Drosophila melanogaster

0 known processes

Spt-I (Dmel_CG4016)

Serine palmitoyltransferase subunit I

(Aliases: Dmel\CG4016,SPT-I,lcb1,l(2)SH2 1626,Spt1,l(2)SH1626,CG4016)

Spt-I biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein modification processGO:00064644380.230
transmembrane transportGO:00550851390.145
organic substance transportGO:00717022570.145
protein modification processGO:00362114380.119
deathGO:00162652840.093
endocytosisGO:00068973100.089
carbohydrate derivative biosynthetic processGO:1901137850.079
ion transportGO:00068111450.075
amino sugar metabolic processGO:0006040100.074
establishment of localization in cellGO:00516494020.060
vesicle mediated transportGO:00161923810.059
lateral inhibitionGO:00463312060.057
carbohydrate derivative metabolic processGO:19011352170.047
cellular protein localizationGO:00346131600.045
regulation of notch signaling pathwayGO:00085931000.045
epithelial cell differentiationGO:00308553220.045
membrane lipid metabolic processGO:0006643220.045
pigmentationGO:0043473750.044
protein transportGO:00150311550.043
programmed cell deathGO:00125012570.042
cell deathGO:00082192790.042
establishment of protein localizationGO:00451841630.042
protein localizationGO:00081042840.041
regulation of cell deathGO:00109411730.041
single organism intracellular transportGO:19025822070.039
single organism behaviorGO:00447083910.038
cellular macromolecule localizationGO:00707272200.038
cellular lipid metabolic processGO:0044255830.037
small molecule metabolic processGO:00442813050.036
developmental pigmentationGO:0048066680.036
proteolysisGO:00065081920.035
organonitrogen compound metabolic processGO:19015643180.035
cell motilityGO:00488702510.035
carbohydrate metabolic processGO:0005975820.035
retina development in camera type eyeGO:006004140.034
lipid biosynthetic processGO:0008610460.033
phagocytosisGO:00069092150.033
oxoacid metabolic processGO:00434361030.033
camera type eye developmentGO:004301040.033
anion transportGO:0006820410.032
nucleoside triphosphate metabolic processGO:00091411200.031
protein prenylationGO:001834230.030
purine ribonucleotide catabolic processGO:00091541090.030
single organism biosynthetic processGO:00447112060.030
regulation of apoptotic processGO:00429811300.030
neuromuscular junction developmentGO:00075281490.030
ion transmembrane transportGO:00342201220.029
organelle fusionGO:0048284460.028
ribonucleoside metabolic processGO:00091191270.028
immune system processGO:00023763470.027
ribonucleotide metabolic processGO:00092591450.027
catabolic processGO:00090564090.027
cellular ketone metabolic processGO:0042180240.027
peptidyl amino acid modificationGO:00181931050.027
positive regulation of cell communicationGO:00106472500.026
purine ribonucleoside metabolic processGO:00461281270.026
defense response to other organismGO:00985422250.026
response to biotic stimulusGO:00096072940.025
amino acid transportGO:0006865120.025
skeletal muscle fiber developmentGO:004874130.025
cellular ion homeostasisGO:0006873390.024
autophagyGO:00069141080.024
organonitrogen compound biosynthetic processGO:19015661170.024
intracellular protein transportGO:00068861040.024
response to external biotic stimulusGO:00432072930.024
single organism carbohydrate metabolic processGO:0044723720.023
cation homeostasisGO:0055080510.023
cytoplasmic transportGO:00164821300.022
single organism membrane fusionGO:0044801420.022
glycoprotein biosynthetic processGO:0009101410.022
lipid metabolic processGO:00066291210.022
secondary metabolic processGO:0019748750.022
neurological system processGO:00508773580.022
organic acid metabolic processGO:00060821030.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
glycoprotein metabolic processGO:0009100410.021
toxin metabolic processGO:000940420.021
cellular cation homeostasisGO:0030003380.021
single organism catabolic processGO:00447122280.021
purine containing compound transmembrane transportGO:007253050.021
positive regulation of signal transductionGO:00099672230.020
cation transportGO:00068121100.020
growthGO:00400073590.020
anion transmembrane transportGO:0098656260.020
positive regulation of response to stimulusGO:00485843230.020
nephron developmentGO:007200630.019
cell divisionGO:00513012480.019
cell migrationGO:00164772380.019
protein localization to organelleGO:0033365820.019
glycosyl compound catabolic processGO:19016581120.019
regulation of cell sizeGO:0008361630.019
eye developmentGO:00016543230.019
eye pigment biosynthetic processGO:0006726320.019
taxisGO:00423303040.019
response to lipopolysaccharideGO:003249640.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of cellular protein metabolic processGO:00322682430.019
cellular pigmentationGO:0033059120.019
cellular chemical homeostasisGO:0055082400.018
organic substance catabolic processGO:19015753080.018
regulation of cellular amine metabolic processGO:003323830.018
multicellular organismal agingGO:00102591400.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
ubiquitin dependent protein catabolic processGO:0006511780.018
membrane organizationGO:00610241120.018
synapse organizationGO:00508081960.018
positive regulation of signalingGO:00230562430.018
myotube cell developmentGO:001490430.018
membrane fusionGO:0061025420.018
single organism membrane organizationGO:0044802930.018
organonitrogen compound catabolic processGO:19015651280.018
regulation of catabolic processGO:00098941700.018
purine nucleotide metabolic processGO:00061631460.018
response to bacteriumGO:00096171980.018
notch signaling pathwayGO:00072191200.018
chemotaxisGO:00069352490.018
localization of cellGO:00516742570.018
body morphogenesisGO:001017120.017
regulation of catalytic activityGO:00507901850.017
protein maturationGO:0051604710.017
carboxylic acid metabolic processGO:0019752920.017
purine nucleotide catabolic processGO:00061951090.017
intracellular transportGO:00469072280.017
inorganic ion transmembrane transportGO:0098660730.017
cellular amino acid metabolic processGO:0006520610.017
apoptotic processGO:00069151590.017
endomembrane system organizationGO:00102561190.017
outflow tract morphogenesisGO:000315140.017
regionalizationGO:00030024160.016
single organism cellular localizationGO:19025801800.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
nitrogen compound transportGO:0071705850.016
divalent inorganic cation homeostasisGO:0072507290.016
forebrain developmentGO:003090020.016
organophosphate metabolic processGO:00196371950.016
negative regulation of calcium ion importGO:009028120.016
secretionGO:00469031090.016
regulation of molecular functionGO:00650092170.016
regulation of cellular ketone metabolic processGO:001056530.016
cellular response to chemical stimulusGO:00708871990.016
protein palmitoylationGO:001834520.016
regulation of programmed cell deathGO:00430671520.015
negative regulation of nervous system developmentGO:0051961920.015
positive regulation of macromolecule metabolic processGO:00106044050.015
cellular catabolic processGO:00442483720.015
aromatic compound catabolic processGO:00194391660.015
ribonucleoside catabolic processGO:00424541120.015
compound eye developmentGO:00487493070.015
response to other organismGO:00517072930.015
steroid catabolic processGO:000670610.015
defense responseGO:00069523000.015
phosphorylationGO:00163102940.015
carboxylic acid transportGO:0046942180.014
regulation of localizationGO:00328792750.014
cellular homeostasisGO:0019725800.014
pigment metabolic processGO:0042440840.014
purine containing compound catabolic processGO:00725231120.014
hippo signalingGO:0035329200.014
regulation of hydrolase activityGO:0051336970.014
pigment granule organizationGO:0048753120.014
metal ion transportGO:0030001740.014
regulation of anatomical structure sizeGO:00900661630.013
cortical cytoskeleton organizationGO:0030865290.013
kidney developmentGO:000182230.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
regulation of intracellular signal transductionGO:19025312360.013
anterograde synaptic vesicle transportGO:004849030.013
response to painGO:004826530.013
positive regulation of catalytic activityGO:00430851180.013
purine ribonucleoside catabolic processGO:00461301120.013
regulation of meiosisGO:004002030.013
positive regulation of cell motilityGO:200014730.013
metal ion homeostasisGO:0055065440.013
golgi organizationGO:0007030660.013
epithelial cell developmentGO:00020642740.013
neuron deathGO:0070997270.013
protein catabolic processGO:00301631010.013
ribosomal large subunit biogenesisGO:004227310.013
organic acid transportGO:0015849180.013
regulation of neuron deathGO:1901214260.013
positive regulation of molecular functionGO:00440931360.013
positive regulation of phosphorus metabolic processGO:00105621390.013
nucleoside phosphate catabolic processGO:19012921100.012
leg disc morphogenesisGO:0007478800.012
protein acylationGO:0043543420.012
nucleoside catabolic processGO:00091641120.012
biological adhesionGO:00226101380.012
defense response to bacteriumGO:00427421780.012
regulation of anatomical structure morphogenesisGO:00226032420.012
cellular divalent inorganic cation homeostasisGO:0072503230.012
regulation of cellular component sizeGO:0032535980.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
heterocycle catabolic processGO:00467001660.012
purine containing compound metabolic processGO:00725211550.012
macromolecule glycosylationGO:0043413320.012
regulation of growthGO:00400082330.012
xenobiotic catabolic processGO:004217810.012
telencephalon developmentGO:002153720.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
regulation of transportGO:00510491810.012
purine nucleoside catabolic processGO:00061521120.012
organic cyclic compound catabolic processGO:19013611680.012
ribonucleotide catabolic processGO:00092611090.012
positive regulation of cell deathGO:0010942690.012
pigment cell differentiationGO:005093130.012
nucleoside triphosphate catabolic processGO:00091431080.011
appendage morphogenesisGO:00351073970.011
actin filament based processGO:00300292200.011
substrate adhesion dependent cell spreadingGO:003444620.011
leg disc developmentGO:0035218920.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
liposaccharide metabolic processGO:190350980.011
actin cytoskeleton organizationGO:00300362060.011
eye pigment granule organizationGO:0008057120.011
embryonic morphogenesisGO:00485982060.011
imaginal disc derived appendage developmentGO:00487373990.011
organophosphate catabolic processGO:00464341120.011
protein processingGO:0016485680.011
nucleotide catabolic processGO:00091661090.011
digestive tract morphogenesisGO:00485461270.011
ribonucleoside monophosphate catabolic processGO:0009158390.011
protein glycosylationGO:0006486320.011
monocarboxylic acid transportGO:001571830.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
ocellus pigment metabolic processGO:0046158190.011
organelle membrane fusionGO:0090174160.011
synapse assemblyGO:00074161430.011
branched chain amino acid transportGO:001580330.011
response to organophosphorusGO:004668320.011
organelle fissionGO:00482853400.010
regulation of cellular localizationGO:00603411360.010
developmental growthGO:00485892800.010
cellular response to dna damage stimulusGO:00069742230.010
intracellular signal transductionGO:00355563000.010
glycosyl compound metabolic processGO:19016571270.010
mitotic nuclear divisionGO:00070672130.010
sensory organ morphogenesisGO:00905962600.010
cellular response to carbohydrate stimulusGO:007132240.010
divalent inorganic cation transportGO:0072511300.010
digestive tract developmentGO:00485651490.010
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
regulation of synapse structure and activityGO:00508031280.010

Spt-I disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
sensory system diseaseDOID:005015500.026
nervous system diseaseDOID:86300.026
eye diseaseDOID:561400.021
eye and adnexa diseaseDOID:149200.021
urinary system diseaseDOID:1800.013
kidney diseaseDOID:55700.013
renal tubular transport diseaseDOID:44700.013