Drosophila melanogaster

24 known processes

wapl (Dmel_CG3707)

wings apart-like

(Aliases: l(1)N2,Dmel\CG3707,EG:87B1.2,wap,l(1)N5[72],pasc,l74,l(1)2Df,RNA D,C204,l(1)C204,N2,RNAD,CG3707,l(1)2Dd)

wapl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nucleobase containing compound metabolic processGO:00459342610.933
Human
meiotic chromosome segregationGO:0045132590.911
negative regulation of nucleic acid templated transcriptionGO:19035072400.911
meiotic cell cycleGO:00513211710.883
nuclear divisionGO:00002803320.845
negative regulation of cellular metabolic processGO:00313243820.833
Human
negative regulation of macromolecule biosynthetic processGO:00105582700.833
Human
negative regulation of gene expression epigeneticGO:0045814770.826
gene silencingGO:00164581380.824
meiotic nuclear divisionGO:00071261510.803
regulation of chromatin silencingGO:0031935360.787
negative regulation of rna biosynthetic processGO:19026792400.779
response to other organismGO:00517072930.758
regulation of chromosome organizationGO:0033044640.690
Human
negative regulation of gene expressionGO:00106293870.665
tube developmentGO:00352952440.664
meiotic cell cycle processGO:19030461320.658
regulation of cell cycleGO:00517262910.637
Human
spindle organizationGO:00070512530.624
chromosome organizationGO:00512763600.615
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.602
Human
dendrite morphogenesisGO:00488131990.573
negative regulation of rna metabolic processGO:00512532510.555
positive regulation of transcription dna templatedGO:00458932660.551
covalent chromatin modificationGO:00165691060.499
positive regulation of nucleobase containing compound metabolic processGO:00459353320.490
chromatin modificationGO:00165681470.452
regulation of transcription from rna polymerase ii promoterGO:00063573780.449
reproductive structure developmentGO:0048608740.447
central nervous system developmentGO:00074172010.436
regulation of organelle organizationGO:00330431960.425
Human
positive regulation of cellular component organizationGO:00511301560.414
histone acetylationGO:0016573380.408
histone modificationGO:00165701060.394
morphogenesis of an epitheliumGO:00020092760.384
regulation of cellular protein metabolic processGO:00322682430.378
embryo development ending in birth or egg hatchingGO:00097921520.364
Worm
muscle structure developmentGO:00610612240.361
tissue morphogenesisGO:00487292970.348
establishment of localization in cellGO:00516494020.333
cellular response to dna damage stimulusGO:00069742230.321
negative regulation of mitotic cell cycle phase transitionGO:19019911030.314
organelle assemblyGO:00709251980.312
positive regulation of nitrogen compound metabolic processGO:00511733540.311
matingGO:00076181200.309
mitotic cell cycle checkpointGO:0007093880.297
purine nucleotide catabolic processGO:00061951090.294
regulation of protein metabolic processGO:00512462560.293
dna metabolic processGO:00062592270.278
Human
multi organism behaviorGO:00517051750.270
Worm
ribonucleotide metabolic processGO:00092591450.267
multicellular organismal reproductive behaviorGO:00330571100.265
Worm
mitotic dna damage checkpointGO:0044773740.265
peptidyl lysine modificationGO:0018205570.259
imaginal disc derived appendage developmentGO:00487373990.258
positive regulation of cellular biosynthetic processGO:00313283160.252
dendrite developmentGO:00163582040.244
negative regulation of nitrogen compound metabolic processGO:00511722650.241
Human
protein modification by small protein conjugation or removalGO:00706471060.239
chromatin silencingGO:0006342760.230
sensory organ morphogenesisGO:00905962600.228
positive regulation of nucleic acid templated transcriptionGO:19035082660.219
organelle fissionGO:00482853400.219
embryonic morphogenesisGO:00485982060.218
protein acetylationGO:0006473390.209
response to external biotic stimulusGO:00432072930.201
epithelial cell differentiationGO:00308553220.201
cell migrationGO:00164772380.198
positive regulation of rna biosynthetic processGO:19026802660.196
sex differentiationGO:0007548810.191
negative regulation of cellular component organizationGO:00511291080.190
Human
chromatin organizationGO:00063252070.187
positive regulation of organelle organizationGO:0010638650.183
compound eye photoreceptor cell differentiationGO:00017511400.183
cellular protein modification processGO:00064644380.182
dna damage checkpointGO:0000077780.182
regulation of gene expression epigeneticGO:00400291280.178
internal protein amino acid acetylationGO:0006475380.178
nucleoside triphosphate metabolic processGO:00091411200.172
regulation of molecular functionGO:00650092170.168
Human
purine ribonucleotide catabolic processGO:00091541090.167
protein complex assemblyGO:00064612000.165
negative regulation of cellular biosynthetic processGO:00313272770.164
Human
regulation of catalytic activityGO:00507901850.156
response to biotic stimulusGO:00096072940.152
nucleotide catabolic processGO:00091661090.149
regulation of cell cycle phase transitionGO:19019871300.149
epithelial cell developmentGO:00020642740.147
chromosome segregationGO:00070591570.147
purine nucleotide metabolic processGO:00061631460.143
columnar cuboidal epithelial cell developmentGO:00020662490.142
organonitrogen compound metabolic processGO:19015643180.142
regulation of immune system processGO:00026821760.138
peptidyl lysine acetylationGO:0018394390.137
localization of cellGO:00516742570.135
establishment or maintenance of cell polarityGO:00071631670.132
positive regulation of macromolecule biosynthetic processGO:00105572830.132
macromolecular complex assemblyGO:00650032560.132
positive regulation of gene expressionGO:00106282900.131
immune system processGO:00023763470.130
neuron projection guidanceGO:00974852410.129
internal peptidyl lysine acetylationGO:0018393380.128
transcription from rna polymerase ii promoterGO:00063663680.124
cell divisionGO:00513012480.121
compound eye photoreceptor developmentGO:0042051780.117
ribonucleoside triphosphate catabolic processGO:00092031080.117
negative regulation of cell cycle processGO:00109481090.117
Human
dna integrity checkpointGO:0031570810.117
negative regulation of response to stimulusGO:00485852580.115
heterocycle catabolic processGO:00467001660.114
immune responseGO:00069552460.112
regulation of anatomical structure morphogenesisGO:00226032420.111
establishment of protein localizationGO:00451841630.111
protein transportGO:00150311550.109
regulation of gene silencingGO:0060968630.109
negative regulation of transcription dna templatedGO:00458922370.108
cellular catabolic processGO:00442483720.107
purine ribonucleoside monophosphate metabolic processGO:0009167500.103
mitotic spindle organizationGO:00070522200.102
leg disc developmentGO:0035218920.102
nucleotide metabolic processGO:00091171610.102
negative regulation of biosynthetic processGO:00098902770.101
Human
eye photoreceptor cell developmentGO:0042462810.100
purine ribonucleoside metabolic processGO:00461281270.098
ribonucleoside triphosphate metabolic processGO:00091991190.098
female meiosis chromosome segregationGO:0016321330.098
negative regulation of cell cycle phase transitionGO:19019881030.096
blastoderm segmentationGO:00073501590.095
defense responseGO:00069523000.094
regulation of protein modification processGO:00313991120.092
cell motilityGO:00488702510.091
imaginal disc derived wing morphogenesisGO:00074763370.090
regulation of cellular amino acid metabolic processGO:000652100.089
columnar cuboidal epithelial cell differentiationGO:00020652560.087
protein modification processGO:00362114380.086
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.085
single organism catabolic processGO:00447122280.084
regulation of phosphorus metabolic processGO:00511742100.083
purine containing compound metabolic processGO:00725211550.081
regulation of immune responseGO:00507761180.081
positive regulation of biosynthetic processGO:00098913160.078
defense response to other organismGO:00985422250.078
multi multicellular organism processGO:00447061230.078
Worm
imaginal disc derived appendage morphogenesisGO:00351143950.077
purine nucleoside metabolic processGO:00422781270.077
carbohydrate derivative metabolic processGO:19011352170.077
establishment of planar polarityGO:0001736870.077
regulation of hydrolase activityGO:0051336970.076
cell fate specificationGO:0001708710.073
protein maturationGO:0051604710.072
positive regulation of hydrolase activityGO:0051345780.069
regulation of cellular ketone metabolic processGO:001056530.068
regulation of cellular amine metabolic processGO:003323830.068
male mating behaviorGO:0060179700.067
cell cycle checkpointGO:0000075950.067
purine ribonucleotide metabolic processGO:00091501450.067
axon developmentGO:00615642970.067
single organism cellular localizationGO:19025801800.064
Human
regulation of chromatin modificationGO:1903308280.064
dna repairGO:0006281540.063
anterior posterior pattern specificationGO:00099521360.062
embryonic pattern specificationGO:00098801740.062
positive regulation of chromatin silencingGO:0031937160.061
chorion containing eggshell formationGO:00073041050.060
organophosphate metabolic processGO:00196371950.059
regulation of cell proliferationGO:00421271630.059
eye morphogenesisGO:00485922600.058
female meiotic divisionGO:0007143700.058
larval developmentGO:00021641040.058
positive regulation of macromolecule metabolic processGO:00106044050.057
regulation of cell shapeGO:00083601130.057
head developmentGO:00603221350.057
intracellular transportGO:00469072280.057
purine ribonucleoside triphosphate catabolic processGO:00092071080.056
small molecule metabolic processGO:00442813050.055
purine nucleoside triphosphate metabolic processGO:00091441190.054
brain developmentGO:00074201200.053
response to alcoholGO:0097305950.053
eye photoreceptor cell differentiationGO:00017541450.052
positive regulation of molecular functionGO:00440931360.052
histone h3 k9 acetylationGO:004397030.052
macromolecule catabolic processGO:00090571610.051
amine metabolic processGO:0009308120.051
aromatic compound catabolic processGO:00194391660.050
neurological system processGO:00508773580.050
protein localizationGO:00081042840.050
Human
body morphogenesisGO:001017120.050
compound eye morphogenesisGO:00017452490.050
digestive system developmentGO:00551231490.049
chromatin remodelingGO:0006338720.049
cuticle developmentGO:0042335860.048
defense response to bacteriumGO:00427421780.048
cellular ketone metabolic processGO:0042180240.048
regulation of proteolysisGO:0030162870.048
deathGO:00162652840.048
negative regulation of signal transductionGO:00099682060.048
regulation of organ morphogenesisGO:2000027780.048
positive regulation of mitotic cell cycleGO:0045931340.047
regulation of cell deathGO:00109411730.047
protein modification by small protein removalGO:0070646280.047
purine nucleoside catabolic processGO:00061521120.047
ribonucleoside metabolic processGO:00091191270.046
morphogenesis of a polarized epitheliumGO:0001738930.046
cellular macromolecule localizationGO:00707272200.045
Human
mitotic g2 dna damage checkpointGO:0007095690.045
glycosyl compound catabolic processGO:19016581120.044
protein deacetylationGO:000647690.044
photoreceptor cell differentiationGO:00465301700.043
negative regulation of organelle organizationGO:0010639560.043
Human
actin cytoskeleton organizationGO:00300362060.043
eye developmentGO:00016543230.043
meiosis iGO:0007127590.043
protein complex biogenesisGO:00702712010.042
positive regulation of catalytic activityGO:00430851180.042
cell cycle phase transitionGO:00447701400.042
appendage developmentGO:00487364010.042
purine ribonucleoside triphosphate metabolic processGO:00092051190.042
negative regulation of cellular protein metabolic processGO:0032269850.041
development of primary sexual characteristicsGO:0045137500.041
nucleoside catabolic processGO:00091641120.041
protein acylationGO:0043543420.041
regionalizationGO:00030024160.041
regulation of meiosisGO:004002030.040
chromatin mediated maintenance of transcriptionGO:004809670.040
regulation of small gtpase mediated signal transductionGO:0051056930.040
reproductive system developmentGO:0061458740.040
negative regulation of cell communicationGO:00106482230.039
purine nucleoside triphosphate catabolic processGO:00091461080.039
dna methylationGO:000630640.039
positive regulation of nucleotide metabolic processGO:0045981550.039
embryonic development via the syncytial blastodermGO:00017001480.038
ras protein signal transductionGO:0007265880.037
vesicle mediated transportGO:00161923810.037
organic substance transportGO:00717022570.037
glycosyl compound metabolic processGO:19016571270.037
nucleoside metabolic processGO:00091161270.037
nucleoside phosphate metabolic processGO:00067531620.037
positive regulation of cellular protein metabolic processGO:00322701180.036
axon guidanceGO:00074112330.036
neuron recognitionGO:00080381010.036
positive regulation of transferase activityGO:0051347260.036
single organism intracellular transportGO:19025822070.035
regulation of mitotic cell cycle phase transitionGO:19019901300.035
gonad developmentGO:0008406500.035
negative regulation of cell cycleGO:00457861160.035
Human
cellular protein localizationGO:00346131600.034
Human
compound eye developmentGO:00487493070.034
gtp metabolic processGO:0046039720.034
antimicrobial humoral responseGO:0019730990.034
response to ecdysoneGO:0035075340.033
purine ribonucleoside catabolic processGO:00461301120.033
small gtpase mediated signal transductionGO:0007264880.033
positive regulation of response to stimulusGO:00485843230.033
regulation of phosphate metabolic processGO:00192202100.033
meiotic chromosome condensationGO:001003230.033
regulation of cell developmentGO:00602842150.032
limb developmentGO:006017310.032
endocytosisGO:00068973100.032
protein dna complex subunit organizationGO:0071824860.032
developmental programmed cell deathGO:00106231380.031
intracellular receptor signaling pathwayGO:0030522190.031
nuclear transportGO:0051169720.031
regulation of chromatin organizationGO:1902275320.031
appendage morphogenesisGO:00351073970.031
growthGO:00400073590.031
leg disc morphogenesisGO:0007478800.030
nucleoside triphosphate catabolic processGO:00091431080.029
negative regulation of signalingGO:00230572190.029
renal system developmentGO:0072001720.028
embryonic organ developmentGO:0048568500.028
organic substance catabolic processGO:19015753080.028
positive regulation of protein metabolic processGO:00512471280.027
ribose phosphate metabolic processGO:00196931450.027
positive regulation of protein modification processGO:0031401580.027
cellular amino acid metabolic processGO:0006520610.027
cellular nitrogen compound catabolic processGO:00442701650.027
regulation of ras protein signal transductionGO:0046578930.026
intracellular signal transductionGO:00355563000.026
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.026
single organism membrane organizationGO:0044802930.025
dna conformation changeGO:00711031050.025
g2 dna damage checkpointGO:0031572690.024
mitotic cell cycle phase transitionGO:00447721380.024
nucleobase containing compound catabolic processGO:00346551650.024
organophosphate catabolic processGO:00464341120.024
mitotic dna integrity checkpointGO:0044774750.024
positive regulation of phosphate metabolic processGO:00459371390.024
cytoskeleton dependent cytokinesisGO:0061640810.023
regulation of response to gamma radiationGO:200122840.023
response to organic substanceGO:00100332840.023
axis specificationGO:00097981670.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
regulation of intracellular protein transportGO:0033157460.023
regulation of cellular catabolic processGO:00313291570.023
regulation of transferase activityGO:0051338580.022
negative regulation of chromosome organizationGO:2001251190.022
Human
reproductive behaviorGO:00190981220.022
Worm
protein targetingGO:0006605640.022
purine containing compound catabolic processGO:00725231120.022
establishment of protein localization to organelleGO:0072594620.022
regulation of apoptotic processGO:00429811300.022
mitotic cell cycle embryonicGO:0045448380.022
nucleocytoplasmic transportGO:0006913720.021
positive regulation of proteolysisGO:0045862520.021
dna methylation or demethylationGO:004472840.021
regulation of compound eye cone cell fate specificationGO:004268240.021
cellular macromolecular complex assemblyGO:00346221530.021
regulation of hemocyte proliferationGO:0035206370.021
negative regulation of neurogenesisGO:0050768530.021
positive regulation of cellular component biogenesisGO:0044089800.020
regulation of microtubule based processGO:0032886490.020
hematopoietic or lymphoid organ developmentGO:0048534570.020
regulation of protein transportGO:0051223570.020
regulation of cell differentiationGO:00455953020.020
negative regulation of catalytic activityGO:0043086420.020
regulation of protein phosphorylationGO:0001932640.020
regulation of cellular component biogenesisGO:00440872010.020
nucleoside phosphate catabolic processGO:19012921100.020
regulation of cell fate specificationGO:0042659270.020
regulation of transportGO:00510491810.019
r3 r4 cell differentiationGO:0048056120.019
ribonucleotide catabolic processGO:00092611090.019
dna alkylationGO:000630540.019
hemopoiesisGO:0030097460.019
axon choice point recognitionGO:0016198260.019
homeostatic processGO:00425921990.019
regulation of cell fate commitmentGO:0010453290.019
cellular macromolecule catabolic processGO:00442651360.019
regulation of purine nucleotide metabolic processGO:1900542620.019
digestive tract developmentGO:00485651490.018
regulation of neurogenesisGO:00507671580.018
ribonucleoside monophosphate metabolic processGO:0009161510.018
regulation of protein import into nucleusGO:0042306280.018
regulation of neuron differentiationGO:00456641030.018
response to sterolGO:0036314340.018
regulation of mitotic cell cycleGO:00073461900.018
post embryonic appendage morphogenesisGO:00351203850.017
jnk cascadeGO:0007254500.017
regulation of programmed cell deathGO:00430671520.017
response to ketoneGO:1901654340.017
protein processingGO:0016485680.017
regulation of purine nucleotide catabolic processGO:0033121480.017
tube morphogenesisGO:00352391910.017
cellular component assembly involved in morphogenesisGO:00109271510.017
mitotic g2 m transition checkpointGO:0044818700.017
negative regulation of multicellular organismal processGO:00512411420.017
nucleosome mobilizationGO:004276690.016
striated muscle cell developmentGO:0055002500.016
regulation of embryonic developmentGO:0045995680.016
cell proliferationGO:00082832990.016
digestive tract morphogenesisGO:00485461270.016
intracellular protein transportGO:00068861040.016
regulation of response to stressGO:00801342000.016
regulation of histone modificationGO:0031056200.016
cellular response to organic substanceGO:00713101320.016
regulation of multicellular organismal developmentGO:20000264140.016
histone h3 k27 methylationGO:007073460.016
cellular response to endogenous stimulusGO:0071495800.016
regulation of cellular response to stressGO:0080135890.016
multi organism reproductive behaviorGO:00447051210.016
Worm
tissue migrationGO:00901301550.016
negative regulation of proteolysisGO:0045861310.015
positive regulation of catabolic processGO:00098961050.015
sister chromatid segregationGO:0000819920.015
protein modification by small protein conjugationGO:0032446790.015
negative regulation of phosphate metabolic processGO:0045936450.015
actin filament based processGO:00300292200.015
atp metabolic processGO:0046034490.015
actomyosin structure organizationGO:0031032560.015
humoral immune responseGO:00069591170.015
organonitrogen compound catabolic processGO:19015651280.015
regulation of protein targetingGO:1903533290.015
regulation of ras gtpase activityGO:0032318380.014
compound eye retinal cell programmed cell deathGO:0046667230.014
negative regulation of protein metabolic processGO:0051248850.014
photoreceptor cell developmentGO:0042461960.014
cellular protein complex assemblyGO:0043623710.014
epithelial tube morphogenesisGO:0060562880.014
compound eye photoreceptor fate commitmentGO:0001752360.014
regulation of phosphatase activityGO:001092130.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.014
segmentationGO:00352822070.014
purine nucleoside monophosphate metabolic processGO:0009126500.014
pupal developmentGO:0035209110.013
dna packagingGO:0006323910.013
catabolic processGO:00090564090.013
regulation of embryonic cell shapeGO:0016476300.013
regulation of localizationGO:00328792750.013
Human
regulation of intracellular transportGO:0032386640.013
histone h4 k16 acetylationGO:004398440.013
camera type eye developmentGO:004301040.013
regulation of nucleocytoplasmic transportGO:0046822350.013
locomotory behaviorGO:00076261760.013
proteolysisGO:00065081920.012
nucleobase containing small molecule metabolic processGO:00550861740.012
regulation of retinal cell programmed cell deathGO:0046668180.012
dna templated transcriptional preinitiation complex assemblyGO:0070897200.012
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encodedGO:000807020.012
guanosine containing compound metabolic processGO:1901068740.012
positive regulation of immune system processGO:0002684680.012
compound eye cone cell fate commitmentGO:004267650.012
wing disc morphogenesisGO:00074723440.012
spindle checkpointGO:0031577110.012
axon midline choice point recognitionGO:0016199260.012
macromolecule deacylationGO:0098732110.012
eye photoreceptor cell fate commitmentGO:0042706370.012
male gamete generationGO:00482322010.012
taxisGO:00423303040.012
dorsal vessel heart proper cell fate commitmentGO:003505320.012
axonogenesisGO:00074092900.012
ovarian follicle cell developmentGO:00307072480.012
ribonucleoside monophosphate catabolic processGO:0009158390.012
epidermis developmentGO:0008544650.012
histone deacetylationGO:001657590.012
organic cyclic compound catabolic processGO:19013611680.012
negative regulation of protein processingGO:0010955310.012
chemical homeostasisGO:0048878920.012
positive regulation of nucleoside metabolic processGO:0045979470.011
embryonic hemopoiesisGO:0035162260.011
regulation of protein localizationGO:0032880760.011
Human
chromosome organization involved in meiosisGO:0070192100.011
negative regulation of chromatin silencingGO:003193690.011
negative regulation of protein modification processGO:0031400290.011
retina development in camera type eyeGO:006004140.011
negative regulation of phosphorylationGO:0042326350.011
response to organic cyclic compoundGO:0014070890.011
ovipositionGO:0018991190.011
Worm
mitochondrial membrane organizationGO:000700630.011
wnt signaling pathwayGO:0016055980.011
genitalia developmentGO:0048806260.011
cytoplasmic transportGO:00164821300.011
regulation of striated muscle contractionGO:000694220.010
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.010
regulation of proteasomal protein catabolic processGO:0061136390.010
negative regulation of histone methylationGO:003106130.010
response to endogenous stimulusGO:00097191190.010
phagocytosisGO:00069092150.010
establishment of ommatidial planar polarityGO:0042067490.010
protein phosphorylationGO:00064681690.010
regulation of nucleoside metabolic processGO:0009118500.010
phosphorylationGO:00163102940.010
cellular amine metabolic processGO:0044106120.010
protein catabolic processGO:00301631010.010

wapl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.188
organ system cancerDOID:005068600.055
cancerDOID:16200.055