Drosophila melanogaster

29 known processes

tmod (Dmel_CG1539)

tropomodulin

(Aliases: E42,CG1539,CT41421,CG15540,1309/10,l(3)00848,Tmod,CT3919,spdo,l(3)S130910,CG11493,Dmel\CG1539)

tmod biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myofibril assemblyGO:0030239360.962
Mouse Worm
actomyosin structure organizationGO:0031032560.912
Mouse Worm
sarcomere organizationGO:0045214260.858
Worm
cellular component assembly involved in morphogenesisGO:00109271510.837
Mouse Worm
organelle assemblyGO:00709251980.824
Mouse Worm
muscle cell differentiationGO:00426921030.796
Mouse Worm
actin filament based processGO:00300292200.790
Mouse Worm
striated muscle cell developmentGO:0055002500.765
Mouse Worm
muscle structure developmentGO:00610612240.763
Mouse Worm
adult somatic muscle developmentGO:0007527140.717
striated muscle cell differentiationGO:0051146900.640
Mouse Worm
actin cytoskeleton organizationGO:00300362060.382
Mouse Worm
striated muscle myosin thick filament assemblyGO:007168830.301
regulation of localizationGO:00328792750.258
regulation of cellular catabolic processGO:00313291570.168
establishment of localization in cellGO:00516494020.164
positive regulation of cellular component organizationGO:00511301560.163
organonitrogen compound metabolic processGO:19015643180.143
actin filament organizationGO:00070151260.141
Worm
tube morphogenesisGO:00352391910.131
somatic muscle developmentGO:0007525660.116
cellular macromolecule localizationGO:00707272200.114
positive regulation of nucleotide catabolic processGO:0030813460.113
single organism cellular localizationGO:19025801800.111
protein transportGO:00150311550.109
regionalizationGO:00030024160.107
protein complex biogenesisGO:00702712010.104
Worm
regulation of cell developmentGO:00602842150.103
protein complex assemblyGO:00064612000.103
Worm
developmental maturationGO:00217001720.101
regulation of defense responseGO:00313471020.100
positive regulation of catabolic processGO:00098961050.100
positive regulation of cellular catabolic processGO:0031331950.099
positive regulation of nucleobase containing compound metabolic processGO:00459353320.099
cellular catabolic processGO:00442483720.086
sensory organ morphogenesisGO:00905962600.083
regulation of intracellular signal transductionGO:19025312360.082
regulation of catabolic processGO:00098941700.082
muscle cell developmentGO:0055001500.081
Mouse Worm
cellular macromolecular complex assemblyGO:00346221530.081
Worm
catabolic processGO:00090564090.081
Worm
ribonucleoside triphosphate metabolic processGO:00091991190.078
positive regulation of nitrogen compound metabolic processGO:00511733540.077
regulation of actin cytoskeleton organizationGO:0032956420.077
Worm
cell divisionGO:00513012480.077
negative regulation of gene expressionGO:00106293870.076
positive regulation of nucleoside metabolic processGO:0045979470.076
programmed cell deathGO:00125012570.075
embryonic pattern specificationGO:00098801740.075
multicellular organismal agingGO:00102591400.073
positive regulation of gtpase activityGO:0043547430.073
positive regulation of transcription dna templatedGO:00458932660.073
endocytosisGO:00068973100.072
molting cycleGO:0042303560.071
macromolecular complex assemblyGO:00650032560.071
Worm
respiratory system developmentGO:00605412130.070
organelle fissionGO:00482853400.067
heterocycle catabolic processGO:00467001660.066
embryo development ending in birth or egg hatchingGO:00097921520.065
Worm
nucleoside triphosphate catabolic processGO:00091431080.065
regulation of cell differentiationGO:00455953020.065
regulation of organelle organizationGO:00330431960.064
Worm
aromatic compound catabolic processGO:00194391660.063
regulation of anatomical structure morphogenesisGO:00226032420.062
striated muscle tissue developmentGO:0014706270.062
purine containing compound catabolic processGO:00725231120.062
digestive tract morphogenesisGO:00485461270.061
positive regulation of purine nucleotide catabolic processGO:0033123460.059
nucleobase containing small molecule metabolic processGO:00550861740.059
intracellular protein transportGO:00068861040.059
immune system processGO:00023763470.058
anatomical structure homeostasisGO:0060249970.057
mesoderm developmentGO:0007498780.056
regulation of gtp catabolic processGO:0033124440.054
blastoderm segmentationGO:00073501590.054
regulation of cellular localizationGO:00603411360.054
protein localizationGO:00081042840.052
purine nucleoside triphosphate metabolic processGO:00091441190.052
cellular homeostasisGO:0019725800.052
proteolysisGO:00065081920.052
agingGO:00075681430.050
embryonic morphogenesisGO:00485982060.050
positive regulation of multicellular organismal processGO:00512401430.049
organic substance catabolic processGO:19015753080.049
Worm
regulation of cell morphogenesisGO:00226041630.049
secretionGO:00469031090.049
organic cyclic compound catabolic processGO:19013611680.049
establishment of protein localizationGO:00451841630.048
eye developmentGO:00016543230.047
positive regulation of phosphate metabolic processGO:00459371390.046
hair cell differentiationGO:0035315470.046
body morphogenesisGO:001017120.045
tube developmentGO:00352952440.045
compound eye morphogenesisGO:00017452490.045
small molecule metabolic processGO:00442813050.045
positive regulation of hydrolase activityGO:0051345780.044
regulation of cellular component biogenesisGO:00440872010.044
Worm
cellular protein complex assemblyGO:0043623710.044
Worm
myosin filament organizationGO:003103350.044
positive regulation of macromolecule metabolic processGO:00106044050.043
regulation of multicellular organismal developmentGO:20000264140.042
regulation of actin filament lengthGO:0030832270.042
Worm
anterior posterior pattern specificationGO:00099521360.042
positive regulation of nucleotide metabolic processGO:0045981550.042
nucleobase containing compound catabolic processGO:00346551650.042
cell maturationGO:00484691440.041
negative regulation of actin filament depolymerizationGO:003083520.041
Worm
negative regulation of response to stimulusGO:00485852580.041
epidermis developmentGO:0008544650.040
nucleoside catabolic processGO:00091641120.040
regulation of actin filament depolymerizationGO:003083430.039
Worm
regulation of hydrolase activityGO:0051336970.039
positive regulation of gtp catabolic processGO:0033126430.039
regulation of vesicle mediated transportGO:0060627590.039
nucleotide catabolic processGO:00091661090.039
positive regulation of cell developmentGO:0010720610.038
mitotic cytokinesisGO:0000281500.038
neuron recognitionGO:00080381010.037
actin filament bundle assemblyGO:0051017260.037
regulation of protein transportGO:0051223570.037
vesicle mediated transportGO:00161923810.037
regulation of phosphorus metabolic processGO:00511742100.037
macromolecule catabolic processGO:00090571610.036
Worm
regulation of molecular functionGO:00650092170.036
positive regulation of rna metabolic processGO:00512542710.036
regulation of cell maturationGO:1903429270.036
positive regulation of nucleic acid templated transcriptionGO:19035082660.036
cytoplasmic transportGO:00164821300.036
purine nucleotide catabolic processGO:00061951090.036
positive regulation of macromolecule biosynthetic processGO:00105572830.036
establishment of nucleus localizationGO:0040023260.035
cognitionGO:00508901410.035
cytokinesisGO:0000910900.035
locomotory behaviorGO:00076261760.035
Mouse
nucleotide metabolic processGO:00091171610.035
negative regulation of organelle organizationGO:0010639560.034
Worm
nucleoside phosphate metabolic processGO:00067531620.034
regulation of rho protein signal transductionGO:0035023200.034
purine ribonucleoside metabolic processGO:00461281270.034
cellular protein localizationGO:00346131600.033
defense response to other organismGO:00985422250.033
cellular protein complex disassemblyGO:0043624350.033
Worm
single organism intracellular transportGO:19025822070.033
protein modification processGO:00362114380.032
retina development in camera type eyeGO:006004140.032
regulation of nucleotide catabolic processGO:0030811480.032
intracellular signal transductionGO:00355563000.032
regulation of immune responseGO:00507761180.032
regulation of neuron projection developmentGO:0010975690.032
imaginal disc derived wing hair organizationGO:0035317450.031
positive regulation of purine nucleotide metabolic processGO:1900544550.031
phagocytosisGO:00069092150.031
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.031
regulation of transportGO:00510491810.031
axis specificationGO:00097981670.031
carbohydrate derivative metabolic processGO:19011352170.031
muscle tissue morphogenesisGO:006041520.030
mitotic sister chromatid segregationGO:0000070870.030
regulation of programmed cell deathGO:00430671520.030
defense response to bacteriumGO:00427421780.030
protein depolymerizationGO:0051261310.030
Worm
skeletal myofibril assemblyGO:001486660.030
oocyte developmentGO:00485991240.029
cell projection assemblyGO:0030031940.029
purine ribonucleoside catabolic processGO:00461301120.029
stem cell differentiationGO:00488631170.029
ribonucleoside catabolic processGO:00424541120.029
spindle organizationGO:00070512530.029
cytoskeleton dependent cytokinesisGO:0061640810.029
purine ribonucleoside triphosphate metabolic processGO:00092051190.028
glycosyl compound catabolic processGO:19016581120.028
regulation of ras gtpase activityGO:0032318380.028
regulation of protein depolymerizationGO:1901879270.028
Worm
actin filament depolymerizationGO:003004250.028
Worm
epithelial tube morphogenesisGO:0060562880.028
spiracle morphogenesis open tracheal systemGO:0035277220.028
peptide metabolic processGO:0006518800.027
metal ion transportGO:0030001740.027
positive regulation of phosphorus metabolic processGO:00105621390.027
germarium derived female germ line cyst formationGO:0030727420.027
actin filament bundle organizationGO:0061572280.027
positive regulation of actin filament polymerizationGO:0030838110.027
purine ribonucleotide catabolic processGO:00091541090.026
regulation of protein polymerizationGO:0032271280.026
Worm
heart developmentGO:0007507820.026
cell deathGO:00082192790.026
regulation of cytoskeleton organizationGO:0051493890.026
Worm
regulation of gtpase activityGO:0043087440.026
ribonucleotide catabolic processGO:00092611090.026
morphogenesis of an epitheliumGO:00020092760.026
cell recognitionGO:00080371020.025
purine ribonucleoside triphosphate catabolic processGO:00092071080.025
cellularizationGO:0007349900.025
protein catabolic processGO:00301631010.025
Worm
gastrulation involving germ band extensionGO:0010004360.025
regulation of anatomical structure sizeGO:00900661630.025
Worm
regulation of dendrite developmentGO:0050773370.024
regulation of multi organism processGO:00439001310.024
sodium ion transportGO:0006814220.024
positive regulation of biosynthetic processGO:00098913160.024
positive regulation of molecular functionGO:00440931360.024
cellular amino acid metabolic processGO:0006520610.024
regulation of endocytosisGO:0030100370.024
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
non sensory hair organizationGO:0035316470.023
cell adhesionGO:00071551360.023
oocyte differentiationGO:00099941450.023
ribonucleoside metabolic processGO:00091191270.023
muscle organ developmentGO:00075171270.023
kidney developmentGO:000182230.022
regulation of cell substrate adhesionGO:001081020.022
regulation of apoptotic processGO:00429811300.022
negative regulation of cytoskeleton organizationGO:0051494300.022
Worm
regulation of catalytic activityGO:00507901850.022
regulation of cell cycleGO:00517262910.022
convergent extensionGO:006002620.022
embryonic development via the syncytial blastodermGO:00017001480.022
myosin filament assemblyGO:003103450.022
chromosome condensationGO:0030261410.022
positive regulation of signal transductionGO:00099672230.021
nucleoside triphosphate metabolic processGO:00091411200.021
glycosyl compound metabolic processGO:19016571270.021
ion transportGO:00068111450.021
nuclear divisionGO:00002803320.021
regulation of dendrite morphogenesisGO:0048814280.021
ribonucleoside triphosphate catabolic processGO:00092031080.021
positive regulation of cellular component biogenesisGO:0044089800.020
compound eye developmentGO:00487493070.020
response to woundingGO:0009611940.020
biological adhesionGO:00226101380.020
response to other organismGO:00517072930.020
positive regulation of response to stimulusGO:00485843230.020
regulation of cell projection organizationGO:0031344920.020
gastrulation with mouth forming firstGO:0001703360.020
positive regulation of developmental processGO:00510941430.020
post embryonic appendage morphogenesisGO:00351203850.020
guanosine containing compound metabolic processGO:1901068740.020
cellular protein modification processGO:00064644380.020
epidermal cell differentiationGO:0009913510.020
negative regulation of protein complex disassemblyGO:0043242230.019
Worm
intracellular transportGO:00469072280.019
intercellular bridge organizationGO:0043063140.019
oligosaccharide biosynthetic processGO:0009312100.019
organophosphate catabolic processGO:00464341120.019
camera type eye developmentGO:004301040.019
nucleoside phosphate catabolic processGO:19012921100.019
cellular component disassemblyGO:0022411460.019
Worm
regulation of cell deathGO:00109411730.019
carbohydrate derivative catabolic processGO:19011361180.019
dendrite morphogenesisGO:00488131990.019
gtp catabolic processGO:0006184720.019
germarium derived egg chamber formationGO:00072931010.018
tissue morphogenesisGO:00487292970.018
homeostatic processGO:00425921990.018
eye morphogenesisGO:00485922600.018
apoptotic processGO:00069151590.018
cytoplasmic transport nurse cell to oocyteGO:0007303120.018
gtp metabolic processGO:0046039720.018
regulation of cell shapeGO:00083601130.018
neuron remodelingGO:0016322290.018
guanosine containing compound catabolic processGO:1901069740.018
germ line cyst formationGO:0048134440.018
determination of adult lifespanGO:00083401370.018
regulation of proteolysisGO:0030162870.018
skeletal muscle myosin thick filament assemblyGO:003024130.018
regulation of immune system processGO:00026821760.018
response to external biotic stimulusGO:00432072930.018
single organism catabolic processGO:00447122280.017
regulation of phosphate metabolic processGO:00192202100.017
rhabdomere developmentGO:0042052380.017
regulation of tube length open tracheal systemGO:0035159240.017
chemical homeostasisGO:0048878920.017
digestive system developmentGO:00551231490.017
oocyte constructionGO:00073081120.017
negative regulation of cellular metabolic processGO:00313243820.017
nucleoside metabolic processGO:00091161270.016
regulation of cell growthGO:0001558430.016
ras protein signal transductionGO:0007265880.016
positive regulation of protein polymerizationGO:0032273140.016
epithelial cell differentiationGO:00308553220.016
organophosphate metabolic processGO:00196371950.016
positive regulation of catalytic activityGO:00430851180.016
regulation of protein localizationGO:0032880760.016
extracellular structure organizationGO:0043062460.016
cell cycle arrestGO:000705040.016
cell proliferationGO:00082832990.016
dephosphorylationGO:0016311510.016
regulation of actin filament polymerizationGO:0030833250.016
Worm
neuron projection guidanceGO:00974852410.015
ribose phosphate metabolic processGO:00196931450.015
wound healingGO:0042060750.015
actin polymerization or depolymerizationGO:0008154310.015
Worm
positive regulation of signalingGO:00230562430.015
regulation of neuron differentiationGO:00456641030.015
imaginal disc growthGO:0007446370.015
negative regulation of cell deathGO:0060548810.015
regulation of purine nucleotide catabolic processGO:0033121480.015
glycoprotein biosynthetic processGO:0009101410.015
purine nucleotide metabolic processGO:00061631460.015
embryonic axis specificationGO:00005781070.014
positive regulation of ras gtpase activityGO:0032320360.014
organonitrogen compound catabolic processGO:19015651280.014
mesenchymal cell differentiationGO:004876210.014
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.014
protein targetingGO:0006605640.014
nuclear migrationGO:0007097200.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
regulation of oocyte developmentGO:0060281270.014
oocyte fate determinationGO:0030716270.014
negative regulation of protein depolymerizationGO:1901880230.014
Worm
gene silencingGO:00164581380.014
morphogenesis of a branching epitheliumGO:0061138450.013
skin developmentGO:0043588650.013
regulation of cytoplasmic transportGO:1903649470.013
tissue deathGO:00162711020.013
defense responseGO:00069523000.013
intracellular protein transmembrane transportGO:006500240.013
positive regulation of cellular biosynthetic processGO:00313283160.013
nicotinamide nucleotide metabolic processGO:004649620.013
response to biotic stimulusGO:00096072940.013
lamellipodium organizationGO:0097581210.013
nucleus localizationGO:0051647340.013
axon developmentGO:00615642970.013
camera type eye morphogenesisGO:004859320.013
negative regulation of catalytic activityGO:0043086420.013
morphogenesis of embryonic epitheliumGO:0016331940.012
wnt signaling pathwayGO:0016055980.012
muscle thin filament assemblyGO:007168950.012
Worm
intracellular mrna localization involved in pattern specification processGO:0060810560.012
protein maturationGO:0051604710.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
positive regulation of cell deathGO:0010942690.012
cellular amide metabolic processGO:0043603800.012
regulation of cellular amine metabolic processGO:003323830.012
positive regulation of cytoskeleton organizationGO:0051495210.012
protein importGO:0017038550.012
segmentationGO:00352822070.012
anterior posterior axis specification embryoGO:00085951030.012
tripartite regional subdivisionGO:00073511030.012
mitotic nuclear divisionGO:00070672130.012
branching involved in open tracheal system developmentGO:0060446450.012
olfactory behaviorGO:0042048970.012
female germ line cyst formationGO:0048135420.011
o glycan processingGO:001626630.011
negative regulation of programmed cell deathGO:0043069720.011
cytoskeleton dependent intracellular transportGO:0030705440.011
response to bacteriumGO:00096171980.011
positive regulation of nervous system developmentGO:0051962690.011
actin mediated cell contractionGO:0070252210.011
microtubule polymerization or depolymerizationGO:0031109390.011
maintenance of locationGO:0051235730.011
regulation of establishment of protein localizationGO:0070201610.011
positive regulation of rna biosynthetic processGO:19026802660.011
actin cytoskeleton reorganizationGO:0031532220.011
cell motilityGO:00488702510.011
cellular macromolecule catabolic processGO:00442651360.011
transcription from rna polymerase ii promoterGO:00063663680.011
dna metabolic processGO:00062592270.011
regulation of innate immune responseGO:0045088710.011
negative regulation of cellular component organizationGO:00511291080.011
Worm
purine nucleoside metabolic processGO:00422781270.011
developmental programmed cell deathGO:00106231380.010
actin filament based movementGO:0030048260.010
meiotic nuclear divisionGO:00071261510.010
cellular chemical homeostasisGO:0055082400.010
production of small rna involved in gene silencing by rnaGO:0070918150.010
regulation of reproductive processGO:2000241540.010
salivary gland developmentGO:00074311620.010
mrna processingGO:00063971040.010
negative regulation of apoptotic processGO:0043066630.010
peptide hormone processingGO:001648620.010
organic substance transportGO:00717022570.010
cellular nitrogen compound catabolic processGO:00442701650.010

tmod disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
cardiovascular system diseaseDOID:128700.016
nervous system diseaseDOID:86300.016
muscular diseaseDOID:008000000.015
musculoskeletal system diseaseDOID:1700.015
connective tissue diseaseDOID:6500.014
disease of cellular proliferationDOID:1456600.014
muscle tissue diseaseDOID:6600.013
intrinsic cardiomyopathyDOID:006003600.013
dilated cardiomyopathyDOID:1293000.013
cardiomyopathyDOID:005070000.013
heart diseaseDOID:11400.013
myopathyDOID:42300.013
organ system cancerDOID:005068600.011
cancerDOID:16200.011
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011