IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Cyp9b2 (Dmel_CG4486)

Cytochrome P450-9b2

(Aliases: P-450,CG4486,Dmel\CG4486,9b2,cyp9b2,BEST:GH08116,P450)

Entrez: 35635
FLYBASE: FBgn0015039
UniProtKB: Q9V4I1

Process Predictions
Disease Predictions

Cyp9b2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
toxin catabolic process	GO:0009407	1	0.638	Fly
insecticide metabolic process	GO:0017143	2	0.559	Fly
steroid catabolic process	GO:0006706	1	0.529	Human
xenobiotic catabolic process	GO:0042178	1	0.503	Fly
toxin metabolic process	GO:0009404	2	0.419	Fly
carboxylic acid metabolic process	GO:0019752	92	0.384	Fly
polyol biosynthetic process	GO:0046173	3	0.358	Human
secondary metabolite catabolic process	GO:0090487	1	0.321	Fly
insecticide catabolic process	GO:0046701	1	0.275	Fly
growth	GO:0040007	359	0.269	Fly
medium chain fatty acid metabolic process	GO:0051791	1	0.245	Fly
small molecule metabolic process	GO:0044281	305	0.241	Human Fly
response to organic substance	GO:0010033	284	0.238	Rat Fly
chaeta development	GO:0022416	97	0.233
organic hydroxy compound biosynthetic process	GO:1901617	21	0.216	Human Fly
secondary metabolic process	GO:0019748	75	0.216	Fly
oxoacid metabolic process	GO:0043436	103	0.209	Fly
lauric acid metabolic process	GO:0048252	1	0.201	Fly
sterol metabolic process	GO:0016125	12	0.181	Fly
anion homeostasis	GO:0055081	3	0.162	Rat
ketone biosynthetic process	GO:0042181	16	0.158	Fly
response to organic cyclic compound	GO:0014070	89	0.157	Rat Fly
developmental growth	GO:0048589	280	0.157	Fly
response to toxic substance	GO:0009636	22	0.148	Fly
steroid biosynthetic process	GO:0006694	16	0.145	Human Fly
response to mercury ion	GO:0046689	3	0.142	Fly
multi organism behavior	GO:0051705	175	0.125	Fly
response to inorganic substance	GO:0010035	44	0.123	Rat Fly
organonitrogen compound metabolic process	GO:1901564	318	0.121	Human
response to ddt	GO:0046680	5	0.098	Fly
hormone biosynthetic process	GO:0042446	20	0.098	Fly
head involution	GO:0008258	35	0.096
response to extracellular stimulus	GO:0009991	116	0.095	Rat
single organism biosynthetic process	GO:0044711	206	0.095	Human Fly
dorsal closure	GO:0007391	79	0.093
regulation of developmental growth	GO:0048638	174	0.093	Fly
response to endogenous stimulus	GO:0009719	119	0.093	Rat Fly
aggressive behavior	GO:0002118	63	0.092	Fly
response to temperature stimulus	GO:0009266	106	0.091	Fly
cellular hormone metabolic process	GO:0034754	23	0.087	Fly
response to alkaloid	GO:0043279	26	0.086	Fly
organic acid metabolic process	GO:0006082	103	0.084	Fly
fat soluble vitamin biosynthetic process	GO:0042362	1	0.082	Human
sulfur compound metabolic process	GO:0006790	59	0.079
positive regulation of gene expression	GO:0010628	290	0.077	Mouse
cellular response to chemical stimulus	GO:0070887	199	0.076	Fly
tergite morphogenesis	GO:0007490	1	0.076
vitamin metabolic process	GO:0006766	2	0.076	Human
hormone metabolic process	GO:0042445	33	0.071	Fly
lipid metabolic process	GO:0006629	121	0.071	Human Fly
cellular ketone metabolic process	GO:0042180	24	0.071	Fly
alcohol biosynthetic process	GO:0046165	14	0.070	Human Fly
single organism catabolic process	GO:0044712	228	0.067	Human Fly
organic hydroxy compound metabolic process	GO:1901615	83	0.066	Human Fly
response to lipopolysaccharide	GO:0032496	4	0.066
fat soluble vitamin metabolic process	GO:0006775	1	0.065	Human
cellular amino acid metabolic process	GO:0006520	61	0.064
organic cyclic compound catabolic process	GO:1901361	168	0.060	Human
chitin based cuticle development	GO:0040003	49	0.056
epithelial cell differentiation	GO:0030855	322	0.052
response to oxygen containing compound	GO:1901700	200	0.052
sterol biosynthetic process	GO:0016126	9	0.051	Fly
response to biotic stimulus	GO:0009607	294	0.051	Fly
cellular lipid metabolic process	GO:0044255	83	0.051	Human Fly
single organism behavior	GO:0044708	391	0.050	Fly
sensory perception of smell	GO:0007608	80	0.049	Fly
neurological system process	GO:0050877	358	0.048	Fly
morphogenesis of an epithelium	GO:0002009	276	0.047
positive regulation of multicellular organismal process	GO:0051240	143	0.047	Rat
cellular ion homeostasis	GO:0006873	39	0.047	Rat
morphogenesis of embryonic epithelium	GO:0016331	94	0.046
response to xenobiotic stimulus	GO:0009410	5	0.046	Zebrafish Fly
response to nutrient levels	GO:0031667	114	0.046	Rat
positive regulation of macromolecule metabolic process	GO:0010604	405	0.044	Mouse
alcohol metabolic process	GO:0006066	25	0.043	Human Fly
vitamin biosynthetic process	GO:0009110	1	0.043	Human
steroid metabolic process	GO:0008202	20	0.043	Human Fly
cellular catabolic process	GO:0044248	372	0.043	Human Fly
cellular nitrogen compound catabolic process	GO:0044270	165	0.043	Human
sensory perception	GO:0007600	196	0.042	Fly
ecdysteroid biosynthetic process	GO:0045456	15	0.041	Fly
aging	GO:0007568	143	0.041	Rat
embryo development ending in birth or egg hatching	GO:0009792	152	0.041
response to organonitrogen compound	GO:0010243	75	0.041	Fly
positive regulation of signal transduction	GO:0009967	223	0.040
positive regulation of response to stimulus	GO:0048584	323	0.039
tissue morphogenesis	GO:0048729	297	0.039
ovarian follicle cell development	GO:0030707	248	0.038
androgen metabolic process	GO:0008209	1	0.037
epithelial cell development	GO:0002064	274	0.037
negative regulation of signaling	GO:0023057	219	0.037
ecdysone metabolic process	GO:0008205	11	0.037	Fly
regulation of growth	GO:0040008	233	0.036	Fly
lipid biosynthetic process	GO:0008610	46	0.036	Human Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.033
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.032
intracellular signal transduction	GO:0035556	300	0.032
cellular homeostasis	GO:0019725	80	0.031	Rat
terpenoid metabolic process	GO:0006721	7	0.031	Human
regulation of hormone levels	GO:0010817	40	0.029	Fly
negative regulation of cell communication	GO:0010648	223	0.029
carbohydrate metabolic process	GO:0005975	82	0.029
central nervous system development	GO:0007417	201	0.029
response to hormone	GO:0009725	45	0.029	Rat
vesicle mediated transport	GO:0016192	381	0.028
response to nitrogen compound	GO:1901698	90	0.027	Fly
sensory perception of chemical stimulus	GO:0007606	116	0.027	Fly
ecdysone biosynthetic process	GO:0006697	9	0.027	Fly
regulation of intracellular signal transduction	GO:1902531	236	0.026
response to alcohol	GO:0097305	95	0.026
fatty acid metabolic process	GO:0006631	20	0.026	Fly
tube development	GO:0035295	244	0.026
cell division	GO:0051301	248	0.026
cell migration	GO:0016477	238	0.025
determination of adult lifespan	GO:0008340	137	0.025
aromatic compound catabolic process	GO:0019439	166	0.025
response to lipid	GO:0033993	38	0.025	Rat
acyl coa metabolic process	GO:0006637	3	0.025
catabolic process	GO:0009056	409	0.025	Human Fly
single organism cellular localization	GO:1902580	180	0.025
response to organophosphorus	GO:0046683	2	0.025	Fly
cellular protein modification process	GO:0006464	438	0.025
positive regulation of cell communication	GO:0010647	250	0.024
oxidation reduction process	GO:0055114	123	0.024	Human Mouse Rat Fly
estrogen metabolic process	GO:0008210	1	0.024
organonitrogen compound catabolic process	GO:1901565	128	0.024	Human
negative regulation of cellular metabolic process	GO:0031324	382	0.024
response to bacterium	GO:0009617	198	0.023	Fly
cell motility	GO:0048870	251	0.023
response to other organism	GO:0051707	293	0.023	Fly
ecdysteroid metabolic process	GO:0045455	19	0.023	Fly
regulation of multicellular organismal development	GO:2000026	414	0.023
negative regulation of response to stimulus	GO:0048585	258	0.022
small molecule biosynthetic process	GO:0044283	37	0.022	Human Fly
intracellular transport	GO:0046907	228	0.022
response to external biotic stimulus	GO:0043207	293	0.022	Fly
columnar cuboidal epithelial cell development	GO:0002066	249	0.022
regulation of localization	GO:0032879	275	0.022
organic substance transport	GO:0071702	257	0.022
response to abiotic stimulus	GO:0009628	341	0.022	Fly
positive regulation of signaling	GO:0023056	243	0.021
gland development	GO:0048732	191	0.021
organic substance catabolic process	GO:1901575	308	0.021	Human
heterocycle catabolic process	GO:0046700	166	0.021
cation transport	GO:0006812	110	0.021
monocarboxylic acid metabolic process	GO:0032787	29	0.021	Fly
endocytosis	GO:0006897	310	0.021
forebrain development	GO:0030900	2	0.021
regulation of cellular ketone metabolic process	GO:0010565	3	0.021
ion homeostasis	GO:0050801	55	0.021	Rat
negative regulation of signal transduction	GO:0009968	206	0.020
localization of cell	GO:0051674	257	0.020
transmembrane transport	GO:0055085	139	0.019
regulation of anatomical structure size	GO:0090066	163	0.019	Rat
isoprenoid metabolic process	GO:0006720	8	0.019	Human
cuticle development	GO:0042335	86	0.019
chemical homeostasis	GO:0048878	92	0.019	Rat
glycosyl compound metabolic process	GO:1901657	127	0.019
epithelium migration	GO:0090132	148	0.019
cellular modified amino acid metabolic process	GO:0006575	45	0.019
imaginal disc derived appendage development	GO:0048737	399	0.019
regulation of cell differentiation	GO:0045595	302	0.018
lipid catabolic process	GO:0016042	21	0.018	Human
regulation of molecular function	GO:0065009	217	0.018
wing disc morphogenesis	GO:0007472	344	0.018
embryonic morphogenesis	GO:0048598	206	0.018
regulation of multi organism process	GO:0043900	131	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.017
regulation of transport	GO:0051049	181	0.017
body morphogenesis	GO:0010171	2	0.017
multicellular organismal aging	GO:0010259	140	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
regulation of immune system process	GO:0002682	176	0.017
immune system process	GO:0002376	347	0.017
cellular chemical homeostasis	GO:0055082	40	0.017	Rat
defense response to gram negative bacterium	GO:0050829	94	0.017	Fly
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.017
nuclear division	GO:0000280	332	0.016
response to light stimulus	GO:0009416	124	0.016
cellular response to radiation	GO:0071478	52	0.016
ovarian follicle cell migration	GO:0007297	121	0.016
homeostatic process	GO:0042592	199	0.016	Rat
border follicle cell migration	GO:0007298	113	0.016
response to ethanol	GO:0045471	59	0.016
eye development	GO:0001654	323	0.016
chitin based embryonic cuticle biosynthetic process	GO:0008362	16	0.016
amine metabolic process	GO:0009308	12	0.016
protein modification process	GO:0036211	438	0.016
cell proliferation	GO:0008283	299	0.016
imaginal disc derived wing morphogenesis	GO:0007476	337	0.016
digestive system development	GO:0055123	149	0.016
epithelial cell migration	GO:0010631	148	0.016
regulation of protein metabolic process	GO:0051246	256	0.015
establishment of protein localization	GO:0045184	163	0.015
single organism carbohydrate metabolic process	GO:0044723	72	0.015
appendage development	GO:0048736	401	0.015
positive regulation of intracellular signal transduction	GO:1902533	116	0.015
protein transport	GO:0015031	155	0.015
protein localization	GO:0008104	284	0.015
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.015
regulation of immune effector process	GO:0002697	52	0.015
cellular response to endogenous stimulus	GO:0071495	80	0.015
response to cadmium ion	GO:0046686	9	0.015	Rat
response to copper ion	GO:0046688	4	0.014
organophosphate metabolic process	GO:0019637	195	0.014
single organism intracellular transport	GO:1902582	207	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
d amino acid transport	GO:0042940	1	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.014
regulation of catalytic activity	GO:0050790	185	0.014
cholesterol transport	GO:0030301	2	0.014
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.014
multi multicellular organism process	GO:0044706	123	0.014
phosphorylation	GO:0016310	294	0.014
post embryonic appendage morphogenesis	GO:0035120	385	0.014
cellular response to hormone stimulus	GO:0032870	44	0.014
inter male aggressive behavior	GO:0002121	60	0.013
cellular protein localization	GO:0034613	160	0.013
positive regulation of cell migration	GO:0030335	2	0.013
activation of innate immune response	GO:0002218	4	0.013
compound eye development	GO:0048749	307	0.013
regionalization	GO:0003002	416	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
cellular response to organic substance	GO:0071310	132	0.013
tissue migration	GO:0090130	155	0.013
phagocytosis	GO:0006909	215	0.013
intracellular protein transport	GO:0006886	104	0.013
macromolecular complex assembly	GO:0065003	256	0.013
protein complex assembly	GO:0006461	200	0.013
mitotic nuclear division	GO:0007067	213	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
reproductive behavior	GO:0019098	122	0.012
organelle fission	GO:0048285	340	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
midgut development	GO:0007494	23	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
cellular amine metabolic process	GO:0044106	12	0.012
camera type eye development	GO:0043010	4	0.012
acylglycerol biosynthetic process	GO:0046463	2	0.012
glutathione metabolic process	GO:0006749	37	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
immune response regulating signaling pathway	GO:0002764	2	0.012
telencephalon development	GO:0021537	2	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
appendage morphogenesis	GO:0035107	397	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
cellular macromolecule localization	GO:0070727	220	0.012
death	GO:0016265	284	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.011
cellular response to ethanol	GO:0071361	4	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
response to radiation	GO:0009314	155	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
imaginal disc pattern formation	GO:0007447	91	0.011
immune response activating signal transduction	GO:0002757	2	0.011
actin filament organization	GO:0007015	126	0.011
defense response to bacterium	GO:0042742	178	0.011	Fly
positive regulation of molecular function	GO:0044093	136	0.011
rna processing	GO:0006396	147	0.011
eye morphogenesis	GO:0048592	260	0.011
cell death	GO:0008219	279	0.011
protein complex biogenesis	GO:0070271	201	0.011
purine nucleotide metabolic process	GO:0006163	146	0.011
positive regulation of cellular component organization	GO:0051130	156	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011
phosphatidylethanolamine metabolic process	GO:0046337	1	0.011
connective tissue development	GO:0061448	3	0.011
positive regulation of transport	GO:0051050	92	0.011
positive regulation of cell motility	GO:2000147	3	0.010
cell adhesion	GO:0007155	136	0.010
mitotic cell cycle phase transition	GO:0044772	138	0.010
nitrogen compound transport	GO:0071705	85	0.010
organophosphate catabolic process	GO:0046434	112	0.010
defense response to other organism	GO:0098542	225	0.010	Fly

Cyp9b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
cardiovascular system disease	DOID:1287	0.288	Human
hypertension	DOID:10763	0.288	Human
artery disease	DOID:0050828	0.288	Human
disease of anatomical entity	DOID:7	0.288	Human
vascular disease	DOID:178	0.288	Human
essential hypertension	DOID:10825	0.158	Human
disease of metabolism	DOID:0014667	0.011
inherited metabolic disorder	DOID:655	0.011

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