| multicellular organismal aging | GO:0010259 | 140 | 0.229 | Fly |
| determination of adult lifespan | GO:0008340 | 137 | 0.129 | Fly |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.126 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.065 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.064 | |
| aging | GO:0007568 | 143 | 0.060 | Fly |
| regulation of cell development | GO:0060284 | 215 | 0.058 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.053 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.047 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.043 | |
| regulation of immune response | GO:0050776 | 118 | 0.041 | |
| endocytosis | GO:0006897 | 310 | 0.041 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.039 | |
| regulation of peptide hormone processing | GO:0060568 | 1 | 0.039 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.038 | |
| immune system process | GO:0002376 | 347 | 0.036 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.036 | |
| regulation of response to external stimulus | GO:0032101 | 115 | 0.035 | |
| regulation of defense response | GO:0031347 | 102 | 0.033 | |
| negative regulation of peptide hormone processing | GO:0060570 | 1 | 0.033 | |
| regulation of molecular function | GO:0065009 | 217 | 0.031 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.031 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.031 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.031 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.030 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.030 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.030 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.030 | |
| cellular response to light intensity | GO:0071484 | 1 | 0.029 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.029 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.029 | |
| activation of innate immune response | GO:0002218 | 4 | 0.028 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.028 | |
| cellular response to high light intensity | GO:0071486 | 1 | 0.028 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.028 | |
| response to other organism | GO:0051707 | 293 | 0.028 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.027 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.026 | |
| intracellular transport | GO:0046907 | 228 | 0.025 | |
| protein maturation | GO:0051604 | 71 | 0.025 | |
| cellular amide metabolic process | GO:0043603 | 80 | 0.025 | |
| appendage development | GO:0048736 | 401 | 0.025 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.025 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.024 | |
| protein localization | GO:0008104 | 284 | 0.024 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.024 | |
| regulation of neurogenesis | GO:0050767 | 158 | 0.023 | |
| response to high light intensity | GO:0009644 | 1 | 0.023 | |
| positive regulation of cell development | GO:0010720 | 61 | 0.023 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.023 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.022 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.022 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.022 | |
| regulation of immune system process | GO:0002682 | 176 | 0.022 | |
| protein modification process | GO:0036211 | 438 | 0.021 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.021 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.021 | |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.021 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.020 | |
| compound eye development | GO:0048749 | 307 | 0.020 | |
| regulation of neuron differentiation | GO:0045664 | 103 | 0.020 | |
| epithelial cell differentiation | GO:0030855 | 322 | 0.020 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.019 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.019 | |
| humoral immune response | GO:0006959 | 117 | 0.019 | |
| epithelial cell development | GO:0002064 | 274 | 0.019 | |
| cellular response to radiation | GO:0071478 | 52 | 0.019 | |
| regulation of response to biotic stimulus | GO:0002831 | 63 | 0.019 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.019 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.019 | |
| regulation of nervous system development | GO:0051960 | 248 | 0.019 | |
| body morphogenesis | GO:0010171 | 2 | 0.019 | |
| innate immune response | GO:0045087 | 144 | 0.019 | |
| columnar cuboidal epithelial cell development | GO:0002066 | 249 | 0.018 | |
| developmental growth | GO:0048589 | 280 | 0.018 | |
| regulation of localization | GO:0032879 | 275 | 0.018 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 2 | 0.018 | |
| regulation of response to stress | GO:0080134 | 200 | 0.018 | |
| developmental maturation | GO:0021700 | 172 | 0.018 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.018 | |
| dendrite development | GO:0016358 | 204 | 0.018 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.018 | |
| antimicrobial humoral response | GO:0019730 | 99 | 0.017 | |
| growth | GO:0040007 | 359 | 0.017 | |
| forebrain development | GO:0030900 | 2 | 0.017 | |
| water homeostasis | GO:0030104 | 3 | 0.017 | |
| immune response | GO:0006955 | 246 | 0.017 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.017 | |
| morphogenesis of an epithelium | GO:0002009 | 276 | 0.017 | |
| cell cell junction organization | GO:0045216 | 55 | 0.017 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.017 | |
| kidney development | GO:0001822 | 3 | 0.016 | |
| camera type eye development | GO:0043010 | 4 | 0.016 | |
| single organism cellular localization | GO:1902580 | 180 | 0.016 | |
| regulation of humoral immune response | GO:0002920 | 51 | 0.016 | |
| negative regulation of protein processing | GO:0010955 | 31 | 0.016 | |
| proteolysis | GO:0006508 | 192 | 0.016 | |
| cell cell junction assembly | GO:0007043 | 38 | 0.016 | |
| small gtpase mediated signal transduction | GO:0007264 | 88 | 0.015 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.015 | |
| negative regulation of response to external stimulus | GO:0032102 | 22 | 0.015 | |
| response to temperature stimulus | GO:0009266 | 106 | 0.015 | |
| regionalization | GO:0003002 | 416 | 0.015 | |
| regulation of hydrolase activity | GO:0051336 | 97 | 0.015 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.015 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.015 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.015 | |
| tube development | GO:0035295 | 244 | 0.015 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.015 | |
| response to light stimulus | GO:0009416 | 124 | 0.015 | |
| ras protein signal transduction | GO:0007265 | 88 | 0.015 | |
| eye development | GO:0001654 | 323 | 0.015 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.015 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 116 | 0.014 | |
| positive regulation of cell differentiation | GO:0045597 | 64 | 0.014 | |
| production of molecular mediator of immune response | GO:0002440 | 46 | 0.014 | |
| chemotaxis | GO:0006935 | 249 | 0.014 | |
| cell junction organization | GO:0034330 | 57 | 0.014 | |
| defense response to other organism | GO:0098542 | 225 | 0.014 | |
| ion transmembrane transport | GO:0034220 | 122 | 0.014 | |
| respiratory system development | GO:0060541 | 213 | 0.014 | |
| cell death | GO:0008219 | 279 | 0.014 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.014 | |
| phagocytosis | GO:0006909 | 215 | 0.014 | |
| response to wounding | GO:0009611 | 94 | 0.014 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.014 | |
| eye morphogenesis | GO:0048592 | 260 | 0.014 | |
| regulation of cellular localization | GO:0060341 | 136 | 0.013 | |
| imaginal disc pattern formation | GO:0007447 | 91 | 0.013 | |
| synapse assembly | GO:0007416 | 143 | 0.013 | |
| programmed cell death | GO:0012501 | 257 | 0.013 | |
| taxis | GO:0042330 | 304 | 0.013 | |
| centrosome organization | GO:0051297 | 163 | 0.013 | |
| digestive tract development | GO:0048565 | 149 | 0.013 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.013 | |
| positive regulation of nervous system development | GO:0051962 | 69 | 0.013 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.013 | |
| gland morphogenesis | GO:0022612 | 145 | 0.013 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.013 | |
| connective tissue development | GO:0061448 | 3 | 0.013 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.013 | |
| immune response regulating signaling pathway | GO:0002764 | 2 | 0.013 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.013 | |
| negative regulation of defense response | GO:0031348 | 35 | 0.013 | |
| immune response activating signal transduction | GO:0002757 | 2 | 0.012 | |
| multi multicellular organism process | GO:0044706 | 123 | 0.012 | |
| establishment of protein localization | GO:0045184 | 163 | 0.012 | |
| oocyte differentiation | GO:0009994 | 145 | 0.012 | |
| axon development | GO:0061564 | 297 | 0.012 | |
| regulation of antimicrobial humoral response | GO:0002759 | 50 | 0.012 | |
| catabolic process | GO:0009056 | 409 | 0.012 | |
| telencephalon development | GO:0021537 | 2 | 0.012 | |
| peptide metabolic process | GO:0006518 | 80 | 0.012 | |
| hindbrain development | GO:0030902 | 2 | 0.012 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.012 | |
| compound eye morphogenesis | GO:0001745 | 249 | 0.012 | |
| organelle assembly | GO:0070925 | 198 | 0.012 | |
| protein phosphorylation | GO:0006468 | 169 | 0.012 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 108 | 0.012 | |
| cell adhesion | GO:0007155 | 136 | 0.012 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 116 | 0.012 | |
| negative regulation of endopeptidase activity | GO:0010951 | 11 | 0.012 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.012 | |
| response to radiation | GO:0009314 | 155 | 0.012 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.012 | |
| spindle organization | GO:0007051 | 253 | 0.012 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.012 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.011 | |
| segmentation | GO:0035282 | 207 | 0.011 | |
| protein transport | GO:0015031 | 155 | 0.011 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.011 | |
| dna metabolic process | GO:0006259 | 227 | 0.011 | |
| carbohydrate derivative catabolic process | GO:1901136 | 118 | 0.011 | |
| wound healing spreading of epidermal cells | GO:0035313 | 1 | 0.011 | |
| negative regulation of proteolysis | GO:0045861 | 31 | 0.011 | |
| epiboly involved in wound healing | GO:0090505 | 2 | 0.011 | |
| defense response to bacterium | GO:0042742 | 178 | 0.011 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 136 | 0.011 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.011 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.011 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.011 | |
| positive regulation of neurogenesis | GO:0050769 | 41 | 0.011 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 2 | 0.011 | |
| protein import into nucleus | GO:0006606 | 51 | 0.011 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 93 | 0.011 | |
| protein processing | GO:0016485 | 68 | 0.011 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.011 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.011 | |
| regulation of toll signaling pathway | GO:0008592 | 17 | 0.010 | |
| regulation of transport | GO:0051049 | 181 | 0.010 | |
| camera type eye morphogenesis | GO:0048593 | 2 | 0.010 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.010 | |
| regulation of lipid transport | GO:0032368 | 3 | 0.010 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 81 | 0.010 | |
| nucleotide metabolic process | GO:0009117 | 161 | 0.010 | |
| response to monosaccharide | GO:0034284 | 4 | 0.010 | |
| epithelium migration | GO:0090132 | 148 | 0.010 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.010 | |
| salivary gland cell autophagic cell death | GO:0035071 | 83 | 0.010 | |
| regulation of cellular component size | GO:0032535 | 98 | 0.010 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.010 | |
| regulation of cell death | GO:0010941 | 173 | 0.010 | |