Drosophila melanogaster

60 known processes

hay (Dmel_CG8019)

haywire

(Aliases: DhXPB,DmXPB,DhR25,XPB,nc2,ERCC3,Xpb/hay,ms(3)nc2,CG8019,i50,TFIIH,hwr,Dmel\CG8019)

hay biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:0006281540.997
Human Yeast
cellular response to dna damage stimulusGO:00069742230.988
Human Yeast
meiotic cell cycleGO:00513211710.986
meiotic chromosome segregationGO:0045132590.985
meiotic cell cycle processGO:19030461320.956
meiotic nuclear divisionGO:00071261510.888
double strand break repairGO:0006302260.888
negative regulation of cell cycle phase transitionGO:19019881030.862
mitotic dna damage checkpointGO:0044773740.859
cell proliferationGO:00082832990.827
regulation of meiosisGO:004002030.780
chromosome segregationGO:00070591570.769
double strand break repair via synthesis dependent strand annealingGO:004500360.736
organelle fissionGO:00482853400.725
dna metabolic processGO:00062592270.697
Human Yeast Rat
regulation of cell cycle processGO:00105641810.689
Human
ribonucleoside monophosphate catabolic processGO:0009158390.681
Human Yeast Rat
negative regulation of cell cycleGO:00457861160.664
immune system processGO:00023763470.647
dna geometric changeGO:0032392160.627
Human Yeast Rat
nucleotide excision repairGO:000628980.595
Human Yeast
dna recombinationGO:0006310320.584
Yeast
mitotic cell cycle checkpointGO:0007093880.575
dna conformation changeGO:00711031050.562
Human Yeast Rat
mitotic cell cycle phase transitionGO:00447721380.546
Human
cell divisionGO:00513012480.497
negative regulation of mitotic cell cycleGO:00459301090.488
postreplication repairGO:000630120.484
cell cycle checkpointGO:0000075950.456
chromosome organizationGO:00512763600.421
meiosis iiGO:0007135230.418
carbohydrate derivative metabolic processGO:19011352170.416
Human Yeast Rat
programmed cell deathGO:00125012570.404
Human
regulation of cell cycleGO:00517262910.370
Human
regulation of cell divisionGO:0051302720.363
germarium derived egg chamber formationGO:00072931010.321
embryo development ending in birth or egg hatchingGO:00097921520.316
Worm
g2 dna damage checkpointGO:0031572690.293
dna damage checkpointGO:0000077780.291
regulation of nuclear divisionGO:0051783580.287
mrna metabolic processGO:00160711240.283
mitotic g2 m transition checkpointGO:0044818700.281
nucleobase containing compound catabolic processGO:00346551650.279
Human Yeast Rat
mitotic g2 dna damage checkpointGO:0007095690.266
sex differentiationGO:0007548810.263
immune responseGO:00069552460.243
development of primary sexual characteristicsGO:0045137500.240
recombinational repairGO:0000725130.239
regulation of mitotic cell cycle phase transitionGO:19019901300.235
Human
response to ionizing radiationGO:0010212320.233
dna double strand break processingGO:000072930.227
rna splicingGO:0008380830.224
dna biosynthetic processGO:0071897240.221
negative regulation of mitotic cell cycle phase transitionGO:19019911030.220
rna splicing via transesterification reactionsGO:0000375730.218
regulation of cell cycle phase transitionGO:19019871300.215
Human
protein modification processGO:00362114380.210
Human Yeast Rat
double strand break repair via homologous recombinationGO:0000724130.204
determination of adult lifespanGO:00083401370.200
response to abiotic stimulusGO:00096283410.200
organophosphate metabolic processGO:00196371950.197
Human Yeast Rat
purine ribonucleoside metabolic processGO:00461281270.190
Human Yeast Rat
centrosome cycleGO:00070981370.187
larval developmentGO:00021641040.180
single organism biosynthetic processGO:00447112060.180
purine nucleoside monophosphate catabolic processGO:0009128380.173
Human Yeast Rat
negative regulation of cell cycle processGO:00109481090.171
ribonucleoside catabolic processGO:00424541120.169
Human Yeast Rat
regulation of organelle organizationGO:00330431960.163
anterior posterior pattern specificationGO:00099521360.156
regulation of dna repairGO:000628250.148
mrna processingGO:00063971040.148
dna duplex unwindingGO:0032508160.147
Human Yeast Rat
oocyte constructionGO:00073081120.147
regulation of meiotic cell cycleGO:005144590.141
apoptotic processGO:00069151590.139
Human
cell cycle phase transitionGO:00447701400.138
Human
dna integrity checkpointGO:0031570810.135
germarium derived oocyte fate determinationGO:0007294260.132
reproductive structure developmentGO:0048608740.131
reproductive system developmentGO:0061458740.130
mitotic dna integrity checkpointGO:0044774750.129
carbohydrate derivative catabolic processGO:19011361180.126
Human Yeast Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353320.126
Human
non recombinational repairGO:000072670.124
gonad developmentGO:0008406500.123
aromatic compound catabolic processGO:00194391660.118
Human Yeast Rat
nucleoside monophosphate catabolic processGO:0009125390.117
Human Yeast Rat
positive regulation of cellular biosynthetic processGO:00313283160.111
Human
ribonucleoside triphosphate catabolic processGO:00092031080.109
Human Yeast Rat
negative regulation of mitotic sister chromatid separationGO:2000816130.107
atp metabolic processGO:0046034490.106
Human Yeast Rat
cellular protein modification processGO:00064644380.105
Human Yeast Rat
purine ribonucleoside catabolic processGO:00461301120.102
Human Yeast Rat
signal transduction in response to dna damageGO:004277030.100
genitalia developmentGO:0048806260.096
translesion synthesisGO:001998520.094
telomere maintenance via recombinationGO:000072210.092
nucleobase containing small molecule metabolic processGO:00550861740.092
Human Yeast Rat
multicellular organismal reproductive behaviorGO:00330571100.091
cellular amino acid metabolic processGO:0006520610.091
purine nucleotide catabolic processGO:00061951090.091
Human Yeast Rat
positive regulation of macromolecule biosynthetic processGO:00105572830.090
Human
negative regulation of cell divisionGO:0051782170.089
gene silencingGO:00164581380.089
regulation of response to dna damage stimulusGO:2001020230.088
endocytosisGO:00068973100.088
dna dependent dna replicationGO:0006261170.086
regionalizationGO:00030024160.085
nuclear divisionGO:00002803320.085
negative regulation of macromolecule biosynthetic processGO:00105582700.078
atp catabolic processGO:0006200380.078
Human Yeast Rat
dna replicationGO:0006260480.077
negative regulation of biosynthetic processGO:00098902770.076
response to other organismGO:00517072930.076
glycoprotein metabolic processGO:0009100410.075
meiosis iGO:0007127590.075
purine nucleoside triphosphate catabolic processGO:00091461080.074
Human Yeast Rat
protein maturationGO:0051604710.074
glycosyl compound catabolic processGO:19016581120.072
Human Yeast Rat
nucleoside triphosphate metabolic processGO:00091411200.072
Human Yeast Rat
oocyte differentiationGO:00099941450.069
carbohydrate derivative biosynthetic processGO:1901137850.068
axis specificationGO:00097981670.067
centrosome duplicationGO:00512981210.064
glycosyl compound metabolic processGO:19016571270.064
Human Yeast Rat
small molecule metabolic processGO:00442813050.062
Human Yeast Rat
cellular macromolecule catabolic processGO:00442651360.058
response to radiationGO:00093141550.058
ribose phosphate metabolic processGO:00196931450.057
Human Yeast Rat
ribonucleoside metabolic processGO:00091191270.056
Human Yeast Rat
lateral inhibitionGO:00463312060.056
negative regulation of nitrogen compound metabolic processGO:00511722650.056
purine nucleoside monophosphate metabolic processGO:0009126500.056
Human Yeast Rat
cellular catabolic processGO:00442483720.055
Human Yeast Rat
ribonucleotide catabolic processGO:00092611090.055
Human Yeast Rat
negative regulation of nucleobase containing compound metabolic processGO:00459342610.054
purine ribonucleoside monophosphate catabolic processGO:0009169380.054
Human Yeast Rat
purine nucleoside metabolic processGO:00422781270.053
Human Yeast Rat
glycoprotein biosynthetic processGO:0009101410.053
nucleoside phosphate catabolic processGO:19012921100.052
Human Yeast Rat
protein processingGO:0016485680.051
oocyte fate determinationGO:0030716270.050
segmentationGO:00352822070.049
positive regulation of rna metabolic processGO:00512542710.049
Human
proteolysisGO:00065081920.048
regulation of cell proliferationGO:00421271630.046
purine ribonucleotide catabolic processGO:00091541090.046
Human Yeast Rat
nucleoside triphosphate catabolic processGO:00091431080.045
Human Yeast Rat
single organism catabolic processGO:00447122280.044
Human Yeast Rat
female meiotic divisionGO:0007143700.044
organonitrogen compound metabolic processGO:19015643180.042
Human Yeast Rat
dna packagingGO:0006323910.042
carboxylic acid metabolic processGO:0019752920.041
purine ribonucleoside triphosphate catabolic processGO:00092071080.040
Human Yeast Rat
response to external biotic stimulusGO:00432072930.039
organophosphate catabolic processGO:00464341120.039
Human Yeast Rat
oocyte maturationGO:000155630.039
regulation of protein catabolic processGO:0042176550.038
ribonucleotide metabolic processGO:00092591450.038
Human Yeast Rat
spindle organizationGO:00070512530.037
growthGO:00400073590.037
cell cell signaling involved in cell fate commitmentGO:00451682100.037
protein complex biogenesisGO:00702712010.037
peptidyl amino acid modificationGO:00181931050.037
ribonucleoside monophosphate metabolic processGO:0009161510.037
Human Yeast Rat
tripartite regional subdivisionGO:00073511030.037
purine containing compound catabolic processGO:00725231120.036
Human Yeast Rat
cell deathGO:00082192790.036
Human
deathGO:00162652840.035
Human
humoral immune responseGO:00069591170.035
double strand break repair via nonhomologous end joiningGO:000630350.034
anterior posterior axis specificationGO:00099481090.034
oxoacid metabolic processGO:00434361030.034
positive regulation of signalingGO:00230562430.033
regulation of spindle organizationGO:0090224170.033
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.033
regulation of hemocyte proliferationGO:0035206370.032
purine nucleoside catabolic processGO:00061521120.032
Human Yeast Rat
chromosome condensationGO:0030261410.031
regulation of catalytic activityGO:00507901850.030
organic cyclic compound catabolic processGO:19013611680.030
Human Yeast Rat
positive regulation of nitrogen compound metabolic processGO:00511733540.030
Human
body morphogenesisGO:001017120.029
regulation of mitotic cell cycleGO:00073461900.029
Human
positive regulation of transcription dna templatedGO:00458932660.028
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.028
purine nucleoside triphosphate metabolic processGO:00091441190.027
Human Yeast Rat
dorsal ventral pattern formationGO:00099531330.027
response to biotic stimulusGO:00096072940.027
vesicle mediated transportGO:00161923810.027
anatomical structure homeostasisGO:0060249970.027
nucleoside catabolic processGO:00091641120.026
Human Yeast Rat
actin cytoskeleton organizationGO:00300362060.026
purine ribonucleoside triphosphate metabolic processGO:00092051190.026
Human Yeast Rat
regulation of catabolic processGO:00098941700.025
nucleoside phosphate metabolic processGO:00067531620.025
Human Yeast Rat
negative regulation of cellular component organizationGO:00511291080.025
organic substance catabolic processGO:19015753080.025
Human Yeast Rat
chromosome separationGO:0051304420.025
regulation of cellular catabolic processGO:00313291570.024
organonitrogen compound catabolic processGO:19015651280.024
Human Yeast Rat
catabolic processGO:00090564090.024
Human Yeast Rat
ribonucleoside triphosphate metabolic processGO:00091991190.024
Human Yeast Rat
multicellular organismal agingGO:00102591400.023
pigmentationGO:0043473750.023
negative regulation of cell deathGO:0060548810.022
negative regulation of organelle organizationGO:0010639560.022
negative regulation of gene expressionGO:00106293870.022
embryonic axis specificationGO:00005781070.022
agingGO:00075681430.021
modification dependent protein catabolic processGO:0019941780.021
organic acid metabolic processGO:00060821030.021
response to organic cyclic compoundGO:0014070890.021
dna synthesis involved in dna repairGO:000073150.021
defense responseGO:00069523000.021
protein glycosylationGO:0006486320.021
regulation of multi organism processGO:00439001310.021
response to light stimulusGO:00094161240.020
cellular macromolecule localizationGO:00707272200.020
cellular amide metabolic processGO:0043603800.020
positive regulation of biosynthetic processGO:00098913160.020
Human
negative regulation of sister chromatid segregationGO:0033046130.020
regulation of protein complex assemblyGO:0043254420.020
lipid metabolic processGO:00066291210.020
embryonic pattern specificationGO:00098801740.019
regulation of immune responseGO:00507761180.019
regulation of programmed cell deathGO:00430671520.019
Human
positive regulation of signal transductionGO:00099672230.019
meiosis ii cytokinesisGO:0007111110.019
nucleotide metabolic processGO:00091171610.019
Human Yeast Rat
regulation of phosphatase activityGO:001092130.019
telomere maintenanceGO:0000723210.018
regulation of immune system processGO:00026821760.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.018
regulation of cellular protein catabolic processGO:1903362440.018
purine nucleotide metabolic processGO:00061631460.018
Human Yeast Rat
macromolecular complex assemblyGO:00650032560.018
purine ribonucleoside monophosphate metabolic processGO:0009167500.018
Human Yeast Rat
negative regulation of dna dependent dna replicationGO:200010420.018
maintenance of locationGO:0051235730.017
immune effector processGO:0002252980.017
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.017
Human
positive regulation of immune responseGO:0050778630.017
establishment of protein localizationGO:00451841630.017
negative regulation of mitotic sister chromatid segregationGO:0033048130.017
regulation of double strand break repairGO:200077930.017
heterocycle catabolic processGO:00467001660.017
Human Yeast Rat
columnar cuboidal epithelial cell differentiationGO:00020652560.016
positive regulation of immune system processGO:0002684680.016
regulation of proteolysisGO:0030162870.016
spindle stabilizationGO:0043146140.016
imaginal disc derived appendage morphogenesisGO:00351143950.016
regulation of protein processingGO:0070613320.016
nucleoside monophosphate metabolic processGO:0009123520.015
Human Yeast Rat
cuticle developmentGO:0042335860.015
modification dependent macromolecule catabolic processGO:0043632790.015
protein catabolic processGO:00301631010.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
germarium derived oocyte differentiationGO:0030706290.015
cytokinesisGO:0000910900.015
regulation of innate immune responseGO:0045088710.015
negative regulation of chromosome segregationGO:0051985140.014
digestive tract morphogenesisGO:00485461270.014
oocyte developmentGO:00485991240.014
negative regulation of cellular metabolic processGO:00313243820.014
positive regulation of gene expressionGO:00106282900.014
Human
spindle checkpointGO:0031577110.014
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
Human
cell agingGO:000756920.013
amine metabolic processGO:0009308120.013
regulation of cellular ketone metabolic processGO:001056530.013
nucleotide catabolic processGO:00091661090.013
Human Yeast Rat
protein complex assemblyGO:00064612000.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
epidermis developmentGO:0008544650.013
Human
negative regulation of rna metabolic processGO:00512532510.013
innate immune responseGO:00450871440.013
actin filament based processGO:00300292200.012
organelle assemblyGO:00709251980.012
cellular response to ionizing radiationGO:0071479150.012
positive regulation of mapk cascadeGO:0043410630.012
negative regulation of gene expression epigeneticGO:0045814770.012
germarium derived female germ line cyst formationGO:0030727420.012
regulation of response to stressGO:00801342000.012
homeostatic processGO:00425921990.012
membrane organizationGO:00610241120.012
regulation of mitosisGO:0007088560.012
rna processingGO:00063961470.011
regulation of protein complex disassemblyGO:0043244290.011
hatchingGO:003518840.011
regulation of dna templated transcription elongationGO:0032784170.011
response to x rayGO:001016580.011
phagocytosisGO:00069092150.011
taxisGO:00423303040.011
cell maturationGO:00484691440.011
meiosis i cytokinesisGO:0007110120.011
positive regulation of response to stimulusGO:00485843230.011
purine ribonucleotide metabolic processGO:00091501450.011
Human Yeast Rat
wound healingGO:0042060750.011
anterior posterior axis specification embryoGO:00085951030.011
regulation of protein metabolic processGO:00512462560.011
mitotic spindle organizationGO:00070522200.011
ubiquitin dependent protein catabolic processGO:0006511780.011
protein dna complex subunit organizationGO:0071824860.010
Yeast
mrna splicing via spliceosomeGO:0000398730.010
divalent inorganic cation homeostasisGO:0072507290.010
positive regulation of phosphorus metabolic processGO:00105621390.010
male meiosis chromosome segregationGO:0007060100.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
regulation of mrna processingGO:0050684710.010
cellular nitrogen compound catabolic processGO:00442701650.010
Human Yeast Rat
regulation of dna recombinationGO:000001840.010
Yeast

hay disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013