Drosophila melanogaster

14 known processes

l(3)mbn (Dmel_CG12755)

lethal (3) malignant blood neoplasm

(Aliases: MBN,l(3)malignant blood neoplasm1,Dmel\CG12755,l(3)mbn1,l(3)mbn-1,CG12755)

l(3)mbn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023763470.805
immune responseGO:00069552460.764
innate immune responseGO:00450871440.498
defense responseGO:00069523000.430
defense response to gram positive bacteriumGO:0050830410.429
response to biotic stimulusGO:00096072940.294
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.275
response to bacteriumGO:00096171980.246
positive regulation of production of molecular mediator of immune responseGO:0002702280.218
response to other organismGO:00517072930.201
peptide metabolic processGO:0006518800.194
immune effector processGO:0002252980.175
defense response to bacteriumGO:00427421780.143
humoral immune responseGO:00069591170.135
negative regulation of developmental processGO:00510932010.135
phenol containing compound metabolic processGO:0018958570.133
melanization defense responseGO:0035006450.127
encapsulation of foreign targetGO:0035010380.125
immune response regulating signaling pathwayGO:000276420.121
positive regulation of humoral immune responseGO:0002922280.114
pattern recognition receptor signaling pathwayGO:000222120.112
antibacterial humoral responseGO:0019731440.112
toll signaling pathwayGO:0008063250.103
production of molecular mediator of immune responseGO:0002440460.094
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.091
regulation of immune system processGO:00026821760.087
transition metal ion transportGO:0000041160.084
response to external biotic stimulusGO:00432072930.083
gland developmentGO:00487321910.081
activation of innate immune responseGO:000221840.080
hematopoietic or lymphoid organ developmentGO:0048534570.079
regulation of melanization defense responseGO:003500760.078
regulation of humoral immune responseGO:0002920510.073
antimicrobial peptide productionGO:0002775460.069
hemolymph coagulationGO:0042381100.068
melanin metabolic processGO:0006582470.067
regulation of immune effector processGO:0002697520.066
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.066
immune response activating signal transductionGO:000275720.064
hemocyte differentiationGO:0042386380.064
positive regulation of antimicrobial humoral responseGO:0002760280.062
positive regulation of biosynthetic processGO:00098913160.061
positive regulation of nitrogen compound metabolic processGO:00511733540.060
organonitrogen compound metabolic processGO:19015643180.058
endocytosisGO:00068973100.058
positive regulation of cellular biosynthetic processGO:00313283160.057
pigment metabolic processGO:0042440840.057
positive regulation of antimicrobial peptide productionGO:0002225280.055
innate immune response activating signal transductionGO:000275820.055
gland morphogenesisGO:00226121450.054
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.054
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.054
positive regulation of response to biotic stimulusGO:0002833310.053
peptide biosynthetic processGO:0043043420.053
appendage developmentGO:00487364010.052
organonitrogen compound biosynthetic processGO:19015661170.051
negative regulation of cell differentiationGO:00455961430.051
response to lipopolysaccharideGO:003249640.051
defense response to fungusGO:0050832480.051
regulation of multicellular organismal developmentGO:20000264140.051
kidney developmentGO:000182230.050
negative regulation of immune system processGO:0002683500.050
glycosaminoglycan catabolic processGO:000602730.049
vesicle mediated transportGO:00161923810.048
embryonic pattern specificationGO:00098801740.048
regulation of antimicrobial humoral responseGO:0002759500.048
catabolic processGO:00090564090.048
regulation of antimicrobial peptide biosynthetic processGO:0002805380.046
antimicrobial humoral responseGO:0019730990.046
body morphogenesisGO:001017120.046
response to woundingGO:0009611940.045
lipopolysaccharide mediated signaling pathwayGO:003166310.045
salivary gland morphogenesisGO:00074351450.045
positive regulation of response to external stimulusGO:0032103440.044
regionalizationGO:00030024160.044
single organism behaviorGO:00447083910.044
defense response to other organismGO:00985422250.044
sleepGO:0030431490.043
adult behaviorGO:00305341370.042
response to peptidoglycanGO:003249420.041
regulation of production of molecular mediator of immune responseGO:0002700440.041
antibacterial peptide biosynthetic processGO:0002780220.041
response to glucoseGO:000974920.040
organic substance catabolic processGO:19015753080.040
exocrine system developmentGO:00352721620.040
regulation of hemocyte differentiationGO:0045610220.039
phosphorylationGO:00163102940.039
intracellular signal transductionGO:00355563000.038
carbohydrate derivative catabolic processGO:19011361180.038
regulation of antibacterial peptide biosynthetic processGO:0002808220.038
hemopoiesisGO:0030097460.038
positive regulation of immune effector processGO:0002699280.038
regulation of response to stressGO:00801342000.037
regulation of cellular amide metabolic processGO:0034248390.036
immune system developmentGO:0002520570.036
positive regulation of response to stimulusGO:00485843230.036
response to hexoseGO:000974630.035
cellular response to lipopolysaccharideGO:007122230.035
connective tissue developmentGO:006144830.035
positive regulation of signalingGO:00230562430.035
antimicrobial peptide biosynthetic processGO:0002777380.035
taxisGO:00423303040.035
positive regulation of defense responseGO:0031349590.035
regulation of immune responseGO:00507761180.034
regulation of antibacterial peptide productionGO:0002786220.034
regulation of cellular amine metabolic processGO:003323830.034
ion transmembrane transportGO:00342201220.034
salivary gland developmentGO:00074311620.034
positive regulation of signal transductionGO:00099672230.033
cell proliferationGO:00082832990.033
positive regulation of immune responseGO:0050778630.032
positive regulation of cell communicationGO:00106472500.032
cellular catabolic processGO:00442483720.032
regulation of antimicrobial peptide productionGO:0002784440.031
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.031
regulation of multi organism processGO:00439001310.031
regulation of intracellular signal transductionGO:19025312360.031
wound healingGO:0042060750.031
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.030
amide biosynthetic processGO:0043604420.030
blastoderm segmentationGO:00073501590.030
transmembrane transportGO:00550851390.030
macromolecule catabolic processGO:00090571610.029
cellular response to biotic stimulusGO:007121640.029
negative regulation of multicellular organismal processGO:00512411420.029
defense response to gram negative bacteriumGO:0050829940.029
response to monosaccharideGO:003428440.028
locomotory behaviorGO:00076261760.028
circadian sleep wake cycle sleepGO:0050802230.028
organonitrogen compound catabolic processGO:19015651280.028
cellular amide metabolic processGO:0043603800.028
negative regulation of rna metabolic processGO:00512532510.027
nucleobase containing small molecule metabolic processGO:00550861740.027
axis specificationGO:00097981670.027
response to extracellular stimulusGO:00099911160.027
jnk cascadeGO:0007254500.026
regulation of transcription from rna polymerase ii promoterGO:00063573780.026
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.026
eye developmentGO:00016543230.026
organic hydroxy compound metabolic processGO:1901615830.025
cellular response to molecule of bacterial originGO:007121930.025
anterior posterior pattern specificationGO:00099521360.025
negative regulation of calcium ion importGO:009028120.025
response to oxygen containing compoundGO:19017002000.025
regulation of phosphate metabolic processGO:00192202100.024
kidney morphogenesisGO:006099330.024
cation transportGO:00068121100.024
rhythmic processGO:00485111060.024
positive regulation of rna metabolic processGO:00512542710.024
response to organic substanceGO:00100332840.023
maintenance of gastrointestinal epitheliumGO:003027730.023
transcription from rna polymerase ii promoterGO:00063663680.023
phagocytosisGO:00069092150.023
response to starvationGO:0042594970.022
regulation of cell differentiationGO:00455953020.022
regulation of localizationGO:00328792750.022
cell recognitionGO:00080371020.022
homeostatic processGO:00425921990.022
positive regulation of defense response to bacteriumGO:1900426230.022
cardioblast differentiationGO:0010002200.021
organic substance transportGO:00717022570.021
response to nutrient levelsGO:00316671140.021
gastrulation with mouth forming firstGO:0001703360.021
cellular nitrogen compound catabolic processGO:00442701650.021
developmental programmed cell deathGO:00106231380.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
cation transmembrane transportGO:0098655880.021
mesenchymal cell differentiationGO:004876210.021
regulation of response to external stimulusGO:00321011150.021
positive regulation of multi organism processGO:0043902400.021
adult locomotory behaviorGO:0008344760.021
regulation of stress activated protein kinase signaling cascadeGO:0070302420.020
ribonucleoside metabolic processGO:00091191270.020
single organism catabolic processGO:00447122280.020
positive regulation of macromolecule metabolic processGO:00106044050.020
stem cell differentiationGO:00488631170.020
compound eye developmentGO:00487493070.020
stress activated mapk cascadeGO:0051403520.020
detection of stimulusGO:00516061560.020
metal ion transportGO:0030001740.020
antibacterial peptide productionGO:0002778220.020
organelle fissionGO:00482853400.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
purine ribonucleotide metabolic processGO:00091501450.020
positive regulation of macromolecule biosynthetic processGO:00105572830.019
wing disc morphogenesisGO:00074723440.019
single organismal cell cell adhesionGO:0016337450.019
inorganic ion transmembrane transportGO:0098660730.019
positive regulation of cellular component organizationGO:00511301560.019
positive regulation of gene expressionGO:00106282900.019
dorsal ventral pattern formationGO:00099531330.019
memoryGO:0007613940.019
regulation of innate immune responseGO:0045088710.019
regulation of stress activated mapk cascadeGO:0032872410.019
carbohydrate derivative metabolic processGO:19011352170.019
larval lymph gland hemopoiesisGO:0035167170.019
kidney epithelium developmentGO:007207330.019
positive regulation of cellular component biogenesisGO:0044089800.019
epithelial cell differentiationGO:00308553220.019
post embryonic hemopoiesisGO:0035166170.019
segmentationGO:00352822070.019
organic cyclic compound catabolic processGO:19013611680.018
regulation of phosphorylationGO:00423251470.018
nephron developmentGO:007200630.018
regulation of organ morphogenesisGO:2000027780.018
glycosyl compound metabolic processGO:19016571270.018
mitotic spindle organizationGO:00070522200.018
negative regulation of immune responseGO:0050777390.018
regulation of cell proliferationGO:00421271630.018
mapk cascadeGO:00001651070.018
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.018
positive regulation of cellular amide metabolic processGO:0034250260.018
protein modification processGO:00362114380.018
endomembrane system organizationGO:00102561190.018
endoderm formationGO:000170630.018
regulation of epithelial cell proliferationGO:005067840.018
regulation of phosphorus metabolic processGO:00511742100.018
positive regulation of immune system processGO:0002684680.018
heterocycle catabolic processGO:00467001660.018
anterior posterior axis specification embryoGO:00085951030.017
positive regulation of rna biosynthetic processGO:19026802660.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
nucleoside catabolic processGO:00091641120.017
peptidoglycan catabolic processGO:000925330.017
regulation of cell deathGO:00109411730.017
cellular amine metabolic processGO:0044106120.017
segment specificationGO:0007379330.017
cellular amino acid metabolic processGO:0006520610.017
regulation of transportGO:00510491810.017
regulation of defense responseGO:00313471020.017
cell deathGO:00082192790.016
aromatic compound catabolic processGO:00194391660.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
imaginal disc derived wing morphogenesisGO:00074763370.016
spermatogenesisGO:00072832000.016
mesenchymal cell developmentGO:001403110.016
negative regulation of response to stimulusGO:00485852580.016
regulation of secondary metabolic processGO:004345570.016
cell divisionGO:00513012480.016
g protein coupled receptor signaling pathwayGO:00071861360.016
embryonic development via the syncytial blastodermGO:00017001480.016
detection of external biotic stimulusGO:009858120.016
regulation of response to biotic stimulusGO:0002831630.016
apoptotic process involved in morphogenesisGO:006056130.016
stress activated protein kinase signaling cascadeGO:0031098550.016
intracellular mrna localization involved in pattern specification processGO:0060810560.016
circadian sleep wake cycleGO:0042745280.015
nephron tubule developmentGO:007208030.015
neuromuscular synaptic transmissionGO:0007274670.015
neurological system processGO:00508773580.015
purine nucleoside metabolic processGO:00422781270.015
compound eye morphogenesisGO:00017452490.015
regulation of mapk cascadeGO:0043408920.015
positive regulation of melanization defense responseGO:003500810.015
negative regulation of gene expressionGO:00106293870.015
peptidoglycan metabolic processGO:000027030.015
regulation of jnk cascadeGO:0046328400.015
positive regulation of antibacterial peptide productionGO:0002803200.015
inorganic cation transmembrane transportGO:0098662610.015
regulation of circadian rhythmGO:0042752490.015
single organism intracellular transportGO:19025822070.015
convergent extensionGO:006002620.015
positive regulation of transcription dna templatedGO:00458932660.015
positive regulation of cell migrationGO:003033520.015
regulation of vesicle mediated transportGO:0060627590.015
small molecule metabolic processGO:00442813050.015
negative regulation of cellular metabolic processGO:00313243820.015
regulation of cellular ketone metabolic processGO:001056530.015
cell surface receptor signaling pathway involved in heart developmentGO:006131130.015
regulation of cellular amino acid metabolic processGO:000652100.015
carbohydrate metabolic processGO:0005975820.014
cognitionGO:00508901410.014
ribose phosphate metabolic processGO:00196931450.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of cellular response to stressGO:0080135890.014
regulation of gene silencingGO:0060968630.014
lymph gland developmentGO:0048542280.014
anterior posterior axis specificationGO:00099481090.014
regulation of protein metabolic processGO:00512462560.014
camera type eye developmentGO:004301040.014
nucleoside metabolic processGO:00091161270.014
regulation of synapse assemblyGO:0051963940.014
stem cell divisionGO:0017145690.014
endodermal cell differentiationGO:003598730.014
protein localizationGO:00081042840.014
nephron morphogenesisGO:007202830.014
negative regulation of signalingGO:00230572190.014
cellular component assembly involved in morphogenesisGO:00109271510.014
negative regulation of intracellular signal transductionGO:1902532570.014
regulation of cell cycle processGO:00105641810.014
organophosphate metabolic processGO:00196371950.014
cellular response to organic substanceGO:00713101320.014
positive regulation of developmental processGO:00510941430.014
nephron tubule morphogenesisGO:007207830.014
embryonic hemopoiesisGO:0035162260.014
nuclear divisionGO:00002803320.014
growthGO:00400073590.014
morphogenesis of embryonic epitheliumGO:0016331940.014
regulation of circadian sleep wake cycleGO:0042749250.014
nucleobase containing compound catabolic processGO:00346551650.014
skeletal muscle fiber developmentGO:004874130.014
deathGO:00162652840.014
myotube cell developmentGO:001490430.013
lateral inhibitionGO:00463312060.013
embryonic morphogenesisGO:00485982060.013
mesodermal cell migrationGO:000807870.013
single organism carbohydrate metabolic processGO:0044723720.013
cellular homeostasisGO:0019725800.013
male gamete generationGO:00482322010.013
catecholamine biosynthetic processGO:004242330.013
regulation of defense response to bacteriumGO:1900424300.013
carboxylic acid metabolic processGO:0019752920.013
regulation of cytoskeleton organizationGO:0051493890.013
organophosphate catabolic processGO:00464341120.013
cytoplasm organizationGO:0007028640.013
amine metabolic processGO:0009308120.013
purine containing compound metabolic processGO:00725211550.013
eye morphogenesisGO:00485922600.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
proteolysisGO:00065081920.013
protein transmembrane transportGO:007180640.013
digestive tract developmentGO:00485651490.013
cell cycle checkpointGO:0000075950.013
cellular cation homeostasisGO:0030003380.013
mrna processingGO:00063971040.013
metal ion homeostasisGO:0055065440.013
vacuolar transportGO:0007034130.013
morphogenesis of an epitheliumGO:00020092760.013
cellular response to oxygen containing compoundGO:1901701790.013
regulation of cellular component biogenesisGO:00440872010.013
regulation of catalytic activityGO:00507901850.012
nucleotide metabolic processGO:00091171610.012
gastrulation involving germ band extensionGO:0010004360.012
negative regulation of innate immune responseGO:0045824300.012
nucleoside phosphate metabolic processGO:00067531620.012
neuron projection guidanceGO:00974852410.012
zinc ion transportGO:000682950.012
protein phosphorylationGO:00064681690.012
aminoglycan catabolic processGO:000602660.012
regulation of programmed cell deathGO:00430671520.012
agingGO:00075681430.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
chromatin remodelingGO:0006338720.012
extrinsic apoptotic signaling pathwayGO:009719110.012
regulation of anatomical structure morphogenesisGO:00226032420.012
negative regulation of mitotic cell cycleGO:00459301090.012
long term memoryGO:0007616620.012
tube morphogenesisGO:00352391910.012
chromosome organizationGO:00512763600.012
circadian rhythmGO:00076231050.012
regulation of cellular protein metabolic processGO:00322682430.012
signal transduction by phosphorylationGO:00230141070.012
purine ribonucleoside metabolic processGO:00461281270.012
determination of adult lifespanGO:00083401370.012
circadian behaviorGO:0048512760.012
positive regulation of intracellular signal transductionGO:19025331160.012
positive regulation of catalytic activityGO:00430851180.012
secretionGO:00469031090.012
positive regulation of antifungal peptide biosynthetic processGO:000696750.012
protein complex localizationGO:003150340.012
ribonucleotide metabolic processGO:00092591450.012
nitrogen compound transportGO:0071705850.012
interspecies interaction between organismsGO:0044419160.012
positive regulation of molecular functionGO:00440931360.012
single organism cell adhesionGO:0098602470.012
glycosyl compound catabolic processGO:19016581120.011
regulation of extracellular matrix organizationGO:190305340.011
nucleoside triphosphate metabolic processGO:00091411200.011
actin cytoskeleton organizationGO:00300362060.011
purine containing compound catabolic processGO:00725231120.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
ribonucleoside catabolic processGO:00424541120.011
regulation of cell cycleGO:00517262910.011
dna metabolic processGO:00062592270.011
axon guidanceGO:00074112330.011
purine nucleoside catabolic processGO:00061521120.011
muscle tissue morphogenesisGO:006041520.011
cell cycle arrestGO:000705040.011
chitin based cuticle developmentGO:0040003490.011
camera type eye morphogenesisGO:004859320.011
embryonic organ developmentGO:0048568500.011
neuron recognitionGO:00080381010.011
muscle structure developmentGO:00610612240.011
rna processingGO:00063961470.011
neuroblast fate determinationGO:0007400120.011
muscle fiber developmentGO:0048747120.011
cation homeostasisGO:0055080510.011
zinc ion transmembrane transportGO:007157750.011
rhythmic behaviorGO:0007622760.011
negative regulation of phosphate metabolic processGO:0045936450.011
chemotaxisGO:00069352490.011
cellular ketone metabolic processGO:0042180240.011
negative regulation of cell communicationGO:00106482230.011
jak stat cascadeGO:0007259490.011
cellular protein modification processGO:00064644380.011
purine ribonucleoside catabolic processGO:00461301120.011
localization of cellGO:00516742570.011
cellular ion homeostasisGO:0006873390.011
organelle assemblyGO:00709251980.011
gene silencingGO:00164581380.011
circadian sleep wake cycle processGO:0022410240.011
response to copper ionGO:004668840.011
response to sterolGO:0036314340.011
protein transportGO:00150311550.011
compound eye photoreceptor developmentGO:0042051780.011
embryonic axis specificationGO:00005781070.010
neuroblast differentiationGO:0014016290.010
gastrulationGO:0007369700.010
transition metal ion homeostasisGO:0055076170.010
cell motilityGO:00488702510.010
regulation of organelle organizationGO:00330431960.010
nephron epithelium morphogenesisGO:007208830.010
programmed cell deathGO:00125012570.010
chemical homeostasisGO:0048878920.010
pole plasm mrna localizationGO:0019094490.010
rna splicingGO:0008380830.010
negative regulation of cellular biosynthetic processGO:00313272770.010
cellular response to hexose stimulusGO:007133110.010
negative regulation of rna biosynthetic processGO:19026792400.010
response to alcoholGO:0097305950.010
ion homeostasisGO:0050801550.010
catechol containing compound biosynthetic processGO:000971330.010
positive regulation of phosphate metabolic processGO:00459371390.010
oxoacid metabolic processGO:00434361030.010
single organism cellular localizationGO:19025801800.010
dna conformation changeGO:00711031050.010
ras protein signal transductionGO:0007265880.010
spindle organizationGO:00070512530.010
melanotic encapsulation of foreign targetGO:0035011300.010
positive regulation of cell motilityGO:200014730.010
muscle organ developmentGO:00075171270.010
regulation of hydrolase activityGO:0051336970.010
positive regulation of phosphorus metabolic processGO:00105621390.010
positive regulation of organelle organizationGO:0010638650.010
establishment or maintenance of cell polarityGO:00071631670.010
hematopoietic progenitor cell differentiationGO:000224410.010

l(3)mbn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
disease of metabolismDOID:001466700.026
acquired metabolic diseaseDOID:006015800.024
diabetes mellitusDOID:935100.023
carbohydrate metabolism diseaseDOID:005001300.023
glucose metabolism diseaseDOID:419400.023
musculoskeletal system diseaseDOID:1700.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
cardiovascular system diseaseDOID:128700.012
type 2 diabetes mellitusDOID:935200.012
sensory system diseaseDOID:005015500.011
nervous system diseaseDOID:86300.011
inherited metabolic disorderDOID:65500.011
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010