Drosophila melanogaster

37 known processes

eIF-2alpha (Dmel_CG9946)

eukaryotic translation Initiation Factor 2alpha

(Aliases: eIF2alpha,eIF-2,M(1)8e3-10,M(1)19-153,eIF2 alpha,CG9946,l(1)14Cf,eIF-2 alpha,Eif2alpha,elF2alpha,IF2A_DROME,eIF2-alpha,eIF2a,M(1)14C,eIF-2 a,l(1)19-153,Dmel\CG9946)

eIF-2alpha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic spindle organizationGO:00070522200.672
spindle organizationGO:00070512530.328
spindle elongationGO:0051231830.233
mitotic spindle elongationGO:0000022810.131
embryo development ending in birth or egg hatchingGO:00097921520.102
body morphogenesisGO:001017120.092
purine ribonucleoside metabolic processGO:00461281270.087
carbohydrate derivative metabolic processGO:19011352170.073
purine containing compound metabolic processGO:00725211550.070
positive regulation of macromolecule metabolic processGO:00106044050.066
establishment of localization in cellGO:00516494020.065
translational initiationGO:0006413110.061
organonitrogen compound metabolic processGO:19015643180.061
sex differentiationGO:0007548810.053
cellular response to chemical stimulusGO:00708871990.053
organelle localizationGO:00516401480.052
oocyte constructionGO:00073081120.051
positive regulation of protein metabolic processGO:00512471280.051
positive regulation of cellular biosynthetic processGO:00313283160.049
nucleobase containing small molecule metabolic processGO:00550861740.046
nucleoside metabolic processGO:00091161270.042
purine ribonucleoside triphosphate metabolic processGO:00092051190.041
regulation of protein metabolic processGO:00512462560.040
centrosome organizationGO:00512971630.040
small molecule metabolic processGO:00442813050.040
negative regulation of response to stimulusGO:00485852580.040
single organism cellular localizationGO:19025801800.037
regulation of translationGO:0006417560.036
rrna processingGO:000636430.036
single organism intracellular transportGO:19025822070.035
nucleoside triphosphate metabolic processGO:00091411200.033
nucleotide metabolic processGO:00091171610.030
larval developmentGO:00021641040.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.030
cellular response to organic substanceGO:00713101320.029
vesicle mediated transportGO:00161923810.029
negative regulation of macromolecule biosynthetic processGO:00105582700.028
positive regulation of nitrogen compound metabolic processGO:00511733540.028
organic substance transportGO:00717022570.027
positive regulation of macromolecule biosynthetic processGO:00105572830.026
cell maturationGO:00484691440.026
response to abiotic stimulusGO:00096283410.026
reproductive system developmentGO:0061458740.025
purine nucleoside triphosphate metabolic processGO:00091441190.025
positive regulation of biosynthetic processGO:00098913160.024
cytoplasmic transportGO:00164821300.024
positive regulation of gene expressionGO:00106282900.024
developmental maturationGO:00217001720.024
translational elongationGO:000641440.023
protein modification processGO:00362114380.023
cellular macromolecule localizationGO:00707272200.023
negative regulation of nitrogen compound metabolic processGO:00511722650.023
negative regulation of cellular biosynthetic processGO:00313272770.022
centrosome cycleGO:00070981370.022
jak stat cascadeGO:0007259490.021
chromosome organizationGO:00512763600.021
endocytosisGO:00068973100.021
negative regulation of gene expressionGO:00106293870.021
cell deathGO:00082192790.021
growthGO:00400073590.020
positive regulation of response to stimulusGO:00485843230.020
nucleoside phosphate metabolic processGO:00067531620.020
oocyte axis specificationGO:00073091080.020
phagocytosisGO:00069092150.020
endomembrane system organizationGO:00102561190.020
ribonucleoside catabolic processGO:00424541120.019
oocyte developmentGO:00485991240.019
establishment of protein localizationGO:00451841630.019
posttranscriptional regulation of gene expressionGO:00106081450.019
regulation of cell proliferationGO:00421271630.019
positive regulation of rna metabolic processGO:00512542710.019
protein transportGO:00150311550.018
translationGO:0006412690.018
cellular nitrogen compound catabolic processGO:00442701650.018
cellular catabolic processGO:00442483720.018
regulation of apoptotic processGO:00429811300.018
catabolic processGO:00090564090.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
regulation of intracellular signal transductionGO:19025312360.017
single organism membrane organizationGO:0044802930.017
regulation of multi organism processGO:00439001310.017
macromolecule catabolic processGO:00090571610.017
cytoplasmic translationGO:000218100.016
intracellular transportGO:00469072280.016
regulation of peptidase activityGO:0052547390.016
negative regulation of cellular metabolic processGO:00313243820.016
microtubule organizing center organizationGO:00310231680.016
positive regulation of signal transductionGO:00099672230.016
ribose phosphate metabolic processGO:00196931450.016
intracellular protein transportGO:00068861040.015
regulation of catalytic activityGO:00507901850.015
organic cyclic compound catabolic processGO:19013611680.015
negative regulation of signal transductionGO:00099682060.015
positive regulation of hydrolase activityGO:0051345780.015
immune system processGO:00023763470.015
meiotic cell cycleGO:00513211710.015
positive regulation of cell communicationGO:00106472500.015
positive regulation of catalytic activityGO:00430851180.015
aromatic compound catabolic processGO:00194391660.015
regulation of gene expression epigeneticGO:00400291280.014
response to oxidative stressGO:0006979860.014
eye developmentGO:00016543230.014
positive regulation of nucleobase containing compound metabolic processGO:00459353320.014
pigment metabolic processGO:0042440840.014
protein processingGO:0016485680.014
negative regulation of cellular protein metabolic processGO:0032269850.014
regulation of cellular protein metabolic processGO:00322682430.014
oocyte differentiationGO:00099941450.014
ribonucleoside metabolic processGO:00091191270.014
stem cell differentiationGO:00488631170.014
dna metabolic processGO:00062592270.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
deathGO:00162652840.013
mesenchymal cell differentiationGO:004876210.013
heterocycle catabolic processGO:00467001660.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
regulation of endopeptidase activityGO:0052548360.013
negative regulation of biosynthetic processGO:00098902770.013
protein catabolic processGO:00301631010.013
positive regulation of rna biosynthetic processGO:19026802660.013
organophosphate metabolic processGO:00196371950.013
cellular response to oxygen containing compoundGO:1901701790.012
nucleocytoplasmic transportGO:0006913720.012
rna splicingGO:0008380830.012
mrna processingGO:00063971040.012
positive regulation of cellular protein metabolic processGO:00322701180.012
response to oxygen containing compoundGO:19017002000.012
chemical homeostasisGO:0048878920.012
development of primary sexual characteristicsGO:0045137500.012
segmentationGO:00352822070.012
cellular protein localizationGO:00346131600.012
nucleoside monophosphate metabolic processGO:0009123520.012
response to oxygen levelsGO:0070482590.012
purine ribonucleotide metabolic processGO:00091501450.012
negative regulation of protein metabolic processGO:0051248850.012
cellular macromolecule catabolic processGO:00442651360.012
regionalizationGO:00030024160.012
regulation of phosphorus metabolic processGO:00511742100.012
cellular response to dna damage stimulusGO:00069742230.012
cellular protein modification processGO:00064644380.011
positive regulation of molecular functionGO:00440931360.011
response to external biotic stimulusGO:00432072930.011
response to decreased oxygen levelsGO:0036293580.011
positive regulation of phosphate metabolic processGO:00459371390.011
single organism biosynthetic processGO:00447112060.011
carboxylic acid metabolic processGO:0019752920.011
reproductive structure developmentGO:0048608740.011
cellular amino acid metabolic processGO:0006520610.011
negative regulation of signalingGO:00230572190.011
regulation of neuron apoptotic processGO:0043523160.011
neuron apoptotic processGO:0051402170.011
regulation of cellular amine metabolic processGO:003323830.011
spermatogenesisGO:00072832000.011
cellular amine metabolic processGO:0044106120.011
negative regulation of cell cycle phase transitionGO:19019881030.011
ribonucleotide metabolic processGO:00092591450.011
regulation of neuron deathGO:1901214260.011
rna localizationGO:00064031150.011
nucleobase containing compound catabolic processGO:00346551650.011
determination of adult lifespanGO:00083401370.011
positive regulation of reactive oxygen species metabolic processGO:200037900.010
axis specificationGO:00097981670.010
macromolecular complex assemblyGO:00650032560.010
transcription from rna polymerase ii promoterGO:00063663680.010
immune effector processGO:0002252980.010
positive regulation of signalingGO:00230562430.010
purine ribonucleoside monophosphate metabolic processGO:0009167500.010
cell proliferationGO:00082832990.010
intracellular signal transductionGO:00355563000.010
negative regulation of neuron deathGO:1901215180.010

eIF-2alpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023