0010927	151	0.156	Fly
immune system process	GO:0002376	347	0.155
muscle attachment	GO:0016203	36	0.154
positive regulation of rna biosynthetic process	GO:1902680	266	0.151
skin development	GO:0043588	65	0.151
filtration diaphragm assembly	GO:0036058	4	0.145
embryonic organ development	GO:0048568	50	0.142
heart development	GO:0007507	82	0.142
positive regulation of cellular biosynthetic process	GO:0031328	316	0.142
spermatid development	GO:0007286	98	0.142
regulation of neurogenesis	GO:0050767	158	0.138	Fly
nephrocyte differentiation	GO:0061319	12	0.138
neuron projection guidance	GO:0097485	241	0.132
negative regulation of cellular biosynthetic process	GO:0031327	277	0.131
segmentation	GO:0035282	207	0.128
actin polymerization or depolymerization	GO:0008154	31	0.127	Mouse
actin filament organization	GO:0007015	126	0.126	Mouse Fly
branching morphogenesis of an epithelial tube	GO:0048754	45	0.125	Fly
regulation of cellular component biogenesis	GO:0044087	201	0.123	Mouse
regulation of actin filament polymerization	GO:0030833	25	0.123	Mouse
cell adhesion	GO:0007155	136	0.121
wing disc morphogenesis	GO:0007472	344	0.121	Fly
mesodermal cell differentiation	GO:0048333	7	0.120
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.120
negative regulation of cell communication	GO:0010648	223	0.119	Fly
chaeta morphogenesis	GO:0008407	42	0.118
negative regulation of gene expression	GO:0010629	387	0.117
heart morphogenesis	GO:0003007	32	0.116
eye antennal disc development	GO:0035214	60	0.113
nephron epithelium development	GO:0072009	3	0.113
stem cell differentiation	GO:0048863	117	0.111
formation of organ boundary	GO:0010160	30	0.111
appendage morphogenesis	GO:0035107	397	0.111	Fly
positive regulation of signaling	GO:0023056	243	0.109	Fly
cell cell junction assembly	GO:0007043	38	0.108
death	GO:0016265	284	0.107
open tracheal system development	GO:0007424	204	0.106	Fly
positive regulation of muscle organ development	GO:0048636	6	0.105
protein complex biogenesis	GO:0070271	201	0.103	Mouse
eye antennal disc morphogenesis	GO:0007455	34	0.103
synapse organization	GO:0050808	196	0.103	Worm
cilium assembly	GO:0042384	38	0.099
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.098	Fly
single organism cell adhesion	GO:0098602	47	0.098	Fly
gliogenesis	GO:0042063	80	0.096
regulation of striated muscle cell differentiation	GO:0051153	8	0.095	Fly
inter male aggressive behavior	GO:0002121	60	0.095	Fly
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.093
regulation of cell shape	GO:0008360	113	0.092	Fly
regulation of organelle organization	GO:0033043	196	0.090	Mouse Fly
axonogenesis	GO:0007409	290	0.090
mesodermal cell fate specification	GO:0007501	2	0.089
antennal development	GO:0007469	25	0.088
regulation of cell development	GO:0060284	215	0.088	Fly
adherens junction organization	GO:0034332	27	0.087
rna processing	GO:0006396	147	0.085
smoothened signaling pathway	GO:0007224	49	0.084
protein modification process	GO:0036211	438	0.084
positive regulation of protein complex assembly	GO:0031334	22	0.083	Mouse
embryonic pattern specification	GO:0009880	174	0.083
formation of anatomical boundary	GO:0048859	37	0.082
chitin based cuticle development	GO:0040003	49	0.082	Fly
phosphorylation	GO:0016310	294	0.081	Mouse
myotube cell development	GO:0014904	3	0.080	Zebrafish
locomotor rhythm	GO:0045475	56	0.080
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.079
positive regulation of peptidase activity	GO:0010952	29	0.078	Fly
sarcomere organization	GO:0045214	26	0.078
negative regulation of programmed cell death	GO:0043069	72	0.077
positive regulation of cell differentiation	GO:0045597	64	0.077
branching involved in open tracheal system development	GO:0060446	45	0.077	Fly
muscle tissue morphogenesis	GO:0060415	2	0.075
regulation of molecular function	GO:0065009	217	0.075	Fly
programmed cell death	GO:0012501	257	0.074
malpighian tubule stellate cell differentiation	GO:0061330	3	0.074	Fly
compound eye photoreceptor fate commitment	GO:0001752	36	0.074
regulation of response to stress	GO:0080134	200	0.074
regulation of actin polymerization or depolymerization	GO:0008064	27	0.073	Mouse
regulation of cell cycle process	GO:0010564	181	0.071
dna templated transcription initiation	GO:0006352	25	0.070
positive regulation of cell development	GO:0010720	61	0.069
skeletal muscle fiber development	GO:0048741	3	0.069	Zebrafish
negative regulation of cell development	GO:0010721	62	0.068	Fly
branch fusion open tracheal system	GO:0035147	17	0.067	Fly
tissue migration	GO:0090130	155	0.064
cellular response to endogenous stimulus	GO:0071495	80	0.064
taxis	GO:0042330	304	0.064
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.064
actomyosin structure organization	GO:0031032	56	0.063
macromolecular complex assembly	GO:0065003	256	0.061	Mouse
positive regulation of developmental process	GO:0051094	143	0.061
chaeta development	GO:0022416	97	0.060
regulation of mrna processing	GO:0050684	71	0.060
myofibril assembly	GO:0030239	36	0.060
morphogenesis of a branching structure	GO:0001763	45	0.060	Fly
telencephalon development	GO:0021537	2	0.059
regulation of protein polymerization	GO:0032271	28	0.059	Mouse
organelle assembly	GO:0070925	198	0.057
muscle fiber development	GO:0048747	12	0.057	Zebrafish
developmental maturation	GO:0021700	172	0.057
cellular pigmentation	GO:0033059	12	0.056
protein complex assembly	GO:0006461	200	0.055	Mouse
regulation of epithelial cell proliferation	GO:0050678	4	0.054
regulation of mrna splicing via spliceosome	GO:0048024	64	0.053
establishment of planar polarity	GO:0001736	87	0.053	Fly
adult chitin based cuticle pattern formation	GO:0035018	1	0.053	Fly
negative regulation of fusion cell fate specification	GO:0035157	2	0.053	Fly
regulation of peptidase activity	GO:0052547	39	0.052	Fly
positive regulation of cellular component biogenesis	GO:0044089	80	0.052	Mouse
erbb signaling pathway	GO:0038127	58	0.052	Fly
response to abiotic stimulus	GO:0009628	341	0.052
membrane organization	GO:0061024	112	0.051
reproductive system development	GO:0061458	74	0.051
proteolysis	GO:0006508	192	0.051	Fly
fusion cell fate specification	GO:0035156	4	0.048	Fly
wnt signaling pathway	GO:0016055	98	0.048
blastoderm segmentation	GO:0007350	159	0.048
cellular protein complex assembly	GO:0043623	71	0.048	Mouse
renal tubule morphogenesis	GO:0061333	44	0.048
regulation of cellular component size	GO:0032535	98	0.048	Mouse
positive regulation of programmed cell death	GO:0043068	62	0.046
neurological system process	GO:0050877	358	0.046
regulation of cell cycle	GO:0051726	291	0.046
chromosome organization	GO:0051276	360	0.046
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.043
regulation of axonogenesis	GO:0050770	32	0.043
regulation of cellular protein metabolic process	GO:0032268	243	0.043	Fly
regulation of organ growth	GO:0046620	42	0.043	Fly
regulation of intracellular signal transduction	GO:1902531	236	0.043	Fly
response to organic substance	GO:0010033	284	0.043
garland nephrocyte differentiation	GO:0061321	3	0.042
regulation of actin cytoskeleton organization	GO:0032956	42	0.042	Mouse Fly
cell type specific apoptotic process	GO:0097285	38	0.042
negative regulation of cell death	GO:0060548	81	0.042
imaginal disc pattern formation	GO:0007447	91	0.042
positive regulation of cellular amine metabolic process	GO:0033240	0	0.042
regulation of membrane potential	GO:0042391	35	0.041
digestive tract morphogenesis	GO:0048546	127	0.040
dna metabolic process	GO:0006259	227	0.040
spinal cord development	GO:0021510	1	0.039
digestive tract development	GO:0048565	149	0.039
body morphogenesis	GO:0010171	2	0.039
ventral furrow formation	GO:0007370	17	0.038
central nervous system neuron differentiation	GO:0021953	8	0.038
regulation of cellular ketone metabolic process	GO:0010565	3	0.038
regulation of mitotic cell cycle	GO:0007346	190	0.038
neuronal stem cell division	GO:0036445	35	0.037
embryo development ending in birth or egg hatching	GO:0009792	152	0.037
neuron migration	GO:0001764	5	0.037
regulation of protein modification process	GO:0031399	112	0.036
negative regulation of developmental growth	GO:0048640	64	0.036	Fly
wing disc pattern formation	GO:0035222	66	0.036
regulation of mitosis	GO:0007088	56	0.036
posttranscriptional regulation of gene expression	GO:0010608	145	0.035
mesoderm development	GO:0007498	78	0.034
determination of muscle attachment site	GO:0016204	7	0.034
negative regulation of cell cycle	GO:0045786	116	0.034
morphogenesis of embryonic epithelium	GO:0016331	94	0.033	Fly
embryonic heart tube development	GO:0035050	22	0.033
determination of bilateral symmetry	GO:0009855	13	0.033
regulation of epithelial cell differentiation	GO:0030856	4	0.033
organic acid metabolic process	GO:0006082	103	0.033
actin filament bundle organization	GO:0061572	28	0.033	Fly
negative regulation of axon extension	GO:0030517	3	0.032
sperm individualization	GO:0007291	48	0.032
antennal morphogenesis	GO:0048800	14	0.032
regulation of wound healing	GO:0061041	13	0.032
compound eye photoreceptor development	GO:0042051	78	0.032
regulation of nuclear division	GO:0051783	58	0.031
positive regulation of cell cycle	GO:0045787	43	0.031
positive regulation of cell death	GO:0010942	69	0.031
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.031
imaginal disc derived wing vein specification	GO:0007474	48	0.030
chemotaxis	GO:0006935	249	0.030
axon development	GO:0061564	297	0.030
negative regulation of cell cycle process	GO:0010948	109	0.029
striated muscle myosin thick filament assembly	GO:0071688	3	0.029
positive regulation of cell communication	GO:0010647	250	0.029	Fly
hippo signaling	GO:0035329	20	0.029	Fly
leg disc development	GO:0035218	92	0.029
sensory perception of mechanical stimulus	GO:0050954	72	0.029
positive regulation of catalytic activity	GO:0043085	118	0.029	Fly
regulation of cell cycle phase transition	GO:1901987	130	0.029
regulation of cellular amine metabolic process	GO:0033238	3	0.028
ameboidal type cell migration	GO:0001667	151	0.028
renal system process	GO:0003014	12	0.028
positive regulation of notch signaling pathway	GO:0045747	34	0.028	Fly
cellular protein modification process	GO:0006464	438	0.028
response to ionizing radiation	GO:0010212	32	0.027
gastrulation involving germ band extension	GO:0010004	36	0.027
multicellular organism growth	GO:0035264	46	0.027
positive regulation of cytoskeleton organization	GO:0051495	21	0.027	Mouse
regulation of compound eye cone cell fate specification	GO:0042682	4	0.027
regulation of sequestering of calcium ion	GO:0051282	3	0.027
vesicle mediated transport	GO:0016192	381	0.027
protein dna complex subunit organization	GO:0071824	86	0.026
epithelial cell proliferation	GO:0050673	15	0.026
regulation of rna splicing	GO:0043484	69	0.026
negative regulation of apoptotic process	GO:0043066	63	0.026
regulation of neuron differentiation	GO:0045664	103	0.026
lipid metabolic process	GO:0006629	121	0.026
renal filtration cell differentiation	GO:0061318	12	0.025
cellular response to chemical stimulus	GO:0070887	199	0.025
organ growth	GO:0035265	56	0.025	Fly
cell recognition	GO:0008037	102	0.025	Worm
camera type eye morphogenesis	GO:0048593	2	0.025
r8 cell fate commitment	GO:0007460	6	0.025
regulation of nervous system development	GO:0051960	248	0.024	Fly
negative regulation of neuron differentiation	GO:0045665	16	0.024
mrna processing	GO:0006397	104	0.024
phagocytosis	GO:0006909	215	0.024
regulation of neuron projection development	GO:0010975	69	0.024
negative regulation of cellular component organization	GO:0051129	108	0.024
positive regulation of actin filament polymerization	GO:0030838	11	0.024	Mouse
cell fate commitment involved in pattern specification	GO:0060581	31	0.024
male courtship behavior veined wing vibration	GO:0016545	21	0.023
rna splicing	GO:0008380	83	0.023
mapk cascade	GO:0000165	107	0.023	Mouse
r7 cell differentiation	GO:0045466	43	0.023
regulation of hydrolase activity	GO:0051336	97	0.023	Fly
cell projection assembly	GO:0030031	94	0.023
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.023
limb development	GO:0060173	1	0.023
regulation of protein metabolic process	GO:0051246	256	0.023	Fly
regulation of lipid metabolic process	GO:0019216	15	0.022
specification of symmetry	GO:0009799	13	0.022
hemopoiesis	GO:0030097	46	0.022
protein dna complex assembly	GO:0065004	63	0.022
positive regulation of cellular protein metabolic process	GO:0032270	118	0.022	Fly
stem cell maintenance	GO:0019827	67	0.021
neuron fate commitment	GO:0048663	50	0.021
regulation of phosphate metabolic process	GO:0019220	210	0.021
connective tissue development	GO:0061448	3	0.021
positive regulation of proteolysis	GO:0045862	52	0.021	Fly
photoreceptor cell axon guidance	GO:0072499	23	0.021
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.021
eggshell chorion assembly	GO:0007306	66	0.021	Fly
negative regulation of cell division	GO:0051782	17	0.021
negative regulation of cell fate specification	GO:0009996	15	0.020	Fly
regulation of protein phosphorylation	GO:0001932	64	0.020
adherens junction assembly	GO:0034333	11	0.020
rna splicing via transesterification reactions	GO:0000375	73	0.020
regulation of actin filament based process	GO:0032970	42	0.019	Mouse Fly
positive regulation of molecular function	GO:0044093	136	0.019	Fly
forebrain development	GO:0030900	2	0.019
cardioblast cell fate commitment	GO:0042684	14	0.019
cellular lipid metabolic process	GO:0044255	83	0.019
neuron recognition	GO:0008038	101	0.019	Worm
dorsal ventral pattern formation	GO:0009953	133	0.019
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.019	Fly
endocytosis	GO:0006897	310	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
protein polymerization	GO:0051258	42	0.018	Mouse
regulation of catalytic activity	GO:0050790	185	0.018	Fly
cellular catabolic process	GO:0044248	372	0.018
organonitrogen compound biosynthetic process	GO:1901566	117	0.018
positive regulation of cellular component organization	GO:0051130	156	0.017	Mouse
embryonic hindgut morphogenesis	GO:0048619	48	0.017
positive regulation of hydrolase activity	GO:0051345	78	0.017	Fly
extracellular matrix organization	GO:0030198	32	0.017
peptidyl tyrosine modification	GO:0018212	24	0.017
regulation of mrna metabolic process	GO:1903311	72	0.017
intracellular transport	GO:0046907	228	0.017
sensory organ boundary specification	GO:0008052	22	0.017
protein transport	GO:0015031	155	0.017
synaptic transmission	GO:0007268	288	0.017
neuroepithelial cell differentiation	GO:0060563	6	0.017
embryonic organ morphogenesis	GO:0048562	5	0.017
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	20	0.016
protein localization	GO:0008104	284	0.016
regulation of cell projection organization	GO:0031344	92	0.016
oocyte differentiation	GO:0009994	145	0.016
myoblast proliferation	GO:0051450	3	0.016
immune system development	GO:0002520	57	0.016
regulation of response to external stimulus	GO:0032101	115	0.016
compound eye cone cell differentiation	GO:0042675	13	0.016
single organismal cell cell adhesion	GO:0016337	45	0.016	Fly
regulation of endopeptidase activity	GO:0052548	36	0.016	Fly
negative regulation of organelle organization	GO:0010639	56	0.016
negative regulation of notch signaling pathway	GO:0045746	41	0.016
neuromuscular junction development	GO:0007528	149	0.015
ovarian follicle cell migration	GO:0007297	121	0.015
negative regulation of smoothened signaling pathway	GO:0045879	16	0.015
response to wounding	GO:0009611	94	0.015	Fly
regulation of developmental pigmentation	GO:0048070	24	0.015
mitotic nuclear division	GO:0007067	213	0.015
single organism membrane organization	GO:0044802	93	0.015
negative regulation of organ growth	GO:0046621	15	0.015	Fly
catabolic process	GO:0009056	409	0.015
neuron apoptotic process	GO:0051402	17	0.014
single organism nuclear import	GO:1902593	51	0.014
ion transport	GO:0006811	145	0.014
negative regulation of mitotic cell cycle	GO:0045930	109	0.014
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.014
intracellular signal transduction	GO:0035556	300	0.014	Mouse Fly
germ cell migration	GO:0008354	43	0.014
reproductive behavior	GO:0019098	122	0.014
regulation of transport	GO:0051049	181	0.014	Mouse
establishment of nucleus localization	GO:0040023	26	0.014
retina development in camera type eye	GO:0060041	4	0.014
regulation of cell division	GO:0051302	72	0.014
response to organonitrogen compound	GO:0010243	75	0.014
cellular ketone metabolic process	GO:0042180	24	0.014
cell maturation	GO:0048469	144	0.013
positive regulation of protein polymerization	GO:0032273	14	0.013	Mouse
apoptotic process involved in development	GO:1902742	20	0.013
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.013
wound healing	GO:0042060	75	0.013	Fly
positive regulation of wound healing	GO:0090303	12	0.013
developmental growth involved in morphogenesis	GO:0060560	65	0.013
positive regulation of organelle organization	GO:0010638	65	0.013	Mouse
single organism intracellular transport	GO:1902582	207	0.013
regulation of immune system process	GO:0002682	176	0.013
regulation of sequence specific dna binding transcription factor activity	GO:0051090	12	0.013
protein phosphorylation	GO:0006468	169	0.013
single organism cellular localization	GO:1902580	180	0.013
protein targeting	GO:0006605	64	0.013
alternative mrna splicing via spliceosome	GO:0000380	60	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012

sns disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.069
	musculoskeletal system disease	DOID:17	0	0.066

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