Drosophila melanogaster

79 known processes

Aos1 (Dmel_CG12276)

CG12276 gene product from transcript CG12276-RA

(Aliases: CG12276,Dmel\CG12276,Sae1,Dmaos1,SAE1,Aos,DmSae1,DmAos1,DmSAE1)

Aos1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell deathGO:00082192790.953
embryo development ending in birth or egg hatchingGO:00097921520.918
programmed cell deathGO:00125012570.902
regulation of organelle organizationGO:00330431960.889
macromolecule catabolic processGO:00090571610.692
catabolic processGO:00090564090.638
organic substance catabolic processGO:19015753080.631
development of primary sexual characteristicsGO:0045137500.624
mitotic sister chromatid segregationGO:0000070870.623
negative regulation of nitrogen compound metabolic processGO:00511722650.618
vesicle mediated transportGO:00161923810.613
deathGO:00162652840.602
mitotic spindle organizationGO:00070522200.570
negative regulation of gene expressionGO:00106293870.555
nuclear divisionGO:00002803320.545
regulation of cell deathGO:00109411730.542
regulation of cell cycleGO:00517262910.537
negative regulation of cellular metabolic processGO:00313243820.530
organelle fissionGO:00482853400.527
regulation of programmed cell deathGO:00430671520.512
reproductive structure developmentGO:0048608740.499
rna catabolic processGO:0006401370.491
single organism catabolic processGO:00447122280.481
regulation of molecular functionGO:00650092170.449
regulation of transcription from rna polymerase ii promoterGO:00063573780.440
gene silencingGO:00164581380.437
negative regulation of transcription dna templatedGO:00458922370.394
regulation of mitotic cell cycleGO:00073461900.338
regulation of apoptotic processGO:00429811300.338
positive regulation of cell communicationGO:00106472500.332
protein complex assemblyGO:00064612000.322
regulation of cell cycle processGO:00105641810.322
sister chromatid segregationGO:0000819920.321
positive regulation of macromolecule metabolic processGO:00106044050.316
posttranscriptional gene silencingGO:0016441460.303
proteolysisGO:00065081920.300
establishment of localization in cellGO:00516494020.299
positive regulation of signal transductionGO:00099672230.296
cell cycle phase transitionGO:00447701400.293
regulation of neurogenesisGO:00507671580.289
spindle organizationGO:00070512530.287
larval developmentGO:00021641040.281
endocytosisGO:00068973100.280
mitotic cell cycle phase transitionGO:00447721380.278
positive regulation of signalingGO:00230562430.278
regulation of protein metabolic processGO:00512462560.267
protein catabolic processGO:00301631010.247
regulation of chromosome segregationGO:0051983320.241
gonad developmentGO:0008406500.241
regulation of gene expression epigeneticGO:00400291280.232
regulation of multicellular organismal developmentGO:20000264140.231
reproductive system developmentGO:0061458740.230
positive regulation of response to stimulusGO:00485843230.228
regulation of meiosisGO:004002030.225
cellular catabolic processGO:00442483720.223
genitalia developmentGO:0048806260.222
cellular macromolecule catabolic processGO:00442651360.213
meiotic cell cycleGO:00513211710.196
modification dependent protein catabolic processGO:0019941780.195
chromosome segregationGO:00070591570.185
establishment of organelle localizationGO:00516561220.179
macromolecular complex assemblyGO:00650032560.178
mitotic nuclear divisionGO:00070672130.178
modification dependent macromolecule catabolic processGO:0043632790.161
single organism intracellular transportGO:19025822070.153
cellular nitrogen compound catabolic processGO:00442701650.153
negative regulation of apoptotic processGO:0043066630.149
gene silencing by mirnaGO:0035195220.147
regulation of cell divisionGO:0051302720.146
body morphogenesisGO:001017120.144
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregationGO:005131610.141
intermediate filament cytoskeleton organizationGO:004510410.137
heterocycle catabolic processGO:00467001660.136
negative regulation of cell cycleGO:00457861160.135
cellular macromolecular complex assemblyGO:00346221530.132
regulation of catalytic activityGO:00507901850.131
rna processingGO:00063961470.126
regulation of mitotic cell cycle phase transitionGO:19019901300.124
rna splicingGO:0008380830.123
apoptotic processGO:00069151590.118
photoreceptor cell differentiationGO:00465301700.114
cellular response to dna damage stimulusGO:00069742230.111
positive regulation of macromolecule biosynthetic processGO:00105572830.109
regulation of catabolic processGO:00098941700.107
positive regulation of rna biosynthetic processGO:19026802660.107
regulation of notch signaling pathwayGO:00085931000.106
posttranscriptional regulation of gene expressionGO:00106081450.105
intracellular transportGO:00469072280.104
positive regulation of molecular functionGO:00440931360.099
intermediate filament based processGO:004510310.095
regulation of intracellular signal transductionGO:19025312360.091
spindle assembly involved in mitosisGO:0090307500.091
sex differentiationGO:0007548810.087
prostanoid biosynthetic processGO:004645710.087
negative regulation of mitotic cell cycleGO:00459301090.085
negative regulation of programmed cell deathGO:0043069720.085
positive regulation of nitrogen compound metabolic processGO:00511733540.083
regulation of cellular catabolic processGO:00313291570.083
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.081
regulation of proteolysisGO:0030162870.080
posttranscriptional gene silencing by rnaGO:0035194450.078
nucleosome organizationGO:0034728590.078
metaphase anaphase transition of cell cycleGO:0044784280.076
cell proliferationGO:00082832990.075
organic cyclic compound catabolic processGO:19013611680.075
dorsal vessel heart proper cell fate commitmentGO:003505320.074
negative regulation of cellular biosynthetic processGO:00313272770.073
dna integrity checkpointGO:0031570810.073
negative regulation of rna biosynthetic processGO:19026792400.072
nucleoside phosphate metabolic processGO:00067531620.072
transcription from rna polymerase ii promoterGO:00063663680.072
gene silencing by rnaGO:0031047570.071
chromosome organizationGO:00512763600.071
negative regulation of response to stimulusGO:00485852580.071
protein modification processGO:00362114380.070
cytoplasmic transportGO:00164821300.070
organelle localizationGO:00516401480.069
proteolysis involved in cellular protein catabolic processGO:0051603830.069
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.067
organonitrogen compound metabolic processGO:19015643180.067
border follicle cell delaminationGO:003070930.066
cellular protein modification processGO:00064644380.065
nucleobase containing small molecule metabolic processGO:00550861740.065
notch signaling pathwayGO:00072191200.064
multicellular organismal reproductive behaviorGO:00330571100.063
negative regulation of neurogenesisGO:0050768530.063
regulation of hydrolase activityGO:0051336970.062
negative regulation of cell communicationGO:00106482230.061
intracellular signal transductionGO:00355563000.061
positive regulation of proteolysisGO:0045862520.060
mitotic sister chromatid separationGO:0051306300.059
regulation of phosphate metabolic processGO:00192202100.059
histone h2a acetylationGO:004396810.058
mrna cis splicing via spliceosomeGO:004529210.057
meiotic nuclear divisionGO:00071261510.055
nucleobase containing compound catabolic processGO:00346551650.054
protein phosphorylationGO:00064681690.054
regulation of cell proliferationGO:00421271630.054
ubiquitin dependent protein catabolic processGO:0006511780.053
cellular ketone metabolic processGO:0042180240.053
regulation of cell developmentGO:00602842150.052
protein complex biogenesisGO:00702712010.052
ovipositionGO:0018991190.052
protein localization to organelleGO:0033365820.052
mrna splicing via spliceosomeGO:0000398730.051
regulation of mitotic sister chromatid separationGO:0010965280.051
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.050
cellular protein catabolic processGO:0044257830.050
cell chemotaxis involved in malpighian tubule morphogenesisGO:006135230.049
mrna catabolic processGO:0006402330.049
compound eye morphogenesisGO:00017452490.047
peptidyl amino acid modificationGO:00181931050.047
response to oxygen containing compoundGO:19017002000.047
negative regulation of macromolecule biosynthetic processGO:00105582700.047
positive regulation of cell deathGO:0010942690.046
progression of morphogenetic furrow involved in compound eye morphogenesisGO:000745880.044
aromatic compound catabolic processGO:00194391660.044
negative regulation of signalingGO:00230572190.042
positive regulation of gene expressionGO:00106282900.042
regulation of sister chromatid segregationGO:0033045280.042
regulation of protein localizationGO:0032880760.042
purine ribonucleotide metabolic processGO:00091501450.041
endomembrane system organizationGO:00102561190.041
mrna metabolic processGO:00160711240.041
regulation of mrna splicing via spliceosomeGO:0048024640.039
small molecule metabolic processGO:00442813050.039
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.039
multi organism behaviorGO:00517051750.039
dna damage checkpointGO:0000077780.038
dendrite developmentGO:00163582040.038
negative regulation of nurse cell apoptotic processGO:004584920.038
cell motilityGO:00488702510.038
dendrite regenerationGO:003110420.036
developmental maturationGO:00217001720.036
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.034
positive regulation of neuron projection regenerationGO:007057230.034
negative regulation of nervous system developmentGO:0051961920.034
regulation of striated muscle contractionGO:000694220.034
regulation of cell cycle phase transitionGO:19019871300.034
regulation of cell differentiationGO:00455953020.033
gland developmentGO:00487321910.032
regulation of purine nucleotide metabolic processGO:1900542620.032
proteasomal protein catabolic processGO:0010498590.031
cell migrationGO:00164772380.031
positive regulation of catalytic activityGO:00430851180.031
positive regulation of protein modification processGO:0031401580.031
positive regulation of protein metabolic processGO:00512471280.031
positive regulation of epidermal growth factor activated receptor activityGO:004574110.031
dendrite morphogenesisGO:00488131990.031
regulation of neuron differentiationGO:00456641030.031
receptor mediated endocytosisGO:0006898210.031
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.031
purine nucleotide metabolic processGO:00061631460.030
histone methylationGO:0016571400.030
regulation of planar cell polarity pathway involved in axis elongationGO:200004020.030
rna transportGO:0050658460.030
negative regulation of organelle organizationGO:0010639560.030
rna localizationGO:00064031150.030
regulation of cellular component biogenesisGO:00440872010.029
negative regulation of developmental pigmentationGO:004808610.029
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356820.028
positive regulation of hydrolase activityGO:0051345780.028
positive regulation of transcription dna templatedGO:00458932660.028
negative regulation of nucleic acid templated transcriptionGO:19035072400.028
demethylationGO:007098860.027
regulation of mitotic sister chromatid segregationGO:0033047280.027
positive regulation of phosphorus metabolic processGO:00105621390.027
reproductive behaviorGO:00190981220.026
formation of a compartment boundaryGO:006028840.026
positive regulation of rna metabolic processGO:00512542710.026
protein destabilizationGO:003164820.026
regulation of response to stressGO:00801342000.026
positive regulation of cellular protein metabolic processGO:00322701180.026
chromatin organizationGO:00063252070.025
regulation of protein modification processGO:00313991120.025
negative regulation of eye photoreceptor cell developmentGO:004248030.025
cellular protein localizationGO:00346131600.025
g2 dna damage checkpointGO:0031572690.025
eye developmentGO:00016543230.024
small gtpase mediated signal transductionGO:0007264880.024
mitotic g2 m transition checkpointGO:0044818700.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
left right axis specificationGO:007098610.024
regulation of centriole replicationGO:004659920.024
cellular response to chemical stimulusGO:00708871990.024
histone exchangeGO:0043486210.024
activation of ral gtpase activityGO:003285910.023
compound eye photoreceptor cell differentiationGO:00017511400.023
negative regulation of cell deathGO:0060548810.023
ovulation cycleGO:004269810.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.023
nucleoside catabolic processGO:00091641120.022
molting cycleGO:0042303560.022
oocyte fate commitmentGO:004860020.022
regulation of proteasomal protein catabolic processGO:0061136390.022
oocyte morphogenesisGO:004860130.021
phospholipid transportGO:001591420.021
specification of segmental identity abdomenGO:000738540.021
carbohydrate derivative catabolic processGO:19011361180.021
positive regulation of cell maturationGO:190343120.021
homeostatic processGO:00425921990.021
Zebrafish
negative regulation of cellular component organizationGO:00511291080.021
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.021
mitotic cell cycle checkpointGO:0007093880.021
positive regulation of centrosome cycleGO:004660710.021
regulation of nucleotide metabolic processGO:0006140620.020
ribonucleoside catabolic processGO:00424541120.020
cellular homeostasisGO:0019725800.020
negative regulation of cell cycle phase transitionGO:19019881030.020
positive regulation of intracellular signal transductionGO:19025331160.020
negative regulation of biosynthetic processGO:00098902770.020
positive regulation of catabolic processGO:00098961050.020
regulation of nervous system developmentGO:00519602480.020
eye photoreceptor cell differentiationGO:00017541450.020
ribonucleotide catabolic processGO:00092611090.020
regulation of intracellular transportGO:0032386640.020
mrna cleavageGO:000637920.020
nucleotide catabolic processGO:00091661090.019
regulation of nucleotide catabolic processGO:0030811480.019
regulation of cellular localizationGO:00603411360.019
protein methylationGO:0006479430.018
dna metabolic processGO:00062592270.018
regulation of dna templated transcription elongationGO:0032784170.018
rna splicing via transesterification reactionsGO:0000375730.018
protein modification by small protein conjugationGO:0032446790.018
nucleotide metabolic processGO:00091171610.018
regulation of cellular protein metabolic processGO:00322682430.018
anterior head segmentationGO:003528830.018
spliceosomal snrnp assemblyGO:000038720.018
regulation of protein catabolic processGO:0042176550.018
positive regulation of pole plasm oskar mrna localizationGO:004585620.017
regulation of rac gtpase activityGO:003231410.017
chromatin modificationGO:00165681470.017
positive regulation of apoptotic processGO:0043065470.017
heart developmentGO:0007507820.017
immune system processGO:00023763470.017
Zebrafish
regulation of transcription from rna polymerase i promoterGO:000635640.017
chromatin remodelingGO:0006338720.017
negative regulation of dna templated transcription initiationGO:200014310.017
hematopoietic stem cell differentiationGO:006021810.017
defense response to other organismGO:00985422250.017
nitric oxide metabolic processGO:004620910.017
ovarian follicle cell cell adhesionGO:000729940.017
regulation of homotypic cell cell adhesionGO:003411020.017
central nervous system developmentGO:00074172010.017
actin filament based processGO:00300292200.016
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.016
glycosyl compound catabolic processGO:19016581120.016
establishment of spindle orientationGO:0051294180.016
purine ribonucleotide catabolic processGO:00091541090.016
chitin based larval cuticle pattern formationGO:0035293110.016
regulation of gene silencingGO:0060968630.016
regulation of cellular response to stressGO:0080135890.016
negative regulation of developmental processGO:00510932010.016
regulation of transportGO:00510491810.016
regulation of meiotic cell cycle phase transitionGO:190199310.016
positive regulation of golgi to plasma membrane protein transportGO:004299820.016
positive regulation of programmed cell deathGO:0043068620.016
negative regulation of protein complex disassemblyGO:0043242230.016
synaptic transmissionGO:00072682880.016
phosphorylationGO:00163102940.016
regulation of chromosome organizationGO:0033044640.016
ribonucleoprotein complex biogenesisGO:0022613310.015
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.015
negative regulation of ras gtpase activityGO:003426110.015
single organism behaviorGO:00447083910.015
neural retina developmentGO:000340740.015
positive regulation of cellular biosynthetic processGO:00313283160.014
negative regulation of meiotic cell cycleGO:005144720.014
regulation of reactive oxygen species biosynthetic processGO:190342600.014
multi organism reproductive behaviorGO:00447051210.014
establishment or maintenance of polarity of larval imaginal disc epitheliumGO:001633630.014
camera type eye developmentGO:004301040.014
protein transportGO:00150311550.014
negative regulation of neurotransmitter secretionGO:004692920.014
regulation of ral gtpase activityGO:003231510.014
response to organic substanceGO:00100332840.014
regulation of mrna metabolic processGO:1903311720.014
regulation of cellular amino acid metabolic processGO:000652100.013
specification of segmental identity antennal segmentGO:000738320.013
meiotic nuclear envelope disassemblyGO:005107820.013
covalent chromatin modificationGO:00165691060.013
response to symbiontGO:000960860.013
positive regulation of phosphate metabolic processGO:00459371390.013
positive regulation of bindingGO:005109940.013
negative regulation of catabolic processGO:0009895360.013
regulation of cdc42 protein signal transductionGO:003248930.013
directional locomotionGO:003305810.013
compound eye developmentGO:00487493070.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
negative regulation of compound eye photoreceptor developmentGO:004531630.013
regulation of purine nucleotide catabolic processGO:0033121480.013
negative regulation of signal transductionGO:00099682060.013
meiotic spindle checkpointGO:004477910.012
mrna processingGO:00063971040.012
macropinocytosisGO:004435110.012
oocyte constructionGO:00073081120.012
mitotic g2 dna damage checkpointGO:0007095690.012
response to external biotic stimulusGO:00432072930.012
response to organic cyclic compoundGO:0014070890.012
glycosyl compound metabolic processGO:19016571270.012
protein localizationGO:00081042840.012
protein homooligomerizationGO:005126070.012
nucleoside triphosphate catabolic processGO:00091431080.012
ncrna metabolic processGO:0034660430.012
reactive oxygen species biosynthetic processGO:190340900.012
multicellular organismal agingGO:00102591400.012
salivary gland cell autophagic cell deathGO:0035071830.011
release of cytoplasmic sequestered nf kappabGO:000858810.011
gene loopingGO:009020220.011
mitotic dna integrity checkpointGO:0044774750.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
negative regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:001705510.011
regulation of localizationGO:00328792750.011
response to oxidative stressGO:0006979860.011
regulation of phosphatase activityGO:001092130.011
regulation of rna stabilityGO:004348740.011
positive regulation of cellular catabolic processGO:0031331950.011
mitotic dna damage checkpointGO:0044773740.011
regulation of histone phosphorylationGO:003312710.011
organelle assemblyGO:00709251980.011
meiotic dna repair synthesisGO:000071130.011
response to red lightGO:001011420.011
regulation of ran gtpase activityGO:003231610.011
regulation of cohesin localization to chromatinGO:007192220.011
positive regulation of hemocyte differentiationGO:004561210.011
histone h4 acetylation involved in response to dna damage stimulusGO:200077610.011
organophosphate catabolic processGO:00464341120.010
metaphase anaphase transition of mitotic cell cycleGO:0007091280.010
regulation of hematopoietic stem cell differentiationGO:190203610.010
regulation of phosphoprotein phosphatase activityGO:004366630.010
oocyte axis specificationGO:00073091080.010
regulation of phosphorus metabolic processGO:00511742100.010
asymmetric neuroblast division resulting in ganglion mother cell formationGO:005506020.010
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063310.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.010
positive regulation of transcription from rna polymerase i promoterGO:004594330.010
peptidyl serine modificationGO:001820970.010
negative regulation of mrna 3 end processingGO:003144130.010

Aos1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
reproductive organ cancerDOID:19300.033
organ system cancerDOID:005068600.033
ovarian cancerDOID:239400.033
cancerDOID:16200.033
disease of cellular proliferationDOID:1456600.033
female reproductive organ cancerDOID:12000.033
respiratory system cancerDOID:005061500.032
dysostosisDOID:193400.025
brachydactylyDOID:005058100.025
bone development diseaseDOID:008000600.025
bone diseaseDOID:008000100.025
disease of anatomical entityDOID:700.025
connective tissue diseaseDOID:6500.025
musculoskeletal system diseaseDOID:1700.025
artery diseaseDOID:005082800.025
aortic diseaseDOID:52000.025
vascular diseaseDOID:17800.025
aortic aneurysmDOID:362700.025
cardiovascular system diseaseDOID:128700.025
reproductive system diseaseDOID:1500.014
female reproductive system diseaseDOID:22900.014
ovarian diseaseDOID:110000.014
endocrine gland cancerDOID:17000.014
thyroid cancerDOID:178100.014
muscular diseaseDOID:008000000.012
intrinsic cardiomyopathyDOID:006003600.012
arrhythmogenic right ventricular cardiomyopathyDOID:005043100.012
cardiomyopathyDOID:005070000.012
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
heart diseaseDOID:11400.012
syndromeDOID:22500.012
charge syndromeDOID:005083400.012
premature ovarian failureDOID:542600.011