Drosophila melanogaster

79 known processes

Met (Dmel_CG1705)

Methoprene-tolerant

(Aliases: bHLHe59,Mett,met,CG1705,DmMet,Rst(1)JH,Dmel\CG1705)

Met biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of macromolecule metabolic processGO:00106044050.773
negative regulation of response to stimulusGO:00485852580.641
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.543
positive regulation of gene expressionGO:00106282900.508
transcription from rna polymerase ii promoterGO:00063663680.374
chemical homeostasisGO:0048878920.338
positive regulation of macromolecule biosynthetic processGO:00105572830.245
positive regulation of rna metabolic processGO:00512542710.241
regulation of transcription from rna polymerase ii promoterGO:00063573780.240
response to toxic substanceGO:0009636220.235
response to organophosphorusGO:004668320.233
response to endogenous stimulusGO:00097191190.231
homeostatic processGO:00425921990.216
response to insecticideGO:0017085140.213
insecticide catabolic processGO:004670110.205
toxin catabolic processGO:000940710.185
copper ion homeostasisGO:005507070.185
multi organism behaviorGO:00517051750.166
response to organic substanceGO:00100332840.164
positive regulation of rna biosynthetic processGO:19026802660.161
positive regulation of nucleobase containing compound metabolic processGO:00459353320.149
regulation of response to stressGO:00801342000.144
positive regulation of nucleic acid templated transcriptionGO:19035082660.141
organic hydroxy compound biosynthetic processGO:1901617210.133
negative regulation of signal transductionGO:00099682060.124
response to alcoholGO:0097305950.123
cellular chemical homeostasisGO:0055082400.121
epidermal growth factor receptor signaling pathwayGO:0007173580.115
negative regulation of signalingGO:00230572190.113
peptidyl amino acid modificationGO:00181931050.111
regulation of programmed cell deathGO:00430671520.107
somatic muscle developmentGO:0007525660.107
adult behaviorGO:00305341370.103
response to abiotic stimulusGO:00096283410.103
cellular response to endogenous stimulusGO:0071495800.100
positive regulation of nitrogen compound metabolic processGO:00511733540.099
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.097
response to organic cyclic compoundGO:0014070890.097
protein localizationGO:00081042840.094
regulation of phosphorus metabolic processGO:00511742100.093
actin filament based processGO:00300292200.093
aggressive behaviorGO:0002118630.091
macromolecule catabolic processGO:00090571610.089
molting cycle chitin based cuticleGO:0007591560.088
regulation of mapk cascadeGO:0043408920.088
insecticide metabolic processGO:001714320.088
protein modification processGO:00362114380.087
regulation of immune system processGO:00026821760.082
regulation of mitotic cell cycleGO:00073461900.081
regulation of cell cycleGO:00517262910.081
transmembrane transportGO:00550851390.080
cell divisionGO:00513012480.077
cellular ketone metabolic processGO:0042180240.075
single organism behaviorGO:00447083910.074
brain developmentGO:00074201200.074
mapk cascadeGO:00001651070.073
single organism cellular localizationGO:19025801800.073
response to glucoseGO:000974920.072
positive regulation of transcription dna templatedGO:00458932660.072
negative regulation of programmed cell deathGO:0043069720.071
response to hexoseGO:000974630.070
polyol biosynthetic processGO:004617330.069
regulation of blood circulationGO:1903522210.069
response to ddtGO:004668050.068
erbb signaling pathwayGO:0038127580.068
negative regulation of gene expressionGO:00106293870.068
fat soluble vitamin metabolic processGO:000677510.067
organic substance catabolic processGO:19015753080.067
immune responseGO:00069552460.066
programmed cell deathGO:00125012570.065
regulation of cell deathGO:00109411730.065
enzyme linked receptor protein signaling pathwayGO:00071671790.062
cellular homeostasisGO:0019725800.062
fat soluble vitamin biosynthetic processGO:004236210.062
defense response to bacteriumGO:00427421780.061
negative regulation of cell communicationGO:00106482230.061
response to oxygen containing compoundGO:19017002000.061
convergent extensionGO:006002620.061
response to oxidative stressGO:0006979860.061
myotube cell developmentGO:001490430.060
cellular transition metal ion homeostasisGO:004691690.060
response to alkaloidGO:0043279260.059
head developmentGO:00603221350.059
secondary metabolite catabolic processGO:009048710.059
signal transduction by phosphorylationGO:00230141070.059
regulation of catalytic activityGO:00507901850.057
response to woundingGO:0009611940.057
positive regulation of immune system processGO:0002684680.057
regulation of cellular amine metabolic processGO:003323830.057
ion transportGO:00068111450.056
protein phosphorylationGO:00064681690.056
compound eye developmentGO:00487493070.055
phosphorylationGO:00163102940.054
larval developmentGO:00021641040.053
imaginal disc derived wing morphogenesisGO:00074763370.053
negative regulation of cell deathGO:0060548810.052
positive regulation of cellular biosynthetic processGO:00313283160.052
response to bacteriumGO:00096171980.052
positive regulation of response to stimulusGO:00485843230.051
regulation of cellular protein metabolic processGO:00322682430.050
taxisGO:00423303040.049
tube developmentGO:00352952440.049
defense responseGO:00069523000.049
actin filament based movementGO:0030048260.049
regulation of erbb signaling pathwayGO:1901184420.049
protein transportGO:00150311550.048
proteolysisGO:00065081920.047
single organism biosynthetic processGO:00447112060.046
regulation of anatomical structure sizeGO:00900661630.046
regulation of proteolysisGO:0030162870.046
regulation of protein metabolic processGO:00512462560.045
epithelial cell developmentGO:00020642740.045
negative regulation of cellular protein metabolic processGO:0032269850.045
regulation of intracellular signal transductionGO:19025312360.045
transition metal ion homeostasisGO:0055076170.044
imaginal disc derived appendage morphogenesisGO:00351143950.044
oxoacid metabolic processGO:00434361030.043
regulation of cellular ketone metabolic processGO:001056530.043
actin cytoskeleton organizationGO:00300362060.043
response to extracellular stimulusGO:00099911160.042
negative regulation of protein metabolic processGO:0051248850.042
cell maturationGO:00484691440.042
mushroom body developmentGO:0016319700.042
regulation of phosphate metabolic processGO:00192202100.041
cellular response to dna damage stimulusGO:00069742230.041
deathGO:00162652840.041
response to organonitrogen compoundGO:0010243750.041
neurological system processGO:00508773580.041
neuron projection guidanceGO:00974852410.040
cellular response to chemical stimulusGO:00708871990.040
locomotor rhythmGO:0045475560.039
cellular protein modification processGO:00064644380.039
intracellular transportGO:00469072280.039
actin filament bundle organizationGO:0061572280.038
response to biotic stimulusGO:00096072940.038
wing disc morphogenesisGO:00074723440.038
positive regulation of biosynthetic processGO:00098913160.038
regulation of apoptotic processGO:00429811300.037
cellular macromolecule catabolic processGO:00442651360.037
lipid homeostasisGO:0055088330.037
cellular response to fibroblast growth factor stimulusGO:0044344100.037
peptidyl threonine phosphorylationGO:001810720.037
eye morphogenesisGO:00485922600.037
regulation of actin filament based processGO:0032970420.036
activation of innate immune responseGO:000221840.036
regulation of catabolic processGO:00098941700.036
cellular catabolic processGO:00442483720.035
response to other organismGO:00517072930.035
regulation of cellular localizationGO:00603411360.035
metal ion transportGO:0030001740.035
chromatin organizationGO:00063252070.035
secretionGO:00469031090.035
medium chain fatty acid metabolic processGO:005179110.035
toxin metabolic processGO:000940420.035
anion transmembrane transportGO:0098656260.035
regulation of immune responseGO:00507761180.035
cellular response to oxygen containing compoundGO:1901701790.035
histone modificationGO:00165701060.034
organic substance transportGO:00717022570.034
regulation of cell proliferationGO:00421271630.034
regulation of cellular amino acid metabolic processGO:000652100.034
regulation of protein kinase activityGO:0045859510.034
regulation of phosphorylationGO:00423251470.034
cellular response to organic substanceGO:00713101320.033
amine metabolic processGO:0009308120.033
negative regulation of erbb signaling pathwayGO:1901185290.032
compound eye morphogenesisGO:00017452490.032
tube morphogenesisGO:00352391910.032
carbohydrate metabolic processGO:0005975820.031
stress activated mapk cascadeGO:0051403520.031
positive regulation of cell motilityGO:200014730.031
chromatin modificationGO:00165681470.031
response to purine containing compoundGO:0014074120.030
vitamin biosynthetic processGO:000911010.030
spermatogenesisGO:00072832000.030
positive regulation of protein kinase activityGO:0045860250.030
cellular response to hexose stimulusGO:007133110.030
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.030
cell deathGO:00082192790.030
inter male aggressive behaviorGO:0002121600.029
agingGO:00075681430.029
cellular ion homeostasisGO:0006873390.029
positive regulation of signal transductionGO:00099672230.029
cellular response to monosaccharide stimulusGO:007132620.029
regulation of cytoskeleton organizationGO:0051493890.029
innate immune responseGO:00450871440.029
circadian behaviorGO:0048512760.029
muscle cell differentiationGO:00426921030.028
covalent chromatin modificationGO:00165691060.028
positive regulation of mapk cascadeGO:0043410630.028
response to monosaccharideGO:003428440.028
cytokinesisGO:0000910900.028
immune response activating signal transductionGO:000275720.028
actin filament bundle assemblyGO:0051017260.028
localization of cellGO:00516742570.027
response to nitrogen compoundGO:1901698900.027
actin filament organizationGO:00070151260.026
positive regulation of phosphorylationGO:0042327870.026
skeletal muscle fiber developmentGO:004874130.026
secretion by cellGO:00329401010.026
cellular response to organonitrogen compoundGO:0071417360.026
single organism catabolic processGO:00447122280.026
female meiotic divisionGO:0007143700.026
response to growth factorGO:0070848310.026
negative regulation of phosphorylationGO:0042326350.026
cellular response to carbohydrate stimulusGO:007132240.026
positive regulation of cell migrationGO:003033520.026
purine nucleotide catabolic processGO:00061951090.026
hindbrain developmentGO:003090220.025
protein catabolic processGO:00301631010.025
immune response regulating signaling pathwayGO:000276420.025
carboxylic acid metabolic processGO:0019752920.025
regulation of peptidase activityGO:0052547390.025
regulation of molecular functionGO:00650092170.025
negative regulation of protein modification processGO:0031400290.024
appendage developmentGO:00487364010.024
intracellular signal transductionGO:00355563000.024
regulation of kinase activityGO:0043549530.024
regulation of insulin receptor signaling pathwayGO:0046626170.024
sensory perception of smellGO:0007608800.024
protein complex biogenesisGO:00702712010.024
establishment of protein localizationGO:00451841630.024
dendrite developmentGO:00163582040.024
sensory organ morphogenesisGO:00905962600.023
regulation of transferase activityGO:0051338580.023
proteasomal protein catabolic processGO:0010498590.023
instar larval developmentGO:0002168550.023
signal releaseGO:0023061490.023
positive regulation of cell communicationGO:00106472500.023
central nervous system developmentGO:00074172010.023
dendrite morphogenesisGO:00488131990.023
negative regulation of cellular metabolic processGO:00313243820.023
kidney morphogenesisGO:006099330.023
axonogenesisGO:00074092900.023
regulation of stress activated mapk cascadeGO:0032872410.023
cytoplasmic transportGO:00164821300.023
regulation of protein modification processGO:00313991120.022
single organism intracellular transportGO:19025822070.022
response to hormoneGO:0009725450.022
response to carbohydrateGO:0009743150.022
regulation of cellular response to stressGO:0080135890.022
membrane depolarizationGO:005189940.022
positive regulation of phosphorus metabolic processGO:00105621390.022
metal ion homeostasisGO:0055065440.022
regulation of protein transportGO:0051223570.022
sister chromatid segregationGO:0000819920.022
positive regulation of phosphate metabolic processGO:00459371390.022
nucleus localizationGO:0051647340.022
cognitionGO:00508901410.022
locomotory behaviorGO:00076261760.021
regulation of cell cycle processGO:00105641810.021
cell proliferationGO:00082832990.021
regulation of endopeptidase activityGO:0052548360.021
cell migrationGO:00164772380.021
alcohol biosynthetic processGO:0046165140.021
growthGO:00400073590.021
stress activated protein kinase signaling cascadeGO:0031098550.021
immune system processGO:00023763470.021
regulation of nervous system developmentGO:00519602480.021
positive regulation of protein phosphorylationGO:0001934340.021
salivary gland developmentGO:00074311620.021
embryonic morphogenesisGO:00485982060.020
regulation of hydrolase activityGO:0051336970.020
steroid catabolic processGO:000670610.020
secondary metabolic processGO:0019748750.020
regulation of stress activated protein kinase signaling cascadeGO:0070302420.020
lipopolysaccharide mediated signaling pathwayGO:003166310.020
regulation of transportGO:00510491810.020
organelle assemblyGO:00709251980.020
male courtship behavior veined wing vibrationGO:0016545210.020
response to mercury ionGO:004668930.020
eye photoreceptor cell developmentGO:0042462810.020
rhythmic behaviorGO:0007622760.020
catabolic processGO:00090564090.020
kidney developmentGO:000182230.020
muscle structure developmentGO:00610612240.020
negative regulation of catalytic activityGO:0043086420.020
mrna metabolic processGO:00160711240.019
regulation of excitatory postsynaptic membrane potentialGO:006007930.019
learning or memoryGO:00076111410.019
chromosome segregationGO:00070591570.019
carbohydrate biosynthetic processGO:0016051170.019
regulation of cellular response to growth factor stimulusGO:0090287130.019
regulation of system processGO:0044057360.019
skeletal muscle organ developmentGO:0060538480.019
reproductive behaviorGO:00190981220.019
mitotic nuclear divisionGO:00070672130.018
single organism carbohydrate metabolic processGO:0044723720.018
positive regulation of transferase activityGO:0051347260.018
muscle organ developmentGO:00075171270.018
regulation of circadian rhythmGO:0042752490.018
maintenance of locationGO:0051235730.018
ion transmembrane transportGO:00342201220.018
convergent extension involved in gastrulationGO:006002720.018
regulation of innate immune responseGO:0045088710.018
cellular amine metabolic processGO:0044106120.018
positive regulation of protein import into nucleusGO:0042307210.018
columnar cuboidal epithelial cell differentiationGO:00020652560.017
positive regulation of cellular protein metabolic processGO:00322701180.017
chromosome organizationGO:00512763600.017
anion homeostasisGO:005508130.017
memoryGO:0007613940.017
macromolecular complex assemblyGO:00650032560.017
purine nucleotide metabolic processGO:00061631460.017
nucleoside triphosphate metabolic processGO:00091411200.017
cellular response to nitrogen compoundGO:1901699510.017
anatomical structure homeostasisGO:0060249970.017
nuclear body organizationGO:003057560.017
axon guidanceGO:00074112330.017
negative regulation of cell cell adhesionGO:002240880.017
epithelium migrationGO:00901321480.017
positive regulation of protein secretionGO:005071490.017
imaginal disc eversionGO:000756140.017
lipid biosynthetic processGO:0008610460.017
exocrine system developmentGO:00352721620.017
post embryonic appendage morphogenesisGO:00351203850.017
endomembrane system organizationGO:00102561190.017
regulation of protein phosphorylationGO:0001932640.017
regulation of defense responseGO:00313471020.016
imaginal disc derived appendage developmentGO:00487373990.016
positive regulation of catalytic activityGO:00430851180.016
positive regulation of lipid metabolic processGO:004583440.016
positive regulation of autophagyGO:0010508210.016
defense response to other organismGO:00985422250.016
protein complex assemblyGO:00064612000.016
negative regulation of biosynthetic processGO:00098902770.016
response to fibroblast growth factorGO:0071774100.016
regulation of tube sizeGO:0035150460.016
response to ethanolGO:0045471590.016
response to external biotic stimulusGO:00432072930.016
regulation of localizationGO:00328792750.016
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.016
response to sterolGO:0036314340.016
negative regulation of epithelial cell proliferationGO:005068040.016
gland morphogenesisGO:00226121450.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
regulation of organelle organizationGO:00330431960.016
peptidyl threonine modificationGO:001821030.015
protein secretionGO:0009306450.015
negative regulation of cellular response to oxidative stressGO:190040810.015
cellular macromolecular complex assemblyGO:00346221530.015
cation transportGO:00068121100.015
negative regulation of proteolysisGO:0045861310.015
mitotic cytokinesisGO:0000281500.015
chemotaxisGO:00069352490.015
eye developmentGO:00016543230.015
camera type eye developmentGO:004301040.015
positive regulation of protein transportGO:0051222370.015
neural retina developmentGO:000340740.015
response to anestheticGO:007234790.015
regulation of cell junction assemblyGO:190188820.015
positive regulation of protein modification processGO:0031401580.015
oxidation reduction processGO:00551141230.015
rna processingGO:00063961470.015
positive regulation of programmed cell deathGO:0043068620.015
positive regulation of nucleocytoplasmic transportGO:0046824240.015
vitamin metabolic processGO:000676620.015
nucleocytoplasmic transportGO:0006913720.015
small molecule biosynthetic processGO:0044283370.014
cellular macromolecule localizationGO:00707272200.014
regulation of stem cell proliferationGO:0072091400.014
smoothened signaling pathwayGO:0007224490.014
steroid biosynthetic processGO:0006694160.014
photoreceptor cell differentiationGO:00465301700.014
nitrogen compound transportGO:0071705850.014
lauric acid metabolic processGO:004825210.014
positive regulation of immune responseGO:0050778630.014
response to caffeineGO:0031000120.014
protein acylationGO:0043543420.014
cellular protein catabolic processGO:0044257830.014
positive regulation of kinase activityGO:0033674250.014
regulation of epithelial cell proliferationGO:005067840.014
dorsal ventral axis specificationGO:0009950660.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
regulation of protein localizationGO:0032880760.014
retina development in camera type eyeGO:006004140.014
lipid metabolic processGO:00066291210.013
regulation of cellular response to oxidative stressGO:190040740.013
cholesterol homeostasisGO:004263230.013
negative regulation of cell cycleGO:00457861160.013
cellular response to oxidative stressGO:0034599280.013
connective tissue developmentGO:006144830.013
response to xenobiotic stimulusGO:000941050.013
male courtship behavior veined wing generated song productionGO:0045433200.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
digestive system developmentGO:00551231490.013
response to insulinGO:0032868290.013
response to lipopolysaccharideGO:003249640.013
regulation of response to oxidative stressGO:190288240.013
negative regulation of cell cycle processGO:00109481090.013
developmental growthGO:00485892800.013
negative regulation of intracellular signal transductionGO:1902532570.013
regulation of cellular protein catabolic processGO:1903362440.013
regulation of secretionGO:0051046440.013
body morphogenesisGO:001017120.013
oocyte differentiationGO:00099941450.013
organ growthGO:0035265560.013
negative regulation of organelle organizationGO:0010639560.013
regulation of intracellular transportGO:0032386640.012
photoreceptor cell fate specificationGO:004370490.012
vesicle mediated transportGO:00161923810.012
posttranscriptional gene silencing by rnaGO:0035194450.012
branching involved in open tracheal system developmentGO:0060446450.012
regulation of protein serine threonine kinase activityGO:0071900250.012
regulation of cellular catabolic processGO:00313291570.012
regulation of protein processingGO:0070613320.012
positive regulation of organelle organizationGO:0010638650.012
regulation of steroid metabolic processGO:001921820.012
compound eye cone cell differentiationGO:0042675130.012
gene silencing by rnaGO:0031047570.012
cellular response to growth factor stimulusGO:0071363300.012
jnk cascadeGO:0007254500.012
outflow tract morphogenesisGO:000315140.012
spindle assemblyGO:0051225800.012
cellular metal ion homeostasisGO:0006875310.012
positive regulation of epithelial cell differentiationGO:003085810.012
embryonic hemopoiesisGO:0035162260.012
garland nephrocyte differentiationGO:006132130.012
negative regulation of response to oxidative stressGO:190288310.012
purine nucleoside monophosphate metabolic processGO:0009126500.012
molting cycleGO:0042303560.011
regulation of sequestering of calcium ionGO:005128230.011
phagocytosisGO:00069092150.011
organic hydroxy compound metabolic processGO:1901615830.011
epithelial cell differentiationGO:00308553220.011
cellular response to molecule of bacterial originGO:007121930.011
xenobiotic catabolic processGO:004217810.011
blastoderm segmentationGO:00073501590.011
protein maturationGO:0051604710.011
positive regulation of cell deathGO:0010942690.011
regulation of cell sizeGO:0008361630.011
positive regulation of jun kinase activityGO:004350740.011
sarcomere organizationGO:0045214260.011
hormone biosynthetic processGO:0042446200.011
cellular cation homeostasisGO:0030003380.011
positive regulation of cell cycleGO:0045787430.011
negative regulation of mitotic cell cycleGO:00459301090.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
generation of precursor metabolites and energyGO:0006091420.011
negative regulation of cellular response to growth factor stimulusGO:009028860.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
epithelial tube morphogenesisGO:0060562880.011
negative regulation of phosphorus metabolic processGO:0010563450.011
regulation of dna metabolic processGO:0051052340.010
nucleoside phosphate metabolic processGO:00067531620.010
regionalizationGO:00030024160.010
positive regulation of protein serine threonine kinase activityGO:0071902150.010
cell cycle phase transitionGO:00447701400.010
hematopoietic progenitor cell differentiationGO:000224410.010
determination of genital disc primordiumGO:0035225100.010
positive regulation of intracellular signal transductionGO:19025331160.010
multicellular organismal homeostasisGO:0048871410.010
negative regulation of phosphate metabolic processGO:0045936450.010
chitin based cuticle developmentGO:0040003490.010
negative regulation of nervous system developmentGO:0051961920.010
cell adhesionGO:00071551360.010
microtubule cytoskeleton organization involved in mitosisGO:1902850520.010
release of sequestered calcium ion into cytosolGO:005120910.010
transition metal ion transportGO:0000041160.010

Met disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.170
hypertensionDOID:1076300.170
artery diseaseDOID:005082800.170
vascular diseaseDOID:17800.170
disease of anatomical entityDOID:700.170
essential hypertensionDOID:1082500.170
auditory system diseaseDOID:274200.040
nervous system diseaseDOID:86300.040
sensory system diseaseDOID:005015500.040
disease of metabolismDOID:001466700.023
acquired metabolic diseaseDOID:006015800.023
musculoskeletal system diseaseDOID:1700.012
glucose metabolism diseaseDOID:419400.012
type 2 diabetes mellitusDOID:935200.012
diabetes mellitusDOID:935100.012
carbohydrate metabolism diseaseDOID:005001300.012