Drosophila melanogaster

205 known processes

Gef64C (Dmel_CG32239)

Guanine nucleotide exchange factor GEF64C

(Aliases: EP3035,RhoGEF,RhoGEF64C,Dmel\CG32239,CG13710,GEF(64C),GEF,CG32239,CG13709,EP(3)3035,GEF64C)

Gef64C biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
aggressive behaviorGO:0002118630.407
imaginal disc derived appendage morphogenesisGO:00351143950.259
agingGO:00075681430.207
regulation of production of molecular mediator of immune responseGO:0002700440.197
negative regulation of cellular biosynthetic processGO:00313272770.187
axon developmentGO:00615642970.181
regulation of nervous system developmentGO:00519602480.170
imaginal disc derived wing morphogenesisGO:00074763370.153
central nervous system developmentGO:00074172010.146
appendage developmentGO:00487364010.146
biological adhesionGO:00226101380.143
Mouse
imaginal disc derived appendage developmentGO:00487373990.134
post embryonic appendage morphogenesisGO:00351203850.133
multi organism behaviorGO:00517051750.124
organonitrogen compound metabolic processGO:19015643180.123
gland developmentGO:00487321910.121
dendrite guidanceGO:0070983210.117
forebrain developmentGO:003090020.114
response to biotic stimulusGO:00096072940.107
regulation of cell differentiationGO:00455953020.103
Mouse
taxisGO:00423303040.100
cell deathGO:00082192790.098
Human
regulation of cell developmentGO:00602842150.089
Mouse
wing disc morphogenesisGO:00074723440.086
epithelial cell developmentGO:00020642740.085
determination of adult lifespanGO:00083401370.085
actin cytoskeleton organizationGO:00300362060.085
cellular catabolic processGO:00442483720.079
response to other organismGO:00517072930.077
response to starvationGO:0042594970.076
response to external biotic stimulusGO:00432072930.076
inter male aggressive behaviorGO:0002121600.071
humoral immune responseGO:00069591170.068
response to bacteriumGO:00096171980.068
regulation of immune system processGO:00026821760.067
negative regulation of response to stimulusGO:00485852580.067
intracellular signal transductionGO:00355563000.067
regulation of response to external stimulusGO:00321011150.065
negative regulation of developmental processGO:00510932010.065
peptide metabolic processGO:0006518800.064
regulation of catalytic activityGO:00507901850.063
antimicrobial humoral responseGO:0019730990.063
regulation of multicellular organismal developmentGO:20000264140.061
regulation of protein metabolic processGO:00512462560.061
olfactory learningGO:0008355560.057
protein modification processGO:00362114380.057
positive regulation of proteolysisGO:0045862520.056
epidermis developmentGO:0008544650.055
regulation of transcription from rna polymerase ii promoterGO:00063573780.055
response to extracellular stimulusGO:00099911160.054
deathGO:00162652840.052
Human
response to organic substanceGO:00100332840.051
columnar cuboidal epithelial cell developmentGO:00020662490.051
appendage morphogenesisGO:00351073970.050
antimicrobial peptide productionGO:0002775460.049
salivary gland developmentGO:00074311620.046
regulation of notch signaling pathwayGO:00085931000.046
positive regulation of catabolic processGO:00098961050.045
regulation of antimicrobial humoral responseGO:0002759500.045
neural precursor cell proliferationGO:0061351750.045
regulation of intracellular signal transductionGO:19025312360.044
transcription from rna polymerase ii promoterGO:00063663680.044
ras protein signal transductionGO:0007265880.043
negative regulation of cell differentiationGO:00455961430.043
cell migrationGO:00164772380.043
Mouse
actin filament based processGO:00300292200.042
single organism biosynthetic processGO:00447112060.042
morphogenesis of an epitheliumGO:00020092760.042
negative regulation of nervous system developmentGO:0051961920.041
organonitrogen compound biosynthetic processGO:19015661170.041
programmed cell deathGO:00125012570.039
Human
positive regulation of cellular biosynthetic processGO:00313283160.039
protein phosphorylationGO:00064681690.039
columnar cuboidal epithelial cell differentiationGO:00020652560.037
regulation of cell deathGO:00109411730.036
Human
small gtpase mediated signal transductionGO:0007264880.036
feeding behaviorGO:0007631500.035
negative regulation of signalingGO:00230572190.035
phosphorylationGO:00163102940.035
response to lipopolysaccharideGO:003249640.035
protein catabolic processGO:00301631010.034
telencephalon developmentGO:002153720.034
negative regulation of cellular metabolic processGO:00313243820.034
lipid metabolic processGO:00066291210.034
negative regulation of biosynthetic processGO:00098902770.034
epithelial cell differentiationGO:00308553220.033
regulation of lipid metabolic processGO:0019216150.033
muscle structure developmentGO:00610612240.032
tissue morphogenesisGO:00487292970.032
positive regulation of phosphate metabolic processGO:00459371390.032
long term memoryGO:0007616620.032
protein localizationGO:00081042840.032
ventral cord developmentGO:0007419160.031
response to nitrogen compoundGO:1901698900.031
axon guidanceGO:00074112330.031
skin developmentGO:0043588650.031
memoryGO:0007613940.031
negative regulation of cellular component organizationGO:00511291080.031
localization of cellGO:00516742570.031
Mouse
startle responseGO:0001964160.030
positive regulation of signal transductionGO:00099672230.030
negative regulation of growthGO:0045926840.030
peptide biosynthetic processGO:0043043420.030
positive regulation of developmental processGO:00510941430.030
Mouse
negative regulation of cell communicationGO:00106482230.029
response to ethanolGO:0045471590.029
regulation of localizationGO:00328792750.029
regulation of phosphorus metabolic processGO:00511742100.029
chemosensory behaviorGO:00076351060.029
chemotaxisGO:00069352490.029
regulation of epithelial cell differentiationGO:003085640.029
neuron fate commitmentGO:0048663500.028
regulation of ras protein signal transductionGO:0046578930.028
regulation of cellular amide metabolic processGO:0034248390.028
regulation of immune effector processGO:0002697520.028
cellular response to chemical stimulusGO:00708871990.027
Human
regulation of phosphate metabolic processGO:00192202100.027
positive regulation of macromolecule metabolic processGO:00106044050.027
axonogenesisGO:00074092900.027
response to organonitrogen compoundGO:0010243750.026
apoptotic processGO:00069151590.026
Human
small molecule metabolic processGO:00442813050.026
catabolic processGO:00090564090.026
tube developmentGO:00352952440.026
macromolecule catabolic processGO:00090571610.026
single organism behaviorGO:00447083910.026
positive regulation of catalytic activityGO:00430851180.025
positive regulation of cell migrationGO:003033520.025
head developmentGO:00603221350.025
negative regulation of immune system processGO:0002683500.025
regulation of multi organism processGO:00439001310.025
cell motilityGO:00488702510.025
Mouse
organic substance catabolic processGO:19015753080.024
establishment or maintenance of cell polarityGO:00071631670.024
single organism catabolic processGO:00447122280.024
phenol containing compound metabolic processGO:0018958570.023
positive regulation of cell communicationGO:00106472500.023
regulation of humoral immune responseGO:0002920510.023
regulation of molecular functionGO:00650092170.023
autophagyGO:00069141080.023
regulation of response to stressGO:00801342000.023
regulation of cellular component biogenesisGO:00440872010.023
negative regulation of notch signaling pathwayGO:0045746410.022
cellular protein modification processGO:00064644380.022
regulation of antimicrobial peptide biosynthetic processGO:0002805380.022
protein complex assemblyGO:00064612000.022
tissue migrationGO:00901301550.022
ovarian follicle cell developmentGO:00307072480.022
regulation of synapse organizationGO:00508071100.022
regulation of response to biotic stimulusGO:0002831630.022
organic substance transportGO:00717022570.022
cellular amide metabolic processGO:0043603800.022
ameboidal type cell migrationGO:00016671510.022
developmental programmed cell deathGO:00106231380.022
positive regulation of cellular protein metabolic processGO:00322701180.022
chemical homeostasisGO:0048878920.022
axon choice point recognitionGO:0016198260.022
morphogenesis of a branching epitheliumGO:0061138450.022
organ formationGO:0048645390.022
mating behaviorGO:00076171060.021
proteolysisGO:00065081920.021
steroid catabolic processGO:000670610.021
positive regulation of nitrogen compound metabolic processGO:00511733540.021
positive regulation of response to stimulusGO:00485843230.020
cellular response to nitrogen compoundGO:1901699510.020
endocytosisGO:00068973100.020
anatomical structure homeostasisGO:0060249970.020
cellular ketone metabolic processGO:0042180240.020
regulation of programmed cell deathGO:00430671520.020
Human
vesicle mediated transportGO:00161923810.020
gland morphogenesisGO:00226121450.020
regulation of proteolysisGO:0030162870.020
positive regulation of signalingGO:00230562430.020
cellular response to endogenous stimulusGO:0071495800.019
morphogenesis of a branching structureGO:0001763450.019
defense responseGO:00069523000.019
regulation of neuron differentiationGO:00456641030.019
regulation of cellular component sizeGO:0032535980.019
positive regulation of cellular catabolic processGO:0031331950.019
amide biosynthetic processGO:0043604420.019
phototransductionGO:0007602520.018
mushroom body developmentGO:0016319700.018
immune system processGO:00023763470.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
locomotory behaviorGO:00076261760.018
axon midline choice point recognitionGO:0016199260.018
branching morphogenesis of an epithelial tubeGO:0048754450.018
regulation of mapk cascadeGO:0043408920.018
respiratory system developmentGO:00605412130.018
positive regulation of rna metabolic processGO:00512542710.017
regulation of immune responseGO:00507761180.017
homeostatic processGO:00425921990.017
glial cell migrationGO:0008347310.017
response to abiotic stimulusGO:00096283410.017
Human
regulation of cellular catabolic processGO:00313291570.017
phagocytosisGO:00069092150.017
regulation of insulin receptor signaling pathwayGO:0046626170.017
negative regulation of protein metabolic processGO:0051248850.017
positive regulation of hydrolase activityGO:0051345780.017
response to nutrient levelsGO:00316671140.017
cell recognitionGO:00080371020.017
cellular homeostasisGO:0019725800.016
carboxylic acid metabolic processGO:0019752920.016
protein modification by small protein conjugation or removalGO:00706471060.016
convergent extensionGO:006002620.016
positive regulation of multicellular organismal processGO:00512401430.016
defense response to bacteriumGO:00427421780.016
positive regulation of phosphorus metabolic processGO:00105621390.016
olfactory behaviorGO:0042048970.016
androgen metabolic processGO:000820910.016
positive regulation of cellular component organizationGO:00511301560.016
Mouse
cellular macromolecule localizationGO:00707272200.016
mitotic nuclear divisionGO:00070672130.016
body morphogenesisGO:001017120.016
multicellular organismal agingGO:00102591400.016
cellular amino acid metabolic processGO:0006520610.016
immune effector processGO:0002252980.016
brain developmentGO:00074201200.016
cell proliferationGO:00082832990.016
positive regulation of cellular component biogenesisGO:0044089800.015
positive regulation of gtpase activityGO:0043547430.015
negative regulation of signal transductionGO:00099682060.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
regulation of cellular ketone metabolic processGO:001056530.015
intracellular transportGO:00469072280.015
response to light stimulusGO:00094161240.015
hindbrain developmentGO:003090220.015
regulation of cellular component movementGO:0051270420.015
camera type eye developmentGO:004301040.015
epithelial cell migrationGO:00106311480.015
r7 cell differentiationGO:0045466430.015
regulation of cellular amine metabolic processGO:003323830.015
single organism intracellular transportGO:19025822070.015
dna metabolic processGO:00062592270.015
positive regulation of gene expressionGO:00106282900.014
dendrite morphogenesisGO:00488131990.014
positive regulation of protein metabolic processGO:00512471280.014
regulation of cellular response to insulin stimulusGO:1900076170.014
regulation of growthGO:00400082330.014
response to organic cyclic compoundGO:0014070890.014
stem cell differentiationGO:00488631170.014
regulation of catabolic processGO:00098941700.014
mapk cascadeGO:00001651070.014
lamellipodium organizationGO:0097581210.014
photoreceptor cell axon guidanceGO:0072499230.014
reproductive behaviorGO:00190981220.014
regulation of embryonic developmentGO:0045995680.014
brain morphogenesisGO:0048854160.014
kidney developmentGO:000182230.014
rhythmic processGO:00485111060.013
dendrite developmentGO:00163582040.013
camera type eye morphogenesisGO:004859320.013
tube morphogenesisGO:00352391910.013
negative regulation of cell developmentGO:0010721620.013
neuron recognitionGO:00080381010.013
sensory perceptionGO:00076001960.013
response to oxidative stressGO:0006979860.013
Human
exocrine system developmentGO:00352721620.013
carbohydrate derivative metabolic processGO:19011352170.013
immune responseGO:00069552460.013
negative regulation of cellular protein metabolic processGO:0032269850.013
lateral inhibitionGO:00463312060.013
establishment of tissue polarityGO:0007164870.013
regulation of mitotic cell cycleGO:00073461900.012
cellular response to organonitrogen compoundGO:0071417360.012
single organism cell adhesionGO:0098602470.012
Mouse
extrinsic apoptotic signaling pathwayGO:009719110.012
negative regulation of response to external stimulusGO:0032102220.012
epidermal cell differentiationGO:0009913510.012
cellular response to ethanolGO:007136140.012
establishment of localization in cellGO:00516494020.012
estrogen metabolic processGO:000821010.012
male courtship behaviorGO:0008049630.012
negative regulation of phosphorylationGO:0042326350.012
macromolecular complex assemblyGO:00650032560.012
response to endogenous stimulusGO:00097191190.012
regulation of circadian rhythmGO:0042752490.012
cell cell signaling involved in cell fate commitmentGO:00451682100.012
retina development in camera type eyeGO:006004140.012
catechol containing compound metabolic processGO:0009712100.012
serotonin receptor signaling pathwayGO:000721050.012
regionalizationGO:00030024160.012
regulation of cell cycle processGO:00105641810.012
developmental maturationGO:00217001720.012
carbohydrate metabolic processGO:0005975820.012
negative regulation of defense responseGO:0031348350.012
positive regulation of organelle organizationGO:0010638650.012
regulation of transferase activityGO:0051338580.012
regulation of epithelial cell migration open tracheal systemGO:2000274110.012
developmental cell growthGO:0048588520.012
cellular response to biotic stimulusGO:007121640.012
regulation of protein transportGO:0051223570.012
positive regulation of transcription dna templatedGO:00458932660.012
secondary metabolic processGO:0019748750.012
regulation of cellular protein metabolic processGO:00322682430.012
lipid catabolic processGO:0016042210.012
central complex developmentGO:004803690.012
lipid biosynthetic processGO:0008610460.011
regulation of antibacterial peptide productionGO:0002786220.011
positive regulation of nucleoside metabolic processGO:0045979470.011
embryonic pattern specificationGO:00098801740.011
negative regulation of multicellular organismal processGO:00512411420.011
positive regulation of developmental growthGO:0048639620.011
regulation of cell cycleGO:00517262910.011
digestive system developmentGO:00551231490.011
negative regulation of cell deathGO:0060548810.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
male mating behaviorGO:0060179700.011
rac protein signal transductionGO:001660130.011
pigment metabolic processGO:0042440840.011
regulation of neuron apoptotic processGO:0043523160.011
purine containing compound metabolic processGO:00725211550.011
response to peptide hormoneGO:0043434290.011
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.011
epithelium migrationGO:00901321480.011
circadian rhythmGO:00076231050.011
cellular protein localizationGO:00346131600.011
cytoplasmic transportGO:00164821300.011
courtship behaviorGO:0007619680.011
regulation of defense responseGO:00313471020.011
histolysisGO:00075591020.011
single organism carbohydrate metabolic processGO:0044723720.010
dorsal ventral axon guidanceGO:003356320.010
response to peptideGO:1901652290.010
signal transduction by phosphorylationGO:00230141070.010
cell adhesionGO:00071551360.010
Mouse
oxoacid metabolic processGO:00434361030.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010
organophosphate metabolic processGO:00196371950.010
regulation of phosphorylationGO:00423251470.010
positive regulation of transportGO:0051050920.010
regulation of neurogenesisGO:00507671580.010
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
regulation of glial cell differentiationGO:004568510.010
hemocyte differentiationGO:0042386380.010

Gef64C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011