Drosophila melanogaster

0 known processes

PyK (Dmel_CG7070)

Pyruvate kinase

(Aliases: CG7070,PYK,Pyk,Dmel\CG7070)

PyK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myoblast fusionGO:0007520430.985
syncytium formation by plasma membrane fusionGO:0000768430.983
striated muscle cell differentiationGO:0051146900.903
Worm
somatic muscle developmentGO:0007525660.902
nad metabolic processGO:001967410.893
syncytium formationGO:0006949430.871
nicotinamide nucleotide metabolic processGO:004649620.850
muscle cell differentiationGO:00426921030.840
Worm
muscle structure developmentGO:00610612240.825
Worm
thioester metabolic processGO:003538330.779
monocarboxylic acid metabolic processGO:0032787290.582
Yeast Mouse Rat
single organism carbohydrate metabolic processGO:0044723720.560
Yeast Mouse Rat
pyridine nucleotide metabolic processGO:001936220.559
myotube differentiationGO:0014902460.551
organic acid metabolic processGO:00060821030.473
Yeast Mouse Rat
carbohydrate catabolic processGO:001605270.452
Yeast Mouse Rat
small molecule metabolic processGO:00442813050.446
Yeast Mouse Rat
organonitrogen compound metabolic processGO:19015643180.389
Rat
oxidoreduction coenzyme metabolic processGO:000673320.377
nucleotide metabolic processGO:00091171610.327
Rat
catabolic processGO:00090564090.306
Yeast Mouse Rat
pyridine containing compound metabolic processGO:007252430.305
single organism catabolic processGO:00447122280.259
Yeast Mouse Rat
oxoacid metabolic processGO:00434361030.243
Yeast Mouse Rat
nucleobase containing small molecule metabolic processGO:00550861740.236
Rat
oxidation reduction processGO:00551141230.226
pyruvate metabolic processGO:000609070.226
Yeast Mouse Rat
organic substance catabolic processGO:19015753080.218
Yeast Mouse Rat
acyl coa metabolic processGO:000663730.213
carboxylic acid metabolic processGO:0019752920.209
Yeast Mouse Rat
immune responseGO:00069552460.193
organophosphate metabolic processGO:00196371950.189
Rat
generation of precursor metabolites and energyGO:0006091420.170
Yeast Mouse Rat
thioester biosynthetic processGO:003538420.153
citrate metabolic processGO:000610100.124
negative regulation of cellular metabolic processGO:00313243820.122
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.100
programmed cell deathGO:00125012570.100
embryo development ending in birth or egg hatchingGO:00097921520.099
Worm
nucleoside metabolic processGO:00091161270.098
Rat
energy derivation by oxidation of organic compoundsGO:0015980320.092
purine nucleoside metabolic processGO:00422781270.089
Rat
purine nucleoside monophosphate metabolic processGO:0009126500.086
Rat
response to organic substanceGO:00100332840.084
Rat
negative regulation of gene expressionGO:00106293870.078
synapse assemblyGO:00074161430.078
organophosphate catabolic processGO:00464341120.078
posttranscriptional regulation of gene expressionGO:00106081450.077
compound eye developmentGO:00487493070.073
regulation of protein metabolic processGO:00512462560.073
muscle cell developmentGO:0055001500.072
Worm
negative regulation of macromolecule biosynthetic processGO:00105582700.070
ribose phosphate metabolic processGO:00196931450.070
Rat
glycolytic processGO:000609660.069
Yeast Mouse Rat
acyl coa biosynthetic processGO:007161620.069
response to abiotic stimulusGO:00096283410.069
Rat
purine containing compound metabolic processGO:00725211550.067
Rat
tricarboxylic acid metabolic processGO:007235010.066
single organism biosynthetic processGO:00447112060.063
Rat
nucleoside catabolic processGO:00091641120.062
negative regulation of cellular biosynthetic processGO:00313272770.060
organic cyclic compound catabolic processGO:19013611680.058
negative regulation of biosynthetic processGO:00098902770.057
regulation of cell cycleGO:00517262910.056
carbohydrate metabolic processGO:0005975820.055
Yeast Mouse Rat
response to monosaccharideGO:003428440.053
Rat
nucleoside phosphate metabolic processGO:00067531620.053
Rat
nucleobase containing compound catabolic processGO:00346551650.050
heterocycle catabolic processGO:00467001660.050
cellular component assembly involved in morphogenesisGO:00109271510.050
Worm
purine nucleotide metabolic processGO:00061631460.049
Rat
immune system processGO:00023763470.048
spermatid developmentGO:0007286980.048
rho protein signal transductionGO:0007266140.048
defense response to gram negative bacteriumGO:0050829940.048
aromatic compound catabolic processGO:00194391660.047
tube morphogenesisGO:00352391910.046
vesicle mediated transportGO:00161923810.046
Fly
skeletal muscle fiber developmentGO:004874130.045
glycosyl compound metabolic processGO:19016571270.045
Rat
negative regulation of epithelial cell proliferationGO:005068040.044
ribonucleoside catabolic processGO:00424541120.043
negative regulation of translationGO:0017148280.042
regulation of immune system processGO:00026821760.041
spermatogenesisGO:00072832000.041
purine nucleoside triphosphate metabolic processGO:00091441190.041
Rat
carbohydrate derivative metabolic processGO:19011352170.040
Rat
phagocytosisGO:00069092150.040
Fly
tube developmentGO:00352952440.038
morphogenesis of a branching structureGO:0001763450.038
translationGO:0006412690.038
organonitrogen compound catabolic processGO:19015651280.037
larval developmentGO:00021641040.037
Worm
single organism carbohydrate catabolic processGO:004472470.037
Yeast Mouse Rat
negative regulation of gene expression epigeneticGO:0045814770.036
regulation of developmental growthGO:00486381740.035
response to oxygen containing compoundGO:19017002000.035
Rat
agingGO:00075681430.035
Worm
nucleoside triphosphate metabolic processGO:00091411200.035
Rat
regulation of immune responseGO:00507761180.034
chaeta developmentGO:0022416970.034
regulation of cell developmentGO:00602842150.034
cofactor metabolic processGO:0051186130.034
response to glucoseGO:000974920.034
Rat
anatomical structure homeostasisGO:0060249970.034
regulation of organelle organizationGO:00330431960.033
negative regulation of cellular protein metabolic processGO:0032269850.033
apoptotic processGO:00069151590.033
cellular catabolic processGO:00442483720.033
negative regulation of response to stimulusGO:00485852580.033
regulation of response to stressGO:00801342000.033
cellular response to organic substanceGO:00713101320.032
Rat
body morphogenesisGO:001017120.032
nucleoside monophosphate metabolic processGO:0009123520.032
Rat
protein complex biogenesisGO:00702712010.032
Worm
striated muscle cell developmentGO:0055002500.032
Worm
striated muscle myosin thick filament assemblyGO:007168830.032
Worm
positive regulation of immune system processGO:0002684680.031
regulation of growthGO:00400082330.031
regulation of translationGO:0006417560.031
cellular response to chemical stimulusGO:00708871990.031
Rat
morphogenesis of a branching epitheliumGO:0061138450.031
glutamate metabolic processGO:000653650.030
purine nucleoside monophosphate biosynthetic processGO:000912730.029
Rat
synapse organizationGO:00508081960.029
biological adhesionGO:00226101380.028
salivary gland developmentGO:00074311620.028
positive regulation of programmed cell deathGO:0043068620.027
branching morphogenesis of an epithelial tubeGO:0048754450.027
mitotic cell cycle phase transitionGO:00447721380.027
regulation of catabolic processGO:00098941700.027
positive regulation of cellular component organizationGO:00511301560.027
regulation of programmed cell deathGO:00430671520.026
cell deathGO:00082192790.026
purine ribonucleoside triphosphate catabolic processGO:00092071080.026
regulation of cell differentiationGO:00455953020.026
phosphorylationGO:00163102940.026
Yeast Mouse Rat
cytoplasmic microtubule organizationGO:0031122220.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
macromolecule catabolic processGO:00090571610.025
lipid localizationGO:0010876540.025
regulation of catalytic activityGO:00507901850.024
positive regulation of cellular component biogenesisGO:0044089800.024
regulation of protein complex assemblyGO:0043254420.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
Rat
actin filament based processGO:00300292200.024
Worm
small molecule catabolic processGO:0044282210.024
imaginal disc derived wing morphogenesisGO:00074763370.023
multicellular organismal agingGO:00102591400.023
Worm
glycosyl compound catabolic processGO:19016581120.023
mitotic sister chromatid segregationGO:0000070870.023
gene silencingGO:00164581380.023
purine ribonucleoside triphosphate metabolic processGO:00092051190.023
Rat
negative regulation of protein metabolic processGO:0051248850.023
negative regulation of multicellular organismal processGO:00512411420.022
purine containing compound catabolic processGO:00725231120.022
eye developmentGO:00016543230.022
positive regulation of developmental growthGO:0048639620.022
male gamete generationGO:00482322010.022
neurotransmitter receptor metabolic processGO:004521330.022
cellular macromolecular complex assemblyGO:00346221530.022
Worm
cellular amino acid metabolic processGO:0006520610.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
lateral inhibitionGO:00463312060.021
developmental growthGO:00485892800.021
Rat
organic acid transportGO:0015849180.021
determination of adult lifespanGO:00083401370.021
Worm
epithelial tube morphogenesisGO:0060562880.021
purine ribonucleoside catabolic processGO:00461301120.020
extrinsic apoptotic signaling pathwayGO:009719110.020
tissue morphogenesisGO:00487292970.020
cellular protein complex assemblyGO:0043623710.020
Worm
heart developmentGO:0007507820.020
wing disc pattern formationGO:0035222660.020
camera type eye developmentGO:004301040.020
regulation of anatomical structure sizeGO:00900661630.020
ribonucleoside metabolic processGO:00091191270.020
Rat
purine ribonucleotide catabolic processGO:00091541090.020
response to oxidative stressGO:0006979860.020
regulation of cellular catabolic processGO:00313291570.020
purine ribonucleotide metabolic processGO:00091501450.020
Rat
development of primary sexual characteristicsGO:0045137500.019
myofibril assemblyGO:0030239360.019
Worm
positive regulation of developmental processGO:00510941430.019
purine ribonucleoside metabolic processGO:00461281270.019
Rat
response to organophosphorusGO:004668320.019
Rat
regulation of apoptotic processGO:00429811300.019
response to decreased oxygen levelsGO:0036293580.019
Rat
single organism intracellular transportGO:19025822070.018
acetaldehyde metabolic processGO:000611750.018
eye antennal disc developmentGO:0035214600.018
regulation of neurogenesisGO:00507671580.017
nucleoside triphosphate catabolic processGO:00091431080.017
growthGO:00400073590.017
Rat
organic substance transportGO:00717022570.017
regulation of hydrolase activityGO:0051336970.017
regulation of multicellular organismal developmentGO:20000264140.017
kidney developmentGO:000182230.017
glucose metabolic processGO:000600650.017
Rat
cell cycle phase transitionGO:00447701400.016
ribonucleotide catabolic processGO:00092611090.016
positive regulation of peptidase activityGO:0010952290.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
cell agingGO:000756920.016
negative regulation of signal transductionGO:00099682060.016
response to endogenous stimulusGO:00097191190.016
Rat
ribonucleoside biosynthetic processGO:004245530.016
Rat
proteolysisGO:00065081920.016
lipid storageGO:0019915380.016
mitotic nuclear divisionGO:00070672130.016
dendrite morphogenesisGO:00488131990.016
negative regulation of signalingGO:00230572190.016
regulation of cell deathGO:00109411730.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
cell cell signaling involved in cell fate commitmentGO:00451682100.016
regulation of cellular component biogenesisGO:00440872010.016
carbohydrate derivative biosynthetic processGO:1901137850.016
Rat
cell motilityGO:00488702510.016
macromolecular complex assemblyGO:00650032560.015
Worm
sex differentiationGO:0007548810.015
cellular carbohydrate catabolic processGO:004427520.015
cell adhesionGO:00071551360.015
regulation of nervous system developmentGO:00519602480.015
morphogenesis of an epitheliumGO:00020092760.015
negative regulation of neurogenesisGO:0050768530.015
regulation of cell proliferationGO:00421271630.014
urogenital system developmentGO:0001655720.014
purine nucleotide catabolic processGO:00061951090.014
carbohydrate derivative catabolic processGO:19011361180.014
response to nitrogen compoundGO:1901698900.014
Rat
homeostatic processGO:00425921990.014
imaginal disc derived appendage developmentGO:00487373990.014
monovalent inorganic cation transportGO:0015672400.014
neurological system processGO:00508773580.014
regulation of innate immune responseGO:0045088710.014
organic anion transportGO:0015711280.014
microtubule organizing center organizationGO:00310231680.014
chromatin silencingGO:0006342760.014
regulation of cell cycle phase transitionGO:19019871300.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
nucleoside phosphate catabolic processGO:19012921100.013
regulation of cellular component movementGO:0051270420.013
regulation of cellular amine metabolic processGO:003323830.013
notch signaling pathwayGO:00072191200.013
neuron deathGO:0070997270.013
regulation of mitotic cell cycleGO:00073461900.013
positive regulation of molecular functionGO:00440931360.013
ribonucleotide metabolic processGO:00092591450.013
Rat
negative regulation of cell cycleGO:00457861160.013
negative regulation of cell differentiationGO:00455961430.013
regulation of cellular protein metabolic processGO:00322682430.013
appendage morphogenesisGO:00351073970.013
positive regulation of growthGO:0045927750.013
protein complex assemblyGO:00064612000.013
Worm
renal system developmentGO:0072001720.013
wing disc morphogenesisGO:00074723440.013
cellular respirationGO:0045333260.013
regulation of cytoskeleton organizationGO:0051493890.012
negative regulation of developmental processGO:00510932010.012
maintenance of locationGO:0051235730.012
membrane organizationGO:00610241120.012
positive regulation of signal transductionGO:00099672230.012
negative regulation of programmed cell deathGO:0043069720.012
cellular nitrogen compound catabolic processGO:00442701650.012
carbohydrate biosynthetic processGO:0016051170.012
ubiquitin dependent protein catabolic processGO:0006511780.012
negative regulation of rna biosynthetic processGO:19026792400.012
regulation of nucleotide catabolic processGO:0030811480.012
sulfur compound biosynthetic processGO:0044272160.012
centrosome organizationGO:00512971630.012
ion transportGO:00068111450.012
regulation of cell cycle processGO:00105641810.012
positive regulation of cell communicationGO:00106472500.012
positive regulation of hydrolase activityGO:0051345780.012
response to oxygen levelsGO:0070482590.012
Rat
nucleotide catabolic processGO:00091661090.011
cellular carbohydrate metabolic processGO:0044262220.011
regulation of cellular component sizeGO:0032535980.011
muscle system processGO:0003012210.011
positive regulation of cell motilityGO:200014730.011
gland developmentGO:00487321910.011
Rat
sister chromatid segregationGO:0000819920.011
regulation of proteolysisGO:0030162870.011
integrin mediated signaling pathwayGO:000722930.011
spermatid differentiationGO:00485151140.011
detection of external stimulusGO:0009581660.011
endocytosisGO:00068973100.011
Fly
negative regulation of neural precursor cell proliferationGO:2000178270.011
glucan biosynthetic processGO:000925020.011
negative regulation of immune responseGO:0050777390.011
adherens junction organizationGO:0034332270.011
cellular protein catabolic processGO:0044257830.011
cellular aldehyde metabolic processGO:0006081100.011
establishment of protein localizationGO:00451841630.011
negative regulation of cellular component organizationGO:00511291080.011
positive regulation of multicellular organism growthGO:0040018210.011
response to biotic stimulusGO:00096072940.011
salivary gland morphogenesisGO:00074351450.011
defense response to bacteriumGO:00427421780.010
response to other organismGO:00517072930.010
ribonucleoside triphosphate biosynthetic processGO:000920120.010
Rat
gland morphogenesisGO:00226121450.010
cellular protein modification processGO:00064644380.010
purine nucleoside catabolic processGO:00061521120.010
embryonic morphogenesisGO:00485982060.010
organonitrogen compound biosynthetic processGO:19015661170.010
Rat
negative regulation of transcription dna templatedGO:00458922370.010
reproductive system developmentGO:0061458740.010
negative regulation of cell developmentGO:0010721620.010
cellular homeostasisGO:0019725800.010

PyK disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.090
inherited metabolic disorderDOID:65500.029
disease of metabolismDOID:001466700.029
glucose metabolism diseaseDOID:419400.023
carbohydrate metabolism diseaseDOID:005001300.023
acquired metabolic diseaseDOID:006015800.023
sensory system diseaseDOID:005015500.019
eye and adnexa diseaseDOID:149200.019
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.013
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011