| protein modification by small protein conjugation or removal | GO:0070647 | 106 | 0.777 | |
| rna processing | GO:0006396 | 147 | 0.754 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 73 | 0.706 | |
| cellular protein catabolic process | GO:0044257 | 83 | 0.637 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 54 | 0.621 | |
| rna splicing via transesterification reactions | GO:0000375 | 73 | 0.606 | |
| phosphorylation | GO:0016310 | 294 | 0.583 | |
| protein catabolic process | GO:0030163 | 101 | 0.558 | |
| rna splicing | GO:0008380 | 83 | 0.553 | |
| regulation of mrna processing | GO:0050684 | 71 | 0.510 | |
| proteolysis | GO:0006508 | 192 | 0.510 | |
| spermatid differentiation | GO:0048515 | 114 | 0.498 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.486 | |
| cellular catabolic process | GO:0044248 | 372 | 0.477 | |
| catabolic process | GO:0009056 | 409 | 0.455 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.405 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.394 | |
| protein modification by small protein conjugation | GO:0032446 | 79 | 0.378 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 79 | 0.372 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.370 | |
| modification dependent protein catabolic process | GO:0019941 | 78 | 0.348 | |
| mrna metabolic process | GO:0016071 | 124 | 0.346 | |
| mrna splicing via spliceosome | GO:0000398 | 73 | 0.337 | |
| mrna processing | GO:0006397 | 104 | 0.327 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.326 | |
| spermatogenesis | GO:0007283 | 200 | 0.318 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 37 | 0.310 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.303 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.301 | |
| protein ubiquitination | GO:0016567 | 70 | 0.283 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.270 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.267 | |
| regulation of growth | GO:0040008 | 233 | 0.246 | |
| organelle fission | GO:0048285 | 340 | 0.226 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.213 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.207 | |
| regulation of protein catabolic process | GO:0042176 | 55 | 0.198 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.198 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.198 | |
| chromatin organization | GO:0006325 | 207 | 0.198 | Human |
| regulation of mrna splicing via spliceosome | GO:0048024 | 64 | 0.177 | |
| regulation of mrna metabolic process | GO:1903311 | 72 | 0.176 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.174 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.164 | |
| regulation of rna splicing | GO:0043484 | 69 | 0.161 | |
| response to organic substance | GO:0010033 | 284 | 0.145 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.144 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 83 | 0.143 | |
| aging | GO:0007568 | 143 | 0.143 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 44 | 0.143 | |
| protein dna complex subunit organization | GO:0071824 | 86 | 0.139 | |
| cell division | GO:0051301 | 248 | 0.139 | |
| protein modification process | GO:0036211 | 438 | 0.137 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.136 | |
| regulation of localization | GO:0032879 | 275 | 0.134 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 39 | 0.130 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.129 | |
| meiotic cell cycle | GO:0051321 | 171 | 0.126 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.125 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.124 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.124 | |
| regulation of phosphorylation | GO:0042325 | 147 | 0.122 | |
| chromosome organization | GO:0051276 | 360 | 0.121 | Human |
| vesicle mediated transport | GO:0016192 | 381 | 0.118 | |
| chromatin assembly or disassembly | GO:0006333 | 52 | 0.117 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 19 | 0.117 | |
| nucleosome organization | GO:0034728 | 59 | 0.116 | |
| developmental maturation | GO:0021700 | 172 | 0.115 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.111 | |
| nuclear division | GO:0000280 | 332 | 0.104 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 60 | 0.102 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.097 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.090 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.084 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.083 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.083 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.082 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.082 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.075 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.072 | |
| apoptotic process | GO:0006915 | 159 | 0.069 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.069 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 256 | 0.067 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 20 | 0.067 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.066 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.065 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.065 | |
| spermatid development | GO:0007286 | 98 | 0.064 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.064 | |
| protein k48 linked ubiquitination | GO:0070936 | 3 | 0.059 | Human |
| signal transduction by phosphorylation | GO:0023014 | 107 | 0.057 | |
| protein complex assembly | GO:0006461 | 200 | 0.055 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.055 | |
| protein modification by small protein removal | GO:0070646 | 28 | 0.055 | |
| translation | GO:0006412 | 69 | 0.054 | |
| male gamete generation | GO:0048232 | 201 | 0.054 | |
| cell maturation | GO:0048469 | 144 | 0.052 | |
| localization of cell | GO:0051674 | 257 | 0.052 | |
| negative regulation of nervous system development | GO:0051961 | 92 | 0.052 | |
| response to alcohol | GO:0097305 | 95 | 0.049 | |
| mapk cascade | GO:0000165 | 107 | 0.049 | |
| positive regulation of catabolic process | GO:0009896 | 105 | 0.045 | |
| negative regulation of multicellular organismal process | GO:0051241 | 142 | 0.045 | |
| endocytosis | GO:0006897 | 310 | 0.043 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 24 | 0.043 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.043 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.043 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.042 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.041 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.040 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.040 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.040 | |
| single organism biosynthetic process | GO:0044711 | 206 | 0.040 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.040 | |
| stem cell differentiation | GO:0048863 | 117 | 0.040 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.039 | |
| regulation of molecular function | GO:0065009 | 217 | 0.038 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.038 | |
| regulation of cellular protein catabolic process | GO:1903362 | 44 | 0.038 | |
| response to organic cyclic compound | GO:0014070 | 89 | 0.038 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.037 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.037 | |
| protein localization | GO:0008104 | 284 | 0.037 | |
| response to endogenous stimulus | GO:0009719 | 119 | 0.036 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.036 | |
| death | GO:0016265 | 284 | 0.036 | |
| mesenchymal cell differentiation | GO:0048762 | 1 | 0.036 | |
| positive regulation of cell proliferation | GO:0008284 | 47 | 0.035 | |
| cellular protein modification process | GO:0006464 | 438 | 0.035 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 24 | 0.035 | |
| cell death | GO:0008219 | 279 | 0.034 | |
| regulation of synapse structure and activity | GO:0050803 | 128 | 0.034 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.033 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.033 | |
| larval development | GO:0002164 | 104 | 0.033 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.033 | |
| negative regulation of cellular component organization | GO:0051129 | 108 | 0.033 | |
| positive regulation of cellular catabolic process | GO:0031331 | 95 | 0.033 | |
| regulation of metaphase anaphase transition of cell cycle | GO:1902099 | 26 | 0.032 | |
| appendage development | GO:0048736 | 401 | 0.032 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.032 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.032 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.031 | |
| positive regulation of protein catabolic process | GO:0045732 | 34 | 0.030 | |
| regulation of cytoplasmic transport | GO:1903649 | 47 | 0.030 | |
| compound eye photoreceptor cell differentiation | GO:0001751 | 140 | 0.030 | |
| regulation of meiosis | GO:0040020 | 3 | 0.030 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.030 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.030 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.029 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 151 | 0.029 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.029 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 60 | 0.028 | |
| cell motility | GO:0048870 | 251 | 0.028 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.028 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.028 | |
| regulation of cell death | GO:0010941 | 173 | 0.027 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.027 | |
| nucleus organization | GO:0006997 | 45 | 0.027 | |
| regulation of protein stability | GO:0031647 | 43 | 0.027 | |
| body morphogenesis | GO:0010171 | 2 | 0.027 | |
| eye development | GO:0001654 | 323 | 0.027 | |
| regulation of protein complex assembly | GO:0043254 | 42 | 0.026 | |
| protein phosphorylation | GO:0006468 | 169 | 0.026 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.026 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.026 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.026 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 103 | 0.026 | |
| rna 3 end processing | GO:0031123 | 45 | 0.026 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.025 | |
| meiotic nuclear division | GO:0007126 | 151 | 0.025 | |
| regulation of neurogenesis | GO:0050767 | 158 | 0.025 | |
| regulation of mapk cascade | GO:0043408 | 92 | 0.025 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.024 | |
| ubiquitin homeostasis | GO:0010992 | 1 | 0.024 | |
| multicellular organismal aging | GO:0010259 | 140 | 0.024 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.023 | |
| muscle organ development | GO:0007517 | 127 | 0.023 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.023 | |
| organelle assembly | GO:0070925 | 198 | 0.023 | |
| germarium derived egg chamber formation | GO:0007293 | 101 | 0.022 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.022 | |
| response to other organism | GO:0051707 | 293 | 0.022 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.022 | |
| cellular protein localization | GO:0034613 | 160 | 0.021 | |
| chromatin modification | GO:0016568 | 147 | 0.021 | Human |
| growth | GO:0040007 | 359 | 0.021 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 119 | 0.021 | |
| reproductive system development | GO:0061458 | 74 | 0.020 | |
| positive regulation of phosphorylation | GO:0042327 | 87 | 0.020 | |
| regulation of nuclear division | GO:0051783 | 58 | 0.020 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.020 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.020 | |
| regulation of locomotion | GO:0040012 | 42 | 0.020 | |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.020 | |
| response to nitrogen compound | GO:1901698 | 90 | 0.019 | |
| leg disc morphogenesis | GO:0007478 | 80 | 0.019 | |
| ncrna metabolic process | GO:0034660 | 43 | 0.019 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.019 | |
| cell aging | GO:0007569 | 2 | 0.019 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 116 | 0.019 | |
| stem cell division | GO:0017145 | 69 | 0.019 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.019 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.019 | |
| small gtpase mediated signal transduction | GO:0007264 | 88 | 0.018 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.018 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.018 | |
| chromosome segregation | GO:0007059 | 157 | 0.018 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.018 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.017 | |
| central nervous system development | GO:0007417 | 201 | 0.017 | |
| positive regulation of lipid metabolic process | GO:0045834 | 4 | 0.017 | |
| ras protein signal transduction | GO:0007265 | 88 | 0.017 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.017 | |
| defense response | GO:0006952 | 300 | 0.017 | |
| negative regulation of translation | GO:0017148 | 28 | 0.017 | |
| response to nutrient levels | GO:0031667 | 114 | 0.017 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.017 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.017 | |
| microtubule organizing center organization | GO:0031023 | 168 | 0.017 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 174 | 0.017 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.016 | |
| regulation of protein localization | GO:0032880 | 76 | 0.016 | |
| negative regulation of cellular catabolic process | GO:0031330 | 34 | 0.016 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.016 | |
| epithelial cell development | GO:0002064 | 274 | 0.016 | |
| neuron projection guidance | GO:0097485 | 241 | 0.016 | |
| positive regulation of mrna processing | GO:0050685 | 4 | 0.016 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.016 | |
| dna metabolic process | GO:0006259 | 227 | 0.016 | |
| regulation of cellular localization | GO:0060341 | 136 | 0.016 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.015 | |
| regulation of protein phosphorylation | GO:0001932 | 64 | 0.015 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.015 | |
| regulation of transport | GO:0051049 | 181 | 0.015 | |
| ovarian follicle cell development | GO:0030707 | 248 | 0.015 | |
| protein processing | GO:0016485 | 68 | 0.015 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.014 | |
| oocyte differentiation | GO:0009994 | 145 | 0.014 | |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.014 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.014 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.014 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.014 | |
| regulation of cell growth | GO:0001558 | 43 | 0.014 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.014 | |
| spliceosomal snrnp assembly | GO:0000387 | 2 | 0.014 | |
| regulation of cell division | GO:0051302 | 72 | 0.014 | |
| stem cell development | GO:0048864 | 79 | 0.014 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.014 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.014 | |
| regionalization | GO:0003002 | 416 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.013 | |
| regulation of neuron differentiation | GO:0045664 | 103 | 0.013 | |
| nucleosome assembly | GO:0006334 | 35 | 0.013 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.013 | |
| positive regulation of cell cycle process | GO:0090068 | 28 | 0.013 | |
| protein transport | GO:0015031 | 155 | 0.013 | |
| response to extracellular stimulus | GO:0009991 | 116 | 0.013 | |
| programmed cell death | GO:0012501 | 257 | 0.013 | |
| negative regulation of neuroblast proliferation | GO:0007406 | 27 | 0.013 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.013 | |
| negative regulation of neurogenesis | GO:0050768 | 53 | 0.013 | |
| intracellular protein transport | GO:0006886 | 104 | 0.013 | |
| nuclear envelope organization | GO:0006998 | 7 | 0.013 | |
| positive regulation of cell death | GO:0010942 | 69 | 0.013 | |
| positive regulation of cell cycle | GO:0045787 | 43 | 0.013 | |
| head development | GO:0060322 | 135 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.013 | |
| centrosome organization | GO:0051297 | 163 | 0.013 | |
| telencephalon development | GO:0021537 | 2 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 110 | 0.012 | |
| carbohydrate metabolic process | GO:0005975 | 82 | 0.012 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.012 | |
| secretion by cell | GO:0032940 | 101 | 0.012 | |
| mitotic sister chromatid segregation | GO:0000070 | 87 | 0.012 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 36 | 0.012 | |
| regulation of sister chromatid segregation | GO:0033045 | 28 | 0.012 | |
| protein dna complex assembly | GO:0065004 | 63 | 0.012 | |
| synapse assembly | GO:0007416 | 143 | 0.012 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.012 | |
| mitotic cell cycle checkpoint | GO:0007093 | 88 | 0.011 | |
| nucleotide metabolic process | GO:0009117 | 161 | 0.011 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.011 | |
| ovarian follicle cell migration | GO:0007297 | 121 | 0.011 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 63 | 0.011 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.011 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.011 | |
| nuclear transport | GO:0051169 | 72 | 0.011 | |
| trna processing | GO:0008033 | 3 | 0.011 | |
| chromatin assembly | GO:0031497 | 48 | 0.011 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.011 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.011 | |
| immune system process | GO:0002376 | 347 | 0.011 | |
| ameboidal type cell migration | GO:0001667 | 151 | 0.011 | |
| imaginal disc derived wing margin morphogenesis | GO:0008587 | 41 | 0.011 | |
| phagocytosis | GO:0006909 | 215 | 0.011 | |
| regulation of transferase activity | GO:0051338 | 58 | 0.011 | |
| segmentation | GO:0035282 | 207 | 0.011 | |
| camera type eye development | GO:0043010 | 4 | 0.011 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.010 | |
| axon development | GO:0061564 | 297 | 0.010 | |
| cell migration | GO:0016477 | 238 | 0.010 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 45 | 0.010 | |
| sex differentiation | GO:0007548 | 81 | 0.010 | |
| positive regulation of growth | GO:0045927 | 75 | 0.010 | |
| regulation of cellular component movement | GO:0051270 | 42 | 0.010 | |
