IMP: Integrative Multi-species Prediction

Drosophila melanogaster

19 known processes

ImpL3 (Dmel_CG10160)

Ecdysone-inducible gene L3

(Aliases: Imp-L3,IMP-L3,Ldh,LDH,Dmel\CG10160,dmLDH,CG10160,Impl3)

FLYBASE: FBgn0001258
Entrez: 45880
UniProtKB: B5RJQ0
UniProtKB: Q95028

Process Predictions
Disease Predictions

ImpL3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
syncytium formation	GO:0006949	43	0.779
myoblast fusion	GO:0007520	43	0.743
muscle structure development	GO:0061061	224	0.452
syncytium formation by plasma membrane fusion	GO:0000768	43	0.348
carbohydrate metabolic process	GO:0005975	82	0.339
striated muscle cell differentiation	GO:0051146	90	0.258
single organism carbohydrate metabolic process	GO:0044723	72	0.239
organelle assembly	GO:0070925	198	0.231
muscle cell differentiation	GO:0042692	103	0.228
response to abiotic stimulus	GO:0009628	341	0.220	Rat
cellular carbohydrate metabolic process	GO:0044262	22	0.193
single organism biosynthetic process	GO:0044711	206	0.178
organophosphate metabolic process	GO:0019637	195	0.168	Rat
catabolic process	GO:0009056	409	0.158
single organism catabolic process	GO:0044712	228	0.133
response to heat	GO:0009408	63	0.128
actin cytoskeleton organization	GO:0030036	206	0.119
cellular component assembly involved in morphogenesis	GO:0010927	151	0.102
nucleobase containing small molecule metabolic process	GO:0055086	174	0.099	Rat
response to lithium ion	GO:0010226	1	0.099
aromatic compound catabolic process	GO:0019439	166	0.093
imaginal disc derived wing morphogenesis	GO:0007476	337	0.092
organophosphate biosynthetic process	GO:0090407	46	0.085
small molecule metabolic process	GO:0044281	305	0.084	Rat
actin filament based process	GO:0030029	220	0.083
response to extracellular stimulus	GO:0009991	116	0.075	Rat
gland development	GO:0048732	191	0.072
response to inorganic substance	GO:0010035	44	0.072	Rat
small molecule catabolic process	GO:0044282	21	0.068
myotube differentiation	GO:0014902	46	0.067
somatic muscle development	GO:0007525	66	0.067
purine nucleoside metabolic process	GO:0042278	127	0.065
cell adhesion	GO:0007155	136	0.064
intracellular signal transduction	GO:0035556	300	0.061
protein modification process	GO:0036211	438	0.060
organic substance catabolic process	GO:1901575	308	0.060
organophosphate catabolic process	GO:0046434	112	0.060
nucleotide metabolic process	GO:0009117	161	0.059	Rat
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.059
organonitrogen compound metabolic process	GO:1901564	318	0.058	Rat
response to glucose	GO:0009749	2	0.057	Rat
ovarian follicle cell development	GO:0030707	248	0.056
negative regulation of biosynthetic process	GO:0009890	277	0.056
negative regulation of response to stimulus	GO:0048585	258	0.055
determination of adult lifespan	GO:0008340	137	0.054
lipid metabolic process	GO:0006629	121	0.054
regulation of cell morphogenesis	GO:0022604	163	0.054
response to monosaccharide	GO:0034284	4	0.053	Rat
carboxylic acid metabolic process	GO:0019752	92	0.052	Rat
appendage morphogenesis	GO:0035107	397	0.052
wing disc morphogenesis	GO:0007472	344	0.051
cellular lipid metabolic process	GO:0044255	83	0.050
response to temperature stimulus	GO:0009266	106	0.047
response to nutrient levels	GO:0031667	114	0.047	Rat
protein complex biogenesis	GO:0070271	201	0.046
muscle attachment	GO:0016203	36	0.045
axonogenesis	GO:0007409	290	0.045
response to metal ion	GO:0010038	23	0.045
striated muscle myosin thick filament assembly	GO:0071688	3	0.044
striated muscle cell development	GO:0055002	50	0.043
ribonucleoside metabolic process	GO:0009119	127	0.043
regulation of intracellular signal transduction	GO:1902531	236	0.043
vesicle mediated transport	GO:0016192	381	0.042
macromolecular complex assembly	GO:0065003	256	0.042
cellular catabolic process	GO:0044248	372	0.042
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.041
ribose phosphate metabolic process	GO:0019693	145	0.041
heterocycle catabolic process	GO:0046700	166	0.040
regulation of cellular component size	GO:0032535	98	0.040
cellular response to peptide hormone stimulus	GO:0071375	28	0.039
purine containing compound metabolic process	GO:0072521	155	0.039
actin filament organization	GO:0007015	126	0.039
response to organic substance	GO:0010033	284	0.039	Rat
positive regulation of cell motility	GO:2000147	3	0.038
response to other organism	GO:0051707	293	0.038
endocytosis	GO:0006897	310	0.038
atp biosynthetic process	GO:0006754	2	0.038
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.038
multicellular organismal aging	GO:0010259	140	0.038
regionalization	GO:0003002	416	0.037
cellular protein modification process	GO:0006464	438	0.036
synapse assembly	GO:0007416	143	0.036
body morphogenesis	GO:0010171	2	0.036
response to starvation	GO:0042594	97	0.035
organic cyclic compound catabolic process	GO:1901361	168	0.035
glycerolipid metabolic process	GO:0046486	34	0.035
regulation of cellular component biogenesis	GO:0044087	201	0.034
chromosome organization	GO:0051276	360	0.034
phosphorylation	GO:0016310	294	0.034
nucleoside metabolic process	GO:0009116	127	0.034
response to peptide hormone	GO:0043434	29	0.033
positive regulation of transcription dna templated	GO:0045893	266	0.033
regulation of cell cycle	GO:0051726	291	0.033
regulation of myoblast fusion	GO:1901739	6	0.033
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.032
regulation of phosphate metabolic process	GO:0019220	210	0.032
response to organic cyclic compound	GO:0014070	89	0.032	Rat
response to lipopolysaccharide	GO:0032496	4	0.032
carbohydrate derivative metabolic process	GO:1901135	217	0.031
single organism intracellular transport	GO:1902582	207	0.031
post embryonic appendage morphogenesis	GO:0035120	385	0.031
chemotaxis	GO:0006935	249	0.031
columnar cuboidal epithelial cell development	GO:0002066	249	0.031
compound eye morphogenesis	GO:0001745	249	0.031
regulation of anatomical structure morphogenesis	GO:0022603	242	0.031
purine ribonucleotide catabolic process	GO:0009154	109	0.030
regulation of organelle organization	GO:0033043	196	0.030
regulation of cellular catabolic process	GO:0031329	157	0.030
developmental growth	GO:0048589	280	0.030
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.030
regulation of catalytic activity	GO:0050790	185	0.030
ras protein signal transduction	GO:0007265	88	0.029
response to nitrogen compound	GO:1901698	90	0.029	Rat
glycerophospholipid metabolic process	GO:0006650	23	0.029
salivary gland development	GO:0007431	162	0.028
regulation of phosphorylation	GO:0042325	147	0.028
positive regulation of cell migration	GO:0030335	2	0.028
carbohydrate derivative catabolic process	GO:1901136	118	0.028
ribonucleoside monophosphate biosynthetic process	GO:0009156	3	0.028
organonitrogen compound catabolic process	GO:1901565	128	0.028
nucleobase containing compound catabolic process	GO:0034655	165	0.028
protein localization	GO:0008104	284	0.028
cellular macromolecular complex assembly	GO:0034622	153	0.028
nucleoside phosphate metabolic process	GO:0006753	162	0.028	Rat
imaginal disc derived appendage development	GO:0048737	399	0.027
synapse organization	GO:0050808	196	0.027
regulation of phosphorus metabolic process	GO:0051174	210	0.027
negative regulation of gene expression	GO:0010629	387	0.027
regulation of cell cycle phase transition	GO:1901987	130	0.027
aging	GO:0007568	143	0.027
carbohydrate catabolic process	GO:0016052	7	0.027
protein complex assembly	GO:0006461	200	0.027
organelle fission	GO:0048285	340	0.027
nucleoside triphosphate catabolic process	GO:0009143	108	0.027
phagocytosis	GO:0006909	215	0.027
response to mercury ion	GO:0046689	3	0.027
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.026
positive regulation of biosynthetic process	GO:0009891	316	0.026
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.026
regulation of cellular protein metabolic process	GO:0032268	243	0.026
regulation of cell shape	GO:0008360	113	0.026
purine nucleotide metabolic process	GO:0006163	146	0.026
programmed cell death	GO:0012501	257	0.026	Rat
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.026
glycosyl compound catabolic process	GO:1901658	112	0.025
eye development	GO:0001654	323	0.025
purine ribonucleoside metabolic process	GO:0046128	127	0.025
regulation of response to stress	GO:0080134	200	0.025
compound eye development	GO:0048749	307	0.025
oxoacid metabolic process	GO:0043436	103	0.025	Rat
negative regulation of cellular metabolic process	GO:0031324	382	0.025
positive regulation of cellular component organization	GO:0051130	156	0.025
nucleoside triphosphate metabolic process	GO:0009141	120	0.024
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.024
nucleoside phosphate catabolic process	GO:1901292	110	0.024
eggshell formation	GO:0030703	105	0.024
mitotic nuclear division	GO:0007067	213	0.024
response to oxygen containing compound	GO:1901700	200	0.024	Rat
posttranscriptional regulation of gene expression	GO:0010608	145	0.024
gland morphogenesis	GO:0022612	145	0.024
purine containing compound catabolic process	GO:0072523	112	0.023
organonitrogen compound biosynthetic process	GO:1901566	117	0.023
regulation of catabolic process	GO:0009894	170	0.023
cellular response to organic substance	GO:0071310	132	0.023
cellular response to oxygen containing compound	GO:1901701	79	0.023
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.023
response to external biotic stimulus	GO:0043207	293	0.023
response to decreased oxygen levels	GO:0036293	58	0.023	Rat
mesenchymal cell differentiation	GO:0048762	1	0.023
atp metabolic process	GO:0046034	49	0.023
cellular response to peptide	GO:1901653	28	0.022
positive regulation of response to stimulus	GO:0048584	323	0.022
appendage development	GO:0048736	401	0.022
connective tissue development	GO:0061448	3	0.022
camera type eye development	GO:0043010	4	0.022
actomyosin structure organization	GO:0031032	56	0.022
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022
purine nucleotide catabolic process	GO:0006195	109	0.022
cellular macromolecule localization	GO:0070727	220	0.022
regulation of nucleoside metabolic process	GO:0009118	50	0.022
cell aging	GO:0007569	2	0.022
positive regulation of rna metabolic process	GO:0051254	271	0.022
chromosome segregation	GO:0007059	157	0.022
cellular protein complex assembly	GO:0043623	71	0.021
axon development	GO:0061564	297	0.021
organic substance transport	GO:0071702	257	0.021
neuron projection guidance	GO:0097485	241	0.021
cellular response to organonitrogen compound	GO:0071417	36	0.021
negative regulation of cell communication	GO:0010648	223	0.021
ribonucleoside catabolic process	GO:0042454	112	0.021
male gamete generation	GO:0048232	201	0.020
gtp metabolic process	GO:0046039	72	0.020
regulation of purine nucleotide metabolic process	GO:1900542	62	0.020
open tracheal system development	GO:0007424	204	0.020
cellular response to insulin stimulus	GO:0032869	28	0.020
glycosyl compound metabolic process	GO:1901657	127	0.020
myofibril assembly	GO:0030239	36	0.020
purine nucleotide biosynthetic process	GO:0006164	29	0.020
taxis	GO:0042330	304	0.020
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.020
cuticle development	GO:0042335	86	0.020
negative regulation of cell cycle	GO:0045786	116	0.020
purine ribonucleoside catabolic process	GO:0046130	112	0.020
small gtpase mediated signal transduction	GO:0007264	88	0.020
spermatogenesis	GO:0007283	200	0.020
apoptotic process	GO:0006915	159	0.019	Rat
regulation of cell projection organization	GO:0031344	92	0.019
ribose phosphate biosynthetic process	GO:0046390	28	0.019
carbohydrate derivative biosynthetic process	GO:1901137	85	0.019
regulation of ras protein signal transduction	GO:0046578	93	0.019
muscle system process	GO:0003012	21	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.019
cellular response to ethanol	GO:0071361	4	0.019
response to peptide	GO:1901652	29	0.019
wound healing	GO:0042060	75	0.019
centrosome organization	GO:0051297	163	0.019
regulation of multicellular organismal development	GO:2000026	414	0.019
microtubule organizing center organization	GO:0031023	168	0.019
regulation of developmental growth	GO:0048638	174	0.018
biological adhesion	GO:0022610	138	0.018
response to endogenous stimulus	GO:0009719	119	0.018	Rat
death	GO:0016265	284	0.018	Rat
cell cycle phase transition	GO:0044770	140	0.018
ribonucleotide catabolic process	GO:0009261	109	0.018
regulation of cell differentiation	GO:0045595	302	0.018
regulation of gene expression epigenetic	GO:0040029	128	0.018
negative regulation of gene expression epigenetic	GO:0045814	77	0.018
nucleoside catabolic process	GO:0009164	112	0.018
mitotic cell cycle phase transition	GO:0044772	138	0.018
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.018
regulation of protein metabolic process	GO:0051246	256	0.018
positive regulation of cellular biosynthetic process	GO:0031328	316	0.018
nuclear division	GO:0000280	332	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
immune response activating signal transduction	GO:0002757	2	0.017
respiratory system development	GO:0060541	213	0.017
cellular response to chemical stimulus	GO:0070887	199	0.017
response to light stimulus	GO:0009416	124	0.017
regulation of cell cycle process	GO:0010564	181	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.017
ribonucleoside triphosphate biosynthetic process	GO:0009201	2	0.017
response to gravity	GO:0009629	26	0.017
response to biotic stimulus	GO:0009607	294	0.017
negative regulation of signaling	GO:0023057	219	0.017
immune response regulating signaling pathway	GO:0002764	2	0.017
immune response	GO:0006955	246	0.017
ribonucleoside biosynthetic process	GO:0042455	3	0.017
purine nucleoside monophosphate biosynthetic process	GO:0009127	3	0.017
meiotic cell cycle	GO:0051321	171	0.017
positive regulation of rna biosynthetic process	GO:1902680	266	0.017
purine nucleoside biosynthetic process	GO:0042451	3	0.017
response to wounding	GO:0009611	94	0.017
regulation of cell adhesion	GO:0030155	27	0.016
mesenchymal cell development	GO:0014031	1	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
purine ribonucleotide biosynthetic process	GO:0009152	28	0.016
response to insulin	GO:0032868	29	0.016
rho protein signal transduction	GO:0007266	14	0.016
regulation of epithelial cell proliferation	GO:0050678	4	0.016
cellular nitrogen compound catabolic process	GO:0044270	165	0.016
morphogenesis of an epithelium	GO:0002009	276	0.016
wing disc pattern formation	GO:0035222	66	0.016
gene silencing	GO:0016458	138	0.016
negative regulation of signal transduction	GO:0009968	206	0.016
extracellular structure organization	GO:0043062	46	0.016
cellular response to nitrogen compound	GO:1901699	51	0.016
chorion containing eggshell formation	GO:0007304	105	0.016
positive regulation of nucleoside metabolic process	GO:0045979	47	0.015
macromolecule catabolic process	GO:0009057	161	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
organic acid metabolic process	GO:0006082	103	0.015	Rat
transcription from rna polymerase ii promoter	GO:0006366	368	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
regulation of cell substrate adhesion	GO:0010810	2	0.015
tube development	GO:0035295	244	0.015
regulation of cytoskeleton organization	GO:0051493	89	0.015
kidney development	GO:0001822	3	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
estrogen metabolic process	GO:0008210	1	0.015
growth	GO:0040007	359	0.015
heart development	GO:0007507	82	0.015
ribonucleotide metabolic process	GO:0009259	145	0.015
protein transport	GO:0015031	155	0.015
epithelial cell development	GO:0002064	274	0.015
forebrain development	GO:0030900	2	0.015
nucleotide catabolic process	GO:0009166	109	0.014
signal transduction by phosphorylation	GO:0023014	107	0.014
cell motility	GO:0048870	251	0.014
response to organophosphorus	GO:0046683	2	0.014	Rat
regulation of mapk cascade	GO:0043408	92	0.014
guanosine containing compound catabolic process	GO:1901069	74	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
response to bacterium	GO:0009617	198	0.014
nucleoside phosphate biosynthetic process	GO:1901293	34	0.014
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.014
establishment or maintenance of cell polarity	GO:0007163	167	0.014
positive regulation of cellular component biogenesis	GO:0044089	80	0.014
regulation of nucleotide metabolic process	GO:0006140	62	0.014
regulation of immune system process	GO:0002682	176	0.014
regulation of anatomical structure size	GO:0090066	163	0.014
homeostatic process	GO:0042592	199	0.014
glycosyl compound biosynthetic process	GO:1901659	3	0.014
purine nucleoside catabolic process	GO:0006152	112	0.014
positive regulation of gene expression	GO:0010628	290	0.014
rna processing	GO:0006396	147	0.014
pyridine containing compound metabolic process	GO:0072524	3	0.013	Rat
positive regulation of catabolic process	GO:0009896	105	0.013
organic hydroxy compound catabolic process	GO:1901616	4	0.013
tube morphogenesis	GO:0035239	191	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.013
regeneration	GO:0031099	16	0.013
intracellular transport	GO:0046907	228	0.013
regulation of cell development	GO:0060284	215	0.013
single organism cell adhesion	GO:0098602	47	0.013
tissue morphogenesis	GO:0048729	297	0.013
purine ribonucleoside biosynthetic process	GO:0046129	3	0.013
negative regulation of rna metabolic process	GO:0051253	251	0.013
morphogenesis of a branching structure	GO:0001763	45	0.013
morphogenesis of a branching epithelium	GO:0061138	45	0.013
wnt signaling pathway	GO:0016055	98	0.013
larval development	GO:0002164	104	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.013
positive regulation of molecular function	GO:0044093	136	0.013
lateral inhibition	GO:0046331	206	0.013
hormone catabolic process	GO:0042447	3	0.013
positive regulation of nucleotide metabolic process	GO:0045981	55	0.013
ameboidal type cell migration	GO:0001667	151	0.013
gtp catabolic process	GO:0006184	72	0.013
epithelial tube morphogenesis	GO:0060562	88	0.013
muscle cell development	GO:0055001	50	0.013
positive regulation of multicellular organismal process	GO:0051240	143	0.013
proteolysis	GO:0006508	192	0.013
kidney morphogenesis	GO:0060993	3	0.013
sister chromatid segregation	GO:0000819	92	0.013
nucleotide biosynthetic process	GO:0009165	34	0.013
regulation of myotube differentiation	GO:0010830	6	0.013
imaginal disc pattern formation	GO:0007447	91	0.013
cell proliferation	GO:0008283	299	0.013
myotube cell development	GO:0014904	3	0.012
chromatin organization	GO:0006325	207	0.012
salivary gland histolysis	GO:0035070	88	0.012
regulation of localization	GO:0032879	275	0.012
response to oxidative stress	GO:0006979	86	0.012	Rat
response to oxygen levels	GO:0070482	59	0.012	Rat
cytoplasmic transport	GO:0016482	130	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
autophagic cell death	GO:0048102	83	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
mapk cascade	GO:0000165	107	0.012
cellular response to hormone stimulus	GO:0032870	44	0.012
branching involved in open tracheal system development	GO:0060446	45	0.012
developmental maturation	GO:0021700	172	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
antimicrobial humoral response	GO:0019730	99	0.012
positive regulation of immune response	GO:0050778	63	0.012
axon guidance	GO:0007411	233	0.012
regulation of cellular component movement	GO:0051270	42	0.012
cell cycle checkpoint	GO:0000075	95	0.012
intracellular protein transmembrane transport	GO:0065002	4	0.012
positive regulation of cellular catabolic process	GO:0031331	95	0.012
purine containing compound biosynthetic process	GO:0072522	30	0.012
cell junction organization	GO:0034330	57	0.012
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.012
negative regulation of transcription dna templated	GO:0045892	237	0.012
glycolytic process	GO:0006096	6	0.012
chaeta development	GO:0022416	97	0.012
substrate adhesion dependent cell spreading	GO:0034446	2	0.012
translation	GO:0006412	69	0.012
positive regulation of developmental process	GO:0051094	143	0.012
meiotic nuclear division	GO:0007126	151	0.012
positive regulation of hydrolase activity	GO:0051345	78	0.012
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
defense response	GO:0006952	300	0.011
regulation of actin cytoskeleton organization	GO:0032956	42	0.011
dorsal appendage formation	GO:0046843	47	0.011
nucleoside biosynthetic process	GO:0009163	3	0.011
phospholipid metabolic process	GO:0006644	23	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
regulation of gtpase activity	GO:0043087	44	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
lipid storage	GO:0019915	38	0.011
negative regulation of mitotic cell cycle	GO:0045930	109	0.011
positive regulation of developmental growth	GO:0048639	62	0.011
single organismal cell cell adhesion	GO:0016337	45	0.011
retina development in camera type eye	GO:0060041	4	0.011
cell cycle arrest	GO:0007050	4	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
negative regulation of developmental process	GO:0051093	201	0.011
regulation of notch signaling pathway	GO:0008593	100	0.011
nephron epithelium development	GO:0072009	3	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.011
stem cell development	GO:0048864	79	0.011
regulation of response to external stimulus	GO:0032101	115	0.011
defense response to other organism	GO:0098542	225	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
telencephalon development	GO:0021537	2	0.011
lipid biosynthetic process	GO:0008610	46	0.011
regulation of actin filament length	GO:0030832	27	0.011
transmembrane transport	GO:0055085	139	0.011
benzene containing compound metabolic process	GO:0042537	3	0.011
leg disc development	GO:0035218	92	0.011
negative regulation of cell cycle process	GO:0010948	109	0.011
integrin mediated signaling pathway	GO:0007229	3	0.011
protein phosphorylation	GO:0006468	169	0.011
regulation of protein complex assembly	GO:0043254	42	0.011
stress activated mapk cascade	GO:0051403	52	0.011
regulation of molecular function	GO:0065009	217	0.011
lamellipodium assembly	GO:0030032	21	0.011
alcohol catabolic process	GO:0046164	4	0.010
cellular amine metabolic process	GO:0044106	12	0.010
actin filament polymerization	GO:0030041	27	0.010
regulation of neuron differentiation	GO:0045664	103	0.010
guanosine containing compound metabolic process	GO:1901068	74	0.010
positive regulation of phosphorylation	GO:0042327	87	0.010
protein transmembrane transport	GO:0071806	4	0.010
sensory perception of chemical stimulus	GO:0007606	116	0.010
positive regulation of immune system process	GO:0002684	68	0.010
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.010
positive regulation of cell communication	GO:0010647	250	0.010
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.010
intracellular protein transport	GO:0006886	104	0.010
positive regulation of mapk cascade	GO:0043410	63	0.010
notch signaling pathway	GO:0007219	120	0.010
ribonucleotide biosynthetic process	GO:0009260	28	0.010
chromatin silencing	GO:0006342	76	0.010
regulation of nucleotide catabolic process	GO:0030811	48	0.010
regulation of cell matrix adhesion	GO:0001952	1	0.010
cell projection assembly	GO:0030031	94	0.010
innate immune response	GO:0045087	144	0.010
nephron tubule development	GO:0072080	3	0.010
positive regulation of ras gtpase activity	GO:0032320	36	0.010
protein polymerization	GO:0051258	42	0.010
embryo development ending in birth or egg hatching	GO:0009792	152	0.010

ImpL3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.043
musculoskeletal system disease	DOID:17	0.020
urinary system disease	DOID:18	0.018
nervous system disease	DOID:863	0.018
disease of cellular proliferation	DOID:14566	0.012
connective tissue disease	DOID:65	0.010

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