IMP: Integrative Multi-species Prediction

Drosophila melanogaster

10 known processes

mRpL12 (Dmel_CG5012)

mitochondrial ribosomal protein L12

(Aliases: L7/L12,L7/12A,Dmel\CG5012,l(3)rL424,l(3)10534,L7,l(3)j4B2,CG5012,mRpL7-L12,Mrp17,BcDNA:RE53508)

FLYBASE: FBgn0011787
Entrez: 44326
UniProtKB: Q9VSR5

Process Predictions
Disease Predictions

mRpL12 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
growth	GO:0040007	359	0.223
endocytosis	GO:0006897	310	0.178
embryo development ending in birth or egg hatching	GO:0009792	152	0.078
response to abiotic stimulus	GO:0009628	341	0.062
larval development	GO:0002164	104	0.059
dna metabolic process	GO:0006259	227	0.058
vesicle mediated transport	GO:0016192	381	0.053
small molecule metabolic process	GO:0044281	305	0.051
single organism catabolic process	GO:0044712	228	0.045
organonitrogen compound metabolic process	GO:1901564	318	0.045
regulation of growth	GO:0040008	233	0.042
catabolic process	GO:0009056	409	0.039
regulation of response to stress	GO:0080134	200	0.035
cell death	GO:0008219	279	0.034
response to oxygen containing compound	GO:1901700	200	0.033
nucleoside phosphate metabolic process	GO:0006753	162	0.032
response to other organism	GO:0051707	293	0.031
negative regulation of response to stimulus	GO:0048585	258	0.031
programmed cell death	GO:0012501	257	0.029
positive regulation of growth	GO:0045927	75	0.026
cell proliferation	GO:0008283	299	0.026
protein complex biogenesis	GO:0070271	201	0.025
nucleotide metabolic process	GO:0009117	161	0.024
phagocytosis	GO:0006909	215	0.024
response to biotic stimulus	GO:0009607	294	0.023
response to bacterium	GO:0009617	198	0.023
intracellular signal transduction	GO:0035556	300	0.023
carboxylic acid metabolic process	GO:0019752	92	0.023
atp metabolic process	GO:0046034	49	0.023
immune system process	GO:0002376	347	0.023
ribonucleotide metabolic process	GO:0009259	145	0.022
death	GO:0016265	284	0.021
nucleobase containing small molecule metabolic process	GO:0055086	174	0.021
cellular catabolic process	GO:0044248	372	0.021
organic acid metabolic process	GO:0006082	103	0.020
regulation of multicellular organism growth	GO:0040014	40	0.020
response to organic substance	GO:0010033	284	0.019
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.018
ribose phosphate metabolic process	GO:0019693	145	0.018
heterocycle catabolic process	GO:0046700	166	0.018
developmental growth	GO:0048589	280	0.018
oxoacid metabolic process	GO:0043436	103	0.018
purine nucleotide metabolic process	GO:0006163	146	0.017
spindle assembly	GO:0051225	80	0.017
organophosphate metabolic process	GO:0019637	195	0.017
organic substance transport	GO:0071702	257	0.017
fatty acid metabolic process	GO:0006631	20	0.017
regulation of hydrolase activity	GO:0051336	97	0.016
regulation of cellular protein metabolic process	GO:0032268	243	0.016
defense response to bacterium	GO:0042742	178	0.016
response to external biotic stimulus	GO:0043207	293	0.016
anatomical structure homeostasis	GO:0060249	97	0.016
single organism behavior	GO:0044708	391	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
organophosphate catabolic process	GO:0046434	112	0.016
receptor mediated endocytosis	GO:0006898	21	0.015
regulation of developmental growth	GO:0048638	174	0.015
purine nucleotide catabolic process	GO:0006195	109	0.015
nuclear division	GO:0000280	332	0.015
regulation of molecular function	GO:0065009	217	0.014
purine ribonucleotide metabolic process	GO:0009150	145	0.014
response to starvation	GO:0042594	97	0.014
gland development	GO:0048732	191	0.014
chromatin organization	GO:0006325	207	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
phosphorylation	GO:0016310	294	0.013
protein localization	GO:0008104	284	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
chaperone mediated protein transport	GO:0072321	1	0.013
organic substance catabolic process	GO:1901575	308	0.013
purine nucleoside metabolic process	GO:0042278	127	0.013
organelle fission	GO:0048285	340	0.013
purine containing compound catabolic process	GO:0072523	112	0.013
meiotic nuclear division	GO:0007126	151	0.013
defense response to other organism	GO:0098542	225	0.013
protein complex assembly	GO:0006461	200	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
ribonucleotide catabolic process	GO:0009261	109	0.012
nucleotide catabolic process	GO:0009166	109	0.012
establishment of localization in cell	GO:0051649	402	0.012
germ cell migration	GO:0008354	43	0.012
protein transport	GO:0015031	155	0.012
establishment of protein localization	GO:0045184	163	0.012
positive regulation of hydrolase activity	GO:0051345	78	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
spindle organization	GO:0007051	253	0.012
defense response	GO:0006952	300	0.012
dna replication	GO:0006260	48	0.012
trna transcription from rna polymerase iii promoter	GO:0042797	1	0.012
mitotic nuclear division	GO:0007067	213	0.011
negative regulation of cell death	GO:0060548	81	0.011
mitochondrion organization	GO:0007005	65	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
response to temperature stimulus	GO:0009266	106	0.011
development of primary sexual characteristics	GO:0045137	50	0.011
sex differentiation	GO:0007548	81	0.011
transmembrane transport	GO:0055085	139	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
localization of cell	GO:0051674	257	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.010
regulation of cellular ketone metabolic process	GO:0010565	3	0.010
regulation of catabolic process	GO:0009894	170	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010
internal protein amino acid acetylation	GO:0006475	38	0.010
response to nutrient levels	GO:0031667	114	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
cellular response to chemical stimulus	GO:0070887	199	0.010
muscle tissue morphogenesis	GO:0060415	2	0.010
ribonucleoside metabolic process	GO:0009119	127	0.010
regulation of immune response	GO:0050776	118	0.010
regulation of immune system process	GO:0002682	176	0.010
apoptotic process	GO:0006915	159	0.010
regulation of cell death	GO:0010941	173	0.010
positive regulation of catalytic activity	GO:0043085	118	0.010

mRpL12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.025
disease of cellular proliferation	DOID:14566	0.012
disease of anatomical entity	DOID:7	0.011

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