Drosophila melanogaster

84 known processes

tok (Dmel_CG6863)

tolkin

(Aliases: Tlr,tldr-1,CG6863,TOK,tlr,Tok,CT21251,tlr1,Dmel\CG6863,Tlr-1,tldr1,tlr-1)

tok biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
motor neuron axon guidanceGO:0008045580.992
chemotaxisGO:00069352490.972
taxisGO:00423303040.916
neuron projection guidanceGO:00974852410.864
cell recognitionGO:00080371020.828
axon guidanceGO:00074112330.792
bmp signaling pathwayGO:0030509270.765
Zebrafish
axon developmentGO:00615642970.754
regulation of bmp signaling pathwayGO:0030510230.748
Zebrafish
muscle structure developmentGO:00610612240.713
axonogenesisGO:00074092900.607
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.590
Zebrafish
regulation of multicellular organismal developmentGO:20000264140.564
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.546
Zebrafish
enzyme linked receptor protein signaling pathwayGO:00071671790.537
Zebrafish Fly
regulation of cell projection organizationGO:0031344920.511
transcription from rna polymerase ii promoterGO:00063663680.468
Fly
neuromuscular junction developmentGO:00075281490.465
photoreceptor cell axon guidanceGO:0072499230.408
cell divisionGO:00513012480.400
retinal ganglion cell axon guidanceGO:0031290120.395
regulation of developmental growthGO:00486381740.393
imaginal disc derived appendage morphogenesisGO:00351143950.387
regulation of neurogenesisGO:00507671580.380
synapse organizationGO:00508081960.377
growthGO:00400073590.369
olfactory bulb axon guidanceGO:007167830.359
regulation of nervous system developmentGO:00519602480.353
regulation of neuron differentiationGO:00456641030.351
regulation of neuron projection developmentGO:0010975690.347
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.318
Fly
dendrite developmentGO:00163582040.315
developmental growth involved in morphogenesisGO:0060560650.307
forebrain developmentGO:003090020.303
regulation of axonogenesisGO:0050770320.301
positive regulation of multicellular organismal processGO:00512401430.296
Human
sensory organ morphogenesisGO:00905962600.295
regulation of transcription from rna polymerase ii promoterGO:00063573780.282
Zebrafish Fly
appendage morphogenesisGO:00351073970.281
inositol lipid mediated signalingGO:004801740.260
response to growth factorGO:0070848310.258
semaphorin plexin signaling pathwayGO:007152640.243
regulation of photoreceptor cell axon guidanceGO:200028950.240
developmental growthGO:00485892800.223
regulation of cell differentiationGO:00455953020.216
neuron recognitionGO:00080381010.215
regulation of locomotionGO:0040012420.184
axon extensionGO:0048675320.165
regulation of anatomical structure sizeGO:00900661630.152
nucleobase containing small molecule metabolic processGO:00550861740.151
terminal region determinationGO:0007362250.149
Fly
imaginal disc derived appendage developmentGO:00487373990.146
regulation of behaviorGO:0050795750.145
establishment of localization in cellGO:00516494020.143
regulation of axon extension involved in axon guidanceGO:004884140.143
regulation of cell sizeGO:0008361630.136
negative regulation of developmental processGO:00510932010.132
regulation of cell morphogenesisGO:00226041630.126
central nervous system developmentGO:00074172010.125
purine nucleotide metabolic processGO:00061631460.123
cell maturationGO:00484691440.123
Fly
cellular protein modification processGO:00064644380.121
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010090.118
Zebrafish
secretion by cellGO:00329401010.116
leg disc developmentGO:0035218920.111
regulation of cellular component sizeGO:0032535980.109
carbohydrate derivative metabolic processGO:19011352170.108
cation transportGO:00068121100.108
regulation of anatomical structure morphogenesisGO:00226032420.106
positive regulation of growthGO:0045927750.103
cellular amine metabolic processGO:0044106120.103
small molecule metabolic processGO:00442813050.101
basement membrane organizationGO:0071711100.097
axon midline choice point recognitionGO:0016199260.096
positive regulation of developmental growthGO:0048639620.095
regulation of cell developmentGO:00602842150.094
regulation of molecular functionGO:00650092170.093
positive regulation of axonogenesisGO:005077220.093
negative regulation of signalingGO:00230572190.092
organonitrogen compound metabolic processGO:19015643180.092
tissue morphogenesisGO:00487292970.091
Zebrafish
carboxylic acid metabolic processGO:0019752920.087
localization of cellGO:00516742570.082
post embryonic appendage morphogenesisGO:00351203850.081
regulation of protein metabolic processGO:00512462560.081
locomotory behaviorGO:00076261760.081
tripartite regional subdivisionGO:00073511030.080
Fly
gliogenesisGO:0042063800.079
regulation of growthGO:00400082330.079
regulation of axon guidanceGO:1902667100.078
camera type eye developmentGO:004301040.078
catabolic processGO:00090564090.077
zygotic determination of anterior posterior axis embryoGO:0007354270.075
Fly
dendrite morphogenesisGO:00488131990.074
imaginal disc derived wing morphogenesisGO:00074763370.073
eye morphogenesisGO:00485922600.072
regulation of catalytic activityGO:00507901850.068
body morphogenesisGO:001017120.068
negative regulation of response to stimulusGO:00485852580.067
heterotypic cell cell adhesionGO:003411310.066
response to light stimulusGO:00094161240.065
kidney developmentGO:000182230.065
positive regulation of catalytic activityGO:00430851180.065
ion transportGO:00068111450.061
positive regulation of phagocytosis engulfmentGO:006010010.061
immune system developmentGO:0002520570.061
Zebrafish
purine containing compound metabolic processGO:00725211550.060
regulation of metal ion transportGO:0010959150.060
axonal defasciculationGO:0007414120.059
appendage developmentGO:00487364010.059
gland developmentGO:00487321910.059
immune system processGO:00023763470.059
Zebrafish
single organism catabolic processGO:00447122280.059
organic acid metabolic processGO:00060821030.058
secretionGO:00469031090.057
positive regulation of cellular amine metabolic processGO:003324000.057
purine ribonucleotide metabolic processGO:00091501450.057
connective tissue developmentGO:006144830.057
Human
negative regulation of signal transductionGO:00099682060.056
regulation of cellular amine metabolic processGO:003323830.056
phosphatidylinositol mediated signalingGO:004801540.056
organic cyclic compound catabolic processGO:19013611680.055
positive regulation of axon extensionGO:004577320.055
vesicle mediated transportGO:00161923810.055
carbohydrate derivative catabolic processGO:19011361180.055
protein modification processGO:00362114380.054
exocrine system developmentGO:00352721620.054
axon choice point recognitionGO:0016198260.054
mitotic cytokinesisGO:0000281500.054
negative regulation of multicellular organismal processGO:00512411420.053
positive regulation of signal transductionGO:00099672230.051
Zebrafish
tissue migrationGO:00901301550.051
carbohydrate derivative biosynthetic processGO:1901137850.050
detection of light stimulusGO:0009583580.050
endocytosisGO:00068973100.050
positive regulation of apoptotic cell clearanceGO:200042720.049
organ growthGO:0035265560.049
positive regulation of macromolecule metabolic processGO:00106044050.049
multi multicellular organism processGO:00447061230.049
wing disc morphogenesisGO:00074723440.049
positive regulation of nucleobase containing compound metabolic processGO:00459353320.048
regulation of cell morphogenesis involved in differentiationGO:0010769610.048
positive regulation of bmp signaling pathwayGO:003051350.048
Zebrafish
determination of dorsal ventral asymmetryGO:004826230.048
Zebrafish
positive regulation of cell migrationGO:003033520.047
glycoprotein biosynthetic processGO:0009101410.047
nucleotide metabolic processGO:00091171610.047
salivary gland morphogenesisGO:00074351450.047
positive regulation of cell motilityGO:200014730.047
homeostatic processGO:00425921990.045
single organism carbohydrate metabolic processGO:0044723720.045
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.045
positive regulation of cellular amino acid metabolic processGO:004576400.044
neuron projection extensionGO:1990138320.044
positive regulation of cellular biosynthetic processGO:00313283160.044
organophosphate catabolic processGO:00464341120.043
multicellular organismal reproductive behaviorGO:00330571100.043
leg disc morphogenesisGO:0007478800.043
positive regulation of response to stimulusGO:00485843230.043
Zebrafish
imaginal disc derived wing vein specificationGO:0007474480.043
positive regulation of cellular component organizationGO:00511301560.043
positive regulation of nitrogen compound metabolic processGO:00511733540.043
eye developmentGO:00016543230.042
response to external biotic stimulusGO:00432072930.042
programmed cell deathGO:00125012570.042
detection of stimulusGO:00516061560.042
cellular ketone metabolic processGO:0042180240.042
positive regulation of signalingGO:00230562430.041
Zebrafish
purine nucleoside catabolic processGO:00061521120.041
circulatory system developmentGO:0072359820.041
Zebrafish
cell migrationGO:00164772380.041
regulation of cell growthGO:0001558430.041
positive regulation of molecular functionGO:00440931360.040
positive regulation of cell communicationGO:00106472500.039
Zebrafish
negative regulation of nervous system developmentGO:0051961920.039
cell type specific apoptotic processGO:0097285380.039
regulation of secretion by cellGO:1903530390.039
spinal cord developmentGO:002151010.039
maintenance of cell polarityGO:0030011180.038
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.038
single organism behaviorGO:00447083910.037
head developmentGO:00603221350.037
developmental maturationGO:00217001720.037
Fly
regulation of intracellular signal transductionGO:19025312360.036
imaginal disc derived leg morphogenesisGO:0007480800.035
regulation of phosphorus metabolic processGO:00511742100.034
morphogenesis of an epitheliumGO:00020092760.034
nephron developmentGO:007200630.034
glial cell developmentGO:0021782270.034
neuron migrationGO:000176450.034
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.034
gland morphogenesisGO:00226121450.034
peripheral nervous system developmentGO:0007422520.033
glycoprotein metabolic processGO:0009100410.033
nucleobase containing compound catabolic processGO:00346551650.033
nucleoside catabolic processGO:00091641120.032
organic substance catabolic processGO:19015753080.032
positive regulation of cellular component biogenesisGO:0044089800.032
response to abiotic stimulusGO:00096283410.032
erbb signaling pathwayGO:0038127580.032
regulation of cellular component movementGO:0051270420.032
regulation of ion transportGO:0043269390.032
positive regulation of rna biosynthetic processGO:19026802660.031
detection of abiotic stimulusGO:0009582660.031
actin filament based processGO:00300292200.031
negative regulation of apoptotic processGO:0043066630.031
insulin receptor signaling pathwayGO:0008286250.031
response to organic substanceGO:00100332840.031
mesenchymal cell differentiationGO:004876210.030
positive regulation of biosynthetic processGO:00098913160.030
dendrite guidanceGO:0070983210.030
negative regulation of rho protein signal transductionGO:003502410.030
regulation of phosphate metabolic processGO:00192202100.030
neuromuscular synaptic transmissionGO:0007274670.030
digestive tract developmentGO:00485651490.030
Zebrafish
embryonic morphogenesisGO:00485982060.030
Zebrafish
ras protein signal transductionGO:0007265880.030
phosphatidylinositol 3 kinase signalingGO:001406540.029
compound eye morphogenesisGO:00017452490.029
synapse assemblyGO:00074161430.029
negative regulation of cell communicationGO:00106482230.029
purine nucleoside triphosphate metabolic processGO:00091441190.029
cellular amino acid metabolic processGO:0006520610.029
gtp catabolic processGO:0006184720.028
epithelial cell differentiationGO:00308553220.028
Zebrafish
positive regulation of cell growthGO:0030307190.027
cellular response to chemical stimulusGO:00708871990.027
positive regulation of transcription dna templatedGO:00458932660.027
nucleoside phosphate metabolic processGO:00067531620.027
immune response regulating signaling pathwayGO:000276420.027
axis specificationGO:00097981670.027
Fly
response to nitrogen compoundGO:1901698900.027
ribose phosphate metabolic processGO:00196931450.027
metal ion transportGO:0030001740.027
negative regulation of programmed cell deathGO:0043069720.027
regulation of protein modification processGO:00313991120.026
negative regulation of cell differentiationGO:00455961430.026
positive regulation of phosphate metabolic processGO:00459371390.026
regulation of cellular amino acid metabolic processGO:000652100.026
notch signaling pathwayGO:00072191200.026
tube developmentGO:00352952440.026
Zebrafish
glycosyl compound catabolic processGO:19016581120.026
cytokinesisGO:0000910900.026
adult behaviorGO:00305341370.025
carbohydrate metabolic processGO:0005975820.025
positive regulation of developmental processGO:00510941430.025
Human
salivary gland developmentGO:00074311620.025
synaptic growth at neuromuscular junctionGO:00511241190.025
anterior posterior axis specification embryoGO:00085951030.025
Fly
regulation of protein tyrosine kinase activityGO:006109790.025
ribonucleotide metabolic processGO:00092591450.024
ectodermal placode developmentGO:007169640.024
gonad developmentGO:0008406500.024
glandular epithelial cell differentiationGO:000206710.024
regionalizationGO:00030024160.023
Zebrafish Fly
limb morphogenesisGO:003510810.023
cellular nitrogen compound catabolic processGO:00442701650.023
protein localizationGO:00081042840.023
cell motilityGO:00488702510.023
anterior posterior axis specificationGO:00099481090.023
Fly
reproductive behaviorGO:00190981220.023
response to endogenous stimulusGO:00097191190.022
blastoderm segmentationGO:00073501590.022
Fly
amine metabolic processGO:0009308120.022
stem cell developmentGO:0048864790.022
regulation of meiosisGO:004002030.022
cellular protein complex disassemblyGO:0043624350.022
glial cell differentiationGO:0010001350.022
regulation of cell motilityGO:2000145230.022
phosphorylationGO:00163102940.022
heterocycle catabolic processGO:00467001660.022
multi organism behaviorGO:00517051750.022
regulation of cellular protein metabolic processGO:00322682430.021
purine ribonucleoside metabolic processGO:00461281270.021
cellular response to growth factor stimulusGO:0071363300.021
ribonucleoside metabolic processGO:00091191270.021
regulation of extent of cell growthGO:006138780.021
regulation of organelle organizationGO:00330431960.021
epidermal growth factor receptor signaling pathwayGO:0007173580.021
regulation of hydrolase activityGO:0051336970.021
regulation of epithelial cell migrationGO:0010632120.020
positive regulation of establishment of protein localization to plasma membraneGO:009000430.020
positive regulation of nervous system developmentGO:0051962690.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
detection of external stimulusGO:0009581660.020
neuron projection extension involved in neuron projection guidanceGO:1902284100.020
compound eye developmentGO:00487493070.020
wnt signaling pathwayGO:0016055980.020
epithelial cell migration open tracheal systemGO:0007427320.020
embryonic organ developmentGO:0048568500.020
Zebrafish
mesoderm morphogenesisGO:0048332220.020
Zebrafish
regulation of immune system processGO:00026821760.020
dorsal ventral pattern formationGO:00099531330.020
Zebrafish Fly
imaginal disc growthGO:0007446370.020
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.020
oxoacid metabolic processGO:00434361030.020
regulation of microtubule based processGO:0032886490.020
regulation of hormone levelsGO:0010817400.020
purine ribonucleoside catabolic processGO:00461301120.020
cell proliferationGO:00082832990.020
protein phosphorylationGO:00064681690.020
positive regulation of neuron projection developmentGO:0010976140.020
regulation of purine nucleotide metabolic processGO:1900542620.020
regulation of localizationGO:00328792750.019
purine nucleoside metabolic processGO:00422781270.019
positive regulation of gene expressionGO:00106282900.019
regulation of microtubule cytoskeleton organizationGO:0070507410.019
positive regulation of phosphorus metabolic processGO:00105621390.019
nucleoside triphosphate catabolic processGO:00091431080.019
biological adhesionGO:00226101380.018
endomembrane system organizationGO:00102561190.018
endocrine system developmentGO:003527050.018
stem cell proliferationGO:0072089880.018
compound eye photoreceptor cell differentiationGO:00017511400.018
ventral furrow formationGO:0007370170.018
startle responseGO:0001964160.018
aromatic compound catabolic processGO:00194391660.017
organonitrogen compound catabolic processGO:19015651280.017
ion transmembrane transportGO:00342201220.017
protein transportGO:00150311550.017
cellular catabolic processGO:00442483720.017
reproductive system developmentGO:0061458740.017
positive regulation of protein metabolic processGO:00512471280.017
regulation of cell deathGO:00109411730.016
synaptic transmissionGO:00072682880.016
cellular response to organic substanceGO:00713101320.016
peptidyl amino acid modificationGO:00181931050.016
pathway restricted smad protein phosphorylationGO:006038910.016
specification of symmetryGO:0009799130.016
Zebrafish
regulation of cell cycle processGO:00105641810.016
neuroblast divisionGO:0055057350.016
epithelial structure maintenanceGO:0010669170.016
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
glycosyl compound metabolic processGO:19016571270.016
dorsal ventral axon guidanceGO:003356320.016
hematopoietic progenitor cell differentiationGO:000224410.016
regulation of cellular localizationGO:00603411360.016
regulation of apoptotic processGO:00429811300.015
glial cell migrationGO:0008347310.015
negative regulation of synapse assemblyGO:0051964390.015
neural retina developmentGO:000340740.015
apoptotic processGO:00069151590.015
regulation of programmed cell deathGO:00430671520.015
nucleoside metabolic processGO:00091161270.015
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.015
phagocytosisGO:00069092150.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
enteroendocrine cell differentiationGO:003588310.015
regulation of synapse organizationGO:00508071100.015
response to extracellular stimulusGO:00099911160.015
brain developmentGO:00074201200.015
cell cell adhesionGO:0098609260.015
apical constriction involved in gastrulationGO:000338470.015
organonitrogen compound biosynthetic processGO:19015661170.015
regulation of cellular component biogenesisGO:00440872010.015
limb developmentGO:006017310.015
axonal fasciculationGO:0007413120.015
wound healing spreading of epidermal cellsGO:003531310.015
reproductive structure developmentGO:0048608740.015
negative regulation of neurogenesisGO:0050768530.015
determination of muscle attachment siteGO:001620470.014
response to radiationGO:00093141550.014
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.014
regulation of synaptic growth at neuromuscular junctionGO:0008582890.014
negative regulation of wnt signaling pathwayGO:0030178280.014
positive regulation of transportGO:0051050920.014
positive regulation of cellular protein metabolic processGO:00322701180.014
extracellular matrix organizationGO:0030198320.014
response to alcoholGO:0097305950.014
nephron tubule developmentGO:007208030.014
negative regulation of cell deathGO:0060548810.014
regulation of pathway restricted smad protein phosphorylationGO:006039310.014
cellular hormone metabolic processGO:0034754230.014
regulation of homeostatic processGO:003284470.014
mitotic centrosome separationGO:000710080.014
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidanceGO:200030520.014
regulation of secretionGO:0051046440.014
regulation of transportGO:00510491810.014
regulation of gtpase activityGO:0043087440.013
protein catabolic processGO:00301631010.013
synaptic target recognitionGO:0008039450.013
mating behaviorGO:00076171060.013
telencephalon developmentGO:002153720.013
digestive system developmentGO:00551231490.013
Zebrafish
neurological system processGO:00508773580.013
extracellular structure organizationGO:0043062460.013
axon extension involved in axon guidanceGO:0048846100.013
positive regulation of phagocytosisGO:005076630.013
oocyte maturationGO:000155630.013
cellular response to transforming growth factor beta stimulusGO:0071560180.013
retina development in camera type eyeGO:006004140.013
kidney epithelium developmentGO:007207330.012
regulation of cell migrationGO:0030334220.012
lipid localizationGO:0010876540.012
matingGO:00076181200.012
endodermal cell differentiationGO:003598730.012
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.012
organic substance transportGO:00717022570.012
response to ethanolGO:0045471590.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
compound eye photoreceptor developmentGO:0042051780.012
spindle organizationGO:00070512530.012
detection of visible lightGO:0009584380.012
negative regulation of developmental growthGO:0048640640.012
negative regulation of bmp signaling pathwayGO:0030514120.012
rhythmic behaviorGO:0007622760.012
formation of anatomical boundaryGO:0048859370.012
negative regulation of homeostatic processGO:003284520.012
cellular response to lipidGO:0071396200.011
organelle localizationGO:00516401480.011
regulation of hemocyte proliferationGO:0035206370.011
stem cell differentiationGO:00488631170.011
regulation of immune responseGO:00507761180.011
regulation of cellular ketone metabolic processGO:001056530.011
presynaptic membrane organizationGO:009709040.011
male courtship behavior veined wing vibrationGO:0016545210.011
lymph gland developmentGO:0048542280.011
cytoskeleton dependent cytokinesisGO:0061640810.011
cellular response to endogenous stimulusGO:0071495800.011
negative regulation of protein complex disassemblyGO:0043242230.011
imaginal disc derived wing vein morphogenesisGO:0008586440.011
multicellular organism growthGO:0035264460.011
embryonic axis specificationGO:00005781070.011
Fly
hemopoiesisGO:0030097460.011
Zebrafish
striated muscle cell differentiationGO:0051146900.011
chemical homeostasisGO:0048878920.011
determination of bilateral symmetryGO:0009855130.011
Zebrafish
actin cytoskeleton reorganizationGO:0031532220.011
cellular macromolecule localizationGO:00707272200.011
pericardium developmentGO:006003920.011
regulation of cell divisionGO:0051302720.011
epiboly involved in wound healingGO:009050520.010
regulation of dendrite developmentGO:0050773370.010
negative regulation of cellular component organizationGO:00511291080.010
response to other organismGO:00517072930.010
regulation of actin cytoskeleton organizationGO:0032956420.010
protein secretionGO:0009306450.010
cognitionGO:00508901410.010
protein complex disassemblyGO:0043241360.010
positive regulation of gtpase activityGO:0043547430.010
segmentationGO:00352822070.010
Fly
positive regulation of axon guidanceGO:190266910.010
endoderm formationGO:000170630.010

tok disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart conduction diseaseDOID:1027300.052
cardiovascular system diseaseDOID:128700.052
Human
disease of anatomical entityDOID:700.052
Human