Drosophila melanogaster

88 known processes

topi (Dmel_CG8484)

matotopetli

(Aliases: CG8484,Topi,Dmel\CG8484)

topi biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatid differentiationGO:00485151140.529
spermatogenesisGO:00072832000.188
male gamete generationGO:00482322010.172
small molecule metabolic processGO:00442813050.143
positive regulation of nucleic acid templated transcriptionGO:19035082660.115
positive regulation of macromolecule metabolic processGO:00106044050.106
positive regulation of nitrogen compound metabolic processGO:00511733540.105
positive regulation of nucleobase containing compound metabolic processGO:00459353320.105
deathGO:00162652840.105
nuclear divisionGO:00002803320.088
spermatid developmentGO:0007286980.086
positive regulation of biosynthetic processGO:00098913160.086
cell divisionGO:00513012480.082
positive regulation of cellular biosynthetic processGO:00313283160.077
positive regulation of rna metabolic processGO:00512542710.065
regulation of endopeptidase activityGO:0052548360.065
programmed cell deathGO:00125012570.064
positive regulation of hydrolase activityGO:0051345780.061
positive regulation of rna biosynthetic processGO:19026802660.061
cell deathGO:00082192790.061
organophosphate metabolic processGO:00196371950.058
carbohydrate derivative metabolic processGO:19011352170.054
transcription from rna polymerase ii promoterGO:00063663680.052
apoptotic processGO:00069151590.052
ion transmembrane transportGO:00342201220.051
positive regulation of gene expressionGO:00106282900.051
positive regulation of macromolecule biosynthetic processGO:00105572830.051
meiotic nuclear divisionGO:00071261510.049
organonitrogen compound metabolic processGO:19015643180.046
cytokinesisGO:0000910900.046
nucleoside metabolic processGO:00091161270.045
sister chromatid segregationGO:0000819920.045
regulation of hydrolase activityGO:0051336970.045
chromosome organizationGO:00512763600.044
cilium assemblyGO:0042384380.044
regulation of proteolysisGO:0030162870.042
negative regulation of gene expressionGO:00106293870.040
regulation of programmed cell deathGO:00430671520.040
transmembrane transportGO:00550851390.038
single organism catabolic processGO:00447122280.038
positive regulation of endopeptidase activityGO:0010950260.038
positive regulation of cysteine type endopeptidase activityGO:2001056240.038
regulation of transcription from rna polymerase ii promoterGO:00063573780.038
organic substance catabolic processGO:19015753080.037
negative regulation of signal transductionGO:00099682060.037
organelle fusionGO:0048284460.037
positive regulation of transcription dna templatedGO:00458932660.036
cation transmembrane transportGO:0098655880.036
carboxylic acid metabolic processGO:0019752920.035
regulation of cell cycle processGO:00105641810.035
negative regulation of cell communicationGO:00106482230.035
sperm individualizationGO:0007291480.034
single organism membrane fusionGO:0044801420.034
organelle fissionGO:00482853400.034
negative regulation of cellular metabolic processGO:00313243820.034
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.034
positive regulation of cell communicationGO:00106472500.034
regulation of catalytic activityGO:00507901850.033
positive regulation of molecular functionGO:00440931360.033
regulation of cell deathGO:00109411730.033
purine nucleoside metabolic processGO:00422781270.032
cellularizationGO:0007349900.032
regulation of apoptotic processGO:00429811300.032
protein modification processGO:00362114380.032
positive regulation of catalytic activityGO:00430851180.031
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.031
cell proliferationGO:00082832990.031
cation transportGO:00068121100.031
appendage developmentGO:00487364010.031
proteolysisGO:00065081920.030
ribonucleoside metabolic processGO:00091191270.030
cellular protein modification processGO:00064644380.030
regulation of cysteine type endopeptidase activityGO:2000116270.029
purine containing compound metabolic processGO:00725211550.029
organic acid metabolic processGO:00060821030.029
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
regulation of organelle organizationGO:00330431960.029
negative regulation of macromolecule biosynthetic processGO:00105582700.028
regulation of anatomical structure morphogenesisGO:00226032420.028
cytoskeleton dependent cytokinesisGO:0061640810.028
activation of cysteine type endopeptidase activityGO:0097202170.028
positive regulation of signal transductionGO:00099672230.028
regulation of cell cycle phase transitionGO:19019871300.028
oxoacid metabolic processGO:00434361030.028
regulation of intracellular signal transductionGO:19025312360.027
vesicle mediated transportGO:00161923810.027
organelle assemblyGO:00709251980.027
regulation of cellular protein metabolic processGO:00322682430.027
spindle organizationGO:00070512530.027
glycosyl compound metabolic processGO:19016571270.027
meiotic cell cycleGO:00513211710.027
phagocytosisGO:00069092150.027
positive regulation of proteolysisGO:0045862520.026
atp metabolic processGO:0046034490.026
purine ribonucleoside metabolic processGO:00461281270.025
nucleobase containing compound catabolic processGO:00346551650.025
single organism biosynthetic processGO:00447112060.025
regulation of localizationGO:00328792750.025
nucleobase containing small molecule metabolic processGO:00550861740.025
protein maturationGO:0051604710.025
protein modification by small protein conjugationGO:0032446790.024
negative regulation of wnt signaling pathwayGO:0030178280.024
negative regulation of mitotic cell cycleGO:00459301090.024
ribonucleotide metabolic processGO:00092591450.024
negative regulation of signalingGO:00230572190.024
protein localizationGO:00081042840.024
cellular catabolic processGO:00442483720.024
protein processingGO:0016485680.024
regulation of molecular functionGO:00650092170.023
regulation of protein metabolic processGO:00512462560.023
cellular response to dna damage stimulusGO:00069742230.023
purine ribonucleoside triphosphate metabolic processGO:00092051190.023
organic substance transportGO:00717022570.023
regulation of catabolic processGO:00098941700.023
positive regulation of programmed cell deathGO:0043068620.022
catabolic processGO:00090564090.022
body morphogenesisGO:001017120.022
purine containing compound catabolic processGO:00725231120.022
regulation of response to stressGO:00801342000.021
nucleoside phosphate metabolic processGO:00067531620.021
purine nucleotide metabolic processGO:00061631460.021
developmental programmed cell deathGO:00106231380.021
proteasomal protein catabolic processGO:0010498590.021
regulation of cellular catabolic processGO:00313291570.020
purine nucleoside triphosphate metabolic processGO:00091441190.020
somatic muscle developmentGO:0007525660.020
positive regulation of cellular catabolic processGO:0031331950.020
eye developmentGO:00016543230.020
amine metabolic processGO:0009308120.020
multi multicellular organism processGO:00447061230.019
inorganic cation transmembrane transportGO:0098662610.019
cellular amine metabolic processGO:0044106120.019
purine ribonucleotide metabolic processGO:00091501450.019
heterocycle catabolic processGO:00467001660.019
negative regulation of cellular component organizationGO:00511291080.019
ubiquitin dependent protein catabolic processGO:0006511780.019
ribonucleoside triphosphate metabolic processGO:00091991190.019
nucleoside triphosphate metabolic processGO:00091411200.019
posttranscriptional regulation of gene expressionGO:00106081450.019
cell cycle checkpointGO:0000075950.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
regulation of cell cycleGO:00517262910.019
ribose phosphate metabolic processGO:00196931450.018
negative regulation of rna metabolic processGO:00512532510.018
nucleotide metabolic processGO:00091171610.018
compound eye developmentGO:00487493070.018
carbohydrate derivative catabolic processGO:19011361180.018
intracellular signal transductionGO:00355563000.018
regulation of cellular amine metabolic processGO:003323830.018
modification dependent protein catabolic processGO:0019941780.018
cellular macromolecule catabolic processGO:00442651360.018
cellular protein localizationGO:00346131600.018
aromatic compound catabolic processGO:00194391660.018
macromolecule catabolic processGO:00090571610.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.018
protein modification by small protein conjugation or removalGO:00706471060.018
meiosis iiGO:0007135230.017
purine nucleoside catabolic processGO:00061521120.017
regulation of cellular amino acid metabolic processGO:000652100.017
response to organic substanceGO:00100332840.017
organic cyclic compound catabolic processGO:19013611680.017
membrane organizationGO:00610241120.017
glycosyl compound catabolic processGO:19016581120.017
organic acid transportGO:0015849180.017
modification dependent macromolecule catabolic processGO:0043632790.017
microtubule organizing center organizationGO:00310231680.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.016
mitotic cell cycle checkpointGO:0007093880.016
positive regulation of response to stimulusGO:00485843230.016
negative regulation of cellular catabolic processGO:0031330340.016
negative regulation of cellular biosynthetic processGO:00313272770.016
regulation of protein catabolic processGO:0042176550.016
proteolysis involved in cellular protein catabolic processGO:0051603830.016
response to external biotic stimulusGO:00432072930.016
regulation of cell divisionGO:0051302720.016
segment polarity determinationGO:0007367250.016
positive regulation of intracellular signal transductionGO:19025331160.016
intracellular transportGO:00469072280.016
eye morphogenesisGO:00485922600.016
response to biotic stimulusGO:00096072940.016
histolysisGO:00075591020.016
homeostatic processGO:00425921990.016
ribonucleoside monophosphate metabolic processGO:0009161510.016
purine nucleoside triphosphate catabolic processGO:00091461080.016
regulation of mitosisGO:0007088560.016
positive regulation of signalingGO:00230562430.016
ribonucleoside catabolic processGO:00424541120.016
meiotic cell cycle processGO:19030461320.016
regulation of cellular response to stressGO:0080135890.015
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.015
chromosome separationGO:0051304420.015
purine ribonucleoside monophosphate metabolic processGO:0009167500.015
male meiosisGO:0007140520.015
carbohydrate metabolic processGO:0005975820.015
ion transportGO:00068111450.015
growthGO:00400073590.015
response to abiotic stimulusGO:00096283410.015
negative regulation of biosynthetic processGO:00098902770.015
regionalizationGO:00030024160.015
salivary gland cell autophagic cell deathGO:0035071830.015
blastoderm segmentationGO:00073501590.015
mitotic sister chromatid segregationGO:0000070870.015
regulation of transportGO:00510491810.015
embryonic pattern specificationGO:00098801740.015
single organism intracellular transportGO:19025822070.015
cellular component assembly involved in morphogenesisGO:00109271510.015
gland developmentGO:00487321910.015
ethanolamine containing compound metabolic processGO:004243940.015
negative regulation of protein metabolic processGO:0051248850.015
camera type eye developmentGO:004301040.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
response to bacteriumGO:00096171980.014
protein ubiquitinationGO:0016567700.014
compound eye morphogenesisGO:00017452490.014
regulation of phosphate metabolic processGO:00192202100.014
nucleoside monophosphate metabolic processGO:0009123520.014
response to lipopolysaccharideGO:003249640.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
mitotic cell cycle phase transitionGO:00447721380.014
positive regulation of peptidase activityGO:0010952290.014
response to alcoholGO:0097305950.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.014
nucleoside phosphate catabolic processGO:19012921100.014
regulation of peptidase activityGO:0052547390.014
nucleoside catabolic processGO:00091641120.014
monocarboxylic acid transportGO:001571830.014
imaginal disc derived wing morphogenesisGO:00074763370.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.014
embryo development ending in birth or egg hatchingGO:00097921520.014
regulation of multicellular organismal developmentGO:20000264140.014
spindle assemblyGO:0051225800.014
l amino acid importGO:004309220.014
wing disc morphogenesisGO:00074723440.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
defense response to bacteriumGO:00427421780.014
antimicrobial humoral responseGO:0019730990.014
cellular nitrogen compound catabolic processGO:00442701650.014
cellular protein catabolic processGO:0044257830.014
regulation of cell differentiationGO:00455953020.013
protein catabolic processGO:00301631010.013
negative regulation of rna biosynthetic processGO:19026792400.013
chromatin remodelingGO:0006338720.013
nucleoside triphosphate catabolic processGO:00091431080.013
regulation of phosphorus metabolic processGO:00511742100.013
regulation of microtubule based processGO:0032886490.013
synapse organizationGO:00508081960.013
imaginal disc derived appendage developmentGO:00487373990.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
negative regulation of organelle organizationGO:0010639560.013
cell cycle phase transitionGO:00447701400.013
purine ribonucleoside catabolic processGO:00461301120.013
regulation of cellular ketone metabolic processGO:001056530.013
cytoplasmic transportGO:00164821300.013
endocytosisGO:00068973100.013
nucleotide catabolic processGO:00091661090.013
positive regulation of cell deathGO:0010942690.013
purine ribonucleotide catabolic processGO:00091541090.013
regulation of epithelial cell differentiationGO:003085640.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
negative regulation of cell cycle processGO:00109481090.012
positive regulation of cellular protein metabolic processGO:00322701180.012
establishment of localization in cellGO:00516494020.012
cellular amino acid metabolic processGO:0006520610.012
negative regulation of cell cycle phase transitionGO:19019881030.012
maintenance of locationGO:0051235730.012
embryonic development via the syncytial blastodermGO:00017001480.012
gland morphogenesisGO:00226121450.012
single organism membrane organizationGO:0044802930.012
positive regulation of protein metabolic processGO:00512471280.012
exocrine system developmentGO:00352721620.012
positive regulation of phosphate metabolic processGO:00459371390.012
mitotic spindle organizationGO:00070522200.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of cell projection organizationGO:0031344920.011
metal ion transportGO:0030001740.011
positive regulation of transportGO:0051050920.011
cellular lipid metabolic processGO:0044255830.011
purine nucleotide catabolic processGO:00061951090.011
positive regulation of phosphorus metabolic processGO:00105621390.011
cellular homeostasisGO:0019725800.011
regulation of synapse organizationGO:00508071100.011
organonitrogen compound biosynthetic processGO:19015661170.011
positive regulation of nucleoside metabolic processGO:0045979470.011
forebrain developmentGO:003090020.011
response to other organismGO:00517072930.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
negative regulation of proteolysisGO:0045861310.011
inorganic ion transmembrane transportGO:0098660730.011
salivary gland developmentGO:00074311620.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
positive regulation of apoptotic processGO:0043065470.011
response to nutrient levelsGO:00316671140.011
imaginal disc derived appendage morphogenesisGO:00351143950.011
cell migrationGO:00164772380.011
salivary gland morphogenesisGO:00074351450.011
regulation of cell developmentGO:00602842150.011
organonitrogen compound catabolic processGO:19015651280.011
segmentationGO:00352822070.011
appendage morphogenesisGO:00351073970.011
axonogenesisGO:00074092900.011
response to oxygen containing compoundGO:19017002000.011
larval developmentGO:00021641040.010
positive regulation of cell motilityGO:200014730.010
telencephalon developmentGO:002153720.010
positive regulation of catabolic processGO:00098961050.010
phosphorylationGO:00163102940.010
immune responseGO:00069552460.010
post embryonic appendage morphogenesisGO:00351203850.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
intrinsic apoptotic signaling pathwayGO:0097193160.010
nitrogen compound transportGO:0071705850.010
single organism carbohydrate metabolic processGO:0044723720.010
kidney developmentGO:000182230.010
negative regulation of apoptotic processGO:0043066630.010

topi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.010