Drosophila melanogaster

0 known processes

zen2 (Dmel_CG1048)

zerknullt-related

(Aliases: Dmel\CG1048,BG:DS00276.10,zpr,CG1048,z2)

zen2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of stimulus involved in sensory perceptionGO:0050906920.115
detection of chemical stimulusGO:0009593930.082
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.080
neurological system processGO:00508773580.050
protein heterooligomerizationGO:005129140.045
cell cell signaling involved in cell fate commitmentGO:00451682100.044
protein hydroxylationGO:001812610.041
negative regulation of cellular metabolic processGO:00313243820.040
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.038
Fly
immune responseGO:00069552460.038
negative regulation of nitrogen compound metabolic processGO:00511722650.038
Fly
positive regulation of cellular biosynthetic processGO:00313283160.035
Fly
axis specificationGO:00097981670.034
regionalizationGO:00030024160.034
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
Fly
protein modification processGO:00362114380.033
lateral inhibitionGO:00463312060.032
forebrain developmentGO:003090020.032
detection of stimulusGO:00516061560.032
endocytosisGO:00068973100.032
detection of chemical stimulus involved in sensory perceptionGO:0050907750.032
positive regulation of macromolecule metabolic processGO:00106044050.032
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.031
Fly
cellular protein modification processGO:00064644380.031
transcription from rna polymerase ii promoterGO:00063663680.031
Fly
embryonic pattern specificationGO:00098801740.031
sensory perceptionGO:00076001960.031
positive regulation of rna biosynthetic processGO:19026802660.031
Fly
post embryonic appendage morphogenesisGO:00351203850.031
regulation of localizationGO:00328792750.031
phagocytosisGO:00069092150.030
negative regulation of cellular biosynthetic processGO:00313272770.030
Fly
body morphogenesisGO:001017120.029
Worm
intracellular transportGO:00469072280.029
cell divisionGO:00513012480.029
positive regulation of rna metabolic processGO:00512542710.029
Fly
cell proliferationGO:00082832990.029
negative regulation of rna biosynthetic processGO:19026792400.028
Fly
segmentationGO:00352822070.028
positive regulation of biosynthetic processGO:00098913160.028
Fly
regulation of multi organism processGO:00439001310.028
establishment of localization in cellGO:00516494020.027
vesicle mediated transportGO:00161923810.027
axonogenesisGO:00074092900.027
Fly
immune system processGO:00023763470.027
compound eye developmentGO:00487493070.027
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.027
Fly
protein complex assemblyGO:00064612000.027
blastoderm segmentationGO:00073501590.027
innate immune responseGO:00450871440.027
olfactory behaviorGO:0042048970.027
humoral immune responseGO:00069591170.026
anterior posterior axis specification embryoGO:00085951030.026
developmental maturationGO:00217001720.026
response to other organismGO:00517072930.026
negative regulation of nucleic acid templated transcriptionGO:19035072400.026
Fly
response to organic substanceGO:00100332840.026
negative regulation of gene expressionGO:00106293870.026
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.026
Fly
negative regulation of biosynthetic processGO:00098902770.025
Fly
peptide metabolic processGO:0006518800.025
positive regulation of cell communicationGO:00106472500.025
anterior posterior axis specificationGO:00099481090.025
regulation of cell cycleGO:00517262910.025
chemosensory behaviorGO:00076351060.025
regulation of gene expression epigeneticGO:00400291280.024
wing disc morphogenesisGO:00074723440.024
sensory perception of chemical stimulusGO:00076061160.024
response to oxygen containing compoundGO:19017002000.024
camera type eye developmentGO:004301040.024
small molecule metabolic processGO:00442813050.024
appendage developmentGO:00487364010.024
macromolecular complex assemblyGO:00650032560.024
negative regulation of rna metabolic processGO:00512532510.024
Fly
anterior posterior pattern specificationGO:00099521360.024
protein complex biogenesisGO:00702712010.024
taxisGO:00423303040.024
Fly
embryonic axis specificationGO:00005781070.023
positive regulation of response to stimulusGO:00485843230.023
telencephalon developmentGO:002153720.023
sensory perception of smellGO:0007608800.022
regulation of cell cycle processGO:00105641810.022
epithelial cell developmentGO:00020642740.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
Fly
defense responseGO:00069523000.022
organic substance catabolic processGO:19015753080.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
Fly
regulation of transportGO:00510491810.022
response to abiotic stimulusGO:00096283410.022
organonitrogen compound metabolic processGO:19015643180.022
single organism intracellular transportGO:19025822070.022
eye developmentGO:00016543230.022
Fly
phosphorylationGO:00163102940.022
multi organism behaviorGO:00517051750.022
locomotory behaviorGO:00076261760.022
spinal cord developmentGO:002151010.021
tripartite regional subdivisionGO:00073511030.021
mitotic spindle organizationGO:00070522200.021
multi multicellular organism processGO:00447061230.021
regulation of immune system processGO:00026821760.021
response to external biotic stimulusGO:00432072930.021
epithelial cell differentiationGO:00308553220.021
regulation of mitotic cell cycleGO:00073461900.021
neuropeptide signaling pathwayGO:0007218450.020
columnar cuboidal epithelial cell developmentGO:00020662490.020
regulation of nervous system developmentGO:00519602480.020
Fly
axon developmentGO:00615642970.020
Fly
proteolysisGO:00065081920.020
sensory organ morphogenesisGO:00905962600.020
kidney developmentGO:000182230.020
negative regulation of signalingGO:00230572190.020
organic substance transportGO:00717022570.020
oocyte differentiationGO:00099941450.020
cell maturationGO:00484691440.020
protein localizationGO:00081042840.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
Fly
positive regulation of gene expressionGO:00106282900.019
Fly
mitotic nuclear divisionGO:00070672130.019
imaginal disc derived appendage developmentGO:00487373990.019
negative regulation of transcription dna templatedGO:00458922370.019
Fly
negative regulation of developmental processGO:00510932010.019
Fly
single organism behaviorGO:00447083910.019
oxoacid metabolic processGO:00434361030.019
imaginal disc derived wing morphogenesisGO:00074763370.019
cellular response to organic substanceGO:00713101320.019
nephron developmentGO:007200630.018
carboxylic acid metabolic processGO:0019752920.018
regulation of humoral immune responseGO:0002920510.018
organelle fissionGO:00482853400.018
retina development in camera type eyeGO:006004140.018
organic acid metabolic processGO:00060821030.018
regulation of phosphate metabolic processGO:00192202100.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
antimicrobial humoral responseGO:0019730990.018
microtubule based transportGO:0010970420.018
spindle organizationGO:00070512530.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
oocyte constructionGO:00073081120.018
oocyte developmentGO:00485991240.018
intracellular signal transductionGO:00355563000.018
cellular amide metabolic processGO:0043603800.018
nuclear divisionGO:00002803320.018
response to biotic stimulusGO:00096072940.018
regulation of response to external stimulusGO:00321011150.018
chromosome organizationGO:00512763600.018
organelle assemblyGO:00709251980.018
establishment or maintenance of cell polarityGO:00071631670.018
cellular response to chemical stimulusGO:00708871990.018
regulation of anatomical structure sizeGO:00900661630.017
regulation of cellular protein metabolic processGO:00322682430.017
regulation of embryonic developmentGO:0045995680.017
regulation of multicellular organismal developmentGO:20000264140.017
Fly
gene silencingGO:00164581380.017
cellular amino acid metabolic processGO:0006520610.017
cellular catabolic processGO:00442483720.017
eggshell formationGO:00307031050.017
cellular component assembly involved in morphogenesisGO:00109271510.017
reproductive behaviorGO:00190981220.017
positive regulation of signalingGO:00230562430.017
regulation of protein metabolic processGO:00512462560.017
hindgut developmentGO:0061525580.017
negative regulation of cell communicationGO:00106482230.017
protein processingGO:0016485680.017
regulation of response to stressGO:00801342000.016
tissue morphogenesisGO:00487292970.016
tube morphogenesisGO:00352391910.016
Fly
chemotaxisGO:00069352490.016
Fly
hindbrain developmentGO:003090220.016
axon guidanceGO:00074112330.016
Fly
negative regulation of signal transductionGO:00099682060.016
positive regulation of signal transductionGO:00099672230.016
notch signaling pathwayGO:00072191200.016
oocyte axis specificationGO:00073091080.016
regulation of immune responseGO:00507761180.016
digestive tract morphogenesisGO:00485461270.016
Fly
cytoplasm organizationGO:0007028640.016
regulation of phosphorus metabolic processGO:00511742100.016
cellular response to dna damage stimulusGO:00069742230.016
cytoskeleton dependent intracellular transportGO:0030705440.016
catabolic processGO:00090564090.016
regulation of phosphorylationGO:00423251470.016
acylglycerol catabolic processGO:004646430.016
connective tissue developmentGO:006144830.016
regulation of notch signaling pathwayGO:00085931000.015
single organism cellular localizationGO:19025801800.015
immune effector processGO:0002252980.015
single organism catabolic processGO:00447122280.015
response to woundingGO:0009611940.015
stem cell differentiationGO:00488631170.015
Fly
regulation of gene silencingGO:0060968630.015
synaptic transmissionGO:00072682880.015
negative regulation of response to stimulusGO:00485852580.015
wound healingGO:0042060750.015
embryo development ending in birth or egg hatchingGO:00097921520.015
Worm
peptidyl proline modificationGO:001820830.015
rna processingGO:00063961470.015
appendage morphogenesisGO:00351073970.015
compound eye morphogenesisGO:00017452490.015
microtubule based movementGO:0007018510.015
embryonic morphogenesisGO:00485982060.015
Fly
monocarboxylic acid transportGO:001571830.015
negative regulation of mitotic cell cycleGO:00459301090.015
regulation of cellular localizationGO:00603411360.015
negative regulation of cell cycle processGO:00109481090.015
maternal determination of anterior posterior axis embryoGO:0008358740.015
regulation of cell proliferationGO:00421271630.015
regulation of anatomical structure morphogenesisGO:00226032420.015
Fly
endodermal cell differentiationGO:003598730.015
mesenchymal cell differentiationGO:004876210.015
regulation of behaviorGO:0050795750.014
eye morphogenesisGO:00485922600.014
negative regulation of gene expression epigeneticGO:0045814770.014
negative regulation of nervous system developmentGO:0051961920.014
cellular macromolecule localizationGO:00707272200.014
chorion containing eggshell formationGO:00073041050.014
signal transduction by phosphorylationGO:00230141070.014
cation transportGO:00068121100.014
localization of cellGO:00516742570.014
neuron projection guidanceGO:00974852410.014
Fly
single organism biosynthetic processGO:00447112060.014
dorsal ventral axis specificationGO:0009950660.014
regulation of epithelial cell differentiationGO:003085640.014
cell motilityGO:00488702510.014
chromatin silencingGO:0006342760.014
homeostatic processGO:00425921990.014
positive regulation of transcription dna templatedGO:00458932660.014
Fly
negative regulation of cell cycleGO:00457861160.014
protein maturationGO:0051604710.014
regulation of production of molecular mediator of immune responseGO:0002700440.014
matingGO:00076181200.014
embryonic development via the syncytial blastodermGO:00017001480.014
response to lipopolysaccharideGO:003249640.014
macromolecule catabolic processGO:00090571610.014
mrna metabolic processGO:00160711240.013
developmental growthGO:00485892800.013
dna metabolic processGO:00062592270.013
regulation of cellular amine metabolic processGO:003323830.013
hindgut morphogenesisGO:0007442580.013
growthGO:00400073590.013
establishment of protein localizationGO:00451841630.013
regulation of intracellular signal transductionGO:19025312360.013
antimicrobial peptide productionGO:0002775460.013
central nervous system developmentGO:00074172010.013
regulation of response to biotic stimulusGO:0002831630.013
mesenchymal cell developmentGO:001403110.013
peptide biosynthetic processGO:0043043420.013
regulation of chromatin silencingGO:0031935360.013
negative regulation of cell differentiationGO:00455961430.013
Fly
regulation of reproductive processGO:2000241540.013
dorsal ventral pattern formationGO:00099531330.013
digestive system developmentGO:00551231490.013
Fly
rna localizationGO:00064031150.013
regulation of cellular amino acid metabolic processGO:000652100.013
spindle elongationGO:0051231830.013
endomembrane system organizationGO:00102561190.013
chromosome segregationGO:00070591570.013
cellular response to carbohydrate stimulusGO:007132240.013
digestive tract developmentGO:00485651490.013
Fly
adult behaviorGO:00305341370.013
defense response to other organismGO:00985422250.012
dendrite morphogenesisGO:00488131990.012
regulation of organelle organizationGO:00330431960.012
production of molecular mediator of immune responseGO:0002440460.012
negative regulation of multicellular organismal processGO:00512411420.012
Fly
positive regulation of cell motilityGO:200014730.012
cell deathGO:00082192790.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
Fly
behavioral response to painGO:004826630.012
regulation of defense responseGO:00313471020.012
positive regulation of transportGO:0051050920.012
gland developmentGO:00487321910.012
regulation of cellular ketone metabolic processGO:001056530.012
regulation of synapse structure and activityGO:00508031280.012
regulation of immune effector processGO:0002697520.012
ovarian follicle cell developmentGO:00307072480.012
positive regulation of cell migrationGO:003033520.012
regulation of antimicrobial humoral responseGO:0002759500.012
negative regulation of cellular component organizationGO:00511291080.012
camera type eye morphogenesisGO:004859320.012
mapk cascadeGO:00001651070.012
carbohydrate derivative metabolic processGO:19011352170.012
cell cycle phase transitionGO:00447701400.012
defense response to bacteriumGO:00427421780.012
regulation of cellular amide metabolic processGO:0034248390.012
regulation of cell developmentGO:00602842150.012
Fly
regulation of mapk cascadeGO:0043408920.012
response to alcoholGO:0097305950.012
response to extracellular stimulusGO:00099911160.012
response to organophosphorusGO:004668320.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
positive regulation of antimicrobial humoral responseGO:0002760280.012
regulation of molecular functionGO:00650092170.012
regulation of antimicrobial peptide productionGO:0002784440.012
regulation of cell divisionGO:0051302720.012
actin filament organizationGO:00070151260.012
sterol homeostasisGO:005509240.012
somatic muscle developmentGO:0007525660.012
peptidyl proline hydroxylationGO:001951110.012
cytokinesisGO:0000910900.012
deathGO:00162652840.012
regulation of cell shapeGO:00083601130.012
nephron epithelium developmentGO:007200930.012
cellular amine metabolic processGO:0044106120.012
regulation of cell differentiationGO:00455953020.011
Fly
adult locomotory behaviorGO:0008344760.011
cholesterol homeostasisGO:004263230.011
actin cytoskeleton organizationGO:00300362060.011
pole plasm rna localizationGO:0007316520.011
pole plasm assemblyGO:0007315610.011
regulation of cell deathGO:00109411730.011
positive regulation of cellular component organizationGO:00511301560.011
cellular response to oxygen containing compoundGO:1901701790.011
cellular response to ethanolGO:007136140.011
response to bacteriumGO:00096171980.011
rhythmic behaviorGO:0007622760.011
neuroblast proliferationGO:0007405740.011
glycerolipid catabolic processGO:004650330.011
mitotic cell cycle phase transitionGO:00447721380.011
regulation of mitosisGO:0007088560.011
benzene containing compound metabolic processGO:004253730.011
response to monosaccharideGO:003428440.011
organic cyclic compound catabolic processGO:19013611680.011
antimicrobial peptide biosynthetic processGO:0002777380.011
regulation of alternative mrna splicing via spliceosomeGO:0000381600.011
pole plasm oskar mrna localizationGO:0045451460.011
amine metabolic processGO:0009308120.011
morphogenesis of an epitheliumGO:00020092760.011
stem cell proliferationGO:0072089880.011
oocyte anterior posterior axis specificationGO:0007314720.011
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.011
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.011
intracellular mrna localization involved in pattern specification processGO:0060810560.011
ras protein signal transductionGO:0007265880.011
anatomical structure homeostasisGO:0060249970.011
mrna processingGO:00063971040.011
regulation of catalytic activityGO:00507901850.011
regulation of cellular component sizeGO:0032535980.011
protein phosphorylationGO:00064681690.011
cellular protein localizationGO:00346131600.011
posttranscriptional regulation of gene expressionGO:00106081450.011
negative regulation of protein metabolic processGO:0051248850.011
leg disc developmentGO:0035218920.011
respiratory system developmentGO:00605412130.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
ion transmembrane transportGO:00342201220.011
ion transportGO:00068111450.011
cell migrationGO:00164772380.011
positive regulation of protein metabolic processGO:00512471280.011
hematopoietic progenitor cell differentiationGO:000224410.011
cellular nitrogen compound catabolic processGO:00442701650.011
regulation of innate immune responseGO:0045088710.011
actin filament based processGO:00300292200.011
response to heatGO:0009408630.011
establishment of tissue polarityGO:0007164870.010
cell fate specificationGO:0001708710.010
Fly
regulation of apoptotic processGO:00429811300.010
male gamete generationGO:00482322010.010
rna splicing via transesterification reactionsGO:0000375730.010
positive regulation of multicellular organismal processGO:00512401430.010
small gtpase mediated signal transductionGO:0007264880.010
positive regulation of cellular protein metabolic processGO:00322701180.010
regulation of programmed cell deathGO:00430671520.010
response to hexoseGO:000974630.010
establishment of planar polarityGO:0001736870.010
positive regulation of catalytic activityGO:00430851180.010
intracellular mrna localizationGO:0008298660.010
positive regulation of intracellular signal transductionGO:19025331160.010
nephron morphogenesisGO:007202830.010
salivary gland developmentGO:00074311620.010
organelle localizationGO:00516401480.010
compound eye photoreceptor cell differentiationGO:00017511400.010
photoreceptor cell differentiationGO:00465301700.010
neural precursor cell proliferationGO:0061351750.010
spermatogenesisGO:00072832000.010
nephron tubule developmentGO:007208030.010
anion homeostasisGO:005508130.010
epiboly involved in wound healingGO:009050520.010
positive regulation of phosphorus metabolic processGO:00105621390.010
morphogenesis of a polarized epitheliumGO:0001738930.010
secretionGO:00469031090.010
mitotic spindle elongationGO:0000022810.010
aromatic compound catabolic processGO:00194391660.010
cell fate determinationGO:0001709910.010
sensory perception of painGO:001923340.010
chromatin organizationGO:00063252070.010
cuticle developmentGO:0042335860.010
g2 dna damage checkpointGO:0031572690.010

zen2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.017
renal tubular transport diseaseDOID:44700.014
urinary system diseaseDOID:1800.014
kidney diseaseDOID:55700.014
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.011
disease of cellular proliferationDOID:1456600.011
acquired metabolic diseaseDOID:006015800.011
carbohydrate metabolism diseaseDOID:005001300.010