IMP: Integrative Multi-species Prediction

Drosophila melanogaster

33 known processes

Nup54 (Dmel_CG8831)

Nucleoporin 54

(Aliases: nup54,CG8831,Dmel\CG8831)

Entrez: 36360
FLYBASE: FBgn0033737
UniProtKB: Q9V6B9

Process Predictions
Disease Predictions

Nup54 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
centrosome organization	GO:0051297	163	0.188
centrosome duplication	GO:0051298	121	0.151
cell proliferation	GO:0008283	299	0.130
organic substance transport	GO:0071702	257	0.107
centrosome cycle	GO:0007098	137	0.066
nuclear division	GO:0000280	332	0.066
protein localization	GO:0008104	284	0.064
chromatin organization	GO:0006325	207	0.055
regulation of organelle organization	GO:0033043	196	0.047
dna conformation change	GO:0071103	105	0.046
chromosome organization	GO:0051276	360	0.043
dna replication	GO:0006260	48	0.040
mitotic nuclear division	GO:0007067	213	0.038
single organism biosynthetic process	GO:0044711	206	0.036
cellular amino acid metabolic process	GO:0006520	61	0.034
small molecule metabolic process	GO:0044281	305	0.033
appendage development	GO:0048736	401	0.030
central nervous system development	GO:0007417	201	0.030
phagocytosis	GO:0006909	215	0.029
macromolecular complex assembly	GO:0065003	256	0.028
post embryonic appendage morphogenesis	GO:0035120	385	0.027
mrna processing	GO:0006397	104	0.027
nuclear transport	GO:0051169	72	0.027
chromatin modification	GO:0016568	147	0.027
wing disc morphogenesis	GO:0007472	344	0.027
organelle assembly	GO:0070925	198	0.027
imaginal disc derived appendage development	GO:0048737	399	0.027
negative regulation of signal transduction	GO:0009968	206	0.025
regulation of cell cycle	GO:0051726	291	0.025
negative regulation of response to stimulus	GO:0048585	258	0.025
respiratory system development	GO:0060541	213	0.025
dna metabolic process	GO:0006259	227	0.024
protein transport	GO:0015031	155	0.024
sensory perception	GO:0007600	196	0.024
regulation of cellular component biogenesis	GO:0044087	201	0.023
chromosome segregation	GO:0007059	157	0.023
organic cyclic compound catabolic process	GO:1901361	168	0.022
cellular component assembly involved in morphogenesis	GO:0010927	151	0.022
cell division	GO:0051301	248	0.022
cellular macromolecular complex assembly	GO:0034622	153	0.022
protein complex biogenesis	GO:0070271	201	0.021
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.021
establishment of localization in cell	GO:0051649	402	0.021
organelle fission	GO:0048285	340	0.020
microtubule organizing center organization	GO:0031023	168	0.019
single organism cellular localization	GO:1902580	180	0.019
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.019
positive regulation of cell cycle	GO:0045787	43	0.019
nucleus organization	GO:0006997	45	0.019
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.019
negative regulation of cellular metabolic process	GO:0031324	382	0.019
protein depolymerization	GO:0051261	31	0.019
nucleobase containing compound transport	GO:0015931	56	0.019
nucleoside monophosphate metabolic process	GO:0009123	52	0.018
regulation of molecular function	GO:0065009	217	0.018
establishment or maintenance of cell polarity	GO:0007163	167	0.018
histone modification	GO:0016570	106	0.018
nucleocytoplasmic transport	GO:0006913	72	0.017
organonitrogen compound metabolic process	GO:1901564	318	0.017
oxoacid metabolic process	GO:0043436	103	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
regulation of cell proliferation	GO:0042127	163	0.016
single organism nuclear import	GO:1902593	51	0.016
response to abiotic stimulus	GO:0009628	341	0.016
negative regulation of signaling	GO:0023057	219	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.015
protein modification process	GO:0036211	438	0.015
regulation of cell development	GO:0060284	215	0.015
rna localization	GO:0006403	115	0.015
carboxylic acid metabolic process	GO:0019752	92	0.015
striated muscle myosin thick filament assembly	GO:0071688	3	0.015
establishment of rna localization	GO:0051236	47	0.015
cellular protein localization	GO:0034613	160	0.014
negative regulation of cell communication	GO:0010648	223	0.014
organic acid metabolic process	GO:0006082	103	0.014
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.014
ribonucleotide catabolic process	GO:0009261	109	0.014
nucleobase containing small molecule metabolic process	GO:0055086	174	0.014
negative regulation of small gtpase mediated signal transduction	GO:0051058	13	0.014
regulation of nervous system development	GO:0051960	248	0.014
nitrogen compound transport	GO:0071705	85	0.014
regulation of cell differentiation	GO:0045595	302	0.014
male gamete generation	GO:0048232	201	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.014
chromatin remodeling	GO:0006338	72	0.014
positive regulation of transport	GO:0051050	92	0.014
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.013
spindle assembly involved in mitosis	GO:0090307	50	0.013
mrna metabolic process	GO:0016071	124	0.013
sister chromatid segregation	GO:0000819	92	0.013
endocytosis	GO:0006897	310	0.013
heterocycle catabolic process	GO:0046700	166	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.013
regulation of cell cycle process	GO:0010564	181	0.013
epithelial cell development	GO:0002064	274	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
protein acylation	GO:0043543	42	0.013
actin filament based process	GO:0030029	220	0.013
intracellular protein transport	GO:0006886	104	0.013
positive regulation of biosynthetic process	GO:0009891	316	0.013
regulation of catalytic activity	GO:0050790	185	0.013
mitotic spindle organization	GO:0007052	220	0.012
protein complex assembly	GO:0006461	200	0.012
rna processing	GO:0006396	147	0.012
rna transport	GO:0050658	46	0.012
regulation of multicellular organismal development	GO:2000026	414	0.012
regulation of neurogenesis	GO:0050767	158	0.012
aromatic compound catabolic process	GO:0019439	166	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
intracellular transport	GO:0046907	228	0.011
spermatogenesis	GO:0007283	200	0.011
appendage morphogenesis	GO:0035107	397	0.011
chromosome condensation	GO:0030261	41	0.011
small gtpase mediated signal transduction	GO:0007264	88	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
protein targeting to nucleus	GO:0044744	51	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.010
tube development	GO:0035295	244	0.010
positive regulation of cellular biosynthetic process	GO:0031328	316	0.010
regulation of cellular protein metabolic process	GO:0032268	243	0.010
response to radiation	GO:0009314	155	0.010
positive regulation of transcription dna templated	GO:0045893	266	0.010
organic substance catabolic process	GO:1901575	308	0.010
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.010
negative regulation of developmental process	GO:0051093	201	0.010
imaginal disc derived wing morphogenesis	GO:0007476	337	0.010

Nup54 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.030
	nervous system disease	DOID:863	0	0.018

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