IMP: Integrative Multi-species Prediction

Drosophila melanogaster

145 known processes

hppy (Dmel_CG7097)

happyhour

(Aliases: MAP4K3,Dmel\CG7097,CG7097,GLK/KHS1,anon-WO0153538.68)

Entrez: 37203
FLYBASE: FBgn0034421
UniProtKB: A1ZBH8
UniProtKB: A1ZBH7

Process Predictions
Disease Predictions

hppy biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of intracellular signal transduction	GO:1902531	236	0.542
regulation of immune system process	GO:0002682	176	0.473
regulation of growth	GO:0040008	233	0.463
lipid metabolic process	GO:0006629	121	0.445
developmental growth	GO:0048589	280	0.420
death	GO:0016265	284	0.409
negative regulation of response to stimulus	GO:0048585	258	0.346
negative regulation of signaling	GO:0023057	219	0.321
negative regulation of signal transduction	GO:0009968	206	0.318
cellular protein modification process	GO:0006464	438	0.305
regulation of organ growth	GO:0046620	42	0.305
appendage development	GO:0048736	401	0.302
cellular ketone metabolic process	GO:0042180	24	0.275
regulation of response to stress	GO:0080134	200	0.272
multi organism behavior	GO:0051705	175	0.272
negative regulation of cell communication	GO:0010648	223	0.270
growth	GO:0040007	359	0.262
negative regulation of cellular metabolic process	GO:0031324	382	0.253
regulation of cellular amino acid metabolic process	GO:0006521	0	0.232
cell cycle phase transition	GO:0044770	140	0.215
tor signaling	GO:0031929	32	0.210
positive regulation of developmental growth	GO:0048639	62	0.203
regulation of developmental growth	GO:0048638	174	0.203
regulation of nervous system development	GO:0051960	248	0.201
response to nutrient levels	GO:0031667	114	0.200
regulation of cellular amine metabolic process	GO:0033238	3	0.199
protein modification process	GO:0036211	438	0.192
protein phosphorylation	GO:0006468	169	0.190
small molecule metabolic process	GO:0044281	305	0.181
cellular amino acid metabolic process	GO:0006520	61	0.169
positive regulation of response to stimulus	GO:0048584	323	0.159
ion transmembrane transport	GO:0034220	122	0.150
positive regulation of cell size	GO:0045793	21	0.147
signal transduction by phosphorylation	GO:0023014	107	0.144
intracellular signal transduction	GO:0035556	300	0.143
peptidyl threonine phosphorylation	GO:0018107	2	0.140
regulation of cellular ketone metabolic process	GO:0010565	3	0.140
positive regulation of growth	GO:0045927	75	0.136
purine nucleoside metabolic process	GO:0042278	127	0.130
cellular response to chemical stimulus	GO:0070887	199	0.130
cellular amine metabolic process	GO:0044106	12	0.128
positive regulation of developmental process	GO:0051094	143	0.128
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.128
vesicle mediated transport	GO:0016192	381	0.128	Mouse
cellular response to starvation	GO:0009267	61	0.125
cellular response to organic substance	GO:0071310	132	0.121
regionalization	GO:0003002	416	0.115
positive regulation of macromolecule metabolic process	GO:0010604	405	0.115	Human
single organism catabolic process	GO:0044712	228	0.110
multicellular organismal aging	GO:0010259	140	0.107
regulation of multicellular organism growth	GO:0040014	40	0.107
endocytosis	GO:0006897	310	0.107
actin filament based process	GO:0030029	220	0.107
negative regulation of synapse assembly	GO:0051964	39	0.104
chemical homeostasis	GO:0048878	92	0.102
reproductive behavior	GO:0019098	122	0.099
programmed cell death	GO:0012501	257	0.098
carboxylic acid metabolic process	GO:0019752	92	0.097
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.096
homeostatic process	GO:0042592	199	0.096
response to other organism	GO:0051707	293	0.096
regulation of anatomical structure size	GO:0090066	163	0.092
cellular response to external stimulus	GO:0071496	66	0.091
oxoacid metabolic process	GO:0043436	103	0.090
regulation of cellular component biogenesis	GO:0044087	201	0.090
imaginal disc derived appendage development	GO:0048737	399	0.089
intracellular transport	GO:0046907	228	0.088
organic cyclic compound catabolic process	GO:1901361	168	0.085
imaginal disc derived wing vein specification	GO:0007474	48	0.083
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.083
regulation of cell death	GO:0010941	173	0.080
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.079
actin cytoskeleton organization	GO:0030036	206	0.079
cell death	GO:0008219	279	0.079
immune response	GO:0006955	246	0.078
post embryonic appendage morphogenesis	GO:0035120	385	0.076
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.075
regulation of molecular function	GO:0065009	217	0.074	Human
immune system process	GO:0002376	347	0.074
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.074
positive regulation of cell communication	GO:0010647	250	0.073
peptidyl amino acid modification	GO:0018193	105	0.073	Human
adult behavior	GO:0030534	137	0.073
positive regulation of signal transduction	GO:0009967	223	0.071
response to organic substance	GO:0010033	284	0.069
negative regulation of gene expression	GO:0010629	387	0.069
immune response regulating signaling pathway	GO:0002764	2	0.069
cholesterol homeostasis	GO:0042632	3	0.068
peptide metabolic process	GO:0006518	80	0.068
purine nucleotide catabolic process	GO:0006195	109	0.067
cellular catabolic process	GO:0044248	372	0.066
gtp metabolic process	GO:0046039	72	0.065
nucleoside catabolic process	GO:0009164	112	0.065
establishment of localization in cell	GO:0051649	402	0.063	Mouse
regulation of cell cycle	GO:0051726	291	0.063
negative regulation of developmental growth	GO:0048640	64	0.063
erbb signaling pathway	GO:0038127	58	0.063
organophosphate metabolic process	GO:0019637	195	0.063
cell proliferation	GO:0008283	299	0.062	Human
microtubule based transport	GO:0010970	42	0.062
organic acid metabolic process	GO:0006082	103	0.060
positive regulation of rna metabolic process	GO:0051254	271	0.060
regulation of multicellular organismal development	GO:2000026	414	0.060
regulation of epithelial cell proliferation	GO:0050678	4	0.059
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.059
positive regulation of signaling	GO:0023056	243	0.059
cellular response to dna damage stimulus	GO:0006974	223	0.058
nucleoside triphosphate metabolic process	GO:0009141	120	0.058
multicellular organism growth	GO:0035264	46	0.057
amine metabolic process	GO:0009308	12	0.057
regulation of apoptotic process	GO:0042981	130	0.057
positive regulation of transcription dna templated	GO:0045893	266	0.056
regulation of response to extracellular stimulus	GO:0032104	18	0.056
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.055
autophagic vacuole assembly	GO:0000045	2	0.054
regulation of imaginal disc growth	GO:0045570	26	0.054
organelle assembly	GO:0070925	198	0.054
small gtpase mediated signal transduction	GO:0007264	88	0.053
regulation of cellular protein metabolic process	GO:0032268	243	0.053	Human
positive regulation of cellular amine metabolic process	GO:0033240	0	0.053
regulation of synapse structure and activity	GO:0050803	128	0.051
pigmentation	GO:0043473	75	0.050
organic substance transport	GO:0071702	257	0.050
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.049
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.049
appendage morphogenesis	GO:0035107	397	0.049
organelle fission	GO:0048285	340	0.049
cellular response to nutrient levels	GO:0031669	62	0.049
mitotic cell cycle phase transition	GO:0044772	138	0.049
regulation of nucleotide catabolic process	GO:0030811	48	0.049
negative regulation of kinase activity	GO:0033673	16	0.049
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.048
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.048
ion transport	GO:0006811	145	0.048
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.047
regulation of erbb signaling pathway	GO:1901184	42	0.047
regulation of synapse organization	GO:0050807	110	0.046
single organism biosynthetic process	GO:0044711	206	0.046
positive regulation of cellular biosynthetic process	GO:0031328	316	0.046
response to alcohol	GO:0097305	95	0.045
regulation of macroautophagy	GO:0016241	15	0.045
imaginal disc growth	GO:0007446	37	0.045
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.044
chromatin organization	GO:0006325	207	0.044
purine ribonucleoside metabolic process	GO:0046128	127	0.042
regulation of cellular catabolic process	GO:0031329	157	0.042
response to extracellular stimulus	GO:0009991	116	0.042
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.042
regulation of gtpase activity	GO:0043087	44	0.042
negative regulation of intracellular signal transduction	GO:1902532	57	0.042
phosphorylation	GO:0016310	294	0.041
regulation of nucleoside metabolic process	GO:0009118	50	0.041
positive regulation of multicellular organismal process	GO:0051240	143	0.041
regulation of epidermal growth factor activated receptor activity	GO:0007176	4	0.040
immune response activating signal transduction	GO:0002757	2	0.040
regulation of neurogenesis	GO:0050767	158	0.040
hippo signaling	GO:0035329	20	0.040
regulation of cellular response to stress	GO:0080135	89	0.040
regulation of anatomical structure morphogenesis	GO:0022603	242	0.039
response to biotic stimulus	GO:0009607	294	0.039
defense response	GO:0006952	300	0.039
organic substance catabolic process	GO:1901575	308	0.039
positive regulation of phosphate metabolic process	GO:0045937	139	0.039
aromatic compound catabolic process	GO:0019439	166	0.039
negative regulation of programmed cell death	GO:0043069	72	0.038
cation transport	GO:0006812	110	0.038
imaginal disc derived wing morphogenesis	GO:0007476	337	0.038
regulation of cellular component size	GO:0032535	98	0.038
actin filament organization	GO:0007015	126	0.037
purine nucleoside catabolic process	GO:0006152	112	0.037
cellular nitrogen compound catabolic process	GO:0044270	165	0.037
regulation of programmed cell death	GO:0043067	152	0.036
chromosome organization	GO:0051276	360	0.036
dna metabolic process	GO:0006259	227	0.036
positive regulation of intracellular signal transduction	GO:1902533	116	0.036
regulation of organelle organization	GO:0033043	196	0.035
regulation of cellular localization	GO:0060341	136	0.035
regulation of transport	GO:0051049	181	0.035
cell growth	GO:0016049	108	0.035
determination of adult lifespan	GO:0008340	137	0.035
cellular lipid metabolic process	GO:0044255	83	0.035
purine containing compound catabolic process	GO:0072523	112	0.035
response to external biotic stimulus	GO:0043207	293	0.034
synapse assembly	GO:0007416	143	0.034
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.034
negative regulation of apoptotic process	GO:0043066	63	0.034
apoptotic process	GO:0006915	159	0.034
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.034
positive regulation of gene expression	GO:0010628	290	0.034
protein complex assembly	GO:0006461	200	0.034
regulation of phosphorylation	GO:0042325	147	0.033
mapk cascade	GO:0000165	107	0.033
macroautophagy	GO:0016236	42	0.033
ras protein signal transduction	GO:0007265	88	0.033
nucleobase containing compound catabolic process	GO:0034655	165	0.032
phagocytosis	GO:0006909	215	0.032
wing disc morphogenesis	GO:0007472	344	0.032
positive regulation of cellular response to insulin stimulus	GO:1900078	4	0.032
notch signaling pathway	GO:0007219	120	0.032
innate immune response activating signal transduction	GO:0002758	2	0.030
glycosyl compound catabolic process	GO:1901658	112	0.030
ribonucleotide metabolic process	GO:0009259	145	0.030
regulation of cell proliferation	GO:0042127	163	0.030
nucleoside triphosphate catabolic process	GO:0009143	108	0.030
heterochromatin organization	GO:0070828	25	0.030
heterocycle catabolic process	GO:0046700	166	0.030
somatic muscle development	GO:0007525	66	0.030
response to abiotic stimulus	GO:0009628	341	0.030	Human
regulation of phosphorus metabolic process	GO:0051174	210	0.030
cellular homeostasis	GO:0019725	80	0.030
negative regulation of rna metabolic process	GO:0051253	251	0.029
negative regulation of cellular component organization	GO:0051129	108	0.029
single organism intracellular transport	GO:1902582	207	0.029
ribose phosphate metabolic process	GO:0019693	145	0.029
regulation of defense response	GO:0031347	102	0.029
nucleoside phosphate catabolic process	GO:1901292	110	0.029
gene silencing	GO:0016458	138	0.028
biological adhesion	GO:0022610	138	0.028
positive regulation of multicellular organism growth	GO:0040018	21	0.028
rubidium ion transport	GO:0035826	1	0.028
negative regulation of protein tyrosine kinase activity	GO:0061099	5	0.028
regulation of mitotic cell cycle	GO:0007346	190	0.028
spindle organization	GO:0007051	253	0.028
compound eye photoreceptor development	GO:0042051	78	0.028
negative regulation of growth	GO:0045926	84	0.028
negative regulation of phosphatidylinositol 3 kinase signaling	GO:0014067	4	0.027
phosphatidylinositol mediated signaling	GO:0048015	4	0.027
erk1 and erk2 cascade	GO:0070371	39	0.027
chromatin remodeling	GO:0006338	72	0.027
neuromuscular junction development	GO:0007528	149	0.026
organonitrogen compound metabolic process	GO:1901564	318	0.026
positive regulation of protein metabolic process	GO:0051247	128	0.026	Human
developmental cell growth	GO:0048588	52	0.025
organonitrogen compound catabolic process	GO:1901565	128	0.025
multi multicellular organism process	GO:0044706	123	0.025
translation	GO:0006412	69	0.025
regulation of response to nutrient levels	GO:0032107	18	0.025
cellular protein catabolic process	GO:0044257	83	0.025
negative regulation of cell death	GO:0060548	81	0.025
cell cycle checkpoint	GO:0000075	95	0.025
regulation of phosphatase activity	GO:0010921	3	0.025
multi organism reproductive behavior	GO:0044705	121	0.024
establishment of organelle localization	GO:0051656	122	0.024	Mouse
regulation of gene silencing	GO:0060968	63	0.024
triglyceride biosynthetic process	GO:0019432	2	0.024
negative regulation of protein metabolic process	GO:0051248	85	0.024
organophosphate catabolic process	GO:0046434	112	0.024
rac protein signal transduction	GO:0016601	3	0.024
organ growth	GO:0035265	56	0.024
protein modification by small protein conjugation or removal	GO:0070647	106	0.024
regulation of purine nucleotide catabolic process	GO:0033121	48	0.023
positive regulation of lipid catabolic process	GO:0050996	1	0.023
macromolecular complex assembly	GO:0065003	256	0.023
regulation of rac protein signal transduction	GO:0035020	3	0.023
histolysis	GO:0007559	102	0.023
regulation of hydrolase activity	GO:0051336	97	0.023
positive regulation of rna biosynthetic process	GO:1902680	266	0.023
mitotic sister chromatid separation	GO:0051306	30	0.023
regulation of phosphate metabolic process	GO:0019220	210	0.023
cellular macromolecule catabolic process	GO:0044265	136	0.022
regulation of catalytic activity	GO:0050790	185	0.022	Human
response to endogenous stimulus	GO:0009719	119	0.022
regulation of cell division	GO:0051302	72	0.022
locomotory behavior	GO:0007626	176	0.022
regulation of cytoplasmic transport	GO:1903649	47	0.022
head development	GO:0060322	135	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.022
salivary gland cell autophagic cell death	GO:0035071	83	0.022
single organism behavior	GO:0044708	391	0.022
regulation of immune response	GO:0050776	118	0.022
axon cargo transport	GO:0008088	29	0.022
regulation of cell size	GO:0008361	63	0.022
entry into diapause	GO:0055115	1	0.022
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.022
nucleoside metabolic process	GO:0009116	127	0.022
response to growth factor	GO:0070848	31	0.022
ribonucleoside catabolic process	GO:0042454	112	0.021
purine ribonucleoside catabolic process	GO:0046130	112	0.021
negative regulation of transferase activity	GO:0051348	18	0.021
positive regulation of cellular component organization	GO:0051130	156	0.021
nucleotide catabolic process	GO:0009166	109	0.021
salivary gland histolysis	GO:0035070	88	0.021
positive regulation of molecular function	GO:0044093	136	0.020	Human
regulation of vesicle mediated transport	GO:0060627	59	0.020
positive regulation of cellular protein metabolic process	GO:0032270	118	0.020	Human
regulation of localization	GO:0032879	275	0.020
negative regulation of cellular biosynthetic process	GO:0031327	277	0.020
regulation of catabolic process	GO:0009894	170	0.020
regulation of peptidyl tyrosine phosphorylation	GO:0050730	10	0.020
response to starvation	GO:0042594	97	0.020
regulation of cell cycle phase transition	GO:1901987	130	0.019
regulation of synapse assembly	GO:0051963	94	0.019
regulation of insulin receptor signaling pathway	GO:0046626	17	0.019
modification dependent macromolecule catabolic process	GO:0043632	79	0.019
regulation of notch signaling pathway	GO:0008593	100	0.019
peptidyl threonine modification	GO:0018210	3	0.019
chromosome segregation	GO:0007059	157	0.019
positive regulation of cell death	GO:0010942	69	0.019
regulation of imaginal disc derived wing size	GO:0044719	20	0.019
negative regulation of transcription dna templated	GO:0045892	237	0.019
ribonucleotide catabolic process	GO:0009261	109	0.019
regulation of gtp catabolic process	GO:0033124	44	0.018
negative regulation of photoreceptor cell differentiation	GO:0046533	8	0.018
tissue homeostasis	GO:0001894	36	0.018
regulation of translation	GO:0006417	56	0.018
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.018
regulation of cell differentiation	GO:0045595	302	0.018
regulation of ras protein signal transduction	GO:0046578	93	0.018
negative regulation of erbb signaling pathway	GO:1901185	29	0.018
synaptic growth at neuromuscular junction	GO:0051124	119	0.018
regulation of mapk cascade	GO:0043408	92	0.018
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.018
cellular response to endogenous stimulus	GO:0071495	80	0.017
nuclear division	GO:0000280	332	0.017
wnt signaling pathway	GO:0016055	98	0.017
striated muscle tissue development	GO:0014706	27	0.017
autophagic cell death	GO:0048102	83	0.017
response to bacterium	GO:0009617	198	0.017
body morphogenesis	GO:0010171	2	0.017
macromolecule catabolic process	GO:0009057	161	0.017
regulation of protein modification process	GO:0031399	112	0.017	Human
protein catabolic process	GO:0030163	101	0.017
aging	GO:0007568	143	0.017
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.017
proteolysis	GO:0006508	192	0.017
tube development	GO:0035295	244	0.017
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.016
nuclear transcribed mrna catabolic process	GO:0000956	24	0.016
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.016
torc1 signaling	GO:0038202	12	0.016
activation of innate immune response	GO:0002218	4	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.016
positive regulation of organ growth	GO:0046622	12	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
positive regulation of biosynthetic process	GO:0009891	316	0.016
cell adhesion	GO:0007155	136	0.016
response to oxygen containing compound	GO:1901700	200	0.016
negative regulation of peptidyl tyrosine phosphorylation	GO:0050732	6	0.016
regulation of cell cycle process	GO:0010564	181	0.016
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.015
carbohydrate derivative catabolic process	GO:1901136	118	0.015
tissue death	GO:0016271	102	0.015
transcription from rna polymerase ii promoter	GO:0006366	368	0.015
nucleobase containing small molecule metabolic process	GO:0055086	174	0.015
gastrulation	GO:0007369	70	0.015
response to oxidative stress	GO:0006979	86	0.015
er nucleus signaling pathway	GO:0006984	9	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
metal ion transport	GO:0030001	74	0.015
positive regulation of immune response	GO:0050778	63	0.015
jak stat cascade	GO:0007259	49	0.015
purine ribonucleotide catabolic process	GO:0009154	109	0.015
inositol lipid mediated signaling	GO:0048017	4	0.014
posttranscriptional regulation of gene expression	GO:0010608	145	0.014
anatomical structure homeostasis	GO:0060249	97	0.014
pattern recognition receptor signaling pathway	GO:0002221	2	0.014
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.014
developmental programmed cell death	GO:0010623	138	0.014
negative regulation of multicellular organismal process	GO:0051241	142	0.014
regulation of cellular response to insulin stimulus	GO:1900076	17	0.014
synaptic vesicle localization	GO:0097479	53	0.014
inorganic ion transmembrane transport	GO:0098660	73	0.014
larval development	GO:0002164	104	0.014
negative regulation of cellular protein metabolic process	GO:0032269	85	0.014
protein maturation	GO:0051604	71	0.014
transmembrane transport	GO:0055085	139	0.013
instar larval development	GO:0002168	55	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
negative regulation of notch signaling pathway	GO:0045746	41	0.013
cytokinesis	GO:0000910	90	0.013
regulation of cell projection organization	GO:0031344	92	0.013
regulation of neuron projection development	GO:0010975	69	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.013
cytoskeleton dependent intracellular transport	GO:0030705	44	0.013
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.013
regulation of autophagy	GO:0010506	62	0.013
negative regulation of mapk cascade	GO:0043409	23	0.013
response to copper ion	GO:0046688	4	0.013
ion homeostasis	GO:0050801	55	0.013
secretion by cell	GO:0032940	101	0.013
secretion	GO:0046903	109	0.013
r8 cell fate specification	GO:0045464	5	0.013
regulation of protein metabolic process	GO:0051246	256	0.013	Human
negative regulation of phosphorus metabolic process	GO:0010563	45	0.013
limb development	GO:0060173	1	0.013
cellular response to extracellular stimulus	GO:0031668	64	0.013
cell motility	GO:0048870	251	0.013
decapentaplegic signaling pathway	GO:0008101	19	0.012
multicellular organismal homeostasis	GO:0048871	41	0.012
negative regulation of epithelial cell proliferation	GO:0050680	4	0.012
cell division	GO:0051301	248	0.012
limb morphogenesis	GO:0035108	1	0.012
histone modification	GO:0016570	106	0.012
circadian behavior	GO:0048512	76	0.012
negative regulation of receptor activity	GO:2000272	3	0.012
positive regulation of transport	GO:0051050	92	0.012
negative regulation of catalytic activity	GO:0043086	42	0.012
cellular response to molecule of bacterial origin	GO:0071219	3	0.012
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.012
regulation of response to external stimulus	GO:0032101	115	0.012
regulation of protein import into nucleus	GO:0042306	28	0.012
ubiquitin dependent protein catabolic process	GO:0006511	78	0.012
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.012
protein modification by small protein removal	GO:0070646	28	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
necrotic cell death	GO:0070265	1	0.011
eye development	GO:0001654	323	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
regulation of endocytosis	GO:0030100	37	0.011
tube morphogenesis	GO:0035239	191	0.011
lateral inhibition	GO:0046331	206	0.011
positive regulation of cellular component biogenesis	GO:0044089	80	0.011
forebrain development	GO:0030900	2	0.011
negative regulation of protein phosphorylation	GO:0001933	17	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.011
nucleotide metabolic process	GO:0009117	161	0.011
regulation of cellular response to oxidative stress	GO:1900407	4	0.011
negative regulation of immune response	GO:0050777	39	0.011
regulation of innate immune response	GO:0045088	71	0.011
regulation of response to oxidative stress	GO:1902882	4	0.011
localization of cell	GO:0051674	257	0.011
phosphatidylinositol 3 kinase signaling	GO:0014065	4	0.011
meiotic nuclear division	GO:0007126	151	0.011
rhythmic behavior	GO:0007622	76	0.011
positive regulation of insulin receptor signaling pathway	GO:0046628	3	0.011
proteasomal protein catabolic process	GO:0010498	59	0.011
positive regulation of protein modification process	GO:0031401	58	0.011	Human
regulation of hippo signaling	GO:0035330	14	0.011
imaginal disc pattern formation	GO:0007447	91	0.011
compound eye development	GO:0048749	307	0.011
negative regulation of cell differentiation	GO:0045596	143	0.011
negative regulation of cell proliferation	GO:0008285	69	0.011
hormone metabolic process	GO:0042445	33	0.011
sterol homeostasis	GO:0055092	4	0.011
cellular response to biotic stimulus	GO:0071216	4	0.010
regulation of nucleotide metabolic process	GO:0006140	62	0.010
endomembrane system organization	GO:0010256	119	0.010
regulation of synaptic transmission	GO:0050804	69	0.010
muscle structure development	GO:0061061	224	0.010
protein localization	GO:0008104	284	0.010
purine containing compound metabolic process	GO:0072521	155	0.010
maintenance of location	GO:0051235	73	0.010
regulation of decapentaplegic signaling pathway	GO:0090097	8	0.010
regulation of mitosis	GO:0007088	56	0.010
developmental pigmentation	GO:0048066	68	0.010

hppy disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.020
disease of cellular proliferation	DOID:14566	0.020
organ system cancer	DOID:0050686	0.018
disease of anatomical entity	DOID:7	0.018
cardiovascular system disease	DOID:1287	0.013
disease of metabolism	DOID:0014667	0.010
acquired metabolic disease	DOID:0060158	0.010

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