IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG14544 (Dmel_CG14544)

CG14544 gene product from transcript CG14544-RA

(Aliases: Dmel\CG14544)

Entrez: 43170
FLYBASE: FBgn0039407
UniProtKB: Q9VBH7

Process Predictions
Disease Predictions

CG14544 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
lateral inhibition	GO:0046331	206	0.232
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.189
aromatic compound catabolic process	GO:0019439	166	0.182
ncrna metabolic process	GO:0034660	43	0.171
rrna processing	GO:0006364	3	0.166
rna processing	GO:0006396	147	0.128
cellular nitrogen compound catabolic process	GO:0044270	165	0.099
mrna metabolic process	GO:0016071	124	0.097
organic cyclic compound catabolic process	GO:1901361	168	0.093
heterocycle catabolic process	GO:0046700	166	0.090
cell death	GO:0008219	279	0.067
regionalization	GO:0003002	416	0.065
polyadenylation dependent ncrna catabolic process	GO:0043634	1	0.062
mrna catabolic process	GO:0006402	33	0.057
single organism membrane organization	GO:0044802	93	0.051
regulation of cell cycle phase transition	GO:1901987	130	0.050
trna processing	GO:0008033	3	0.049
cellular catabolic process	GO:0044248	372	0.049
defense response	GO:0006952	300	0.048
vesicle mediated transport	GO:0016192	381	0.047
cellular response to dna damage stimulus	GO:0006974	223	0.046
macromolecular complex assembly	GO:0065003	256	0.045
purine ribonucleoside metabolic process	GO:0046128	127	0.044
immune response	GO:0006955	246	0.044
nucleobase containing compound catabolic process	GO:0034655	165	0.042
regulation of catalytic activity	GO:0050790	185	0.042
death	GO:0016265	284	0.041
ribonucleoprotein complex biogenesis	GO:0022613	31	0.041
posttranscriptional regulation of gene expression	GO:0010608	145	0.037
trna modification	GO:0006400	2	0.037
ncrna processing	GO:0034470	30	0.036
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.035
rna phosphodiester bond hydrolysis	GO:0090501	17	0.035
ncrna 3 end processing	GO:0043628	17	0.033
regulation of mitotic cell cycle	GO:0007346	190	0.033
catabolic process	GO:0009056	409	0.033
establishment of localization in cell	GO:0051649	402	0.033
regulation of molecular function	GO:0065009	217	0.032
mitotic dna integrity checkpoint	GO:0044774	75	0.030
transcription from rna polymerase ii promoter	GO:0006366	368	0.030
response to external biotic stimulus	GO:0043207	293	0.030
positive regulation of biosynthetic process	GO:0009891	316	0.030
apoptotic process	GO:0006915	159	0.030
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.030
cellular component assembly involved in morphogenesis	GO:0010927	151	0.029
gland development	GO:0048732	191	0.029
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.029
cellular macromolecule catabolic process	GO:0044265	136	0.029
homeostatic process	GO:0042592	199	0.029
rna catabolic process	GO:0006401	37	0.028
cellular macromolecular complex assembly	GO:0034622	153	0.028
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.028
positive regulation of catalytic activity	GO:0043085	118	0.027
organic substance catabolic process	GO:1901575	308	0.027
endocytosis	GO:0006897	310	0.027
dna integrity checkpoint	GO:0031570	81	0.027
trna transcription from rna polymerase iii promoter	GO:0042797	1	0.026
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	14	0.026
anterior posterior pattern specification	GO:0009952	136	0.024
camera type eye development	GO:0043010	4	0.024
regulation of phosphate metabolic process	GO:0019220	210	0.024
mrna processing	GO:0006397	104	0.024
mitotic g2 m transition checkpoint	GO:0044818	70	0.023
mitotic g2 dna damage checkpoint	GO:0007095	69	0.023
rna 3 end processing	GO:0031123	45	0.022
protein complex biogenesis	GO:0070271	201	0.022
purine nucleoside metabolic process	GO:0042278	127	0.022
mitotic cell cycle phase transition	GO:0044772	138	0.021
regulation of hydrolase activity	GO:0051336	97	0.021
regulation of cellular catabolic process	GO:0031329	157	0.021
growth	GO:0040007	359	0.020
ribose phosphate metabolic process	GO:0019693	145	0.020
macromolecule catabolic process	GO:0009057	161	0.020
developmental growth	GO:0048589	280	0.020
muscle structure development	GO:0061061	224	0.020
nucleoside phosphate metabolic process	GO:0006753	162	0.020
regulation of apoptotic process	GO:0042981	130	0.020
cell cycle checkpoint	GO:0000075	95	0.019
trna metabolic process	GO:0006399	5	0.019
positive regulation of macromolecule metabolic process	GO:0010604	405	0.019
phagocytosis	GO:0006909	215	0.018
regulation of cell cycle	GO:0051726	291	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
nuclear rna surveillance	GO:0071027	3	0.018
imaginal disc derived appendage development	GO:0048737	399	0.018
segmentation	GO:0035282	207	0.018
organonitrogen compound metabolic process	GO:1901564	318	0.018
embryonic pattern specification	GO:0009880	174	0.018
response to other organism	GO:0051707	293	0.018
positive regulation of rna metabolic process	GO:0051254	271	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.017
regulation of cell cycle process	GO:0010564	181	0.017
protein modification process	GO:0036211	438	0.017
purine containing compound catabolic process	GO:0072523	112	0.017
cell cycle phase transition	GO:0044770	140	0.017
response to biotic stimulus	GO:0009607	294	0.016
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.016
ribonucleoside catabolic process	GO:0042454	112	0.016
regulation of multicellular organismal development	GO:2000026	414	0.016
body morphogenesis	GO:0010171	2	0.016
protein complex assembly	GO:0006461	200	0.016
epithelial cell differentiation	GO:0030855	322	0.016
immune system process	GO:0002376	347	0.016
protein localization	GO:0008104	284	0.016
reproductive system development	GO:0061458	74	0.015
macromolecule methylation	GO:0043414	45	0.015
modification dependent macromolecule catabolic process	GO:0043632	79	0.015
small molecule metabolic process	GO:0044281	305	0.015
positive regulation of transcription dna templated	GO:0045893	266	0.015
intracellular transport	GO:0046907	228	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
blastoderm segmentation	GO:0007350	159	0.015
nucleoside metabolic process	GO:0009116	127	0.015
reproductive structure development	GO:0048608	74	0.015
negative regulation of cell cycle process	GO:0010948	109	0.015
glycosyl compound metabolic process	GO:1901657	127	0.014
mitotic cell cycle checkpoint	GO:0007093	88	0.014
organelle fission	GO:0048285	340	0.014
dna damage checkpoint	GO:0000077	78	0.014
positive regulation of cellular biosynthetic process	GO:0031328	316	0.014
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.014
purine nucleotide catabolic process	GO:0006195	109	0.014
axonogenesis	GO:0007409	290	0.014
g2 dna damage checkpoint	GO:0031572	69	0.014
nucleobase containing small molecule metabolic process	GO:0055086	174	0.014
nucleoside phosphate catabolic process	GO:1901292	110	0.014
ribonucleotide catabolic process	GO:0009261	109	0.014
organic substance transport	GO:0071702	257	0.014
phosphorylation	GO:0016310	294	0.013
positive regulation of signaling	GO:0023056	243	0.013
cellular protein modification process	GO:0006464	438	0.013
notch signaling pathway	GO:0007219	120	0.013
branching morphogenesis of an epithelial tube	GO:0048754	45	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
developmental maturation	GO:0021700	172	0.013
transmembrane transport	GO:0055085	139	0.013
larval development	GO:0002164	104	0.013
organophosphate metabolic process	GO:0019637	195	0.013
wing disc morphogenesis	GO:0007472	344	0.013
post embryonic appendage morphogenesis	GO:0035120	385	0.013
regulation of response to stress	GO:0080134	200	0.013
secretion	GO:0046903	109	0.012
positive regulation of molecular function	GO:0044093	136	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
methylation	GO:0032259	47	0.012
mitotic dna damage checkpoint	GO:0044773	74	0.012
dna metabolic process	GO:0006259	227	0.012
regulation of programmed cell death	GO:0043067	152	0.012
regulation of cell death	GO:0010941	173	0.012
kidney development	GO:0001822	3	0.012
oocyte anterior posterior axis specification	GO:0007314	72	0.012
tissue morphogenesis	GO:0048729	297	0.012
membrane organization	GO:0061024	112	0.012
defense response to other organism	GO:0098542	225	0.012
regulation of cellular protein metabolic process	GO:0032268	243	0.012
nucleotide catabolic process	GO:0009166	109	0.012
carbohydrate derivative biosynthetic process	GO:1901137	85	0.012
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.012
axon development	GO:0061564	297	0.012
rna methylation	GO:0001510	2	0.011
organelle assembly	GO:0070925	198	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
positive regulation of gene expression	GO:0010628	290	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
organelle localization	GO:0051640	148	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
appendage development	GO:0048736	401	0.011
purine ribonucleotide metabolic process	GO:0009150	145	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
negative regulation of cell cycle phase transition	GO:1901988	103	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
positive regulation of cell communication	GO:0010647	250	0.011
chromosome organization	GO:0051276	360	0.010
single organism intracellular transport	GO:1902582	207	0.010
carbohydrate derivative catabolic process	GO:1901136	118	0.010
negative regulation of multicellular organismal process	GO:0051241	142	0.010
mitotic nuclear division	GO:0007067	213	0.010
regulation of reproductive process	GO:2000241	54	0.010
protein phosphorylation	GO:0006468	169	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.010
cell proliferation	GO:0008283	299	0.010
purine nucleotide metabolic process	GO:0006163	146	0.010
rna transport	GO:0050658	46	0.010
regulation of cell differentiation	GO:0045595	302	0.010

CG14544 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.031
disease of anatomical entity	DOID:7	0.015
inherited metabolic disorder	DOID:655	0.010

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