Drosophila melanogaster

115 known processes

wee (Dmel_CG4488)

CG4488 gene product from transcript CG4488-RA

(Aliases: dwee1,Wee,Dmel\CG4488,CG4488,Wee1,Wee 1,WEE1,dWee1,Dwee,wee1,Dwee1)

wee biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuromuscular junction developmentGO:00075281490.658
negative regulation of cell cycleGO:00457861160.657
organelle fissionGO:00482853400.557
nuclear divisionGO:00002803320.552
regulation of cell cycle phase transitionGO:19019871300.529
negative regulation of mitotic cell cycle phase transitionGO:19019911030.451
negative regulation of mitotic cell cycleGO:00459301090.449
oocyte developmentGO:00485991240.419
Mouse
embryo development ending in birth or egg hatchingGO:00097921520.395
cell cycle checkpointGO:0000075950.392
regulation of cell deathGO:00109411730.376
regulation of mitotic cell cycle phase transitionGO:19019901300.354
immune responseGO:00069552460.331
synaptic transmissionGO:00072682880.319
negative regulation of cell cycle processGO:00109481090.314
regulation of programmed cell deathGO:00430671520.309
regulation of cell differentiationGO:00455953020.303
Mouse
synapse organizationGO:00508081960.299
cell divisionGO:00513012480.294
Mouse
negative regulation of cell cycle phase transitionGO:19019881030.291
negative regulation of translationGO:0017148280.290
protein modification processGO:00362114380.267
spindle assemblyGO:0051225800.259
larval developmentGO:00021641040.255
transcription from rna polymerase ii promoterGO:00063663680.250
mitotic dna integrity checkpointGO:0044774750.247
mitotic cell cycle phase transitionGO:00447721380.245
dna integrity checkpointGO:0031570810.243
positive regulation of macromolecule metabolic processGO:00106044050.230
cell deathGO:00082192790.225
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.213
programmed cell deathGO:00125012570.210
protein modification by small protein conjugationGO:0032446790.203
single fertilizationGO:0007338240.199
Mouse
cellular macromolecule localizationGO:00707272200.198
nucleus organizationGO:0006997450.175
Mouse
regulation of synaptic growth at neuromuscular junctionGO:0008582890.174
oocyte maturationGO:000155630.169
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.169
regionalizationGO:00030024160.169
cellular macromolecule catabolic processGO:00442651360.163
negative regulation of biosynthetic processGO:00098902770.157
tube developmentGO:00352952440.156
chromosome organizationGO:00512763600.137
digestive system developmentGO:00551231490.130
deathGO:00162652840.130
positive regulation of developmental processGO:00510941430.129
cellular protein modification processGO:00064644380.127
dna templated transcription elongationGO:0006354180.126
fertilizationGO:0009566260.120
Mouse
negative regulation of cellular metabolic processGO:00313243820.116
negative regulation of neuron deathGO:1901215180.114
mitotic dna damage checkpointGO:0044773740.113
stem cell divisionGO:0017145690.111
endocytosisGO:00068973100.109
immune system processGO:00023763470.103
protein modification by small protein conjugation or removalGO:00706471060.101
cell proliferationGO:00082832990.101
regulation of cell divisionGO:0051302720.101
Mouse
regulation of cell cycle processGO:00105641810.100
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233250.100
female meiotic divisionGO:0007143700.100
Mouse
protein complex biogenesisGO:00702712010.097
positive regulation of rna metabolic processGO:00512542710.096
mrna metabolic processGO:00160711240.094
determination of adult lifespanGO:00083401370.092
mitotic spindle organizationGO:00070522200.091
taxisGO:00423303040.091
chromosome segregationGO:00070591570.091
single organism biosynthetic processGO:00447112060.086
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.085
regulation of multicellular organismal developmentGO:20000264140.085
male gamete generationGO:00482322010.084
mitotic sister chromatid segregationGO:0000070870.082
cell cycle phase transitionGO:00447701400.082
organic acid metabolic processGO:00060821030.079
centrosome organizationGO:00512971630.078
catabolic processGO:00090564090.078
negative regulation of macromolecule biosynthetic processGO:00105582700.078
intracellular signal transductionGO:00355563000.077
regulation of cell cycleGO:00517262910.076
mitotic cell cycle checkpointGO:0007093880.076
protein phosphorylationGO:00064681690.075
digestive tract morphogenesisGO:00485461270.074
synapse assemblyGO:00074161430.071
dendrite developmentGO:00163582040.070
digestive tract developmentGO:00485651490.069
negative regulation of nucleic acid templated transcriptionGO:19035072400.067
meiotic cell cycleGO:00513211710.067
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.066
meiotic cell cycle processGO:19030461320.065
Mouse
regulation of synapse structure and activityGO:00508031280.065
dendrite morphogenesisGO:00488131990.064
apoptotic processGO:00069151590.064
establishment of localization in cellGO:00516494020.064
pole cell developmentGO:0007277260.064
positive regulation of multicellular organismal processGO:00512401430.063
phosphorylationGO:00163102940.063
synaptic growth at neuromuscular junctionGO:00511241190.062
jnk cascadeGO:0007254500.061
cytoplasmic microtubule organizationGO:0031122220.060
regulation of apoptotic processGO:00429811300.059
molting cycleGO:0042303560.059
positive regulation of rna biosynthetic processGO:19026802660.059
protein targeting to nucleusGO:0044744510.059
positive regulation of catabolic processGO:00098961050.058
regulation of synapse organizationGO:00508071100.058
regulation of molecular functionGO:00650092170.057
tube morphogenesisGO:00352391910.057
regulation of mitotic cell cycleGO:00073461900.056
compound eye developmentGO:00487493070.056
positive regulation of nucleic acid templated transcriptionGO:19035082660.056
meiotic spindle organizationGO:0000212360.055
signal transduction in response to dna damageGO:004277030.055
single organism intracellular transportGO:19025822070.055
regulation of protein metabolic processGO:00512462560.054
centrosome duplicationGO:00512981210.054
regulation of phosphorylationGO:00423251470.053
regulation of mapk cascadeGO:0043408920.053
response to biotic stimulusGO:00096072940.052
asymmetric neuroblast divisionGO:0055059330.051
response to other organismGO:00517072930.051
protein catabolic processGO:00301631010.051
regulation of i kappab kinase nf kappab signalingGO:004312220.050
regulation of meiosisGO:004002030.050
Mouse
negative regulation of gene expressionGO:00106293870.049
spindle assembly involved in female meiosisGO:0007056140.049
regulation of cell developmentGO:00602842150.049
Mouse
organelle localizationGO:00516401480.047
multicellular organismal agingGO:00102591400.047
regulation of nervous system developmentGO:00519602480.045
response to oxidative stressGO:0006979860.045
regulation of epithelial cell proliferationGO:005067840.045
intracellular transportGO:00469072280.045
eye morphogenesisGO:00485922600.045
eye developmentGO:00016543230.044
growthGO:00400073590.044
regulation of stress activated mapk cascadeGO:0032872410.044
negative regulation of programmed cell deathGO:0043069720.044
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.044
oxoacid metabolic processGO:00434361030.044
proteolysisGO:00065081920.043
vesicle mediated transportGO:00161923810.043
embryonic morphogenesisGO:00485982060.042
spindle organizationGO:00070512530.042
response to uvGO:0009411240.042
regulation of transcription from rna polymerase ii promoterGO:00063573780.042
hemopoiesisGO:0030097460.041
macromolecule catabolic processGO:00090571610.041
positive regulation of phosphorylationGO:0042327870.040
organic substance catabolic processGO:19015753080.040
negative regulation of chromosome segregationGO:0051985140.040
mitotic nuclear divisionGO:00070672130.040
positive regulation of mitotic sister chromatid separationGO:1901970100.040
agingGO:00075681430.039
proteasomal protein catabolic processGO:0010498590.039
response to external biotic stimulusGO:00432072930.039
cellular response to chemical stimulusGO:00708871990.037
axon guidanceGO:00074112330.037
positive regulation of cell proliferationGO:0008284470.037
positive regulation of cell deathGO:0010942690.036
positive regulation of i kappab kinase nf kappab signalingGO:004312310.036
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.036
positive regulation of phosphorus metabolic processGO:00105621390.036
histoblast morphogenesisGO:000748890.035
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.035
single organism nuclear importGO:1902593510.034
lateral inhibitionGO:00463312060.034
response to abiotic stimulusGO:00096283410.034
cell type specific apoptotic processGO:0097285380.033
regulation of transferase activityGO:0051338580.033
positive regulation of nucleobase containing compound metabolic processGO:00459353320.033
developmental maturationGO:00217001720.033
Mouse
nucleocytoplasmic transportGO:0006913720.032
dorsal ventral pattern formationGO:00099531330.031
spindle assembly involved in mitosisGO:0090307500.031
intracellular mrna localization involved in pattern specification processGO:0060810560.031
positive regulation of proteasomal protein catabolic processGO:1901800200.031
positive regulation of phosphate metabolic processGO:00459371390.031
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.031
positive regulation of transcription dna templatedGO:00458932660.031
peptidyl amino acid modificationGO:00181931050.031
homeostatic processGO:00425921990.030
protein ubiquitinationGO:0016567700.030
mitotic sister chromatid separationGO:0051306300.030
regulation of ras protein signal transductionGO:0046578930.030
transcription elongation from rna polymerase ii promoterGO:0006368180.030
regulation of cellular localizationGO:00603411360.030
regulation of chromosome segregationGO:0051983320.030
positive regulation of proteolysisGO:0045862520.030
nuclear transportGO:0051169720.030
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.030
protein localizationGO:00081042840.029
compound eye morphogenesisGO:00017452490.029
protein complex assemblyGO:00064612000.029
asymmetric stem cell divisionGO:0098722490.029
membrane organizationGO:00610241120.029
cellular catabolic processGO:00442483720.028
positive regulation of cell cycleGO:0045787430.028
regulation of transportGO:00510491810.028
positive regulation of protein catabolic processGO:0045732340.028
regulation of kinase activityGO:0043549530.028
dna metabolic processGO:00062592270.028
modification dependent protein catabolic processGO:0019941780.028
regulation of phosphate metabolic processGO:00192202100.027
cell maturationGO:00484691440.027
Mouse
sensory organ morphogenesisGO:00905962600.027
karyogamyGO:000074140.027
g2 m transition of mitotic cell cycleGO:0000086190.027
regulation of immune responseGO:00507761180.026
cellular nitrogen compound catabolic processGO:00442701650.026
mitotic g2 m transition checkpointGO:0044818700.026
nuclear envelope organizationGO:000699870.026
regulation of multi organism processGO:00439001310.026
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.026
single organism cellular localizationGO:19025801800.026
sister chromatid segregationGO:0000819920.026
negative regulation of cell deathGO:0060548810.025
segmentationGO:00352822070.025
cellular protein localizationGO:00346131600.025
apoptotic signaling pathwayGO:0097190270.025
translationGO:0006412690.024
regulation of immune system processGO:00026821760.024
negative regulation of apoptotic processGO:0043066630.024
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
intracellular protein transportGO:00068861040.024
signal transduction by p53 class mediatorGO:007233160.024
membrane disassemblyGO:003039740.024
negative regulation of cellular protein metabolic processGO:0032269850.023
cellular protein catabolic processGO:0044257830.023
pole cell formationGO:0007279190.023
mitotic cell cycle embryonicGO:0045448380.023
cellular protein complex assemblyGO:0043623710.022
positive regulation of molecular functionGO:00440931360.022
ubiquitin dependent protein catabolic processGO:0006511780.022
positive regulation of macromolecule biosynthetic processGO:00105572830.022
single organism carbohydrate metabolic processGO:0044723720.022
regulation of nuclear divisionGO:0051783580.022
Mouse
organic substance transportGO:00717022570.022
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.022
positive regulation of apoptotic processGO:0043065470.021
gastrulationGO:0007369700.021
regulation of developmental growthGO:00486381740.021
response to organic substanceGO:00100332840.021
regulation of mitosisGO:0007088560.021
pronuclear fusionGO:000734440.020
positive regulation of protein modification processGO:0031401580.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
chemotaxisGO:00069352490.020
positive regulation of transportGO:0051050920.020
regulation of protein catabolic processGO:0042176550.020
organophosphate metabolic processGO:00196371950.020
dorsal closureGO:0007391790.019
mitotic g2 dna damage checkpointGO:0007095690.019
negative regulation of transcription dna templatedGO:00458922370.019
carboxylic acid metabolic processGO:0019752920.019
positive regulation of neurogenesisGO:0050769410.019
negative regulation of rna biosynthetic processGO:19026792400.019
negative regulation of response to stimulusGO:00485852580.019
cytoplasmic transportGO:00164821300.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
asymmetric cell divisionGO:0008356370.018
regulation of localizationGO:00328792750.018
meiosis iiGO:0007135230.018
cellular response to transforming growth factor beta stimulusGO:0071560180.018
regulation of protein modification processGO:00313991120.018
nuclear importGO:0051170510.018
oocyte differentiationGO:00099941450.018
Mouse
spermatogenesisGO:00072832000.018
embryonic development via the syncytial blastodermGO:00017001480.018
positive regulation of protein phosphorylationGO:0001934340.018
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.017
positive regulation of cellular component organizationGO:00511301560.017
positive regulation of transferase activityGO:0051347260.017
regulation of synapse assemblyGO:0051963940.017
response to organic cyclic compoundGO:0014070890.017
central nervous system formationGO:002155650.017
modification dependent macromolecule catabolic processGO:0043632790.017
cellular amino acid metabolic processGO:0006520610.017
regulation of cellular amine metabolic processGO:003323830.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
synaptic vesicle endocytosisGO:0048488280.016
posttranscriptional regulation of gene expressionGO:00106081450.016
establishment of protein localizationGO:00451841630.016
body morphogenesisGO:001017120.016
regulation of embryonic developmentGO:0045995680.016
regulation of neuron deathGO:1901214260.016
regulation of ubiquitin protein transferase activityGO:005143840.016
stem cell maintenanceGO:0019827670.016
positive regulation of protein transportGO:0051222370.016
protein import into nucleusGO:0006606510.015
positive regulation of protein metabolic processGO:00512471280.015
response to alcoholGO:0097305950.015
neuroblast proliferationGO:0007405740.015
regulation of nf kappab import into nucleusGO:004234510.015
female meiosis iGO:000714480.015
meiotic nuclear divisionGO:00071261510.015
Mouse
cellular response to organic substanceGO:00713101320.015
regulation of meiotic cell cycleGO:005144590.015
Mouse
negative regulation of oskar mrna translationGO:000731950.015
macromolecular complex assemblyGO:00650032560.015
regulation of cellular catabolic processGO:00313291570.015
regulation of protein phosphorylationGO:0001932640.015
regulation of sister chromatid cohesionGO:000706320.015
developmental growthGO:00485892800.015
unidimensional cell growthGO:0009826150.014
cell activationGO:000177590.014
positive regulation of transcription factor import into nucleusGO:0042993190.014
endomembrane system organizationGO:00102561190.014
positive regulation of signal transductionGO:00099672230.014
stress activated protein kinase signaling cascadeGO:0031098550.014
brain developmentGO:00074201200.014
dna damage checkpointGO:0000077780.014
positive regulation of mapk cascadeGO:0043410630.014
response to growth factorGO:0070848310.014
immune effector processGO:0002252980.014
regulation of cell proliferationGO:00421271630.014
negative regulation of epithelial cell proliferationGO:005068040.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.013
pronuclear migrationGO:003504640.013
positive regulation of immune responseGO:0050778630.013
positive regulation of catalytic activityGO:00430851180.013
regulation of cellular protein catabolic processGO:1903362440.013
positive regulation of programmed cell deathGO:0043068620.013
regulation of chromatin bindingGO:003556130.013
positive regulation of biosynthetic processGO:00098913160.013
regulation of histone deacetylationGO:003106320.013
microtubule polymerization or depolymerizationGO:0031109390.013
cell agingGO:000756920.013
central nervous system developmentGO:00074172010.013
regulation of protein localization to nucleusGO:1900180290.013
spindle checkpointGO:0031577110.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
negative regulation of signal transductionGO:00099682060.013
positive regulation of protein localization to nucleusGO:1900182210.012
lipid localizationGO:0010876540.012
epithelial cell migration open tracheal systemGO:0007427320.012
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.012
centrosome cycleGO:00070981370.012
protein importGO:0017038550.012
regulation of cellular component biogenesisGO:00440872010.012
aromatic compound catabolic processGO:00194391660.012
positive regulation of cellular catabolic processGO:0031331950.012
anatomical structure homeostasisGO:0060249970.012
extrinsic apoptotic signaling pathwayGO:009719110.012
innate immune responseGO:00450871440.012
positive regulation of jun kinase activityGO:004350740.012
developmental programmed cell deathGO:00106231380.012
maintenance of locationGO:0051235730.012
neuron projection guidanceGO:00974852410.012
stem cell proliferationGO:0072089880.012
regulation of response to stressGO:00801342000.012
oocyte microtubule cytoskeleton organizationGO:0016325350.012
regulation of hemocyte proliferationGO:0035206370.011
nuclear transcribed mrna catabolic processGO:0000956240.011
peptidyl threonine modificationGO:001821030.011
regulation of mrna 3 end processingGO:003144070.011
negative regulation of rna metabolic processGO:00512532510.011
oocyte constructionGO:00073081120.011
inorganic cation transmembrane transportGO:0098662610.011
mapk cascadeGO:00001651070.011
vesicle localizationGO:0051648550.011
positive regulation of dendrite developmentGO:190000690.011
regulation of intracellular signal transductionGO:19025312360.011
regulation of organ morphogenesisGO:2000027780.011
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.011
negative regulation of cell differentiationGO:00455961430.011
Mouse
negative regulation of signalingGO:00230572190.011
ras protein signal transductionGO:0007265880.011
rna localizationGO:00064031150.011
positive regulation of nervous system developmentGO:0051962690.011
regulation of purine nucleotide metabolic processGO:1900542620.011
positive regulation of protein kinase activityGO:0045860250.011
regulation of dna metabolic processGO:0051052340.011
small gtpase mediated signal transductionGO:0007264880.011
positive regulation of cellular amine metabolic processGO:003324000.011
glycerolipid metabolic processGO:0046486340.011
regulation of establishment of protein localizationGO:0070201610.011
sister chromatid cohesionGO:0007062180.011
head developmentGO:00603221350.011
development of primary sexual characteristicsGO:0045137500.011
defense responseGO:00069523000.010
response to radiationGO:00093141550.010
regulation of stress activated protein kinase signaling cascadeGO:0070302420.010
cellular response to growth factor stimulusGO:0071363300.010
positive regulation of mitotic cell cycleGO:0045931340.010
negative regulation of mitotic sister chromatid separationGO:2000816130.010
mrna processingGO:00063971040.010

wee disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.013